The Best Hotels Closest to James S. McDonnell Prologue Room in St. Louis - 2026 Updated Prices

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Our top choices for James S. McDonnell Prologue Room hotels

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

A spacious indoor area with multiple wooden tables and chairs, large windows, and a high ceiling with exposed beams.

A hotel room with a bed, a desk, a television, and a lamp.

A spacious indoor area with a high ceiling and large windows, featuring multiple seating areas with sofas and chairs, and a visible outdoor view through the windows.

1. Pear Tree Inn St. Louis Airport

2.6 km from James S. McDonnell Prologue Room

Monica

Rp1.603.442

Rp1.887.861 total

includes taxes & fees

4 Oct - 5 Oct

A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

A modern dining area with a long table, multiple chairs, and a unique chandelier.

A multi-story hotel with a stone facade, a covered entrance, and a parking lot.

A modern lobby with blue seating, a reception desk, and large windows.

2. Hyatt Select St. Louis Airport

1.9 km from James S. McDonnell Prologue Room

Maxine

Rp1.959.980

Rp2.410.274 total

includes taxes & fees

3 Oct - 4 Oct

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

A lobby with two orange armchairs, a small table, a flat-screen TV, framed pictures, and a wall-mounted shelf with decorative items.

A Wingate hotel with a covered entrance, outdoor seating, and a parking lot.

A hotel room with a desk, chair, TV, and a framed picture on the wall.

3. Wingate by Wyndham St. Louis Airport

2.5 km from James S. McDonnell Prologue Room

Tessa

Rp1.665.983

Rp1.961.584 total

includes taxes & fees

27 Sept - 28 Sept

A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.

A hotel room with a bed, two armchairs, a sofa, a small table, and a nightstand.

A modern kitchen with a stainless steel range hood, a bar area with stools, and a large window providing a view of the outdoors.

A hotel reception area with a counter, seating, and a staircase.

4. Drury Inn & Suites St. Louis Airport

2.1 km from James S. McDonnell Prologue Room

Hope

Rp2.048.892

Rp2.404.127 total

includes taxes & fees

4 Oct - 5 Oct

An indoor swimming pool with clear glass walls, blue lounge chairs, and a lifeguard stand.

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

A snack vending machine with various snack options.

A dining area with tables and chairs, a blue sofa, and a patterned carpet.

5. Hampton Inn By Hilton St Louis Airport

2 km from James S. McDonnell Prologue Room

Leia

Rp2.307.581

Rp2.753.820 total

includes taxes & fees

8 Oct - 9 Oct

A buffet with fruits, pastries, and beverages.

The Renaissance Hotel with a modern architectural design, featuring a prominent central entrance and a symmetrical facade.

A spacious hotel lobby with multiple seating areas, a reception desk, and large windows offering a view of the cityscape.

A modern living room with a flat-screen TV, comfortable seating, and decorative items on shelves.

6. Renaissance St. Louis Airport Hotel

Berkeley, 2 km from James S. McDonnell Prologue Room

Anthony

Rp2.116.775

Rp2.476.373 total

includes taxes & fees

4 Oct - 5 Oct

A breakfast buffet with labeled sections for fruit and cereal.

A conference room with a long table, chairs, water bottles, a phone, and a notepad.

A Holiday Inn Express & Suites building with a covered entrance, a truck with the hotel branding, and a clear sky.

A hotel room with a large bed, a separate bathroom with a bathtub, a desk with a chair, and a large window with curtains.

7. Holiday Inn Express & Suites St Louis Airport by IHG

2 km from James S. McDonnell Prologue Room

Keneace

Rp2.209.432

Rp2.707.964 total

includes taxes & fees

4 Oct - 5 Oct

A modern dining area with round tables, orange chairs, and a decorative wall with pottery.

A modern lobby with seating areas, a reception desk, and a bar area.

A Marriott hotel with a large building, multiple flags, and a well-lit entrance area.

A swimming pool with a glass enclosure, a lounge area with orange chairs, and a view of a landscaped garden.

8. Marriott St. Louis Airport

2.4 km from James S. McDonnell Prologue Room

Chris

Rp2.360.433

Rp2.816.893 total

includes taxes & fees

3 Oct - 4 Oct

A modern interior with a wooden panel wall, a kitchen area, and a dining space with pendant lighting.

