Find hotels in East Prairie, MO from Rp1.047.989

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Our top choices for East Prairie hotels

Front of property – evening/night
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, (616)
This Charleston motel offers complimentary on-the-go breakfast and WiFi for a hassle-free stay. Guests appreciate the helpful staff and free parking. Located within driving distance of Cape Girardeau Municipal Airport for easy regional access.
"Staff was great! Room was nice. "
United States
Lana
The price is Rp1.038.622
Rp1.152.611 total
includes taxes & fees
6 Jan - 7 Jan
Super 8 by Wyndham Charleston/Sikeston East MO
Property amenity
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1005)
Located just off the highway near Sikeston dining and shopping, this hotel offers both indoor and outdoor pools for year-round swimming. Guests praise the peaceful atmosphere, helpful staff, and complimentary breakfast, parking, and WiFi.
"Great place. Friendly staff clean"
United States
Jeff
The price is Rp1.505.083
Rp1.730.369 total
includes taxes & fees
11 Jan - 12 Jan
Drury Inn & Suites Sikeston, MO
Seasonal outdoor pool
Hospitality House Union City I 69 / US 51

Hospitality House Union City I 69 / US 51

Hospitality House Union City I 69 / US 51
2.5 star property
Union City
6.8 out of 10, (372)
Business travellers love this Union City hotel with a seasonal outdoor pool and on-site restaurant. Enjoy complimentary breakfast, WiFi, and parking. The helpful staff receives excellent reviews, and nearby County Market Place and Reelfoot Shopping Centre offer local attractions.
"Very friendly staff. Upgraded my room to accommodate my first floor request. Room was clean and very comfortable. I would definitely stay here again. "
United States
Barb
The price is Rp910.007
Rp1.080.770 total
includes taxes & fees
2 Feb - 3 Feb
Hospitality House Union City I 69 / US 51
Lobby
Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America
2.5 star property
Union City
9.2 out of 10, Wonderful, (326)
Located in Union City, this hotel offers convenient access to Discovery Park of America. Enjoy free breakfast, WiFi, and parking. Jump into the indoor pool or get active in the 24-hour fitness centre, making your Tennessee adventure complete.
"The rooms are big and the property is spotless!"
United States
debbie
The price is Rp1.339.673
Rp1.590.862 total
includes taxes & fees
11 Jan - 12 Jan
Sleep Inn at Discovery Park of America
Lobby
Quality Inn Union City US 51

Quality Inn Union City US 51

Quality Inn Union City US 51
2.5 star property
Union City
8.4 out of 10, Very good, (489)
Unwind at this Union City hotel offering a seasonal outdoor pool and hot tub for relaxation. Just a short distance from County Market Place and Reelfoot Shopping Centre, guests enjoy free breakfast, WiFi, and parking.
"Nice room"
Mexico
José Ricardo
The price is Rp1.123.084
Rp1.333.663 total
includes taxes & fees
1 Feb - 2 Feb
Quality Inn Union City US 51
Free daily buffet breakfast
Holiday Inn Express & Suites Union City by IHG

Holiday Inn Express & Suites Union City by IHG

Holiday Inn Express & Suites Union City by IHG
2.5 star property
Union City
9.4 out of 10, Exceptional, (310)
Experience comfort in the entertainment district of Union City at this welcoming hotel. Start your day with free breakfast before exploring nearby Discovery Park of America. After sightseeing, unwind in the indoor pool or maintain your routine at the 24-hour fitness centre.
"Rooms were spotless and comfortable. The bathroom had all the amenities. Great view. Awesome buffet breakfast to wake up to. "
United States
Rickey Smith
The price is Rp1.521.975
Rp1.807.346 total
includes taxes & fees
15 Jan - 16 Jan
Holiday Inn Express & Suites Union City by IHG
Free daily full breakfast
Best Western Plus Sikeston

Best Western Plus Sikeston

Best Western Plus Sikeston
2.5 star property
Sikeston
8.4 out of 10, Very good, (1007)
Located in Sikeston, this hotel offers an indoor pool for relaxing swims after a day of exploring. Near Central Park and the Sikeston Depot Museum, guests praise the delicious free breakfast and attentive service.
"Great stay, everything was clean and comfortable. "
United States
Charles
The price is Rp1.321.944
Rp1.506.686 total
includes taxes & fees
9 Jan - 10 Jan
Best Western Plus Sikeston
Reception
Country Hearth Inn & Suites Union City

