A historic stone building with intricate architecture, a well-maintained lawn, and a sidewalk.

Central West End Hotel Guide - 4 Stars Hotels in Central West End, St. Louis

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Check availability on Central West End 4 Star Hotels

Our top choices for Central West End 4-star hotels

A lobby with a sofa, two armchairs, a coffee table, and a staircase.

1. Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (4,407 reviews)
"Great location and great place to visit"
United States
Tracy
The price is Rp2.035.012
Rp2.399.870 total
includes taxes & fees
27 Nov - 28 Nov
Hyatt Regency St. Louis at The Arch
A bar area with high wooden ceilings, a large mural, and a variety of seating options including tables and bar stools.

2. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (2,148 reviews)
"Wonderful Stay!"
United States
A.R.
The price is Rp2.598.091
Rp3.128.347 total
includes taxes & fees
7 Dec - 8 Dec
21C Museum Hotel St Louis
A buffet with fruits, pastries, and beverages.

3. Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
Berkeley
8.4 out of 10, Very good, (1,200 reviews)
"Great Hotel."
United States
Joy
The price is Rp2.011.052
Rp2.352.689 total
includes taxes & fees
27 Nov - 28 Nov
Renaissance St. Louis Airport Hotel
A rooftop restaurant with round tables, chairs, and a view of the city.

4. Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (2,059 reviews)
"Cool hotel!"
United States
Rebecca
The price is Rp2.519.240
Rp2.996.106 total
includes taxes & fees
24 Nov - 25 Nov
Moonrise Hotel
The exterior of the Clark & Bourbon hotel with a well-lit entrance, a marquee sign, and a landscaped planter area.

5. Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,366 reviews)
"Great place to stay."
United States
brandon
The price is Rp2.513.815
Rp2.989.631 total
includes taxes & fees
15 Nov - 16 Nov
Live by Loews - St.Louis
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.

6. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,094 reviews)
"Very nice hotel, lots of amenities, and restaurants"
United States
Carter
The price is Rp2.879.769
Rp3.665.696 total
includes taxes & fees
23 Nov - 24 Nov
Ameristar Casino Resort and Spa
A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.

7. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End
9.2 out of 10, Wonderful, (1,008 reviews)
"The hotel is beautiful, and we really enjoyed the restaurants--The Tenderloin Room was especially delicious!"
United States
Sara
The price is Rp2.694.665
Rp3.710.937 total
includes taxes & fees
22 Nov - 23 Nov
The Royal Sonesta Chase Park Plaza St. Louis
A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a modern building with large windows.

8. Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
Clayton
8.8 out of 10, Excellent, (802 reviews)
"Beautiful hotel in a convenient location."
United States
Marsha
The price is Rp2.751.633
Rp3.239.719 total
includes taxes & fees
22 Nov - 23 Nov
Le Méridien St. Louis Clayton
A modern hotel room with a large bed, a nightstand, a mirror, and a view of the city through arched windows.

9. The Westin St. Louis

The Westin St. Louis
4.5 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,004 reviews)
"Amazing property, staff was very friendly, great location!!"
United States
Stacy
The price is Rp2.212.157
Rp2.586.653 total
includes taxes & fees
22 Nov - 23 Nov
The Westin St. Louis
A modern dining area with round tables, orange chairs, and a decorative wall with pottery.

10. Marriott St. Louis Airport

Marriott St. Louis Airport
4.0 star property
Edmundson
8.0 out of 10, Very good, (1,004 reviews)
"Was a great stay"
United States
Loney
The price is Rp2.578.921
Rp3.103.422 total
includes taxes & fees
27 Nov - 28 Nov
Marriott St. Louis Airport
A long bar with multiple tables and chairs, wooden floors, and ornate chandeliers.

11. River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1,843 reviews)
"Great accommodations - highly recommend"
United States
jodi
The price is Rp1.507.425
Rp2.031.980 total
includes taxes & fees
18 Nov - 19 Nov
River City Casino & Hotel
A multi-story hotel with a prominent 'Marriott' sign, featuring a classic architectural style with a red brick facade and large windows.

12. Marriott St. Louis Grand

Marriott St. Louis Grand
4.0 star property
Downtown St. Louis
8.4 out of 10, Very good, (1,007 reviews)
"The nicest room for the best price at this location. We stay in St Louis once per year and this was the best room! Love the proximity to the dome, and riverfront as well as nice restaurants"
United States
MARY BETH
The price is Rp2.296.795
Rp2.731.555 total
includes taxes & fees
22 Nov - 23 Nov
Marriott St. Louis Grand
A bar area with a central bar, multiple stools, and a chandelier.

13. Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (1,410 reviews)
"Gorgeous historic hotel close to all main downtown sightseeings."
United States
Anastasia
The price is Rp1.718.455
Rp2.043.740 total
includes taxes & fees
23 Nov - 24 Nov
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

14. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
Brentwood
9.6 out of 10, Exceptional, (1,011 reviews)
"Really enjoyed the breakfast and happy hours!"
United States
Stacey Rochelle
The price is Rp2.314.699
Rp2.749.153 total
includes taxes & fees
22 Nov - 23 Nov
Drury Plaza Hotel St. Louis Brentwood
A cozy lounge area with leather sofas, a fireplace, and a bar counter.

15. The Cheshire

The Cheshire
4.0 star property
Richmond Heights
8.8 out of 10, Excellent, (1,008 reviews)
"Fantastic hotel, clean and nice rooms, great breakfast and location"
United States
Matthew
The price is Rp2.695.388
Rp3.200.449 total
includes taxes & fees
29 Nov - 30 Nov
The Cheshire
A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.

16. Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis
9.0 out of 10, Wonderful, (1,371 reviews)
"Loved our stay!"
United States
Megan
The price is Rp1.906.581
Rp2.267.476 total
includes taxes & fees
10 Dec - 11 Dec
Embassy Suites by Hilton St. Louis Downtown
A rooftop terrace with outdoor seating, string lights, and a city skyline view.

17. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
Grand Center
8.8 out of 10, Excellent, (1,175 reviews)
"Loved the hotel!"
United States
Stephanie
The price is Rp1.868.904
Rp2.204.200 total
includes taxes & fees
22 Nov - 23 Nov
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
A modern lounge area with a central fire feature, seating, and large windows offering a city view.

18. Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark
4.0 star property
Downtown St. Louis
7.6 out of 10, Good, (1,291 reviews)
"AMAZING STAY! AMAZING VIEWS FEOM ROOFTOP BAR!"
United States
Kella
The price is Rp2.506.219
Rp2.980.622 total
includes taxes & fees
22 Nov - 23 Nov
Hilton St. Louis at the Ballpark
A spacious lobby with high arched ceilings, ornate columns, and a central fountain.

19. St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West
8.8 out of 10, Excellent, (1,004 reviews)
"Front desk staff was very helpful in answering question about the property and surrounding area!"
United States
William
The price is Rp2.802.596
Rp3.333.136 total
includes taxes & fees
23 Nov - 24 Nov
St. Louis Union Station Hotel, Curio Collection by Hilton
A spacious lobby with modern seating arrangements, a large chandelier, and a view of the cityscape through large windows.

20. Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,155 reviews)
"I enjoyed my stay and parking was safe."
United States
Jacqueline
The price is Rp1.983.020
Rp2.318.725 total
includes taxes & fees
22 Nov - 23 Nov
Hilton Pennywell St. Louis at the Arch
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Central West End.
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO
The price is Rp6.781.875 per night from 12 Nov to 13 Nov
Rp6.781.875
Rp7.929.979 total
12 Nov - 13 Nov
includes taxes & fees
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

See all hotels in Central West End
A historic building with a green dome and adjacent modern high-rise buildings.

Top Central West End Hotel Reviews

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

10/10 Excellent
"L8ve the artsy feel of the property."
WENDY 1-night trip
Posted 1 day ago
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

10/10 Excellent
"My family has been staying here for years. They are doing a wonderful job with keeping up with the times. Great clean rooms and a wonderful staff. Please keep up the good work."
jarrett 2-night trip
Posted 2 days ago
Renaissance St. Louis Airport Hotel

Frequently asked questions

What are the best 4-star hotels in Central West End?
AC Hotel St. Louis Central West End and DoubleTree by Hilton St. Louis Forest Park are two highly recommended getaways situated around Central West End. Both have a 4-star rating and promise high-end comfort alongside an unbeatable guest experience. Check in to the first and get access to fitness facilities and free WiFi. The second features windsurfing and a bar, among many amenities.
How much does it cost to stay in a 4-star hotel in Central West End?
With Expedia's filter tool, locking in a superb deal on a 4-star hotel in Central West End just got simpler. Start by entering your chosen travel dates and length of your stay. Then sort the results by price and choose a hotel that best fits your style and budget.

  • Search for the lowest price from Rp7.929.979

What's the difference between 5-star and 4-star hotels in Central West End?
Offering an inviting guest experience and upmarket décor, 4-star hotels are a wonderful option for your Central West End holiday. These kinds of stays generally come with loads of useful amenities that make it easy to unpack and unwind — think pillowtop mattresses, pools and gyms. Or get a taste of the high life at a 5-star hotel designed to pamper with exclusive perks and amenities. On-site health clubs, premium toiletries and world-class dining are typically included at these plush retreats.