A long bridge spanning a river, surrounded by lush greenery and fields.

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Check availability on Greenville Spa Hotels

This weekend
6 Nov - 8 Nov
Next weekend
13 Nov - 15 Nov

Our top choices for Greenville hotels with a spa

Room

1. Hotel 27

Hotel 27
2.0 star property
Greenville
9.0 out of 10, Wonderful, (380 reviews)
"I had a great stay"
United States
Denise
The price is Rp1.944.936
Rp2.139.429 total
includes taxes & fees
14 Nov - 15 Nov
Hotel 27
A spacious living room with a large sofa, armchairs, and a fireplace.

2. Holiday Inn Express and Suites Greenville by IHG

Holiday Inn Express and Suites Greenville by IHG
2.5 star property
Greenville
8.0 out of 10, Very good, (781 reviews)
"The front desk associates were very friendly and accommodating. We enjoyed our stay and will stay again in the future."
United States
Annette
The price is Rp2.615.040
Rp2.876.544 total
includes taxes & fees
16 Nov - 17 Nov
Holiday Inn Express and Suites Greenville by IHG
A spacious room with wooden flooring, beige sofas, a wooden coffee table, and large windows offering a view of the outdoors.

3. Americas Best Value Inn & Suites Greenville

Americas Best Value Inn & Suites Greenville
2.0 star property
Greenville
6.6 out of 10, (595 reviews)
"Parking was great, and there were great restaurants right down the street."
United States
Cedric
The price is Rp1.234.880
Rp1.358.368 total
includes taxes & fees
14 Nov - 15 Nov
Americas Best Value Inn & Suites Greenville
A modern hotel dining area with a large table and chairs, a kitchen area with appliances, and a large window offering a view.

4. Econo Lodge Greenville

Econo Lodge Greenville
2.0 star property
Greenville
5.6 out of 10, (292 reviews)
"I liked the free breakfast. Staff did everything asked of them."
United States
Darryl M
The price is Rp1.080.520
Rp1.188.572 total
includes taxes & fees
5 Dec - 6 Dec
Econo Lodge Greenville
A historic building with a central tower, arched windows, and a symmetrical facade.

5. Days Inn by Wyndham Greenville MS

Days Inn by Wyndham Greenville MS
2.0 star property
Greenville
5.2 out of 10, (1,004 reviews)
"I had a great stay at this hotel! The room was nice and clean, the staff was friendly, and everything went smoothly. I enjoyed my stay and would definitely recommend this hotel to anyone looking for a nice place to stay. I would stay here again!"
United States
Kennedy
The price is Rp1.089.600
Rp1.198.560 total
includes taxes & fees
17 Nov - 18 Nov
Days Inn by Wyndham Greenville MS
A modern reception area with a white counter, glass doors leading to a fitness room, and a large abstract painting on the wall.

6. Cotton House, Cleveland, a Tribute Portfolio Hotel

Cotton House, Cleveland, a Tribute Portfolio Hotel
3.5 star property
Cleveland
9.0 out of 10, Wonderful, (723 reviews)
"Everything was beautiful I enjoyed my stay. The staff was friendly and very catering to my needs. The rooms are beautiful."
United States
Monica
The price is Rp2.524.240
Rp2.751.422 total
includes taxes & fees
22 Nov - 23 Nov
Cotton House, Cleveland, a Tribute Portfolio Hotel
A spacious lobby with a grand chandelier, a round seating area, and a second-floor balcony.

7. Harlow's Casino Resort & Spa

Harlow's Casino Resort & Spa
3.5 star property
Greenville
8.0 out of 10, Very good, (1,000 reviews)
"The service and staff were very polite friendly and kind. We will definitely return"
United States
LaTonya
The price is Rp2.108.376
Rp2.319.214 total
includes taxes & fees
8 Nov - 9 Nov
Harlow's Casino Resort & Spa
A modern reception area with a curved counter, seating with cushions, and a view of the outdoors.

8. Tru By Hilton Greenville

Tru By Hilton Greenville
2.5 star property
Greenville
8.0 out of 10, Very good, (645 reviews)
"We really enjoyed our stay at the Tru Blue Hilton in Greenville. The town, people, and local attractions were easily accessible, and we liked the convenience of the hotel to downtown."
United States
Joan
The price is Rp2.219.766
Rp2.441.742 total
includes taxes & fees
2 Dec - 3 Dec
Tru By Hilton Greenville
A spacious restaurant with high ceilings, wooden beams, and modern lighting fixtures.

