A night scene with a clear sky, a crescent moon, and two silhouetted trees against a twilight sky.

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Check prices for these dates

Tonight
29 Aug - 30 Aug
Tomorrow
30 Aug - 31 Aug
Next weekend
4 Sept - 6 Sept
In two weeks
11 Sept - 13 Sept

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Our top choices for Puxico hotels

1. Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
Poplar Bluff
United States
Arsenia
Rp1.789.647
Rp2.021.853 total
includes taxes & fees
7 Sept - 8 Sept
Fairfield Inn & Suites by Marriott Poplar Bluff

2. Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
Poplar Bluff
United States
Paul
Rp1.804.509
Rp2.038.644 total
includes taxes & fees
6 Sept - 7 Sept
Drury Inn & Suites Poplar Bluff

3. Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
Poplar Bluff
United States
Kathleen
Rp1.397.747
Rp1.565.300 total
includes taxes & fees
30 Aug - 31 Aug
Motel 6 Poplar Bluff, MO

4. Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
Poplar Bluff
United States
Philip
Rp1.657.834
Rp1.856.359 total
includes taxes & fees
6 Sept - 7 Sept
Hampton Inn Poplar Bluff

5. Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
Poplar Bluff
United States
Paige
Rp1.539.291
Rp1.739.014 total
includes taxes & fees
27 Sept - 28 Sept
Holiday Inn Poplar Bluff by IHG

6. Econo Lodge Dexter

Econo Lodge Dexter
Dexter
United States
Herman
Rp902.166
Rp1.013.023 total
includes taxes & fees
28 Sept - 29 Sept
Econo Lodge Dexter

7. Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
Dexter
United States
Joyce
Rp1.726.483
Rp1.938.633 total
includes taxes & fees
7 Sept - 8 Sept
Hampton Inn By Hilton Dexter

8. Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
Dexter
United States
Steven
Rp1.630.410
Rp1.830.755 total
includes taxes & fees
13 Sept - 14 Sept
Travelodge by Wyndham Dexter

9. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
Marble Hill
United States
JANEEN
Rp1.785.046
Rp1.943.022 total
includes taxes & fees
30 Aug - 31 Aug
EC Reed's Mercantile and Hotel

10. Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri
Poplar Bluff
United States
Diana
Rp1.206.592
Rp1.363.147 total
includes taxes & fees
8 Sept - 9 Sept
Super 8 by Wyndham Poplar Bluff Missouri

11. Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North
Poplar Bluff
United States
Muhammad
Rp1.521.244
Rp1.718.626 total
includes taxes & fees
13 Sept - 14 Sept
Comfort Inn Poplar Bluff North

12. Dexter Inn

Dexter Inn
Dexter
United States
Edward
Rp1.150.045
Rp1.291.362 total
includes taxes & fees
30 Aug - 31 Aug
Dexter Inn

13. OYO Hickory House Inn

OYO Hickory House Inn
Dexter
United States
Tammy
Rp784.508
Rp959.138 total
includes taxes & fees
12 Sept - 13 Sept
OYO Hickory House Inn

14. Lake Wappapello

Lake Wappapello
Williamsville
United States
Tonya
Rp1.592.370
Rp1.679.553 total
includes taxes & fees
2 Sept - 3 Sept
Lake Wappapello
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Learn more about Puxico

Head to sights like Mark Twain National Forest and Mingo Wilderness as you discover Puxico.

