Search Hotels in Midtown, St. Louis

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Our top choices for Midtown hotels

Element St. Louis Midtown

Element St. Louis Midtown
3.0 star property
Midtown
9.0 out of 10, Wonderful, (643)
"Everything was excellent. The staff were very friendly and helpful. The accommodations were excellent and it was a great location near every where we were going."
United States
Angela
The price is Rp2.263.856
Rp2.647.104 total
includes taxes & fees
21 Dec - 22 Dec
Element St. Louis Midtown

Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown
3.0 star property
Midtown
7.8 out of 10, Good, (1002)
"Ok"
United States
Shamari
The price is Rp1.831.060
Rp2.177.662 total
includes taxes & fees
21 Dec - 22 Dec
Residence Inn by Marriott St Louis Downtown

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 3.4 km from Midtown
8.4 out of 10, Very good, (4013)
"Arch view room is big and comfortable fantastic. . "
United States
Tim
The price is Rp1.400.761
Rp1.651.903 total
includes taxes & fees
28 Dec - 29 Dec
Hyatt Regency St. Louis at The Arch

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis, 3 km from Midtown
8.8 out of 10, Excellent, (1152)
"Really nice hotel!"
United States
DARIN
The price is Rp1.453.196
Rp1.728.272 total
includes taxes & fees
18 Dec - 19 Dec
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 3.4 km from Midtown
9.4 out of 10, Exceptional, (3282)
"Our stay was very enjoyable. Location was great and kids loved the indoor pool!"
United States
Christy
The price is Rp2.247.044
Rp2.627.446 total
includes taxes & fees
19 Dec - 20 Dec
Drury Plaza Hotel St. Louis at the Arch

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
17.3 km from Midtown
9.4 out of 10, Exceptional, (2763)
"The room was clean and staff were very friendly."
United States
Denise
The price is Rp1.497.974
Rp1.763.477 total
includes taxes & fees
19 Dec - 20 Dec
Pear Tree Inn St. Louis Airport

Holiday Inn Express Troy by IHG

Holiday Inn Express Troy by IHG
2.5 star property
29.4 km from Midtown
9.4 out of 10, Exceptional, (701)
"Great breakfast ! "
United States
Jeanette
The price is Rp1.697.892
Rp1.884.320 total
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Express Troy by IHG

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
3.0 star property
24.5 km from Midtown
7.4 out of 10, Good, (1003)
"Clean lobby, super friendly staff, effortless check in. There’s even a small market with food and essentials right next to the check in desk. "
United States
Jen
The price is Rp1.066.675
Rp1.237.216 total
includes taxes & fees
5 Jan - 6 Jan 2026
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
11.9 km from Midtown
9.0 out of 10, Wonderful, (1448)
"Awesome place to stay!!"
United States
Kaitlyn
The price is Rp1.464.682
Rp1.946.583 total
includes taxes & fees
21 Dec - 22 Dec
River City Casino & Hotel

Pear Tree Inn St. Louis Convention Center

Pear Tree Inn St. Louis Convention Center
3.0 star property
Downtown St. Louis, 3.3 km from Midtown
9.0 out of 10, Wonderful, (1053)
"It was perfect for our stay in St. Louis to visit the arch."
United States
Jacob
The price is Rp1.564.558
Rp1.829.395 total
includes taxes & fees
19 Dec - 20 Dec
Pear Tree Inn St. Louis Convention Center

The Principal Hotel

The Principal Hotel
3.5 star property
21.3 km from Midtown
9.8 out of 10, Exceptional, (191)
"Great place. Very nice rooms, new and clean."
United States
Jeff
The price is Rp1.877.835
Rp2.084.079 total
includes taxes & fees
17 Dec - 18 Dec
The Principal Hotel

Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown
2.5 star property
Downtown West, 2.5 km from Midtown
7.6 out of 10, Good, (591)
"Breakfast was delicious and room was comfy "
United States
Ronnesha
The price is Rp1.352.321
Rp1.581.254 total
includes taxes & fees
4 Jan - 5 Jan 2026
Tru By Hilton St. Louis Downtown

