The Best Hotels in Epipoli, Syracuse - 2026 Updated Prices

An ancient amphitheater with stone seating and a small tower.

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Compare popular hotels in Epipoli

Property	Property class	Guest rating
B&B Kosmos	3.0 star property	9.6 Exceptional 79 reviews	View
Hotel Relax	4.0 star property	8.2 Very good 35 reviews	View
Hotel Parco delle Fontane	4.0 star property	9.2 Wonderful 313 reviews	View
Algila' Ortigia Charme Hotel	4.0 star property	9.6 Exceptional 1,001 reviews	View
Maecò Ortigia B&B	3.0 star property	10.0 Exceptional 169 reviews	View

Where to stay in Epipoli

Find the best Epipoli areas for the activities you enjoy most.

A historic waterfront with a stone bridge, illuminated buildings, and a calm water body.

Ortigia

Ortigia is popular for its seaside views, and if you're looking for more to see and do, you might think about a trip to Cathedral of Syracuse or Piazza del Duomo.

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A bridge over a turquoise waterfront with boats docked, surrounded by historic buildings.

Santa Lucia

Santa Lucia is noteworthy for its historical sites, and you can make a stop at top attractions like Porto Piccolo and Ionian Sea.

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Ancient ruins with a large amphitheater surrounded by trees.

Neapolis

While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.

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An aerial view of a coastal city with a prominent fortified structure and a densely built urban area in the background.

Grottasanta

Grottasanta is noteworthy for its historical sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

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An ancient amphitheater with stone ruins and a grassy field.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider stopping by Ionian Sea while you're exploring the neighbourhood.

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Top Epipoli Hotel Reviews

Hotel Posta

10/10 Excellent

"Super location in Ortigia, very clean, the staff is very nice and helpful."

Grand Hotel Ortigia Siracusa

10/10 Excellent

"I enjoyed four unforgettable days exploring beautiful Ortigia -staying at the Grand Hotel Ortigia, which is a 5-star luxury hotel overlooking the harbor. It is just a short stroll to the must-see landmarks such as the ruins of the Temple of Apollo, the Aretusa Fountain, and the renowned Cathedral of Syracuse. it was built in 1890 and was completely renovated while preserving its classic old-world charm with marble floors, Corinthian columns, and beautiful art-filled common areas. They have an upscale rooftop restaurant and lounge on the third floor, which serves a sumptuous breakfast buffet and has great outdoor seating with spectacular views. I went up to the terrace one evening to enjoy the sunset with an Aperol Spritz and some nibbles and, after the sun went down, an exceptionally talented young man beautifully played his violin serenading the guests. Parking in the old city is a challenge, and not for the faint of heart. But the hotel does have a small lot nearby, but which seemed to stay full and was hard to find. With the helpful staff, I was able to register my rental car to allow me to drive to hotel which is in the restricted tourist zone and I moved my car to their lot one evening once the crowds had dissipated a bit. The staff couldn’t have been more helpful and even helped arrange a small group boat tour. This hotel truly deserves its name the Grand Hotel Ortigia Siracusa!"

Mangia's Brucoli, Sicily, Autograph Collection

10/10 Excellent

"Staying will be an extremely fond memory for my wife and I. After the first night, we both decided to make our stay here our official honeymoon. The view from our room allowed for an incredible view of Mt Etna. The staff is professional and polite and very friendly. The breakfast buffet is pretty outstanding with so many options. Unfortunately, we didn’t get to try the other restaurants but we were able to take advantage of the Lime Bar before leaving. They absolutely captured Sicily’s beautiful culture and atmosphere. We absolutely recommend staying at Mangia, hands down, with zero hesitation."

Hotel Como

8/10 Good

"The staff was very helpful and friendly. Although they have no parking there was plenty of free parking close by. The internet simply doesn't work. Don't count on using it on the room. You have to go to the lobby for it. The location is close enough that we walked to Ortigia and also to the archeological site. Not the prettiest site but had a good breakfast. There was a smell on the corridor/room that could be a mix of smoke or mold (couldn't identify it) but it wasn't that bad. Overall for the price it was good and I would stay there again."

Frequently asked questions

What is Epipoli like?

Travellers to the Epipoli neighbourhood in Syracuse will be sure to enjoy their stay.

What's a favourite place to stay in Epipoli?

Based on our traveller data, Hotel Relax is one of the top choices for your stay in Epipoli. This hotel offers a full-service spa and a restaurant.

How many hotels are there in the Epipoli area?

When you want to find places to stay in Syracuse, start by booking one of Expedia's 7 hotels and other accommodation options in Epipoli.

If I need to cancel my hotel reservation in Epipoli, will I receive a refund?

Yes, you'll find most hotel reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best deals in Epipoli.

What can I see and do in this Syracuse neighbourhood?

A few places to visit in the area around Epipoli include Cantine Pupillo, Greek Theatre of Syracuse and Latomia del Paradiso. Rope-makers' Cave and Ear of Dionysius are also worth a visit when you're out sightseeing in Syracuse.

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Our top choices for Epipoli hotels

1. B&B Kosmos

2. Hotel Relax

3. Hotel Parco delle Fontane

4. Maniace Boutique Hotel Ortigia UNA Esperienze

5. Algila' Ortigia Charme Hotel

6. Grand Hotel Villa Politi

7. UNA Hotels One Siracusa Wellness & SPA

8. Grand Hotel Ortigia Siracusa

9. Grande Albergo Alfeo

10. Mercure Siracusa Prometeo

11. Charme Hotel Henry's House

12. Grand Hotel Des Ètrangers - The Leading Hotels of the World

13. Palazzo Artemide - VRetreats, SLH Collection

14. Nostos rooms & Apartments

15. EGEO - Ortigia

16. Ortea Palace Hotel, Sicily, Autograph Collection

17. CinqueSuites Ortigia

18. Caportigia Boutique Hotel

19. Maecò Ortigia B&B

20. Archinuè Suite & Apartments

Compare popular hotels in Epipoli

Where to stay in Epipoli

Ortigia

Santa Lucia

Neapolis

Grottasanta

Tiche

Top Epipoli Hotel Reviews

Hotel Posta

Frequently asked questions

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