Aerial far photo of Matlacha Florida a touristy travel destination town

Search Hotels in Matlacha Isles, Cape Coral

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
14 Aug - 16 Aug
Next weekend
21 Aug - 23 Aug

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Matlacha Isles hotels

Interior

1. Holiday Inn Express & Suites Fort Myers Airport by IHG

Holiday Inn Express & Suites Fort Myers Airport by IHG
2.5 star property
29 km from Matlacha Isles
9.6 out of 10, Exceptional, (1,180 reviews)
"Great place to stay."
United States
Brandon
The price is Rp1.628.627
Rp1.816.009 total
includes taxes & fees
4 Sept - 5 Sept
Holiday Inn Express & Suites Fort Myers Airport by IHG
BBQ/picnic Area

2. Matlacha on Shoreview

Matlacha on Shoreview
2.0 star property
1.4 km from Matlacha Isles
9.6 out of 10, Exceptional, (286 reviews)
"Great location very well kept clean will be back soon."
United States
Robby
The price is Rp1.163.305
Rp2.494.395 total
includes taxes & fees
1 Sept - 2 Sept
Matlacha on Shoreview
Desk, iron/ironing board, free WiFi, bed sheets

3. SpringHill Suites by Marriott Fort Myers Airport

SpringHill Suites by Marriott Fort Myers Airport
3.0 star property
27.1 km from Matlacha Isles
8.6 out of 10, Excellent, (1,009 reviews)
"It was a great place to stay and the staff was helpful . Very clean and we definitely will stay there again in the future."
United States
Samantha
The price is Rp1.592.833
Rp1.776.009 total
includes taxes & fees
24 Aug - 25 Aug
SpringHill Suites by Marriott Fort Myers Airport
Lobby

4. Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
2.0 star property
28 km from Matlacha Isles
8.2 out of 10, Very good, (1,757 reviews)
"I love that hotel and the staff"
United States
Keilyn
The price is Rp1.240.262
Rp1.382.892 total
includes taxes & fees
11 Aug - 12 Aug
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
Exterior

5. Hyatt Place Fort Myers/at The Forum

Hyatt Place Fort Myers/at The Forum
3.0 star property
24.7 km from Matlacha Isles
8.2 out of 10, Very good, (1,006 reviews)
"Clean, quiet, and nicely appointed rooms!"
United States
Ken
The price is Rp1.199.099
Rp1.336.995 total
includes taxes & fees
16 Aug - 17 Aug
Hyatt Place Fort Myers/at The Forum
Exterior

6. Best Western Fort Myers Inn & Suites

Best Western Fort Myers Inn & Suites
2.5 star property
20.8 km from Matlacha Isles
8.8 out of 10, Excellent, (1,227 reviews)
"The staff was so nice and accommodating. Close to restaurants and features we were interested in."
United States
Florence
The price is Rp1.176.012
Rp1.311.253 total
includes taxes & fees
6 Sept - 7 Sept
Best Western Fort Myers Inn & Suites
Restaurant

7. Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers

Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers
3.0 star property
Hancock, 11.5 km from Matlacha Isles
9.4 out of 10, Exceptional, (864 reviews)
"Stayed here many times. Great location, staff is wonderful, rooms and property is clean. I also feel this is a nice safe location."
United States
David
The price is Rp1.886.344
Rp2.103.274 total
includes taxes & fees
13 Aug - 14 Aug
Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers
Exterior

8. Homewood Suites by Hilton - Fort Myers

Homewood Suites by Hilton - Fort Myers
3.0 star property
20.6 km from Matlacha Isles
9.2 out of 10, Wonderful, (1,011 reviews)
"Great hotel and great location"
United States
Fathi
The price is Rp1.782.541
Rp1.987.534 total
includes taxes & fees
30 Aug - 31 Aug
Homewood Suites by Hilton - Fort Myers
Front of property

