The Best Hotels Closest to Don and Sybil Harrington Cancer Center in Amarillo - 2026 Updated Prices

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Our top choices for Don and Sybil Harrington Cancer Center hotels

A modern room with a sofa, a chair, a lamp, and a television.

A modern hotel dining area with multiple tables and chairs, a large TV screen, and a central pillar with a geometric design.

A Holiday Inn Express building with a modern design, featuring a prominent entrance and a covered outdoor area.

A modern lobby with seating areas, a reception desk, and a decorative tree centerpiece.

1. Holiday Inn Express & Suites Amarillo West by IHG

1.4 km from Don and Sybil Harrington Cancer Center

Jack

Rp1.673.045

Rp1.924.002 total

includes taxes & fees

11 Oct - 12 Oct

A spacious lobby with a modern design, featuring a seating area with colorful cushions, a large chandelier, and a flat-screen TV mounted on the wall.

An indoor swimming pool with clear water, a tiled floor, and a ceiling with recessed lighting.

A vending area with snack and drink options, including a refrigerated section with beverages and a shelf stocked with various snacks.

2. Best Western Plus Medical Center

0.4 km from Don and Sybil Harrington Cancer Center

Elizabeth

Rp1.781.353

Rp2.048.557 total

includes taxes & fees

20 Sept - 21 Sept

A spacious restaurant with high ceilings, stone walls, and large windows.

A living room with a stone fireplace, a sofa set, and a patterned rug.

A hotel room with two beds, each with a headboard, bedside lamps, and a patterned throw blanket.

A multi-story hotel with a prominent entrance, multiple balconies, and a clear blue sky.

3. Drury Inn & Suites Amarillo

1.9 km from Don and Sybil Harrington Cancer Center

Randall

Rp1.901.812

Rp2.187.083 total

includes taxes & fees

4 Oct - 5 Oct

An outdoor patio with a fire feature, seating, and a grill area.

A hotel hallway with a patterned carpet, white doors, and recessed lighting.

A modern kitchen with a central island, a red waffle sign, and a coffee station.

An indoor swimming pool with clear blue walls and large windows, surrounded by seating areas and a view of the outside.

4. Hampton Inn & Suites Amarillo West

1.7 km from Don and Sybil Harrington Cancer Center

Miguel

Rp1.784.523

Rp2.052.203 total

includes taxes & fees

4 Oct - 5 Oct

A modern lounge area with seating, tables, and a kitchen area.

A pool table in a room with a mural, seating, and a large window.

A modern food service area with a central counter, a refrigerated display, and various food items.

5. Tru By Hilton Amarillo West

2.1 km from Don and Sybil Harrington Cancer Center

Diane

Rp1.470.258

Rp1.702.558 total

includes taxes & fees

27 Sept - 28 Sept

A multi-story hotel with a modern design, featuring a prominent entrance and a parking lot.

An indoor swimming pool with lounge chairs and a view of the night sky through large windows.

A modern hotel lobby with a dining area, a reception desk, and a seating area with a coffee table.

A hotel room with two beds, a desk, a TV, and a bathroom door.

6. Hyatt Place Amarillo-West

2.2 km from Don and Sybil Harrington Cancer Center

Michal

Rp1.919.599

Rp2.245.931 total

includes taxes & fees

27 Sept - 28 Sept

An outdoor seating area with a fire pit, lounge chairs, and a building with large windows and a covered patio.

A modern hotel room with a kitchenette, a bed, a desk, and a large window.

A multi-story hotel with a modern design, featuring a prominent entrance with outdoor seating and a covered area.

A modern hotel lobby with a central seating area, a dining table, and a TV screen.

7. TownePlace Suites by Marriott Amarillo West/Medical Center

1.2 km from Don and Sybil Harrington Cancer Center

angela

Rp2.976.259

Rp3.422.698 total

includes taxes & fees

20 Sept - 21 Sept

An outdoor seating area with stone flooring, cushioned benches, and green chairs.

A hotel room with a bed, desk, and seating area.

A modern hotel with a covered entrance, multiple floors, and a sign reading "Springhill Suites Marriott".

A modern bar area with seating, a bar counter, and a television mounted on the ceiling.

8. Springhill Suites by Marriott Amarillo

1.6 km from Don and Sybil Harrington Cancer Center

Michael

Rp2.154.178

Rp2.477.304 total

includes taxes & fees

27 Sept - 28 Sept

An outdoor patio with a stone fireplace, a grill, and a dining area with chairs and tables.

