Search Hotels near Florence Regional Airport (FLO), Florence

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Our top choices for ${destinationAirportFriendlyName} hotels

Front of property – evening/night
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
3.5 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (1002)
"Great experience in a nice hotel in downtown."
United States
HATIM
The price is Rp1.674.100
Rp1.874.992 total
includes taxes & fees
19 Jan - 20 Jan 2026
Hyatt Place Florence Downtown
Bar (on property)
Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
3.0 star property
3.6 km from Florence, SC (FLO-Florence Regional)
8.8 out of 10, Excellent, (606)
"Special place. Great staff with an outstanding restaurant "
United States
John D
The price is Rp2.182.692
Rp2.444.614 total
includes taxes & fees
11 Jan - 12 Jan 2026
Hotel Florence, Tapestry Collection by Hilton
Exterior
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
8 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (2203)
"Breakfast was great, room very clean ."
United States
Leann
The price is Rp1.416.289
Rp1.586.243 total
includes taxes & fees
18 Jan - 19 Jan 2026
Park Inn by Radisson Florence, SC
Lobby
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
8 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (2511)
"I nice place to stay, very quiet, good breakfast, nice staff, spotless room. "
United States
Timothy
The price is Rp1.054.683
Rp1.181.245 total
includes taxes & fees
28 Dec - 29 Dec
Howard Johnson by Wyndham Florence
Lobby
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
9.6 km from Florence, SC (FLO-Florence Regional)
9.2 out of 10, Wonderful, (1170)
"Great location, friendly staff. "
United States
Defelicio
The price is Rp1.638.108
Rp1.834.683 total
includes taxes & fees
11 Jan - 12 Jan 2026
Comfort Inn & Suites Florence Center Area
Exterior
Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
8.2 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (820)
"We had our dog and the room was good and dog amenities helpful."
United States
Cynthia
The price is Rp1.920.598
Rp2.151.070 total
includes taxes & fees
7 Jan - 8 Jan 2026
Hampton Inn & Suites Florence-North-I-95
Terrace/patio
Tru by Hilton Florence I-95

Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
8.3 km from Florence, SC (FLO-Florence Regional)
8.4 out of 10, Very good, (1002)
"We enjoyed our stay. Everything stood out Staff, Clean room and Amenities. "
United States
Marita
The price is Rp1.564.949
Rp1.811.504 total
includes taxes & fees
1 Jan - 2 Jan 2026
Tru by Hilton Florence I-95
Exterior
La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
3.0 star property
8.1 km from Florence, SC (FLO-Florence Regional)
8.0 out of 10, Very good, (1667)
"Clean room & breakfast was good. Checkin staff was great, friendly and professional. "
United States
Cheryl
The price is Rp1.565.283
Rp1.753.119 total
includes taxes & fees
28 Dec - 29 Dec
La Quinta Inn & Suites by Wyndham Florence
Exterior
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2.5 star property
8.3 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (1005)
"Room was clean, staff was courteous and breakfast was great !"
United States
Angela
The price is Rp1.908.474
Rp2.137.491 total
includes taxes & fees
25 Jan - 26 Jan 2026
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
View from property
Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
2.5 star property
9.6 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (559)
"Clean room, professional and courteous staff. "
United States
Felicia
The price is Rp1.835.651
Rp2.055.930 total
includes taxes & fees
25 Jan - 26 Jan 2026
Fairfield Inn & Suites by Marriott Florence I-20
Exterior
Comfort Suites Florence I-95

Comfort Suites Florence I-95

Comfort Suites Florence I-95
2.5 star property
8.3 km from Florence, SC (FLO-Florence Regional)
8.4 out of 10, Very good, (1000)
"Pool was clean good breakfast "
United States
Ann
The price is Rp1.717.627
Rp1.990.706 total
includes taxes & fees
25 Jan - 26 Jan 2026
Comfort Suites Florence I-95
Exterior
Microtel Inn & Suites by Wyndham Florence

Microtel Inn & Suites by Wyndham Florence

Microtel Inn & Suites by Wyndham Florence
2.0 star property
8.5 km from Florence, SC (FLO-Florence Regional)
6.8 out of 10, (1002)
"Good stay "
United States
Jimmy
The price is Rp1.004.460
Rp1.124.995 total
includes taxes & fees
29 Dec - 30 Dec
Microtel Inn & Suites by Wyndham Florence
View from property
Residence Inn Marriott Florence