A hotel room with a large bed, a chair, a table, and a cityscape mural on the wall.

A modern hotel with a prominent DoubleTree by Hilton sign, a well-lit entrance, and a landscaped front yard.

A hotel room with a bed, a desk, a chair, a small table, a framed artwork, and a bathroom with a mirror and sink.

9. DoubleTree by Hilton St. Louis Airport

2.1 km from James S. McDonnell Prologue Room

Samone

Rp2.042.066

Rp2.396.118 total

includes taxes & fees

2 Oct - 3 Oct

A bar area with a long counter, multiple seating options, and a television screen displaying a program.

A spacious lobby with a reception desk, seating area, and a modern ceiling design.

A multi-story hotel with a central courtyard, surrounded by trees and a parking lot.

A hotel lobby with a central seating area featuring sofas and tables, a large TV screen displaying a sports game, and a bar area with chairs and a counter.

10. Hilton St. Louis Airport

1.9 km from James S. McDonnell Prologue Room

raymond

Rp2.455.925

Rp2.930.852 total

includes taxes & fees

2 Oct - 3 Oct

A hotel dining area with multiple tables and chairs, a sofa, and a large window with curtains.

A hotel with a beige facade, a clear sign reading "Quality Inn," and a parking lot with a red car.

A hotel room with a round wooden dining table, a sofa, two lamps, and framed pictures on the walls.

A hotel room with two beds, a desk with a lamp, a television, and a painting on the wall.

11. Quality Inn Florissant - St Louis

3.1 km from James S. McDonnell Prologue Room

Sharonda

Rp1.196.479

Rp1.413.036 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a bed, a desk, a chair, a flat-screen TV, and a wooden floor.

A reception area with a green wall, a reception desk, and a wooden floor.

A compact kitchen with a sink, stove, and white cabinets.

A parking lot with several cars, a U-Haul truck, and a building with a green sign for HomeTowne Studios.

12. HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh

2.9 km from James S. McDonnell Prologue Room

Kimberly

Rp1.247.260

Rp1.524.626 total

includes taxes & fees

5 Oct - 6 Oct

A modern living room with a flat-screen TV, a sofa, a coffee table, and a potted plant.

A stairwell with a metal railing, a trash can, and a window with a view of trees.

A hotel room with a bed, bedside tables, a desk, and a window with a city view.

A modern kitchen with dark cabinets, a white countertop, a stove, a microwave, and a sink.

13. Welcome Suites Hazelwood

3 km from James S. McDonnell Prologue Room

Arutyun

Rp1.336.350

Rp1.633.529 total

includes taxes & fees

27 Sept - 28 Sept

A hotel room with a bed, bedside table, lamp, TV, and a desk with a chair.

A spacious lobby with a patterned tile floor, a staircase, and seating areas.

A kitchen with a built-in refrigerator, a coffee maker, and a microwave. There are cabinets and a countertop with various items on it.

A reception area with a marble floor, a reception desk, and a sign that says "Quality."

14. Quality Inn Saint Louis Airport

2 km from James S. McDonnell Prologue Room

Gordon

Rp1.056.786

Rp1.299.702 total

includes taxes & fees

4 Oct - 5 Oct

A modern lobby with orange seating, a flat-screen TV, and a stone accent wall.

A spacious lobby with a large sectional sofa, a reception desk, and a bar area.

A hotel pool area with a hot tub, lounge chairs, and a 'No Diving Allowed' sign.

A hotel room with two beds, a headboard, bedside lamps, a clock, and a window with curtains.

15. Drury Plaza Hotel St. Louis St. Charles

12.8 km from James S. McDonnell Prologue Room

Robert

Rp2.423.070

Rp2.808.991 total

includes taxes & fees

1 Oct - 2 Oct

A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

A spa bath with a sign indicating a capacity of 8 persons.

A lobby with a reception desk, seating area with sofas and ottomans, and a patterned rug.

A Drury Plaza Hotel with a large parking lot and multiple cars parked in front.

16. Drury Plaza Hotel St. Louis Brentwood

13.6 km from James S. McDonnell Prologue Room

Jeana

Rp2.423.070

Rp2.876.749 total

includes taxes & fees

4 Oct - 5 Oct

An outdoor patio with a fire pit, seating, and a building in the background.

