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Top Trending Hotels Near Mayo Clinic Florida

Lobby
Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic

4.5 star property
0.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (45)
"Beautiful hotel. Close to Mayo Clinic."
United States
Patty
The price is Rp2.035.885
Rp2.310.730 total
includes taxes & fees
23 Dec - 24 Dec
Hilton Jacksonville At Mayo Clinic
Terrace/patio
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

2.5 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1010)
"Spacious clean room, very quiet during our stay, friendly, helpful staff and breakfast was great."
United States
Joy
The price is Rp1.852.926
Rp2.103.071 total
includes taxes & fees
13 Dec - 14 Dec
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
Reception
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3.0 star property
1.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (444)
"Great facility to stay."
United States
Gary
The price is Rp2.395.364
Rp2.718.738 total
includes taxes & fees
19 Dec - 20 Dec
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Lobby sitting area
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

2.5 star property
2.7 km from Mayo Clinic Florida
8.6 out of 10, Excellent, (1017)
"We enjoyed the stay."
United States
Kenny
The price is Rp1.654.160
Rp1.877.473 total
includes taxes & fees
5 Dec - 6 Dec
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Terrace/patio
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

3.0 star property
0.3 km from Mayo Clinic Florida
8.4 out of 10, Very good, (751)
"Nice hotel, close to shops and mayo clinic."
United States
Judy
The price is Rp2.535.275
Rp2.877.538 total
includes taxes & fees
13 Dec - 14 Dec
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
On the beach, white sand, surfing, kayaking
Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

2.5 star property
5.9 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (3416)
"I had a great weekend stay on my birthday! "
United States
Adrian
Margaritaville Jacksonville Beach
Exterior
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

2.5 star property
4.2 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1018)
"Great location, very clean, kind staff. Would stay again if in area!"
United States
Justin
The price is Rp1.880.940
Rp2.134.867 total
includes taxes & fees
21 Dec - 22 Dec
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Free daily buffet breakfast
Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG

3.0 star property
4.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1003)
"The check in was simple and a room was ready for us before check out time. We were able to rest and sleep well during our stay in Jacksonville Beach."
United States
David
The price is Rp1.852.926
Rp2.103.071 total
includes taxes & fees
14 Dec - 15 Dec
Holiday Inn Express Jacksonville Beach by IHG
Lobby
Element Jacksonville Beach

Element Jacksonville Beach

3.0 star property
5.4 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (516)
"Clean room and friendly staff."
United States
Lucia
The price is Rp2.110.369
Rp2.395.268 total
includes taxes & fees
21 Dec - 22 Dec
Element Jacksonville Beach
BBQ/picnic Area
Salt Air Inn & Suites

Salt Air Inn & Suites

2.5 star property
7.8 km from Mayo Clinic Florida
9.8 out of 10, Exceptional, (402)
"A cute little gem with some of the best hospitality in the area. "
United States
Windy
Salt Air Inn & Suites
On the beach
Best Western Oceanfront

Best Western Oceanfront

3.0 star property
5.7 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1013)
"The room was clean and the bed was very comfortable! The view was beautiful! I will definitely stay here again in the future "
United States
Tinya
The price is Rp2.052.715
Rp2.329.832 total
includes taxes & fees
8 Dec - 9 Dec
Best Western Oceanfront
Sports facility
Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center

3.0 star property
Southside, 8.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1018)
"Always a great place to stay!"
United States
Richard
The price is Rp2.119.534
Rp2.405.671 total
includes taxes & fees
31 Dec - 1 Jan 2026
Hyatt Place Jacksonville / St. Johns Town Center
Exterior
Holiday Inn Jacksonville E 295 Baymeadows by IHG

Holiday Inn Jacksonville E 295 Baymeadows by IHG

3.0 star property
Deerwood, 8.5 km from Mayo Clinic Florida
8.6 out of 10, Excellent, (1009)
"Staf was very friendly housekeeping was very nice rooms clean"
United States
stacey
The price is Rp1.319.710
Rp1.497.870 total
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Jacksonville E 295 Baymeadows by IHG
Outdoor pool, open 8:00 AM to 8:00 PM, pool umbrellas, pool loungers
Seahorse Oceanfront Inn

