Search Luxury Hotels in Mytilene

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Our top choices for Mytilene luxury hotels

1. Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel
4.0 star property
Lesvos
9.6 out of 10, Exceptional, (176 reviews)
  • cleanliness
    Luxuriate in this Lesvos boutique haven where pillowtop beds meet spa indulgences, all within steps of the beach and local art.
The price is Rp1.987.481
Rp2.237.575 total
includes taxes & fees
22 Nov - 23 Nov
Theofilos Paradise Boutique Hotel

2. Mythical Coast Wellness Retreat

Mythical Coast Wellness Retreat
5.0 star property
Lesvos
8.6 out of 10, Excellent, (74 reviews)
  • cleanliness
    Seaside luxury awaits at this Greek retreat, where beachfront bliss meets wellness indulgence with 3 indoor pools and a full-service spa.
The price is Rp1.704.110
Rp1.947.286 total
includes taxes & fees
18 Nov - 19 Nov
Mythical Coast Wellness Retreat

3. Elysion Hotel

Elysion Hotel
5.0 star property
Lesvos
9.2 out of 10, Wonderful, (51 reviews)
  • cleanliness
    Experience tranquil luxury and refined comfort at this 5-star seaside retreat with outdoor tennis courts and multiple dining options.
The price is Rp1.574.770
Rp2.308.845 total
includes taxes & fees
27 Nov - 28 Nov
Elysion Hotel

4. Elies Residences

Elies Residences
Lesvos
9.8 out of 10, Exceptional, (38 reviews)
The price is Rp1.984.594
Rp2.183.879 total
includes taxes & fees
12 Dec - 13 Dec
Elies Residences
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently Asked Questions

Are you looking for a luxury hotel for your Mytilene holiday?

Mytilene has some interesting things to see and do including Port of Mytilene and Mytilini Castle, so you might want to take in the local sights during your visit.

What's the best luxury hotel in Mytilene?

Elysion Hotel is a luxury hotel with 2 restaurants and 2 bars, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Mythical Coast Wellness Retreat and Theofilos Paradise Boutique Hotel are two other upscale options for your stay.

When can I expect good weather in Mytilene?

Planning for the weather is a good way to make your trip to Mytilene relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July, with an average temperature of 25°C, while the coldest months are January and February, with an average of 11°C. Average annual precipitation for Mytilene is 873 mm.

What's there to see and do in Mytilene?

Take in the sights and attractions that Mytilene offers with a visit to Port of Mytilene, Mytilini Castle and Roman Aqueduct at Moria. If you have a little extra time during your trip, you might want to make a stop at Thermes Gera Hot Springs and St Hermogenes Charamida Lesvos.