A modern hotel lobby with a bar area, a large dining table, and a seating area with chairs.

A modern bar area with a digital menu display, a seating area with a long table and chairs, and a wall with a colorful abstract design.

A modern bar area with a wooden counter, a beverage dispenser, and a menu board.

17. Courtyard by Marriott St. Louis Brentwood

13.5 km from James S. McDonnell Prologue Room

Aaron

Rp2.029.470

Rp2.478.547 total

includes taxes & fees

4 Oct - 5 Oct

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

A hotel reception area with a modern design, featuring a reception desk, a wall with a welcome sign, and a view of the lobby.

A hotel with a modern design, featuring a large entrance, multiple floors, and a parking lot.

A snack and treat display with various products, including chips and beverages, in a store setting.

18. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 14.4 km from James S. McDonnell Prologue Room

Jennifer

Rp2.469.218

Rp2.911.924 total

includes taxes & fees

1 Oct - 2 Oct

A multi-story building with a grand entrance, large windows, and a well-lit facade at night.

A dining room with two tables, chairs, a chandelier, and a fireplace.

A wooden table set for a meal under a tent with string lights, surrounded by chairs on a grassy area.

A hallway with a chandelier, a dining table with chairs, and a vase of flowers.

19. Grand Center Inn

15.5 km from James S. McDonnell Prologue Room

Leon and Janis

Rp3.189.422

Rp3.761.254 total

includes taxes & fees

1 Oct - 2 Oct

A rooftop terrace with a fire feature, outdoor seating, and a city view.

A modern lounge area with a fireplace, a flat-screen TV, and a dining area with chairs and tables.

A hotel with a modern brick facade, large windows, and a well-lit entrance.

A modern bar area with round tables and blue chairs, a wooden bar counter, and a television mounted on the wall.

20. Residence Inn By Marriott St. Louis Clayton

Clayton, 11 km from James S. McDonnell Prologue Room

Donna

Rp3.027.804

Rp3.640.890 total

includes taxes & fees

27 Sept - 28 Sept

View all properties

Compare popular hotels close to James S. McDonnell Prologue Room

Property	Property class	Guest rating
Pear Tree Inn St. Louis Airport	9.2 Wonderful 3,258 reviews	View
Hyatt Select St. Louis Airport	9.2 Wonderful 1,004 reviews	View
Wingate by Wyndham St. Louis Airport	9.2 Wonderful 1,712 reviews	View
Drury Inn & Suites St. Louis Airport	9.2 Wonderful 1,419 reviews	View
Hampton Inn By Hilton St Louis Airport	9.0 Wonderful 224 reviews	View

Top James S. McDonnell Prologue Room Hotel Reviews

Pear Tree Inn St. Louis Airport

8/10 Good

"The breakfast was adequate, but not impressive. They had no tea. The microwave was old and had limited power. The bathroom sinks have a faucet off to the side of the sink. It makes it less convenient to use for washing."

Renaissance St. Louis Airport Hotel

10/10 Excellent

"Will definitely book again through them. Great price for the time I stayed and close to everything"

La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North

10/10 Excellent

"They accommodated me with a late check out. I appreciate that!"

Wingate by Wyndham St. Louis Airport

8/10 Good

"Adrienne was so friendly and helpful with checking in. Also shuttle service was terrific!"

Hampton Inn By Hilton St Louis Airport

10/10 Excellent

"Great place to stay, close to the airport, can use the shuttle and pay for parking at the hotel, cheaper than at the airport."

Hilton St. Louis Airport

10/10 Excellent

"Service"

Comfort Inn & Suites Hazelwood - St. Louis

10/10 Excellent

"Best time ever"

Other attractions near James S. McDonnell Prologue Room

Blacks in Flight Mural

You can enjoy some culture when you stop by Blacks in Flight Mural in St. Louis. Experience the area's fascinating museums and acclaimed art galleries.

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Payne-Gentry Historical House

7.0/10 (37 reviews)

Find out about the history of Bridgeton when you take a trip to Payne-Gentry Historical House. Experience the acclaimed theatre scene or attend a sporting event in this family-friendly area.

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Blanche M. Touhill Performing Arts Center

10.0/10 (2 reviews)

Enjoy an outing to Blanche M. Touhill Performing Arts Center during your stay in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

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Old St. Ferdinand Shrine

2.0/10 (1 review)

You can spend time exploring the galleries in Old St. Ferdinand Shrine during your travels in Florissant. Experience the great live music and acclaimed theatre scene in this family-friendly area.

