What's it like in Uptown?

Uptown is a welcoming neighbourhood known for its array of dining options. Are you looking for Uptown travel tips? Make sure that you visit Fillmore Auditorium and Wells Fargo Center while you're in the neighbourhood.

What's the best hotel for a stay in Uptown?

Based on our traveller data, Hampton Inn & Suites Denver-Downtown is one of the top choices for your stay in Uptown. This hotel is a short 13-minute walk from Colorado Convention Center, and it offers free breakfast and an indoor pool. Another good option for your stay in the area is Warwick Denver .

How many hotels should I expect to find in the Uptown area?

Expedia has 32 hotels and other accommodation options in Uptown to choose from, making this an ideal home base for exploring the greater Denver area.

If I need to cancel my hotel reservation in Uptown, will I receive a refund?

Yes! The majority of hotel bookings are refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals in Uptown.

What is there to do in this Denver neighbourhood?

A few attractions you might want to check out while you're in Uptown are Fillmore Auditorium and Wells Fargo Center. While you're out sightseeing, Union Station and Empower Field at Mile High are a couple of additional sights to visit in Denver.

The Best Hotels in Uptown, Denver - 2026 Updated Prices

A city street with cars, buildings, and a church steeple.

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Our top choices for Uptown hotels

A swimming pool with inflatable toys, lounge chairs, and a mural on the wall.

1. Hampton Inn & Suites Denver-Downtown

Uptown

Monique

Rp1.956.281 total

includes taxes & fees

2 Nov - 3 Nov

A poolside area with lounge chairs, potted plants, and a waiter serving drinks.

2. Warwick Denver

Uptown

Ashley

Rp3.066.457 total

includes taxes & fees

25 Oct - 26 Oct

A corner bathroom with two copper sinks, ornate window frames, and a decorative ceiling light.

3. Urban Cowboy Denver

Uptown

Danielle

Rp4.233.109 total

includes taxes & fees

19 Oct - 20 Oct

A bar area with wooden chairs, a counter with bottles, and pendant lights.

4. Hyatt Place Denver Downtown

Downtown Denver, 1 km from Uptown

Victor

Rp2.571.052 total

includes taxes & fees

9 Nov - 10 Nov

A couple seated on a leather couch with a cityscape view through large windows.

5. Hyatt Regency Denver at Colorado Convention Center

Downtown Denver, 1.1 km from Uptown

Lesley

Rp4.379.085 total

includes taxes & fees

17 Oct - 18 Oct

A conference room with rows of tables and chairs, a projector screen, and chandeliers.

6. Sonesta Denver Downtown

Downtown Denver, 1 km from Uptown

Gary

Rp2.051.091 total

includes taxes & fees

1 Nov - 2 Nov

A hotel entrance with a stone facade and large windows.

7. Hyatt House Denver Downtown

Downtown Denver, 1 km from Uptown

Hailee

Rp2.879.815 total

includes taxes & fees

11 Nov - 12 Nov

A bar with a view of a cityscape, including a prominent building with a dome.

8. Populus

Downtown Denver, 0.9 km from Uptown

emanuela

Rp4.193.020 total

includes taxes & fees

31 Oct - 1 Nov

A modern hotel with a prominent sign, multiple floors, and a parking sign visible.

9. Home2 Suites by Hilton Denver Downtown Convention Center

Downtown Denver, 1.1 km from Uptown

Adriana

Rp2.533.317 total

includes taxes & fees

10 Nov - 11 Nov

A modern restaurant with a central bar area, multiple seating options, and a contemporary interior design.

10. Hyatt Centric Downtown Denver

Downtown Denver, 1 km from Uptown

Georgia

Rp2.879.815 total

includes taxes & fees

25 Oct - 26 Oct

A modern dining area with long communal tables, chairs, and a long counter.

11. Element by Marriott Denver Downtown East

1.3 km from Uptown

Steve

Rp2.527.609 total

includes taxes & fees

11 Nov - 12 Nov

A spacious restaurant with high ceilings, large windows, and a variety of seating options including tables and booths.

