The Best Hotels Closest to Maine Medical Center in Portland - 2026 Updated Prices

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Our top choices for Maine Medical Center hotels

A multi-story building with a stone facade, large windows, and a corner entrance.

A modern kitchen with a central island, wooden beams on the ceiling, and a dining area with a round table and chairs.

A modern living room with a large window, a sofa, a coffee table, a TV, and a brick wall.

A modern living room with a large window, a TV, a sofa, a coffee table, and a dining area with a brick wall.

1. Evalina Hotel

Old Port, 1.7 km from Maine Medical Center

Eric

Rp11.445.706

Rp15.139.519 total

includes taxes & fees

20 Oct - 21 Oct

A modern kitchen with a central island, bar stools, a dining table, and a built-in oven.

A room with a round wooden table, two chairs, a potted plant, a large window, and a round mirror on the wall.

A multi-story brick building with a modern design, featuring large windows and a flat roof.

2. The Weldon Hotel

Downtown Portland, 1.4 km from Maine Medical Center

Victoria

Rp7.168.656

Rp9.145.685 total

includes taxes & fees

18 Oct - 19 Oct

A modern bar area with a counter and stools, surrounded by patterned chairs and a blue sofa.

A hotel room with a bed, a small table, and a window with curtains.

A multi-story brick building with a flat roof, large windows, and outdoor seating areas.

3. Longfellow Hotel

Parkside, 0.3 km from Maine Medical Center

thomas

Rp6.696.542

Rp8.096.050 total

includes taxes & fees

27 Sept - 28 Sept

A brick building with a sign reading "WAYPOINT" and outdoor seating with tables, chairs, and a fire pit.

A spacious lobby with multiple seating areas, a fireplace, and large windows.

A chef in a black uniform and white hat, holding a ladle and a bowl, with various dishes in front of him.

A hotel room with two beds, a stone-patterned wall, and a nightstand with a lamp.

4. Embassy Suites by Hilton Portland Maine

2.9 km from Maine Medical Center

Peg

Rp4.069.473

Rp4.502.464 total

includes taxes & fees

27 Sept - 28 Sept

A balcony with a table and chairs, overlooking a street with buildings and parked cars.

A hot tub area with a tiled floor, a wooden bench, a potted plant, and towels on a rack.

A restaurant with a brick fireplace, white chairs, and tables set for dining.

A hotel with a prominent sign, a brick facade, and a street view with cars and pedestrians.

5. Portland Regency Hotel & Spa

Old Port, 1.8 km from Maine Medical Center

SHELBY

Rp6.052.810

Rp6.696.829 total

includes taxes & fees

18 Oct - 19 Oct

A living room with a grey sofa set, a wooden staircase, and a potted plant.

A balcony with a round table and orange chairs, overlooking a garden with various plants and flowers.

A reception area with a wooden desk, a fireplace, and a painting on the wall.

A historic brick building with a central entrance, a clock, and a well-maintained garden.

6. The Francis

Parkside, 0.3 km from Maine Medical Center

Jessica

Rp5.114.304

Rp6.107.331 total

includes taxes & fees

27 Sept - 28 Sept

A waterfront marina with boats docked, buildings with multiple windows, and a red building with a visible restaurant.

A hotel room with two beds, a desk, a TV, and a view of a body of water.

A spacious lobby with a high ceiling, large chandeliers, and a mix of seating areas including sofas and armchairs.

A hotel lobby with a bar area, seating arrangements, and a fireplace.

7. Hilton Garden Inn Portland Downtown Waterfront

Old Port, 2.1 km from Maine Medical Center

Jenna

Rp5.578.794

Rp6.172.385 total

includes taxes & fees

27 Sept - 28 Sept

A modern interior with a bar area, seating, and shelves with plants and books.

A cozy living room with a fireplace, two green armchairs, a coffee table, and a yellow ottoman.

A rooftop terrace with a sofa, two chairs, and a small table, overlooking a cityscape and a body of water.

A modern living room with a large sectional sofa, a dining area with a kitchen in the background, and large windows offering a city view.

