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Our top choices for East Cooper Medical Center hotels

American cuisine
Cambria Hotel Mount Pleasant – Charleston

Cambria Hotel Mount Pleasant – Charleston

Cambria Hotel Mount Pleasant – Charleston
3.0 star property
2.3 km from East Cooper Medical Center
9.4 out of 10, Exceptional, (1809)
"Beautiful room, good staff"
United States
Queen
The price is Rp1.546.699
Rp1.784.163 total
includes taxes & fees
4 Jan - 5 Jan 2026
Cambria Hotel Mount Pleasant – Charleston
Lobby
Tru by Hilton Mt Pleasant Charleston

Tru by Hilton Mt Pleasant Charleston

Tru by Hilton Mt Pleasant Charleston
2.5 star property
2 km from East Cooper Medical Center
9.2 out of 10, Wonderful, (1460)
"It was a great hotel!"
United States
Alashia
The price is Rp1.492.110
Rp1.719.472 total
includes taxes & fees
1 Jan - 2 Jan 2026
Tru by Hilton Mt Pleasant Charleston
Bar (on property)
Hyatt House Charleston / Mount Pleasant

Hyatt House Charleston / Mount Pleasant

Hyatt House Charleston / Mount Pleasant
3.5 star property
2.4 km from East Cooper Medical Center
9.2 out of 10, Wonderful, (1001)
"Good value and great location."
United States
Howard
The price is Rp1.806.084
Rp2.078.668 total
includes taxes & fees
6 Jan - 7 Jan 2026
Hyatt House Charleston / Mount Pleasant
Exterior
Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG

Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG

Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG
2.5 star property
0.8 km from East Cooper Medical Center
9.0 out of 10, Wonderful, (1000)
"Everything about my stay here has been a delight, clean room, professional & friendly staff "
United States
John
The price is Rp1.469.072
Rp1.660.051 total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG
Restaurant
Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms

Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms

Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms
2.5 star property
0.3 km from East Cooper Medical Center
9.0 out of 10, Wonderful, (1000)
"Great place to stay!!!"
United States
Fredrick
The price is Rp1.478.421
Rp1.706.173 total
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms
Bar (on property)
Hyatt Place Mount Pleasant Towne Centre

Hyatt Place Mount Pleasant Towne Centre

Hyatt Place Mount Pleasant Towne Centre
3.0 star property
0.4 km from East Cooper Medical Center
9.0 out of 10, Wonderful, (1000)
"Nice place"
United States
Marcelle
The price is Rp1.836.340
Rp2.278.395 total
includes taxes & fees
7 Jan - 8 Jan 2026
Hyatt Place Mount Pleasant Towne Centre
Exterior
Home2 Suites By Hilton Mt Pleasant Charleston

Home2 Suites By Hilton Mt Pleasant Charleston

Home2 Suites By Hilton Mt Pleasant Charleston
3.0 star property
0.7 km from East Cooper Medical Center
8.8 out of 10, Excellent, (1000)
"Variety of breakfast options - hotel and room felt clean overall - lots of dining options nearby "
United States
Sarah
The price is Rp1.629.001
Rp1.840.771 total
includes taxes & fees
23 Dec - 24 Dec
Home2 Suites By Hilton Mt Pleasant Charleston
Free daily full breakfast
Residence Inn by Marriott Charleston Mount Pleasant

Residence Inn by Marriott Charleston Mount Pleasant

Residence Inn by Marriott Charleston Mount Pleasant
3.0 star property
0.4 km from East Cooper Medical Center
8.8 out of 10, Excellent, (183)
"Property was quiet and clean. It was convenient to dining and shopping options. Pool was very well maintained and breakfast was well-stocked and excellent each morning. "
United States
Holly
The price is Rp1.969.892
Rp2.225.978 total
includes taxes & fees
25 Dec - 26 Dec
Residence Inn by Marriott Charleston Mount Pleasant
Lobby lounge
Courtyard by Marriott Charleston Mount Pleasant

Courtyard by Marriott Charleston Mount Pleasant

Courtyard by Marriott Charleston Mount Pleasant
3.0 star property
1.9 km from East Cooper Medical Center
8.8 out of 10, Excellent, (1000)
"We had a very restful stay. The lady that checked us in was very nice. The room was very clean and the beds were comfortable. "
United States
Kathryn
The price is Rp1.686.094
Rp1.905.287 total
includes taxes & fees
1 Jan - 2 Jan 2026
Courtyard by Marriott Charleston Mount Pleasant
Restaurant
Homewood Suites by Hilton Charleston - Mt Pleasant

Homewood Suites by Hilton Charleston - Mt Pleasant

Homewood Suites by Hilton Charleston - Mt Pleasant
3.0 star property
1.5 km from East Cooper Medical Center
8.4 out of 10, Very good, (1003)
"Courteous staff and great location"
United States
Loushon
The price is Rp1.816.307
Rp2.085.814 total
includes taxes & fees
31 Dec - 1 Jan 2026
Homewood Suites by Hilton Charleston - Mt Pleasant
Exterior
Comfort Suites at Isle Of Palms Connector

Comfort Suites at Isle Of Palms Connector

Comfort Suites at Isle Of Palms Connector
2.5 star property
0.5 km from East Cooper Medical Center
8.2 out of 10, Very good, (1002)
"The staff was friendly and the room was exceptionally clean. "
United States
RAYMOND
The price is Rp1.386.437
Rp1.647.974 total
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Suites at Isle Of Palms Connector
Dining
DoubleTree by Hilton Charleston Mount Pleasant