12. Hilton Garden Inn Denver Union Station, CO

LoDo, 2.2 km from Uptown

joni

Rp3.330.964 total

includes taxes & fees

25 Oct - 26 Oct

A couple relaxing by a poolside lounge chair with a city view, a hanging chair, and a pool with a 'No Swimming' sign.

13. The Rally Hotel at McGregor Square

LoDo, 1.8 km from Uptown

Richard

Rp5.409.987 total

includes taxes & fees

8 Nov - 9 Nov

A multi-story hotel with a modern architectural design, featuring large windows and a prominent entrance.

14. The Maven Hotel at Dairy Block

LoDo, 1.7 km from Uptown

Mitchell

Rp5.353.989 total

includes taxes & fees

8 Nov - 9 Nov

A lobby with a marble floor, a central staircase, and a reception desk.

15. Hotel Teatro

Downtown Denver, 1.5 km from Uptown

Rp3.294.608 total

includes taxes & fees

9 Nov - 10 Nov

A multi-story hotel with a prominent City Express sign, a covered entrance, and a brick facade.

16. City Express by Marriott Denver Airport

19.5 km from Uptown

Sharon

Rp2.197.835 total

includes taxes & fees

18 Oct - 19 Oct

A modern interior with a round table and chairs, wooden paneling, and a view through a glass door.

17. Hyatt Place Denver/Cherry Creek

6.4 km from Uptown

Paige

Rp2.597.639 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor seating area with orange cushions, a fire pit, and a pergola.

18. Hyatt House Denver/Lakewood at Belmar

9.2 km from Uptown

Amy

Rp2.672.170 total

includes taxes & fees

8 Nov - 9 Nov

A modern living room with a sectional sofa, ottomans, a coffee table, and a large window offering a view of buildings and greenery.

19. Vīb Hotel by Best Western Denver RiNo

River North Art District, 3.1 km from Uptown

Karah

Rp2.685.892 total

includes taxes & fees

1 Nov - 2 Nov

A modern kitchen with stainless steel appliances, wooden flooring, and a brick wall.

20. Catbird Hotel

3 km from Uptown

Susanna

Rp3.122.888 total

includes taxes & fees

25 Oct - 26 Oct

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Where to stay in Uptown

Find the best Uptown areas for the activities you enjoy most.

A modern architectural complex with geometric shapes and a prominent red sculpture.

Downtown Denver

Discover Denver is at its most dynamic in this central district, which has cool craft breweries, bars, galleries, boutiques and entertainment venues.

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A city street with a large canopy structure, modern buildings, and potted plants.

Cherry Creek

Abundant dining options and stunning river views are well-reviewed features of Cherry Creek. Make a stop by top sights like Cherry Creek Shopping Center while you're exploring the area.

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A cityscape with modern buildings and a forested area in the foreground.

Denver Tech Center

Known for its ample dining options and great live music, there's plenty to explore in Denver Tech Center. You can visit top attractions like Fiddler's Green Amphitheatre and The Landmark Theatre Greenwood Village, and jump on the metro at Orchard Station or Arapahoe at Village Center Station to see more of the city.

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A city skyline with a prominent stadium and surrounding high-rise buildings.

LoDo

Visitors often come to LoDo for its abundant dining options, but many stay to explore sights like Union Station and McGregor Square. Getting around the area on the metro is easy if you take a ride at Union Station-Coors Field-16th St. Mall Station.

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A rural landscape with a field of corn, a bridge, and houses in the background.

Highlands Ranch

Highlands Ranch is known for its abundant dining options, and you can plan a trip to South Suburban Sports Complex and Chatfield State Park while you're in town.

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Top Uptown Hotel Reviews

Hyatt Place Denver South/Park Meadows

10/10 Excellent

"We always enjoy our stay here. We stay here frequently and this time did not disappoint. Such a comfortable and enjoyable stay. It's always nice to see familiar faces with the employees that work there. It seems that employee retention is really high which explains why the staff is amazing! Happy employees translate out to happy guests."