Country Hearth Inn & Suites Union City

Country Hearth Inn & Suites Union City
2.5 star property
Union City
8.6 out of 10, Excellent, (550)
Discover convenience at this friendly Union City motel, where free breakfast and parking enhance every stay. Explore County Market Place and Reelfoot Shopping Centre nearby. Guests consistently praise the clean rooms and helpful staff.
"Roaches!"
United States
Teresa
The price is Rp1.324.453
Rp1.572.819 total
includes taxes & fees
8 Jan - 9 Jan
Country Hearth Inn & Suites Union City
Exterior
Hampton Inn Sikeston

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (456)
Take a refreshing dip in the indoor pool or maintain your routine at the fitness centre. Free breakfast, WiFi, and parking enhance your stay. Central Park and Sikeston Depot Museum are just moments away from this welcoming retreat.
"Very clean and super friendly staff!"
United States
Katherine
The price is Rp1.686.215
Rp1.909.217 total
includes taxes & fees
11 Jan - 12 Jan
Hampton Inn Sikeston
Desk, iron/ironing board, free WiFi, alarm clocks
Eagle Inn Charleston

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (105)
Discover relaxation at this Charleston motel offering complimentary WiFi and parking. The on-site health club provides fitness options after exploring local attractions. Cape Girardeau Municipal Airport is just a 43-minute drive away.
"Middle of nowhere hotel was ok"
United States
David
The price is Rp1.011.695
Rp1.122.749 total
includes taxes & fees
6 Jan - 7 Jan
Eagle Inn Charleston
Premier Room, 1 Bedroom, Non Smoking | Desk, free WiFi, bed sheets
New Orleans Inn Portageville

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very good, (733)
This welcoming motel offers clean rooms praised by guests, plus convenient amenities including free WiFi and parking. The 24-hour front desk ensures assistance anytime during your stay in charming Portageville.
"Friendly sta"
United States
Melissa
New Orleans Inn Portageville
1 bedroom, desk, laptop workspace, blackout curtains
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.2 out of 10, Good, (1003)
This tranquil Sikeston hotel offers complimentary on-the-go breakfast and WiFi, plus convenient access to Central Park and Sikeston Depot Museum. Guests appreciate the helpful staff, clean rooms, and free parking, with a fitness centre for morning workouts.
"A great stay in every aspect. "
United States
Gertrude
The price is Rp1.052.003
Rp1.199.020 total
includes taxes & fees
11 Jan - 12 Jan
Days Inn and Suites by Wyndham Sikeston
Room, 1 King Bed, Accessible, Non Smoking | Desk, laptop workspace, blackout curtains, free WiFi
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
Sikeston
6.8 out of 10, (577)
Start your day with complimentary breakfast at this Sikeston hotel. Enjoy free WiFi and parking while staying minutes from Central Park and the Sikeston Depot Museum. Cape Girardeau Municipal Airport is just a 29-minute drive away.
"Great place"
United States
Misty
The price is Rp993.465
Rp1.132.450 total
includes taxes & fees
6 Jan - 7 Jan
Super 8 by Wyndham Sikeston/Miner Area
Exterior
Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (283)
Experience refreshing comfort at this Sikeston hotel with an indoor swimming pool and fitness centre. Near Central Park and Sikeston Depot Museum, travellers appreciate the helpful staff, complimentary WiFi, and free parking for a convenient, stress-free stay.
"The hotel was very clean, beds were comfortable, and staff was friendly and helpful."
United States
aileen
The price is Rp1.478.490
Rp1.685.111 total
includes taxes & fees
11 Jan - 12 Jan
Comfort Inn & Suites Sikeston I-55
Suite, 2 Queen Beds, Non Smoking | Individually furnished, desk, laptop workspace, blackout curtains
MainStay Suites Union City, TN