8. The Press Hotel, Marriott Autograph Collection

Downtown Portland, 1.6 km from Maine Medical Center

Elizabeth

Rp8.416.645

Rp9.312.176 total

includes taxes & fees

18 Oct - 19 Oct

A modern bar area with a wooden bar counter, black bar stools, and a contemporary light fixture.

A black SUV parked in front of AC Hotel Portland, a modern building with a brick facade and large windows.

A modern reception area with a central desk, seating arrangements, and large windows offering views of the cityscape.

A hotel room with a large bed, a sofa, a small table, and a bench. There is a window with a view of the water.

9. AC Hotel Portland Downtown/Waterfront, ME

Downtown Portland, 2.3 km from Maine Medical Center

Paul

Rp5.479.029

Rp6.061.997 total

includes taxes & fees

18 Oct - 19 Oct

A rooftop terrace with a modern outdoor seating area, a fire pit, and a view of the cityscape.

A modern bar area with a long counter, multiple stools, and a variety of bottles and glasses on shelves.

A modern dining area with a dark blue booth seating, wooden ceiling beams, and large windows providing natural light.

A modern lobby with a geometric wall design, seating area, and a large abstract artwork.

10. Cambria Hotel Portland Downtown-Old Port

Downtown Portland, 2.3 km from Maine Medical Center

Rebecca

Rp4.492.447

Rp5.456.775 total

includes taxes & fees

18 Oct - 19 Oct

A modern bar area with a long counter, multiple seating options, and a built-in fire feature.

A conference room with a large screen displaying 'AFloat' and 'Holiday Inn by the bay'.

A Holiday Inn hotel with a modern design, featuring a large entrance canopy and multiple floors.

A modern bar area with seating and a bar counter.

11. Holiday Inn Portland-By the Bay by IHG

Portland Arts District, 1.2 km from Maine Medical Center

Zoe

Rp4.283.280

Rp4.739.021 total

includes taxes & fees

27 Sept - 28 Sept

A garden with a stone wall, various plants, and flowers.

A bathroom with wooden cabinetry, a sink, a mirror, and framed artwork on the wall.

A dining table set with a fruit bowl, cutlery, and decorative elements like a pumpkin and autumn leaves.

A two-story house with a porch and a sign reading "Fleetwork House."

12. Fleetwood House Bed & Breakfast

Rosemont, 2.7 km from Maine Medical Center

Karen

Rp4.066.582

Rp4.610.154 total

includes taxes & fees

4 Oct - 5 Oct

A balcony with wooden flooring, striped cushioned chairs, and a glass railing overlooking a cityscape at night.

A modern hotel with a dark facade, multiple windows, and a visible sign for 'Hyatt Place'.

A bar area with a polished granite countertop, a variety of liquor bottles, a fruit bowl, and blue upholstered bar stools.

A modern hotel room with a large bed, a desk, and a TV.

13. Hyatt Place Portland Downtown - Old Port Square

Old Port, 1.6 km from Maine Medical Center

Jeetindra

Rp5.336.253

Rp5.904.030 total

includes taxes & fees

27 Sept - 28 Sept

An outdoor patio area with wicker furniture, string lights, and a barbecue grill.

A hotel room with a bed, a TV, a nightstand, a window with a view of the water, and a wooden headboard.

A bar area with stools, a counter, and a herringbone-patterned wall.

A swimming pool with a tiled deck, lounge chairs, and a ceiling with recessed lighting.

14. Residence Inn by Marriott Portland Downtown/Waterfront

Downtown Portland, 2.3 km from Maine Medical Center

Greg

Rp4.533.138

Rp5.015.463 total

includes taxes & fees

18 Oct - 19 Oct

A spacious lounge with leather seating, round tables, and large windows offering a view of a body of water and buildings.

The exterior of the Westin hotel with a prominent entrance and two bicycles parked in front.

A modern hotel lobby with a large chandelier, reception desk, and a staircase leading to other areas.

A banquet hall with round tables, white tablecloths, and wooden chairs.

