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6 Nov - 8 Nov
Next weekend
13 Nov - 15 Nov

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Our top choices for Illinois Medical District hotels

A modern indoor pool area with lounge chairs, a wooden table, and large windows.

1. Hampton Inn & Suites Chicago Medical District UIC

Hampton Inn & Suites Chicago Medical District UIC
2.5 star property
Illinois Medical District
9.6 out of 10, Exceptional, (858 reviews)
"Love the rooms and the area of the hotel"
United States
Chad
The price is Rp2.145.604
Rp2.550.909 total
includes taxes & fees
22 Nov - 23 Nov
Hampton Inn & Suites Chicago Medical District UIC
A spacious living area with a pool table, comfortable seating, a fireplace, and large windows.

2. Hyatt Place Chicago Medical/University District

Hyatt Place Chicago Medical/University District
3.0 star property
Illinois Medical District
9.0 out of 10, Wonderful, (1,498 reviews)
"Staff very hospitable! Nice place."
United States
John F
The price is Rp1.914.064
Rp2.275.631 total
includes taxes & fees
22 Nov - 23 Nov
Hyatt Place Chicago Medical/University District
A grand hotel facade with classical architecture, featuring tall columns, ornate detailing, and a prominent entrance with a marquee.

3. Hyatt House Chicago Medical/University District

Hyatt House Chicago Medical/University District
3.5 star property
Illinois Medical District
9.2 out of 10, Wonderful, (1,618 reviews)
"We had a lovely stay!"
Netherlands
lieneke
The price is Rp1.991.244
Rp2.367.388 total
includes taxes & fees
22 Nov - 23 Nov
Hyatt House Chicago Medical/University District
A rooftop terrace with outdoor seating, a view of the city skyline, and a river.

4. LondonHouse Chicago, Curio Collection by Hilton

LondonHouse Chicago, Curio Collection by Hilton
4.5 star property
The Loop, 4.6 km from Illinois Medical District
9.4 out of 10, Exceptional, (3,886 reviews)
"The room was very clean, staff was very friendly and helpful!"
United States
Lorena
The price is Rp2.608.684
Rp3.641.542 total
includes taxes & fees
23 Nov - 24 Nov
LondonHouse Chicago, Curio Collection by Hilton
A room with two chairs and a small table, a large window with a city view at night.

5. Eurostars Magnificent Mile

Eurostars Magnificent Mile
4.0 star property
River North, 4.8 km from Illinois Medical District
9.0 out of 10, Wonderful, (3,980 reviews)
"Nice rooms and great location"
United States
Gabriela
The price is Rp2.615.367
Rp3.109.411 total
includes taxes & fees
22 Nov - 23 Nov
Eurostars Magnificent Mile
A person relaxing on a sofa with a window view of a building, a table with a glass of wine, and a vase with flowers.

6. L7 Chicago by LOTTE

L7 Chicago by LOTTE
4.5 star property
Theatre District, 4.5 km from Illinois Medical District
9.6 out of 10, Exceptional, (5,175 reviews)
"Amazing hotel will stay again"
United States
Matthew
The price is Rp2.633.018
Rp3.130.393 total
includes taxes & fees
22 Nov - 23 Nov
L7 Chicago by LOTTE
A cityscape at dusk with illuminated skyscrapers, a river, and a bridge.

7. Swissotel - Chicago

Swissotel - Chicago
4.5 star property
5 km from Illinois Medical District
9.0 out of 10, Wonderful, (3,566 reviews)
"Good location and nice hotel"
United States
Oleg
The price is Rp2.351.720
Rp3.435.690 total
includes taxes & fees
26 Nov - 27 Nov
Swissotel - Chicago
The Riu Plaza Chicago Hotel facade with a grand entrance, large windows, and a modern architectural design.

