Knowing a bit about the transportation options can save you time when you get to your destination. Fly into Cairo, IL (CIR-Cairo Regional), which is located 11.1 mi (17.9 km) from the heart of the city. Otherwise, look for flights into Paducah, KY (PAH-Barkley Regional), which is 19.6 mi (31.5 km) away. If you'd like to venture out around the area, consider renting a car to explore more sights.