DoubleTree by Hilton Charleston Mount Pleasant

DoubleTree by Hilton Charleston Mount Pleasant
4.0 star property
3.3 km from East Cooper Medical Center
9.2 out of 10, Wonderful, (1005)
"Room was nice and staff was very friendly."
United States
Viorel
The price is Rp1.492.110
Rp1.719.473 total
includes taxes & fees
1 Jan - 2 Jan 2026
DoubleTree by Hilton Charleston Mount Pleasant
Studio, 2 Queen Beds | Private kitchen | Fridge, microwave, stovetop, dishwasher
TownePlace Suites Charleston Mt. Pleasant

TownePlace Suites Charleston Mt. Pleasant

TownePlace Suites Charleston Mt. Pleasant
3.0 star property
3.2 km from East Cooper Medical Center
9.0 out of 10, Wonderful, (523)
"Great place to stay. Dog friendly. "
United States
Gabriela
The price is Rp1.836.340
Rp2.075.065 total
includes taxes & fees
28 Dec - 29 Dec
TownePlace Suites Charleston Mt. Pleasant
Terrace/patio
French Quarter Inn

French Quarter Inn

French Quarter Inn
4.0 star property
11.1 km from East Cooper Medical Center
10.0 out of 10, Exceptional, (1005)
"Phenomenal stay - highly recommend"
United States
Patricia
French Quarter Inn
Ballroom
Staybridge Suites Charleston - Mount Pleasant by IHG

Staybridge Suites Charleston - Mount Pleasant by IHG

Staybridge Suites Charleston - Mount Pleasant by IHG
3.0 star property
7.2 km from East Cooper Medical Center
9.4 out of 10, Exceptional, (1000)
"Great location and very friendly staff"
United States
Malav
The price is Rp1.836.340
Rp2.111.456 total
includes taxes & fees
25 Dec - 26 Dec
Staybridge Suites Charleston - Mount Pleasant by IHG
Courtyard
Hilton Club Liberty Place Charleston

Hilton Club Liberty Place Charleston

Hilton Club Liberty Place Charleston
3.5 star property
10.7 km from East Cooper Medical Center
9.8 out of 10, Exceptional, (886)
"Wonderful two bedroom suite and room was cleaned daily - wonderful location as well."
United States
Liz
The price is Rp3.547.642
Rp4.044.312 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton Club Liberty Place Charleston
Terrace/patio
Holiday Inn Express & Suites Mt. Pleasant by IHG

Holiday Inn Express & Suites Mt. Pleasant by IHG

Holiday Inn Express & Suites Mt. Pleasant by IHG
3.5 star property
6.8 km from East Cooper Medical Center
9.2 out of 10, Wonderful, (1000)
"Great room layout and wonderful breakfast. "
United States
Clara
The price is Rp1.435.684
Rp1.660.387 total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Mt. Pleasant by IHG
Front of property
The Spectator Hotel

The Spectator Hotel

The Spectator Hotel
4.0 star property
11 km from East Cooper Medical Center
9.8 out of 10, Exceptional, (983)
"Excellent 5 star hotel"
United States
John
The Spectator Hotel
Terrace/patio
The Nickel Hotel

The Nickel Hotel

The Nickel Hotel
4.0 star property
11.4 km from East Cooper Medical Center
9.8 out of 10, Exceptional, (81)
"Beautiful hotel!! Close to shopping and dining! Highly recommended!!"
United States
Matthew
The price is Rp3.993.205
Rp4.587.978 total
includes taxes & fees
5 Jan - 6 Jan 2026
The Nickel Hotel
Terrace/patio
Home2 Suites by Hilton Charleston Daniel Island

Home2 Suites by Hilton Charleston Daniel Island

Home2 Suites by Hilton Charleston Daniel Island
3.0 star property
8.7 km from East Cooper Medical Center
9.4 out of 10, Exceptional, (500)
"So clean, great amenities and excellent breakfast. "
United States
Susan
The price is Rp2.039.673
Rp2.325.225 total
includes taxes & fees
3 Jan - 4 Jan 2026
Home2 Suites by Hilton Charleston Daniel Island
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top East Cooper Medical Center Hotel Reviews

Hotels near other East Cooper Medical Center attractions

Boone Hall Plantation and Gardens

4.6/5 (518 reviews)
Find out about the history of Mount Pleasant with a stop at Boone Hall Plantation and Gardens. Stroll along the area's waterfront or simply savour its top-notch restaurants.
See properties

Regal Palmetto Grande

You can take time to visit Regal Palmetto Grande during your travels to Mount Pleasant. Wander the area's riverfront or simply enjoy one of its top-notch restaurants.
See properties

Frequently asked questions

What's the area like around East Cooper Medical Center?
East Cooper Medical Center is located in Mount Pleasant. This historic area is known for its stunning river views and array of dining options. If you're looking for a convenient place to stay, take a look at the 26 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to East Cooper Medical Center?
Adjacent to East Cooper Medical Center, Hyatt Place Mount Pleasant Towne Centre is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a restaurant. Other good options close by include Home2 Suites By Hilton Mt Pleasant Charleston and Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms.
How many hotels will I find close to East Cooper Medical Center?
Expedia has 26 hotels and other accommodation options within a mile from East Cooper Medical Center.
If I need to cancel the hotel reservation for my stay near East Cooper Medical Center, will I receive a refund?
Yes, you'll find most hotel bookings are refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to view the best deals available near East Cooper Medical Center.
What can I see and do near East Cooper Medical Center?
Learn about local history at Charles Pinckney National Historic Site and Pitt Street Bridge. You can enjoy live performances at Crabpot Players Theatre and Cinebarre Mount Pleasant. Spend some time wandering around Shem Creek Park, Mount Pleasant Memorial Waterfront Park and Palmetto Islands County Park.