15. The Westin Portland Harborview

Downtown Portland, 0.9 km from Maine Medical Center

Richard

Rp4.533.138

Rp5.015.463 total

includes taxes & fees

27 Sept - 28 Sept

A multi-story building with a stone facade, multiple windows, and awnings.

A breakfast bar with various food items, a clock, and a mirror.

A hotel room with a bed, a desk, a lamp, a television, and a brick wall.

A sign for "The Inn at St. John" with a pineapple emblem.

16. Inn at St John Portland In-Town

Valley Street, 0.3 km from Maine Medical Center

Steve Robert

Rp2.262.107

Rp2.465.742 total

includes taxes & fees

28 Sept - 29 Sept

A multi-story hotel with 'Resilience Inn' and 'Mozy Hotels' signage, featuring a modern brick facade and multiple ground-level retail spaces.

A wooden bedside table with a classic rotary telephone and a textured wall-mounted lamp.

A modern hotel room with a large mirror, a wooden ceiling, and a patterned wall.

17. Moxy Portland Thompson's Point

1.4 km from Maine Medical Center

Brianna

Rp3.746.938

Rp4.145.612 total

includes taxes & fees

19 Oct - 20 Oct

A modern hotel lobby with a reception desk, a coffee station, and a tiled wall.

A modern living room with a fireplace, comfortable seating, and a flat-screen TV.

A hotel lobby with a sofa, chairs, a TV, and a breakfast sign.

18. La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

0.6 km from Maine Medical Center

Joseph

Rp2.356.696

Rp2.607.448 total

includes taxes & fees

18 Oct - 19 Oct

A spacious lobby with a sofa, chairs, a coffee table, and a TV.

An indoor swimming pool with clear lane markings, a seating area with chairs, and potted plants.

A bar area with wooden bar stools, a television, and a liquor display. There are red chairs and a small table with a glass top.

A lobby with a reception desk, a clock, a plant, and a round table.

19. Clarion Hotel Portland Airport ME

1.3 km from Maine Medical Center

Adam

Rp1.921.275

Rp2.125.698 total

includes taxes & fees

18 Oct - 19 Oct

A multi-story hotel with a modern brick facade, multiple ground-level retail spaces, and a neon sign indicating the hotel name.

A hotel room with two beds, a desk, a chair, a window with a view, and a framed picture on the wall.

A modern kitchen with a microwave, refrigerator, and a dining area with a table and chairs.

A bedroom with a bed, a grey sofa, a TV on a dresser, and two framed pictures on the wall.

20. Residence Inn by Marriott Portland Thompson's Point

1.4 km from Maine Medical Center

Thomas

Rp4.066.582

Rp4.499.266 total

includes taxes & fees

19 Oct - 20 Oct

View all properties

Compare popular hotels close to Maine Medical Center

Property	Property class	Guest rating
Evalina Hotel	10.0 Exceptional 11 reviews	View
The Weldon Hotel	9.8 Exceptional 119 reviews	View
Longfellow Hotel	9.6 Exceptional 192 reviews	View
Embassy Suites by Hilton Portland Maine	9.4 Exceptional 1,174 reviews	View
Portland Regency Hotel & Spa	9.4 Exceptional 1,735 reviews	View

Top Maine Medical Center Hotel Reviews

Hyatt Place Portland Downtown - Old Port Square

10/10 Excellent

"Hotel and room was very clean. Staff very helpful and attentive."

Portland Harbor Hotel

10/10 Excellent

"Great hotel with delicious breakfast."

Portland Regency Hotel & Spa

10/10 Excellent

"This hotel was right in the middle of Old Port and in such close proximity to all of the amazing restaurants and stores. The staff was incredibly attentive and so friendly. We never had to wait more than a couple minutes for anything. Even the restaurant and bar in the hotel was great and the food was delicious"

The Westin Portland Harborview

10/10 Excellent

"Very professional staffed Great amenities."

Longfellow Hotel

10/10 Excellent

"This hotel is amazing. Friendly staff- really good food and the spa was great."