8. Hotel Riu Plaza Chicago

Hotel Riu Plaza Chicago
4.0 star property
Streeterville, 5.1 km from Illinois Medical District
9.4 out of 10, Exceptional, (5,645 reviews)
"All the stay was perfect, location is near to all the best places"
Mexico
JESUS VERA
The price is Rp2.568.538
Rp3.571.296 total
includes taxes & fees
23 Nov - 24 Nov
Hotel Riu Plaza Chicago
A modern hotel lobby with a long blue sofa, numbered cushions, and hanging planters.

9. Hilton Vacation Club Hotel Blake Chicago

Hilton Vacation Club Hotel Blake Chicago
4.0 star property
The Loop, 3.8 km from Illinois Medical District
9.6 out of 10, Exceptional, (1,216 reviews)
"Great location from both airports. Lovely hotel clean and convenient"
United Kingdom
Kanokkan
The price is Rp2.911.048
Rp3.460.751 total
includes taxes & fees
22 Nov - 23 Nov
Hilton Vacation Club Hotel Blake Chicago
A cityscape with modern high-rise buildings, a river, and a boat.

10. Hyatt Regency Chicago

Hyatt Regency Chicago
4.0 star property
The Loop, 4.8 km from Illinois Medical District
9.4 out of 10, Exceptional, (3,506 reviews)
"Wonderful will stay again"
United States
Kristee
The price is Rp2.818.432
Rp3.998.602 total
includes taxes & fees
22 Nov - 23 Nov
Hyatt Regency Chicago
A Fairmont hotel with a prominent entrance, large windows, and a sculpture on the facade.

11. Fairmont Chicago at Millennium Park

Fairmont Chicago at Millennium Park
4.5 star property
The Loop, 4.8 km from Illinois Medical District
8.8 out of 10, Excellent, (2,327 reviews)
"Great location!"
United States
Eric
The price is Rp3.613.840
Rp4.944.605 total
includes taxes & fees
24 Nov - 25 Nov
Fairmont Chicago at Millennium Park
A multi-story hotel with a modern glass facade, located in an urban setting with a parking lot and street views.

12. Hyatt Place Chicago/River North

Hyatt Place Chicago/River North
3.5 star property
River North, 4.4 km from Illinois Medical District
9.2 out of 10, Wonderful, (1,919 reviews)
"Great location, clean hotel and overall a great place to stay."
United States
Pamela
The price is Rp2.288.160
Rp2.720.394 total
includes taxes & fees
22 Nov - 23 Nov
Hyatt Place Chicago/River North
The Intercontinental hotel facade with a large American flag and a floral display.

13. InterContinental Chicago Magnificent Mile by IHG

InterContinental Chicago Magnificent Mile by IHG
4.5 star property
Magnificent Mile, 4.9 km from Illinois Medical District
9.2 out of 10, Wonderful, (3,416 reviews)
"Excellent location, lots of shops and restaurants nearby and walking distance to many sights."
Canada
Faye
The price is Rp3.323.280
Rp4.586.648 total
includes taxes & fees
6 Dec - 7 Dec
InterContinental Chicago Magnificent Mile by IHG
A rooftop lounge with a city view, featuring a sofa, tables, and a fire feature.

14. Hyatt House Chicago/West Loop-Fulton Market

Hyatt House Chicago/West Loop-Fulton Market
3.5 star property
2.3 km from Illinois Medical District
9.0 out of 10, Wonderful, (1,308 reviews)
"Loved the continental breakfast and how close different bars and restaurants were at :)"
United States
Carole
The price is Rp1.894.088
Rp2.251.881 total
includes taxes & fees
22 Nov - 23 Nov
Hyatt House Chicago/West Loop-Fulton Market
A multi-level atrium with a central spiral staircase, multiple seating areas, and a pool.