Residence Inn Marriott Florence

Residence Inn Marriott Florence
3.0 star property
9.9 km from Florence, SC (FLO-Florence Regional)
8.8 out of 10, Excellent, (486)
"Yes our stay was great big variety on breakfast clean hotel rooms nice to have a kitchen had a great day"
United States
Marialinda
The price is Rp1.660.707
Rp1.859.992 total
includes taxes & fees
31 Dec - 1 Jan 2026
Residence Inn Marriott Florence
Free daily on-the-go breakfast
Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North
2.0 star property
8.3 km from Florence, SC (FLO-Florence Regional)
6.8 out of 10, (1001)
"Clean room , quite area , walking distance "
United States
Gisell
The price is Rp981.860
Rp1.099.549 total
includes taxes & fees
12 Jan - 13 Jan 2026
Days Inn by Wyndham Florence/I-95 North
Exterior
TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
3.0 star property
9.7 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (708)
"Good stay, great staff"
United States
James
The price is Rp1.727.671
Rp1.934.991 total
includes taxes & fees
29 Dec - 30 Dec
TownePlace Suites by Marriott Florence
Reception
Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
2.5 star property
9.9 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (826)
"My go to stay while in Fairfax. "
United States
Gregory
The price is Rp1.633.587
Rp1.829.618 total
includes taxes & fees
25 Jan - 26 Jan 2026
Hampton Inn & Suites Florence Center
Lobby sitting area
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
8 km from Florence, SC (FLO-Florence Regional)
8.0 out of 10, Very good, (29)
"Friendly staff and clean environment "
United States
john
The price is Rp1.633.587
Rp1.895.746 total
includes taxes & fees
6 Jan - 7 Jan 2026
Spark by Hilton Florence North I-95, SC
Desk, blackout curtains, iron/ironing board, free WiFi
SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence
3.0 star property
9.8 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (973)
"Staff was very friendly, safe and clean room in an area with plenty to do fir shopping and eating"
United States
Michael
The price is Rp1.802.838
Rp2.019.179 total
includes taxes & fees
29 Dec - 30 Dec
SpringHill Suites by Marriott Florence
Indoor pool
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 star property
10.7 km from Florence, SC (FLO-Florence Regional)
9.2 out of 10, Wonderful, (1002)
"Very good breakfast & convenient location"
United States
Diedre
The price is Rp1.841.510
Rp2.062.493 total
includes taxes & fees
25 Jan - 26 Jan 2026
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Exterior
Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
3.0 star property
10.7 km from Florence, SC (FLO-Florence Regional)
9.4 out of 10, Exceptional, (931)
"Friendly staff, great breakfast, beautiful ammenities!"
United States
Brandi
The price is Rp2.260.035
Rp2.531.239 total
includes taxes & fees
25 Jan - 26 Jan 2026
Staybridge Suites Florence - Civic Center by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Florence Regional Hotel Reviews

Rodeway Inn Florence Downtown

Rodeway Inn Florence Downtown

10/10 Excellent
"Good"
Joshua 1-night trip
Posted 3 months ago
Rodeway Inn Florence Downtown

Guide to exploring Florence Regional

Florence Regional hotels information

Number of reviews
20,490
Accommodation
117 hotels
Lowest Price
Rp1.099.549
Highest Price
Rp2.531.239

Frequently asked questions

What's the area like near Florence, SC (FLO-Florence Regional)?

Florence, SC (FLO-Florence Regional) is located in a welcoming area of Florence known for its array of dining options. You'll find 58 hotels and other accommodations within a few miles of the airport for a convenient home base.

Where is the best place to stay close to Florence, SC (FLO-Florence Regional)?

Hyatt Place Florence Downtown is one of the top choices for your stay and is a popular hotel, featuring free breakfast and free WiFi. It's located 2.2 mi (3.5 km) from Florence, SC (FLO-Florence Regional). Other choices near the airport include Hotel Florence, Tapestry Collection by Hilton and Rodeway Inn Florence Downtown.

How many hotels can I expect to find close to Florence, SC (FLO-Florence Regional)?

Expedia has 58 hotels and other accommodation options a few miles from the airport.