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St. Louis Mercantile Library

St. Louis Mercantile Library is just one of the places to see in Normandy, so why not enjoy the other things to explore during your travels? Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

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St. Louis Car Museum

9.2/10 (5 reviews)

You can spend time studying the exhibits at St. Louis Car Museum during your travels in Overland. Experience the acclaimed theatre scene and great live music in this family-friendly area.

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St. Louis Kaplan Feldman Holocaust Museum

6.0/10 (1 review)

You can spend time exploring the galleries in St. Louis Kaplan Feldman Holocaust Museum during your travels in St. Louis. Experience the great live music and acclaimed theatre scene in this family-friendly area.

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New Jewish Theatre

6.0/10 (1 review)

You can make plans for a show at New Jewish Theatre during your stay in St. Louis. Experience the acclaimed theatre scene or attend a sporting event in this family-friendly area.

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Frequently asked questions

What's the area like around James S. McDonnell Prologue Room?

James S. McDonnell Prologue Room is located in a welcoming area of St. Louis known for its array of dining options and sporting events. You'll find 116 hotels and other accommodations within a few miles for a convenient home base.

Where is the best place to stay close to James S. McDonnell Prologue Room?

Renaissance St. Louis Airport Hotel is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an indoor pool. It's located 1.2 mi (2 km) from James S. McDonnell Prologue Room. Other good choices within a few miles include Pear Tree Inn St. Louis Airport and Drury Inn & Suites St. Louis Airport.

How many hotels will I be able to find near James S. McDonnell Prologue Room?

Expedia has 116 hotels and other accommodation options a few miles from James S. McDonnell Prologue Room.

If I need to cancel the hotel reservation for my stay near James S. McDonnell Prologue Room, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within a 24-hour period of booking. Add your dates and click on "Search", then you can filter by "fully refundable" to view the best options available near James S. McDonnell Prologue Room.

What can I see and do near James S. McDonnell Prologue Room?

You'll want to browse the exhibits at Payne-Gentry Historical House and St. Louis Car Museum. Create some family memories at Par-Tee Recreation Center and Blanche M. Touhill Performing Arts Center. Old St. Ferdinand Shrine and St. Louis Mercantile Library are both worth a visit while you're out exploring.

Search Hotels Near James S. McDonnell Prologue Room, St. Louis

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for James S. McDonnell Prologue Room hotels

1. Pear Tree Inn St. Louis Airport

2. Hyatt Select St. Louis Airport

3. Wingate by Wyndham St. Louis Airport

4. Drury Inn & Suites St. Louis Airport

5. Hampton Inn By Hilton St Louis Airport

6. Renaissance St. Louis Airport Hotel

7. Holiday Inn Express & Suites St Louis Airport by IHG

8. Marriott St. Louis Airport

9. DoubleTree by Hilton St. Louis Airport

10. Hilton St. Louis Airport

11. Quality Inn Florissant - St Louis

12. HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh

13. Welcome Suites Hazelwood

14. Quality Inn Saint Louis Airport

15. Drury Plaza Hotel St. Louis St. Charles

16. Drury Plaza Hotel St. Louis Brentwood

17. Courtyard by Marriott St. Louis Brentwood

18. Hampton Inn & Suites St. Louis at Forest Park

19. Grand Center Inn

20. Residence Inn By Marriott St. Louis Clayton

Compare popular hotels close to James S. McDonnell Prologue Room

Top James S. McDonnell Prologue Room Hotel Reviews

Pear Tree Inn St. Louis Airport

Renaissance St. Louis Airport Hotel

La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North

Wingate by Wyndham St. Louis Airport

Hampton Inn By Hilton St Louis Airport

Hilton St. Louis Airport

Comfort Inn & Suites Hazelwood - St. Louis

Other attractions near James S. McDonnell Prologue Room

Blacks in Flight Mural

Payne-Gentry Historical House

Blanche M. Touhill Performing Arts Center

Old St. Ferdinand Shrine

St. Louis Mercantile Library

St. Louis Car Museum

St. Louis Kaplan Feldman Holocaust Museum

New Jewish Theatre

Frequently asked questions