A spacious lobby with a fireplace, seating area, reception desk, and a modern kitchen in the background.

A hotel with a modern design, featuring a covered entrance, outdoor seating, and a well-maintained landscape.

A hotel lobby with a reception desk, seating area, and a large window with a view.

9. Homewood Suites by Hilton Amarillo

2.2 km from Don and Sybil Harrington Cancer Center

todd

Rp1.571.958

Rp1.807.751 total

includes taxes & fees

4 Oct - 5 Oct

A hotel room with two beds, a TV, a window with blinds, a framed picture on the wall, and a bedside lamp.

A multi-story hotel with a prominent 'My Place' sign, a parking lot, and a well-lit facade.

10. My Place Hotel - Amarillo West/ Medical Center, TX

1.6 km from Don and Sybil Harrington Cancer Center

justin

Rp1.410.641

Rp1.622.238 total

includes taxes & fees

20 Sept - 21 Sept

An outdoor seating area with wicker chairs and a fire pit.

A hotel room with a bed, a sofa, a desk, and a television.

A sign instructing to clean up after dogs and dispose of waste, with a trash can nearby.

A multi-story hotel with a prominent 'Home2' sign, a covered entrance, and a parking lot.

11. Home2 Suites by Hilton Amarillo

1.3 km from Don and Sybil Harrington Cancer Center

Amanda

Rp2.085.671

Rp2.398.522 total

includes taxes & fees

27 Sept - 28 Sept

A swimming pool with clear water, a brick deck, and a waterfall feature.

A hotel room with a desk, office chair, striped armchair, red sofa, ottoman, and a television.

A traditional living room with leather sofas, a fireplace, and a clock on the wall.

A hotel breakfast area with a self-service station, coffee makers, and various food containers.

12. Country Inn & Suites by Radisson, Amarillo I-40 West, TX

2 km from Don and Sybil Harrington Cancer Center

Karen

Rp1.430.013

Rp1.644.515 total

includes taxes & fees

4 Oct - 5 Oct

A lobby with a reception desk, seating area, and a stone wall with framed pictures.

A hotel room with a sofa, a bed, a desk, and a television.

A living room with a sofa, armchair, ottoman, coffee table, TV, and artwork on the walls.

13. Comfort Inn & Suites Amarillo West Near Medical Center

2.2 km from Don and Sybil Harrington Cancer Center

Shawn

Rp1.534.270

Rp1.764.410 total

includes taxes & fees

4 Oct - 5 Oct

A hotel lobby with a blue sofa, a fireplace, a dining area, and a TV mounted on the wall.

A reception desk with a wooden finish, a black countertop, and a blue illuminated wall feature.

An indoor swimming pool with tiled flooring, yellow lounge chairs, and a ceiling with recessed lighting.

A modern living room with a fireplace, a blue sectional sofa, and a flat-screen TV mounted on the wall.

14. Fairfield Inn & Suites Amarillo West/Medical Center

1 km from Don and Sybil Harrington Cancer Center

Tania

Rp1.648.390

Rp1.933.512 total

includes taxes & fees

4 Oct - 5 Oct

A hotel lobby with a high ceiling, a fireplace, a flat-screen TV, and a large abstract painting on the wall.

An outdoor patio area with tables and chairs, blue umbrellas, and a building labeled "Residence Inn" in the background.

A hotel room with a large bed, two bedside lamps, a wooden headboard, a nightstand, and a vase with flowers.

A hotel room with a dining area, a fireplace, a TV, and a bed.

15. Yellow City Studios

1 km from Don and Sybil Harrington Cancer Center

Ayvan

Rp1.014.394

Rp1.166.553 total

includes taxes & fees

22 Sept - 23 Sept

A modern living room with a blue sofa, wooden flooring, and framed pictures on the walls.

A modern hotel with multiple floors, a parking lot, and a well-lit entrance.

A modern dining area with a wooden table and chairs, a television on a wall, and a view of the outside.

A hotel room with a bed, a desk with a computer, a chair, a sofa, and a large mirror.

16. Everhome Suites Amarillo West - Medical Center

1.2 km from Don and Sybil Harrington Cancer Center

Mohammad

Rp2.035.832

Rp2.341.207 total

includes taxes & fees

15 Sept - 16 Sept

A spacious living area with a large sofa, a fireplace, and a patterned floor.

A hotel shop with a variety of snacks, beverages, and packaged goods.

A hotel with a large parking lot, a covered entrance, and a prominent American flag.

An indoor swimming pool with a tiled floor, ceiling fans, and a seating area with tables and chairs.