9. Lyric Hotel West End, Trademark Collection by Wyndham

Lyric Hotel West End, Trademark Collection by Wyndham
3.0 star property
Cleveland
8.4 out of 10, Very good, (344 reviews)
"Clean facilities, comfortable bed."
United States
Britiani
The price is Rp2.271.816
Rp2.476.280 total
includes taxes & fees
8 Nov - 9 Nov
Lyric Hotel West End, Trademark Collection by Wyndham
A bedroom with a bed, a nightstand, a dresser, and a wall-mounted TV.

10. Motel 6 Cleveland, MS - Delta State University

Motel 6 Cleveland, MS - Delta State University
2.0 star property
Cleveland
8.2 out of 10, Very good, (341 reviews)
"Clean, comfy, good location"
United States
Richelle
The price is Rp1.332.762
Rp1.452.710 total
includes taxes & fees
12 Nov - 13 Nov
Motel 6 Cleveland, MS - Delta State University
A modern living room with a brick wall, a flat-screen TV, and a fireplace. There are two blue sofas with red cushions, a glass coffee table, and a small wooden side table.

11. Quality Inn Indianola

Quality Inn Indianola
2.5 star property
Indianola
7.6 out of 10, Good, (176 reviews)
"Clean"
United States
Dennis
The price is Rp1.191.457
Rp1.298.688 total
includes taxes & fees
1 Dec - 2 Dec
Quality Inn Indianola
A Super 8 hotel with a large sign, covered parking, and well-maintained landscaping.

12. Super 8 by Wyndham Indianola

Super 8 by Wyndham Indianola
2.0 star property
Indianola
7.4 out of 10, Good, (416 reviews)
"Staff was helpful and parking was plentiful breakfast was okay, a cut back from previous stay."
United States
Mary
The price is Rp1.471.608
Rp1.604.053 total
includes taxes & fees
15 Nov - 16 Nov
Super 8 by Wyndham Indianola
Room

13. Americas Best Value Inn Indianola

Americas Best Value Inn Indianola
2.5 star property
Indianola
7.6 out of 10, Good, (221 reviews)
"The room was clean and smelled very fresh."
United States
Nathaniel
The price is Rp1.325.680
Rp1.444.991 total
includes taxes & fees
6 Nov - 7 Nov
Americas Best Value Inn Indianola
A hotel dining area with a large granite island, multiple chairs, pendant lighting, a breakfast bar, and a view of the outside.

14. Holiday Inn Express Hotel & Suites Cleveland by IHG

Holiday Inn Express Hotel & Suites Cleveland by IHG
2.5 star property
Cleveland
7.8 out of 10, Good, (1,004 reviews)
"The room was clean and the staff there are very nice."
United States
Linda
The price is Rp2.052.080
Rp2.236.768 total
includes taxes & fees
5 Dec - 6 Dec
Holiday Inn Express Hotel & Suites Cleveland by IHG
A hotel room with a bed, a dresser, a television, and a small refrigerator.

15. c towninn and suites

c towninn and suites
2.0 star property
Cleveland
5.6 out of 10, (32 reviews)
"Rm clean air work not professional at all. I will not stay again"
United States
Angela
The price is Rp898.920
Rp979.822 total
includes taxes & fees
6 Nov - 7 Nov
c towninn and suites
A hotel reception area with a coffee station, a wall with a colorful pattern, and a sofa in the background.

16. Hampton Inn

Hampton Inn
2.0 star property
Indianola
The price is Rp2.762.136
Rp3.259.339 total
includes taxes & fees
17 Nov - 18 Nov
Hampton Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Greenville

Pool
Hot tub

Top Greenville Hotel Reviews

Frequently asked questions

Looking to holiday at a spa hotel in Greenville?
Forget the stress of everyday life and book yourself a lush spa hotel. Enjoy the live music scene and restaurants in Greenville—your day trip starts here. Enjoy the entertainment choices and riverfront during your holiday. Spa hotels are the perfect way to take a break from your daily routine and add a layer of luxury to your stay.
What is the best spa hotel in Greenville?
Harlow's Casino Resort & Spa is a top spa hotel featuring 3 restaurants, 3 bars, a casino and a 24-hour fitness centre. Enjoy a facial, body scrub or detox wrap at the on-site spa.
How many spa hotels are there in Greenville?
Among Expedia's 18 accommodation options in Greenville, there is 1 spa hotel.
What's there to see and do in Greenville?
Take in some sights and attractions while you're in Greenville by visiting Trop Casino Greenville, Greenville Country Club and Harlow's Casino Resort & Spa. If you have a bit of extra time while you're in the area, you might want to check out Mississippi River and 1927 Flood Museum.
What is a Greenville spa hotel?
Spa hotels in Greenville feature on-site spas offering services such as couples massages and a selection of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are ideal if you are looking for some R&R during your holiday.