Moxy Portland Thompson's Point

10/10 Excellent

"The staff was so nice and helpful and we were greeted by a lovely welcome cocktail! Highly recommend this stay."

The Francis

10/10 Excellent

"The Francis is an "old bones" hotel that has been updated to a 21st-century experience. The staff was attentive to our every need and up to date on the local area. The Hotel is just west of the Arts District and has many neighborhood restaurants within walking distance. The room was clean and comfortable and had a small reading area. The bathroom was modern and clean. Breakfast was delivered to our room in the morning from a local bakery. The room had a "pour-over" coffee pot with instructions that made some great coffee and an electric kettle for my wife to enjoy hot tea at any time of the day. Special shout-out to Devin at the front desk for his recommendations and assistance."

La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

10/10 Excellent

"We really enjoyed our stay here! Check-in was super easy, and we didn’t have to wait at all, which was a great start. The staff was so nice and welcoming, and our room was clean and looked just like the pictures online — always a plus! The breakfast provided was ample and had a fun make your own waffle station. I was a little surprised by the $10 parking fee, but I thought the $25 pet fee was very reasonable. Overall, we had a really nice experience and felt comfortable during our stay. I’d definitely stay here again!"

Aloft by Marriott Portland Downtown Waterfront ME

10/10 Excellent

"The hotel room was very comfortable, the beds were really nice, the layout of the bathroom was cool too. Great location. We didn't eat any of the breakfast stuff so can't comment on that."

Frequently asked questions

What's the area like around Maine Medical Center?

Maine Medical Center is located in a welcoming area of Portland known for its beautiful ocean views and sporting events. If you're looking for a convenient place to stay, take a look at the 194 hotels and other accommodation options you'll find within a mile.

What's the best place to stay close to Maine Medical Center?

Adjacent to Maine Medical Center, Inn at St John Portland In-Town is one of the top choices for your stay based on our traveller data, and this B&B offers free breakfast and free parking. Other good choices close by include Clarion Hotel Portland Airport ME and La Quinta Inn & Suites by Wyndham Portland DT/Maine Med.

How many hotels should I expect to find close to Maine Medical Center?

Expedia has 194 hotels and other accommodation options within a mile from Maine Medical Center.

If I need to cancel the hotel reservation for my stay near Maine Medical Center, will I receive a refund?

Yes, you'll find most hotel room reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best options available near Maine Medical Center.

What can I see and do near Maine Medical Center?

Portland Museum of Art, Maine Narrow Gauge Railroad and International Cryptozoology Museum feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like State Theatre, Victoria Mansion and Portland Head Light. You can watch performances at Merrill Auditorium, Port City Music Hall and Portland Stage if you're interested in local theatre.

Search Hotels Near Maine Medical Center, Portland

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for Maine Medical Center hotels

1. Evalina Hotel

2. The Weldon Hotel

3. Longfellow Hotel

4. Embassy Suites by Hilton Portland Maine

5. Portland Regency Hotel & Spa

6. The Francis

7. Hilton Garden Inn Portland Downtown Waterfront

8. The Press Hotel, Marriott Autograph Collection

9. AC Hotel Portland Downtown/Waterfront, ME

10. Cambria Hotel Portland Downtown-Old Port

11. Holiday Inn Portland-By the Bay by IHG

12. Fleetwood House Bed & Breakfast

13. Hyatt Place Portland Downtown - Old Port Square

14. Residence Inn by Marriott Portland Downtown/Waterfront

15. The Westin Portland Harborview

16. Inn at St John Portland In-Town

17. Moxy Portland Thompson's Point

18. La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

19. Clarion Hotel Portland Airport ME

20. Residence Inn by Marriott Portland Thompson's Point

Compare popular hotels close to Maine Medical Center

Top Maine Medical Center Hotel Reviews

Hyatt Place Portland Downtown - Old Port Square

Portland Harbor Hotel

Portland Regency Hotel & Spa

The Westin Portland Harborview

Longfellow Hotel

Moxy Portland Thompson's Point

The Francis

La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

Aloft by Marriott Portland Downtown Waterfront ME

Frequently asked questions