15. Embassy Suites by Hilton Chicago Downtown River North

Embassy Suites by Hilton Chicago Downtown River North
4.0 star property
River North, 4.7 km from Illinois Medical District
8.6 out of 10, Excellent, (5,973 reviews)
"Great location! Walkable to several nice spots and easy to get to parking."
United States
Stacy
The price is Rp2.238.220
Rp2.661.018 total
includes taxes & fees
6 Dec - 7 Dec
Embassy Suites by Hilton Chicago Downtown River North
A cityscape with tall buildings, a river, and a bridge.

16. The Royal Sonesta Chicago Downtown

The Royal Sonesta Chicago Downtown
4.0 star property
The Loop, 4.6 km from Illinois Medical District
9.4 out of 10, Exceptional, (3,670 reviews)
"Excellent hotel"
Canada
Frédéric
The price is Rp2.433.440
Rp3.474.237 total
includes taxes & fees
23 Nov - 24 Nov
The Royal Sonesta Chicago Downtown
A modern indoor pool area with clear glass walls, lounge chairs, and a view of city buildings.

17. Hotel 505 River North

Hotel 505 River North
4.5 star property
River North, 4.6 km from Illinois Medical District
9.2 out of 10, Wonderful, (3,002 reviews)
"Great stay!"
United States
Miya
The price is Rp2.021.208
Rp2.984.277 total
includes taxes & fees
22 Nov - 23 Nov
Hotel 505 River North
A hotel room with a large window offering a city view, a bed, a desk, and a chair.

18. Courtyard by Marriott Chicago Magnificent Mile

Courtyard by Marriott Chicago Magnificent Mile
3.0 star property
Streeterville, 5.1 km from Illinois Medical District
9.0 out of 10, Wonderful, (2,080 reviews)
"Great location Staff was terrific"
United States
Richard
The price is Rp2.000.324
Rp2.378.185 total
includes taxes & fees
6 Dec - 7 Dec
Courtyard by Marriott Chicago Magnificent Mile
A grand lobby with a staircase, ornate chandeliers, and a clock on the wall.

19. Palmer House a Hilton Hotel

Palmer House a Hilton Hotel
4.0 star property
Theatre District, 4.2 km from Illinois Medical District
8.6 out of 10, Excellent, (2,726 reviews)
"Beautiful hotel with wonderful staff!"
United States
Christy
The price is Rp2.393.634
Rp3.385.927 total
includes taxes & fees
24 Nov - 25 Nov
Palmer House a Hilton Hotel
A modern hotel lobby with a reception desk, marble flooring, and elegant chandeliers.

20. Silversmith Hotel Chicago Downtown

Silversmith Hotel Chicago Downtown
4.0 star property
Theatre District, 4.2 km from Illinois Medical District
9.2 out of 10, Wonderful, (2,424 reviews)
"Great location and friendly staff"
United States
William
The price is Rp2.069.968
Rp3.015.227 total
includes taxes & fees
22 Nov - 23 Nov
Silversmith Hotel Chicago Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare top hotels in Illinois Medical District

A modern indoor pool area with lounge chairs, a wooden table, and large windows.

Hampton Inn & Suites Chicago Medical District UIC

2.5 star property
Illinois Medical District
View
A spacious living area with a pool table, comfortable seating, a fireplace, and large windows.

Hyatt Place Chicago Medical/University District

3.0 star property
Illinois Medical District
View
A grand hotel facade with classical architecture, featuring tall columns, ornate detailing, and a prominent entrance with a marquee.

Hyatt House Chicago Medical/University District

3.5 star property
Illinois Medical District
View
A rooftop terrace with outdoor seating, a view of the city skyline, and a river.

LondonHouse Chicago, Curio Collection by Hilton

4.5 star property
The Loop, 4.6 km from Illinois Medical District
View
A room with two chairs and a small table, a large window with a city view at night.