17. Hilton Garden Inn Amarillo

2.4 km from Don and Sybil Harrington Cancer Center

Gregory

Rp1.422.088

Rp1.635.401 total

includes taxes & fees

20 Sept - 21 Sept

An outdoor seating area with a fire feature, surrounded by modern buildings.

A modern bar area with a wooden counter, bar stools, a refrigerator stocked with beverages, and a menu board.

A modern kitchen with a bar area, a round dining table, and a sofa.

A modern living room with a stone wall, a fireplace, and a large sectional sofa.

18. Courtyard by Marriott Amarillo West/Medical Center

1.4 km from Don and Sybil Harrington Cancer Center

Ronnie

Rp2.005.893

Rp2.318.929 total

includes taxes & fees

20 Sept - 21 Sept

A spacious indoor area with wooden flooring, multiple seating arrangements including sofas and tables, and large windows allowing natural light.

A modern interior with a yellow counter, coffee machines, and a rocking chair.

A modern interior with a green carpet, wooden flooring, and a wall with a geometric design.

A reception desk with a wooden finish, a modern abstract painting, and a decorative lamp.

19. Spark by Hilton Amarillo Medical Center

1.1 km from Don and Sybil Harrington Cancer Center

shirley

Rp1.286.307

Rp1.479.253 total

includes taxes & fees

12 Oct - 13 Oct

A hotel entrance with a glass door, stone pillars, and a clear view of the parking lot.

A pool area with two pools, one rectangular and one octagonal, with depth markers and a diving sign.

A buffet setup with multiple serving stations, including a toaster and a grill, against a tiled backsplash.

A hotel reception area with a reception desk, a large mirror, and a patterned floor.

20. Sleep Inn & Suites West Medical Center

1.1 km from Don and Sybil Harrington Cancer Center

CRIS

Rp1.331.392

Rp1.531.101 total

includes taxes & fees

21 Sept - 22 Sept

View all properties

Compare popular hotels close to Don and Sybil Harrington Cancer Center

Property	Property class	Guest rating
Holiday Inn Express & Suites Amarillo West by IHG	9.4 Exceptional 2,286 reviews	View
Best Western Plus Medical Center	9.4 Exceptional 1,928 reviews	View
Drury Inn & Suites Amarillo	9.4 Exceptional 2,459 reviews	View
Hampton Inn & Suites Amarillo West	9.4 Exceptional 513 reviews	View
Tru By Hilton Amarillo West	9.2 Wonderful 1,281 reviews	View

Top Don and Sybil Harrington Cancer Center Hotel Reviews

Country Inn & Suites by Radisson, Amarillo I-40 West, TX

8/10 Good

"Nice hotel although a bit dated but definitely a country feel"

Atrea Inn Amarillo

10/10 Excellent

"Was a definite upgrade from the place I initially booked in Amarillo."

Spark by Hilton Amarillo Medical Center

10/10 Excellent

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Comfort Inn & Suites Amarillo West Near Medical Center

8/10 Good

"Staff very nice. Large room. Clean but It was supposed to be Non Smoking room and it smelled of smoke . We didn’t complain because it was around 10:00 pm. and we were checking out out early to get back on the road. Breakfast was very good."

Spark by Hilton Amarillo Western Plaza

8/10 Good

"Staff member that checked us in was very nice. Not a good breakfast and server did not greet us back or have a smile. Shower water flow was very low. Only one roll of toilet paper and it was very thin paper. Staff member that checked us out was very friendly."

Drury Inn & Suites Amarillo

10/10 Excellent

"Waiting staff was super friendly rooms very clean"

Quality Inn Amarillo West near Medical Center

8/10 Good

"Parking was very convenient and room was comfortable"

Red Roof Inn Amarillo West

10/10 Excellent

"I drive from CO to TX regularly and have stayed at a lot of road-side hotels on the route. I usually travel with dogs and bikes, which require a large, pet friendly room. This was the largest and nicest room, in the value space, with a reasonable pet-fee, that I've stayed at in several years, and will become my spot to-stop on the route moving forward. The only thing that could use improvement, was the coffee/breakfast situation - but again, what was there was serviceable. We look forward to staying there again in the future!"

Frequently asked questions

What's the area like around Don and Sybil Harrington Cancer Center?

Don and Sybil Harrington Cancer Center is located in a family-friendly area of Amarillo known for its array of dining options and sporting events. If you're looking for a convenient place to stay, take a look at the 44 hotels and other accommodation options you'll find within a mile.

What's the best place to stay near Don and Sybil Harrington Cancer Center?