MainStay Suites Union City, TN

MainStay Suites Union City, TN
2.5 star property
Union City
8.6 out of 10, Excellent, (42)
Hiking trails surround this welcoming hotel with free breakfast and parking. The 24-hour fitness centre and health club keep exercise routines on track, while in-room refrigerators and microwaves add convenience for extended stays.
"Very clean room, friendly staff! I would highly recommend this place! "
United States
Lydia
The price is Rp1.414.935
Rp1.680.235 total
includes taxes & fees
11 Jan - 12 Jan
MainStay Suites Union City, TN
Exterior
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (445)
Discover comfort at this Sikeston hotel with an indoor pool and fitness centre. Enjoy complimentary breakfast, WiFi, and parking while exploring nearby Central Park and Sikeston Depot Museum. Guests consistently praise the helpful staff and immaculate rooms.
"Stay was excellent "
United States
Kourtney
The price is Rp1.555.425
Rp1.761.130 total
includes taxes & fees
11 Jan - 12 Jan
Holiday Inn Express & Suites Sikeston Southwest by IHG
Exterior
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very good, (727)
Enjoy tranquil accommodation at this welcoming Sikeston hotel where helpful staff receive consistent praise. Located near Central Park and Sikeston Depot Museum, guests appreciate the quiet atmosphere, clean rooms, and daily continental breakfast.
"Clean room and easy access to room"
United States
Anne
The price is Rp928.070
Rp1.057.768 total
includes taxes & fees
6 Jan - 7 Jan
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Handicap Room | Blackout curtains, iron/ironing board, free WiFi, bed sheets
Reelfoot Lake Inn

Reelfoot Lake Inn

Reelfoot Lake Inn
2.0 star property
Tiptonville
7.2 out of 10, Good, (463)
"I had a decent stay near Reelfoot Lake — definitely about a 2-star hotel. I appreciated that the room had tile floors instead of carpet, though they weren’t very clean or well-kept. The door barely locked, which was a bit concerning, and there were dogs barking throughout the night, making it hard to rest. That said, I was thankful to find a place at the last minute, and it served its purpose for a quick overnight stay."
United States
Allison
The price is Rp1.020.225
Rp1.170.708 total
includes taxes & fees
29 Jan - 30 Jan
Reelfoot Lake Inn
Terrace/patio
Hampton Inn Union City

Hampton Inn Union City

Hampton Inn Union City
2.5 star property
Union City
9.6 out of 10, Exceptional, (166)
Located near County Market Place and Reelfoot Shopping Centre, this welcoming hotel offers a free breakfast and convenient parking. Take a morning swim in the indoor pool after enjoying the complimentary meal. The helpful staff earns consistent praise from guests.
"Clean room, nice breakfast"
United States
STUART
The price is Rp1.714.313
Rp2.035.747 total
includes taxes & fees
11 Jan - 12 Jan
Hampton Inn Union City
Bar (on property)
Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
2.5 star property
Sikeston
9.2 out of 10, Wonderful, (47)
This business-friendly hotel offers an indoor pool, restaurant, and complimentary breakfast. Located near Sikeston Depot Museum, guests enjoy free WiFi and parking while exploring local attractions.
"THE ROOM WAS SPOTLESS, CLEAN LOBBY, WARM AND LOT OF VARITY BREAKFAST, STAFF IS SO NICE."
United States
AHMAD
The price is Rp1.833.896
Rp2.076.428 total
includes taxes & fees
11 Jan - 12 Jan
Fairfield Inn & Suites by Marriott Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular East Prairie attractions

Big Oak Tree State Park

3.8/5 (8 reviews)
You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.
See properties

Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artefacts tell the storey of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

See all hotels in East Prairie
Bridge over Mississippi River, New Orleans in background

Top East Prairie Hotel Reviews

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston

10/10 Excellent
"Rooms are clean and location is very convenient. "
Iordan 1-night trip
Posted 10 days ago
Fairfield Inn & Suites by Marriott Sikeston

More cheap stays in East Prairie

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

100 Matthews Lane Sikeston MO
The price is Rp928.070 per night from 6 Jan to 7 Jan
Rp928.070
Rp1.057.768 total
6 Jan - 7 Jan
includes taxes & fees
8.4/10 Very Good! (726 reviews)

Frequently asked questions

What's the best place for a stay in East Prairie?
Drury Inn & Suites Sikeston, MO, located 11.4 mi (18.4 km) from the heart of East Prairie, is a top choice for your stay, based on our traveller data. Other good choices for your trip to the area are Hampton Inn Sikeston and Best Western Plus Sikeston. See all available top hotels, or vacation rentals in East Prairie.
If I need to cancel my hotel reservation in East Prairie, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in East Prairie.
How is it staying in East Prairie?
Visitors will definitely enjoy all that East Prairie has to offer. There are 33 hotels and other accommodation options in the surrounding area. Find out more about East Prairie.
What are the top places to visit in East Prairie?
The picturesque setting of Big Oak Tree State Park and Mississippi River exemplify the area's natural beauty. You'll also find Sikeston Depot Museum and New Madrid Historical Museum in the area. Take a look at what more there is to see and do in Expedia's East Prairie guide.
What's the weather like in East Prairie?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for East Prairie is 1522 mm.