Eurostars Magnificent Mile

4.0 star property
River North, 4.8 km from Illinois Medical District
View
9.6
Exceptional
858 reviews
9.0
Wonderful
1,498 reviews
9.2
Wonderful
1,618 reviews
9.4
Exceptional
3,886 reviews
9.0
Wonderful
3,980 reviews
The price is Rp2.145.604
Rp2.550.909 total
includes taxes & fees
22 Nov - 23 Nov
The price is Rp1.914.064
Rp2.275.631 total
includes taxes & fees
22 Nov - 23 Nov
The price is Rp1.991.244
Rp2.367.388 total
includes taxes & fees
22 Nov - 23 Nov
The price is Rp2.608.684
Rp3.641.542 total
includes taxes & fees
23 Nov - 24 Nov
The price is Rp2.615.367
Rp3.109.411 total
includes taxes & fees
22 Nov - 23 Nov
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • No Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • No Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • No Pool
  • Yes, Spa
  • No Pet-friendly
  • Yes, WiFi included
  • No Parking
  • No Breakfast included
  • No Pool
  • Yes, Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking

Where to stay in Illinois Medical District

Find the best Illinois Medical District areas for the activities you enjoy most.
A cityscape with tall skyscrapers and a historic tower.

Downtown Chicago

The heart of the Midwest’s glittering metropolis has many offerings, from shopping and dining to parks, museums and exciting contemporary public art.

A busy urban street at dusk with tall buildings, a historic tower, and pedestrians.
Photo by © City of Chicago
Open Photo by © City of Chicago

Magnificent Mile

Shopaholics need look no further this glittering street packed with boutique and luxury shops, famous department stores and cafes.

A river with yellow boats, a bridge, and tall buildings.

The Loop

Bordered roughly by the surrounding elevated train circuit, this Chicago neighborhood has restaurants, galleries, parks and a giant silver bean.

A large, historic building with a central tower and multiple windows, located near a body of water.

River North

Known for its fantastic nightlife, stunning river views and popular shops, there's plenty to explore in River North. Top attractions like Merchandise Mart and Bally's Casino Chicago are major draws. Catch the metro at Merchandise Mart Station or Chicago Station (Brown Line) to see more of the city.

A river with a city skyline in the background, surrounded by green trees and grass.

Lincoln Park

Both a neighborhood and a park, this northern Chicago area has gorgeous scenery, residential streets lined with stately homes and extensive shopping and dining.

Top Illinois Medical District Hotel Reviews

THE MIDLAND HOTEL, Chicago, a Tribute Portfolio Hotel

THE MIDLAND HOTEL, Chicago, a Tribute Portfolio Hotel

10/10 Excellent
"Nice environment and very reasonable prices..right downtown so great location!"
Ebony 2-night trip
Posted 8 hours ago
THE MIDLAND HOTEL, Chicago, a Tribute Portfolio Hotel

Frequently asked questions

What's it like in Illinois Medical District?
Guests are sure to enjoy their time checking out all that Chicago's Illinois Medical District neighbourhood has to offer.
Where is the best place to stay in Illinois Medical District?
Based on Expedia customer reviews, Hampton Inn & Suites Chicago Medical District UIC is the highest ranked property in Illinois Medical District. This hotel is a short 15-minute walk from United Center, and it offers free breakfast and an indoor pool. Other top choices in the neighbourhood include Hyatt House Chicago Medical/University District and Hyatt Place Chicago Medical/University District.
How many hotels are there in the Illinois Medical District area?
If you're searching for places to stay in Chicago, choose from one of Expedia's 16 hotels and other accommodation options in Illinois Medical District.
If I need to cancel my hotel reservation in Illinois Medical District, will I receive a refund?
Yes, most room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the top deals on offer in Illinois Medical District.
What can I see and do in this Chicago neighbourhood?
Don't miss favourite places to visit in the surrounding area, such as Soldier Field, United Center and Michigan Avenue. Malcolm X College and Michael Jordan Statue are also worth a visit when you're out sightseeing in Chicago.
How can I get around Illinois Medical District and the greater Chicago area?
Ready to get out and explore the city? Polk Station (Pink Line) is the closest metro station.