Adjacent to Don and Sybil Harrington Cancer Center, Best Western Plus Medical Center is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. Other good options within a short distance include Holiday Inn Express & Suites Amarillo West by IHG and Fifth Season Suites.

How many hotels should I expect to find near Don and Sybil Harrington Cancer Center?

Expedia has 44 hotels and other accommodation options within a mile from Don and Sybil Harrington Cancer Center.

If I need to cancel the hotel reservation for my stay near Don and Sybil Harrington Cancer Center, will I receive a refund?

Yes, you'll find most hotel room reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you have a reservation that's non-refundable, you may still be able to cancel and get a refund within 24 hours of booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to get the best deals near Don and Sybil Harrington Cancer Center.

What can I see and do near Don and Sybil Harrington Cancer Center?

Amarillo Museum of Art, Don Harrington Discovery Center and Amarillo Art Center feature captivating exhibits. Learn about local history at Historic 6th Street Sign and Harrington House. You can enjoy live performances at Amarillo Little Theatre and Globe-News Center.

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Our top choices for Don and Sybil Harrington Cancer Center hotels

1. Holiday Inn Express & Suites Amarillo West by IHG

2. Best Western Plus Medical Center

3. Drury Inn & Suites Amarillo

4. Hampton Inn & Suites Amarillo West

5. Tru By Hilton Amarillo West

6. Hyatt Place Amarillo-West

7. TownePlace Suites by Marriott Amarillo West/Medical Center

8. Springhill Suites by Marriott Amarillo

9. Homewood Suites by Hilton Amarillo

10. My Place Hotel - Amarillo West/ Medical Center, TX

11. Home2 Suites by Hilton Amarillo

12. Country Inn & Suites by Radisson, Amarillo I-40 West, TX

13. Comfort Inn & Suites Amarillo West Near Medical Center

14. Fairfield Inn & Suites Amarillo West/Medical Center

15. Yellow City Studios

16. Everhome Suites Amarillo West - Medical Center

17. Hilton Garden Inn Amarillo

18. Courtyard by Marriott Amarillo West/Medical Center

19. Spark by Hilton Amarillo Medical Center

20. Sleep Inn & Suites West Medical Center

Compare popular hotels close to Don and Sybil Harrington Cancer Center

Top Don and Sybil Harrington Cancer Center Hotel Reviews

Country Inn & Suites by Radisson, Amarillo I-40 West, TX

Atrea Inn Amarillo

Spark by Hilton Amarillo Medical Center

Comfort Inn & Suites Amarillo West Near Medical Center

Spark by Hilton Amarillo Western Plaza

Drury Inn & Suites Amarillo

Quality Inn Amarillo West near Medical Center

Red Roof Inn Amarillo West

Frequently asked questions

Search Hotels Near Don and Sybil Harrington Cancer Center, Amarillo

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Don and Sybil Harrington Cancer Center hotels

1. Holiday Inn Express & Suites Amarillo West by IHG

2. Best Western Plus Medical Center

3. Drury Inn & Suites Amarillo

4. Hampton Inn & Suites Amarillo West

5. Tru By Hilton Amarillo West

6. Hyatt Place Amarillo-West

7. TownePlace Suites by Marriott Amarillo West/Medical Center

8. Springhill Suites by Marriott Amarillo

9. Homewood Suites by Hilton Amarillo

10. My Place Hotel - Amarillo West/ Medical Center, TX

11. Home2 Suites by Hilton Amarillo

12. Country Inn & Suites by Radisson, Amarillo I-40 West, TX

13. Comfort Inn & Suites Amarillo West Near Medical Center

14. Fairfield Inn & Suites Amarillo West/Medical Center

15. Yellow City Studios

16. Everhome Suites Amarillo West - Medical Center

17. Hilton Garden Inn Amarillo

18. Courtyard by Marriott Amarillo West/Medical Center

19. Spark by Hilton Amarillo Medical Center

20. Sleep Inn & Suites West Medical Center

Compare popular hotels close to Don and Sybil Harrington Cancer Center

Top Don and Sybil Harrington Cancer Center Hotel Reviews

Country Inn & Suites by Radisson, Amarillo I-40 West, TX

Atrea Inn Amarillo

Spark by Hilton Amarillo Medical Center

Comfort Inn & Suites Amarillo West Near Medical Center

Spark by Hilton Amarillo Western Plaza

Drury Inn & Suites Amarillo

Quality Inn Amarillo West near Medical Center

Red Roof Inn Amarillo West

Frequently asked questions