Best Western Plus St. Louis Airport Hotel

Best Western Plus St. Louis Airport Hotel
2.5 star property
16 km from Midtown
9.2 out of 10, Wonderful, (1002)
"Room was nice and comfortable, pool was awesome, and breakfast left us all happy"
United States
Letez
The price is Rp1.825.234
Rp2.257.659 total
includes taxes & fees
19 Dec - 20 Dec
Best Western Plus St. Louis Airport Hotel

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
9.8 km from Midtown
8.8 out of 10, Excellent, (3034)
"Clean room, good breakfast and good location "
United States
Martin
The price is Rp1.496.775
Rp1.747.305 total
includes taxes & fees
21 Dec - 22 Dec
Clayton Plaza Hotel & Extended Stay

Hampton Inn St. Louis - Columbia

Hampton Inn St. Louis - Columbia
2.5 star property
21.2 km from Midtown
8.6 out of 10, Excellent, (476)
"Breakfast was great and a very good atten"
United States
John
The price is Rp1.451.531
Rp1.610.909 total
includes taxes & fees
5 Jan - 6 Jan 2026
Hampton Inn St. Louis - Columbia

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis, 3.1 km from Midtown
8.8 out of 10, Excellent, (1243)
"Great hospitality"
United States
Alejandro
The price is Rp1.784.451
Rp2.122.229 total
includes taxes & fees
21 Dec - 22 Dec
Embassy Suites by Hilton St. Louis Downtown

Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG
2.5 star property
27.8 km from Midtown
9.2 out of 10, Wonderful, (818)
"Always a good stay here!"
United States
Chelsie
The price is Rp1.930.936
Rp2.220.190 total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Edwardsville by IHG

Quality Inn O'Fallon IL - St. Louis

Quality Inn O'Fallon IL - St. Louis
3.0 star property
24.3 km from Midtown
7.4 out of 10, Good, (1004)
"Bed was comfortable, room was quiet, breakfast had limited options and bathroom was tiny. Overall great value for the price! "
United States
Alison
The price is Rp777.368
Rp893.817 total
includes taxes & fees
16 Dec - 17 Dec
Quality Inn O'Fallon IL - St. Louis

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis
3.5 star property
25.8 km from Midtown
8.4 out of 10, Very good, (2221)
"Front staff was very friendly and very helpful. Check-in and check out was smooth and very easy. "
United States
James
The price is Rp1.747.664
Rp2.280.668 total
includes taxes & fees
6 Jan - 7 Jan 2026
Hollywood Casino & Hotel St. Louis

Courtyard by Marriott St. Louis Downtown/Convention Center

Courtyard by Marriott St. Louis Downtown/Convention Center
3.0 star property
Downtown St. Louis, 2.9 km from Midtown
9.0 out of 10, Wonderful, (1010)
"Was a great stay. "
United States
Lorilyn
The price is Rp1.683.743
Rp2.002.459 total
includes taxes & fees
21 Dec - 22 Dec
Courtyard by Marriott St. Louis Downtown/Convention Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Midtown

Find the best Midtown areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

Top Midtown Hotel Reviews

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Frequently asked questions

What is Midtown like?
Travellers are sure to enjoy a stay in St. Louis's Midtown neighbourhood. Make sure that you visit Chaifetz Arena and Washington Avenue Historic District as part of your Midtown travel plans.
Where is the best place to stay in Midtown?
Based on Expedia customer reviews, Element St. Louis Midtown is the highest ranked property in Midtown. This hotel offers free breakfast and an indoor pool. Another top choice in the area is Residence Inn by Marriott St Louis Downtown.
How many hotels will I be able to find in the Midtown area?
If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 30 Midtown hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Midtown, will I receive a refund?
Yes! Most hotel room reservations are refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to get top deals in Midtown.
What are the top things to see and do in Midtown?
Explore Midtown's landmarks such as Washington Avenue Historic District, Samuel Cupples House and Scott Joplin House State Historic Site and learn about the local history. Chaifetz Arena and Topgolf are also a couple of places to visit in the neighbourhood. St. Louis Union Station and Gateway Arch are some popular places to visit in the area around Midtown. While you're out sightseeing, .ZACK Theater and The MOTO Museum are a couple of additional sights to visit in St. Louis.
How can I get around Midtown and the greater St. Louis area?
Ready to get out and explore the city? Grand Station is the closest metro station.