9. Angler's Inn

Angler's Inn
2.5 star property
2.5 km from Matlacha Isles
9.4 out of 10, Exceptional, (335 reviews)
"Just a great Air B&B in a small fishing village .perfect stay and we will definitely return."
United States
Paul
The price is Rp2.774.035
Rp3.093.139 total
includes taxes & fees
11 Aug - 12 Aug
Angler's Inn
Indoor pool

10. Comfort Inn & Suites Fort Myers Airport

Comfort Inn & Suites Fort Myers Airport
2.5 star property
27.9 km from Matlacha Isles
8.8 out of 10, Excellent, (1,146 reviews)
"Staff was great and so was the hotel"
United States
Stephanie
The price is Rp1.221.470
Rp1.361.938 total
includes taxes & fees
23 Aug - 24 Aug
Comfort Inn & Suites Fort Myers Airport
Free continental breakfast on weekdays

11. Hampton Inn & Suites Fort Myers - Colonial Blvd

Hampton Inn & Suites Fort Myers - Colonial Blvd
2.5 star property
21 km from Matlacha Isles
9.4 out of 10, Exceptional, (1,005 reviews)
"Hampton Inns are my go to. Always clean, friendly and great breakfast."
United States
Tania
The price is Rp1.746.389
Rp1.947.223 total
includes taxes & fees
16 Aug - 17 Aug
Hampton Inn & Suites Fort Myers - Colonial Blvd
Terrace/patio

12. Home2 Suites by Hilton Fort Myers Airport

Home2 Suites by Hilton Fort Myers Airport
3.0 star property
30.1 km from Matlacha Isles
9.2 out of 10, Wonderful, (509 reviews)
"We enjoyed our visit great place"
United States
Elio
The price is Rp1.819.767
Rp2.029.040 total
includes taxes & fees
19 Aug - 20 Aug
Home2 Suites by Hilton Fort Myers Airport
Free buffet breakfast

13. Holiday Inn Express Hotel & Suites Fort Myers East - The Forum by IHG

Holiday Inn Express Hotel & Suites Fort Myers East - The Forum by IHG
2.5 star property
25.5 km from Matlacha Isles
8.4 out of 10, Very good, (1,007 reviews)
"The property is well maintained and the staff was helpful I recommend this Hotel to everyone."
United States
Victor
The price is Rp1.771.803
Rp1.975.650 total
includes taxes & fees
30 Aug - 31 Aug
Holiday Inn Express Hotel & Suites Fort Myers East - The Forum by IHG
Reception

14. Americas Best Value Inn Ft. Myers

Americas Best Value Inn Ft. Myers
3.0 star property
19.3 km from Matlacha Isles
7.6 out of 10, Good, (1,265 reviews)
"Great an clean"
United States
Ashley
The price is Rp1.284.826
Rp1.432.580 total
includes taxes & fees
3 Sept - 4 Sept
Americas Best Value Inn Ft. Myers
Property amenity

15. TownePlace Suites by Marriott Fort Myers Gulf Coast

TownePlace Suites by Marriott Fort Myers Gulf Coast
3.0 star property
29.9 km from Matlacha Isles
9.2 out of 10, Wonderful, (236 reviews)
"Everyone and everything was spectacular ! …"
United States
Jameasha
The price is Rp1.753.906
Rp1.955.605 total
includes taxes & fees
15 Aug - 16 Aug
TownePlace Suites by Marriott Fort Myers Gulf Coast
Desk, laptop workspace, iron/ironing board, free WiFi

16. Spark by Hilton Fort Myers

Spark by Hilton Fort Myers
2.5 star property
26.3 km from Matlacha Isles
9.4 out of 10, Exceptional, (9 reviews)
"Easy to check in, rooms are clean."
United States
Joshua
The price is Rp1.027.288
Rp1.145.425 total
includes taxes & fees
1 Sept - 2 Sept
Spark by Hilton Fort Myers
Bar (on property)

17. Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops
4.0 star property
20.6 km from Matlacha Isles
9.0 out of 10, Wonderful, (1,176 reviews)
"Always a great place to stay."
United States
heather
The price is Rp1.687.675
Rp1.881.757 total
includes taxes & fees
23 Aug - 24 Aug
Doubletree by Hilton Fort Myers at Bell Tower Shops
Lobby

18. Courtyard by Marriott Fort Myers Cape Coral

Courtyard by Marriott Fort Myers Cape Coral
3.0 star property
20.4 km from Matlacha Isles
8.2 out of 10, Very good, (1,009 reviews)
"It was fantastic nice and relaxed"
Canada
Mark
The price is Rp1.360.172
Rp1.516.592 total
includes taxes & fees
8 Sept - 9 Sept
Courtyard by Marriott Fort Myers Cape Coral
Lobby

19. Extended Stay America Premier Suites - Fort Myers - Airport

Extended Stay America Premier Suites - Fort Myers - Airport
2.5 star property
23.6 km from Matlacha Isles
9.0 out of 10, Wonderful, (1,080 reviews)
"I say here everytime I come to Florida good prices nice staff i love it here"
United States
Jakia
The price is Rp1.062.903
Rp1.185.139 total
includes taxes & fees
16 Aug - 17 Aug
Extended Stay America Premier Suites - Fort Myers - Airport
Suite, 1 King Bed, Non Smoking | Desk, laptop workspace, iron/ironing board, free WiFi

20. Comfort Inn Fort Myers Northeast

Comfort Inn Fort Myers Northeast
2.5 star property
25.8 km from Matlacha Isles
7.8 out of 10, Good, (752 reviews)
"Clean, smell good and comfortable rooms."
United States
Rosa
The price is Rp1.073.820
Rp1.197.310 total
includes taxes & fees
6 Sept - 7 Sept
Comfort Inn Fort Myers Northeast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Matlacha Isles

Find the best Matlacha Isles areas for the activities you enjoy most.
A pier extending into the water with two gazebos at the end, under a sunset sky.

Pelican

While visiting Pelican, you might make a stop by sights like Tarpon Point and Chabad Jewish Center.

A coastal residential area with a marina, dense greenery, and high-rise buildings in the background.

Caloosahatchee

If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing.

A sunset over a calm lake with a dock and palm trees.

Yacht Club

While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Dolphin Marina are some notable places to visit nearby.

A coastal cityscape with a beach, marina, and dense urban area.

Hancock

While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Sun Splash Water Park.

A wooden pier extending into calm water with a clear sky and distant land.

Burnt Store

When in Burnt Store, you can plan a visit to Coral Oaks Golf Course and Lovegrove Gallery & Gardens, some noteworthy sights in the nearby area.

Top Matlacha Isles Hotel Reviews

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

8/10 Good
"We had 1 day when water was coming into the bathroom and kitchen area because of the rain with wind over 45 mph. 1 other night there was water coming from the ceiling in the bathroom due to the floor above us. We stayed in a suite it was nice and would stay again. Just a little inconvenient when you’re on vacation. Maintenance was very prompt and polite."
Mike 5-night trip
Posted 3 hours ago
Lani Kai Beachfront Resort

Frequently asked questions

What is Matlacha Isles like?
Travellers will be sure to find plenty to entertain them in Cape Coral's Matlacha Isles neighbourhood.
How many hotels will I be able to find in the Matlacha Isles area?
When you want to put your feet up after a day of exploring the sights in Cape Coral, you can choose from 17 Expedia hotels and other accommodation options in Matlacha Isles.
If I need to cancel my hotel reservation in Matlacha Isles, will I receive a refund?
Yes, the majority of room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and get a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to get the best deals in Matlacha Isles.
What are the top things to see and do in Matlacha Isles?
A few places to visit in the area around Matlacha Isles include Griffen American Center for Haitian Art, Lovegrove Gallery & Gardens and Cape Royal Golf Club. While you're out sightseeing in Cape Coral, make sure that you visit other sights such as Little Dead Key or Big Dead Key.