Seahorse Oceanfront Inn

2.5 star property
8 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (595)
"Quintessential beachfront hotel with timeless setting. Close to great restaurants. We’ll be back."
United States
Keith
The price is Rp1.675.548
Rp1.901.747 total
includes taxes & fees
14 Dec - 15 Dec
Seahorse Oceanfront Inn
On the beach, windsurfing
Springhill Suites By Marriott Jacksonville Beach Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront

4.0 star property
5.8 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (617)
"Loved staying here. Great hotel. Very clean. The check-in process was smooth and Jay was awesome. I would recommend!"
United States
Kedric
The price is Rp2.534.600
Rp2.876.771 total
includes taxes & fees
21 Dec - 22 Dec
Springhill Suites By Marriott Jacksonville Beach Oceanfront
Exterior
Four Points by Sheraton Jacksonville Beachfront

Four Points by Sheraton Jacksonville Beachfront

3.0 star property
5.6 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1001)
"Easy to walk to the beach and local restaurant"
United States
Allen D
The price is Rp3.101.550
Rp3.520.259 total
includes taxes & fees
17 Dec - 18 Dec
Four Points by Sheraton Jacksonville Beachfront
2 outdoor pools, open 7:00 AM to 9:00 PM, pool umbrellas, pool loungers
Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront

3.0 star property
6.3 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (2584)
"We thoroughly enjoyed our stay! "
United States
Diane
The price is Rp2.119.534
Rp2.405.637 total
includes taxes & fees
23 Dec - 24 Dec
Hampton Inn Jacksonville Beach/Oceanfront
Exterior
Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

2.5 star property
Southside, 7.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (1024)
"East check in, clean room and very comfortable. Very convenient and comfortable for an overnight stop. Near shops and restaurant. "
United States
Cristina
The price is Rp1.879.586
Rp2.133.329 total
includes taxes & fees
14 Dec - 15 Dec
Holiday Inn Express & Suites Jacksonville - Town Center by IHG
Lobby
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

3.0 star property
8.5 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1031)
"Great stay!!!"
United States
Michael
The price is Rp2.040.051
Rp2.274.657 total
includes taxes & fees
21 Dec - 22 Dec
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
Exterior
Fairfield Inn & Suites by Marriott Jacksonville Beach

Fairfield Inn & Suites by Marriott Jacksonville Beach

2.5 star property
6.3 km from Mayo Clinic Florida
8.6 out of 10, Excellent, (887)
"Great place to stay highly recommend it"
United States
Taryn
The price is Rp1.899.282
Rp2.155.685 total
includes taxes & fees
7 Dec - 8 Dec
Fairfield Inn & Suites by Marriott Jacksonville Beach
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mayo Clinic Florida Hotel Reviews

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic

10/10 Excellent
"Beautiful hotel. Close to Mayo Clinic."
Patty 2-night trip
Posted 3 days ago
Hilton Jacksonville At Mayo Clinic

Hotels near other Mayo Clinic Florida attractions

Adventure Landing

4.1/5 (157 reviews)
This amusement park east of Jacksonville is a fun daytrip for the whole family with thrilling rides, exciting attractions for kids and a shipwreck-themed waterpark.
See properties

Windsor Parke Golf Club

Enjoy a round of golf in Jacksonville at Windsor Parke Golf Club. Amble around the area's beautiful beaches or attend a sporting event.
See properties

Frequently asked questions

What's the area like around Mayo Clinic Florida?
Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, take a look at the 41 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Mayo Clinic Florida?
Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices close by include Hilton Jacksonville At Mayo Clinic and Residence Inn By Marriott Jacksonville - Mayo Clinic Area.
How many hotels are there near Mayo Clinic Florida?
Expedia has 41 hotels and other accommodation options within a mile from Mayo Clinic Florida.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the top deals on offer near Mayo Clinic Florida.
What can I see and do near Mayo Clinic Florida?
You can enjoy live performances at Players by the Sea and Wilson Center For the Arts. Spend some time exploring the the natural beauty of Huguenot Park, Oceanfront Park and Cradle Creek Preserve. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.

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