See all hotels in Puxico
A night scene with a clear sky, a crescent moon, and two silhouetted trees against a twilight sky.
Photo by Mike McClain

Top Puxico Hotel Reviews

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

10/10 Excellent
"just an overall decent room vacation redy"
Elsie 2-night trip
Posted 11 hours ago
Hampton Inn Poplar Bluff
Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

10/10 Excellent
"The check-in was quick and friendly. The room was like new. Normal items for hot full breakfast. Check out was quick and friendly. Plenty of parking, easy access, and well lit."
David 1-night trip
Posted 12 hours ago
Drury Inn & Suites Poplar Bluff
Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG

10/10 Excellent
"."
Blyth 1-night trip
Posted 14 hours ago
Holiday Inn Poplar Bluff by IHG
Dexter Inn

Dexter Inn

8/10 Good
"breakfast was good, staff friendly, pool area needs work"
Edward 2-night trip
Posted 2 days ago
Dexter Inn
Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff

10/10 Excellent
"loved it!!!"
George 1-night trip
Posted 4 days ago
Fairfield Inn & Suites by Marriott Poplar Bluff
EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel

10/10 Excellent
"Great place! Room was nice and there breakfast in the mercantile was top notch!"
Drew 1-night trip
Posted 6 days ago
EC Reed's Mercantile and Hotel
Econo Lodge Dexter

Econo Lodge Dexter

10/10 Excellent
"Staff are kind, welcoming and helpful! Property is clean and well. For the pri"
Elizabeth 1-night trip
Posted 6 days ago
Econo Lodge Dexter
Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter

10/10 Excellent
"Best Hampton Inn that I have ever stayed in. Excellent service and Wonderful staff. Extremely helpful with disabled husband."
Stephen 2-night trip
Posted 9 days ago
Hampton Inn By Hilton Dexter
Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter

10/10 Excellent
"It’s was clean and very well maintained"
Larry 1-night trip
Posted 12 days ago
Travelodge by Wyndham Dexter

More cheap stays in Puxico

Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri

2831 N Westwood Blvd Poplar Bluff MO
Rp1.206.592
Rp1.363.147 total
8 Sept - 9 Sept
includes taxes & fees
Super 8 by Wyndham Poplar Bluff Missouri
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

4101 Highway 67 N Poplar Bluff MO
Rp1.397.747
Rp1.565.300 total
30 Aug - 31 Aug
includes taxes & fees
8/10 Very good! (1,000 reviews)
Motel 6 Poplar Bluff, MO
Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North

2582 N Westwood Blvd Poplar Bluff MO
Rp1.521.244
Rp1.718.626 total
13 Sept - 14 Sept
includes taxes & fees
7.8/10 Good! (436 reviews)
Comfort Inn Poplar Bluff North
Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter

1608 E Business US 60 Dexter MO
Rp1.630.410
Rp1.830.755 total
13 Sept - 14 Sept
includes taxes & fees
7.6/10 Good! (420 reviews)
Travelodge by Wyndham Dexter
Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

2420 Crestwood Dr Poplar Bluff MO
Rp1.657.834
Rp1.856.359 total
6 Sept - 7 Sept
includes taxes & fees
9.4/10 Exceptional! (924 reviews)
Hampton Inn Poplar Bluff
Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter

2179 Gill Plaza Drive Dexter MO
Rp1.726.483
Rp1.938.633 total
7 Sept - 8 Sept
includes taxes & fees
9.8/10 Exceptional! (66 reviews)
Hampton Inn By Hilton Dexter

Frequently asked questions

What's the best place for a stay in Puxico?
Motel 6 Poplar Bluff, MO, located 19.4 mi (31.3 km) from the heart of Puxico, is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Fairfield Inn & Suites by Marriott Poplar Bluff and Drury Inn & Suites Poplar Bluff. See all available top hotels, or vacation rentals in Puxico.
If I need to cancel my hotel reservation in Puxico, will I receive a refund?
Yes, you'll find most hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Puxico.
What is staying in Puxico like?
Travellers to Puxico will find plenty to explore and enjoy. There are 56 hotels and other accommodation options in the surrounding area. Find out more about Puxico.
What is there to see in Puxico?
A couple of favourite places to visit are Mark Twain National Forest and Mingo Wilderness. You'll also find Lake Wappapello and Mo-Ark Regional Railroad Museum in the area. Take a look at what more there is to see and do in Expedia's Puxico guide.
What's the seasonal weather in Puxico?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Puxico is 1502 mm.

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