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Check availability on Santee Family-Friendly Hotels

Our top choices for Santee family-friendly hotels

Property amenity
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
2.5 star property
Santee
9.8 out of 10, Exceptional, (1005)
"Spotless clean room The staff was so courteous and friendly "
United States
Amani
The price is Rp2.014.166
Rp2.235.724 total
includes taxes & fees
24 Dec - 25 Dec
Fairfield Inn & Suites by Marriott Santee
Exterior
Best Western Plus Santee Inn

Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1001)
"Nice rooms and very good breakfast items."
United States
Stephen
The price is Rp1.966.725
Rp2.183.065 total
includes taxes & fees
22 Dec - 23 Dec
Best Western Plus Santee Inn
Seasonal outdoor pool
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1004)
"Close to the highway with a safe location."
United States
Benjamin
The price is Rp1.773.631
Rp1.968.732 total
includes taxes & fees
23 Dec - 24 Dec
Comfort Inn & Suites Santee
In-room safe, iron/ironing board, free WiFi, bed sheets
Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.0 out of 10, Good, (678)
"The room was very nice. It was newly renovated and I loved the upgrade. The beds were comfortable and warm. We didn’t eat breakfast because we were meeting someone for breakfast. "
United States
Alice
The price is Rp1.015.406
Rp1.127.100 total
includes taxes & fees
5 Jan - 6 Jan 2026
Travelodge by Wyndham Santee
Desk, iron/ironing board, free WiFi, bed sheets
Econo Lodge Santee

Econo Lodge Santee

Econo Lodge Santee
2.0 star property
Santee
6.4 out of 10, (309)
"Check in was easy."
United States
Amy
The price is Rp1.052.693
Rp1.168.490 total
includes taxes & fees
7 Jan - 8 Jan 2026
Econo Lodge Santee
Free daily continental breakfast
Peach Tree Inn

Peach Tree Inn

Peach Tree Inn
2.5 star property
St. George
7.2 out of 10, Good, (137)
"Air conditioning very good, check in easy, staff very pleasant"
United States
Linda
Peach Tree Inn
Room, 2 Queen Beds, Accessible, Non Smoking (Efficiency) | Desk, iron/ironing board, free cots/infant beds, free WiFi
Comfort Inn & Suites Orangeburg

Comfort Inn & Suites Orangeburg

Comfort Inn & Suites Orangeburg
2.5 star property
Orangeburg
8.0 out of 10, Very good, (551)
"Would recommend this hotel for out of town guest with no hesitation. "
United States
Yvette
The price is Rp1.581.204
Rp1.755.136 total
includes taxes & fees
21 Dec - 22 Dec
Comfort Inn & Suites Orangeburg
Exterior
Holiday Inn Express & Suites Orangeburg by IHG

Holiday Inn Express & Suites Orangeburg by IHG

Holiday Inn Express & Suites Orangeburg by IHG
2.5 star property
Orangeburg
8.6 out of 10, Excellent, (793)
"The room was spotless and the staff was courteous. "
United States
Terrance
The price is Rp1.897.644
Rp2.106.384 total
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Express & Suites Orangeburg by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santee Hotel Reviews

Frequently asked questions

What's Santee like for family-friendly holidays?
The welcoming destination of Santee is a great choice if you've been thinking about a holiday with the children. The excursions, lake views and golf are just a few things that make this an attractive holiday destination for families. Arrange a flight into Columbia, SC (CAE-Columbia Metropolitan), which is located 49 mi (78.8 km) from the city centre.
What's the best family accommodation in Santee?
Fairfield Inn & Suites by Marriott Santee is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Comfort Inn & Suites Santee is another good option for your family trip.
When's the best time to book a family-friendly holiday in Santee?
The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 11°C. Average annual precipitation for Santee is 1397 mm.
What's there to see and do with your family in Santee?
While you and your family are visiting Santee, you may want to explore some child-friendly attractions such as Santee Indian Mound and Fort Watson Site and Orangeburg County Library Mentor Branch. Make sure that you have lots of time for activities such as Lake Marion and Santee National Wildlife Refuge.