Search Hotels Near Mayo Clinic Florida, Jacksonville

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Mayo Clinic Florida hotels

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
1.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (469 reviews)
"Clean room, amazing staff great location "
United States
Darlene
The price is Rp3.256.296
Rp3.695.895 total
includes taxes & fees
19 Mar - 20 Mar
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
0.8 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (162 reviews)
"Great place to stay"
United States
Judy
The price is Rp3.088.251
Rp3.505.166 total
includes taxes & fees
4 Apr - 5 Apr
Hilton Jacksonville At Mayo Clinic

TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East
3.0 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (585 reviews)
"Comfortable room, very nice staff. Great location."
United States
Andrew
The price is Rp2.074.764
Rp2.354.858 total
includes taxes & fees
29 Mar - 30 Mar
TownePlace Suites by Marriott Jacksonville East

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,002 reviews)
"Enjoyed the complimentary breakfast. "
United States
Andrew
The price is Rp1.922.615
Rp2.182.169 total
includes taxes & fees
22 Mar - 23 Mar
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
2.6 km from Mayo Clinic Florida
8.8 out of 10, Excellent, (1,007 reviews)
"Staff was nice and room was clean "
United States
Charles
The price is Rp2.041.512
Rp2.317.116 total
includes taxes & fees
4 Apr - 5 Apr
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
3.0 star property
0.4 km from Mayo Clinic Florida
8.4 out of 10, Very good, (765 reviews)
"Great location "
United States
Josiah Christine
The price is Rp3.322.996
Rp3.771.601 total
includes taxes & fees
27 Mar - 28 Mar
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Holiday Inn Express & Suites Jacksonville - Town Center by IHG
2.5 star property
Southside, 7.7 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (1,007 reviews)
"Great location, friendly staff, nice rooms, great breakfast."
United States
Michelle
The price is Rp2.210.232
Rp2.508.613 total
includes taxes & fees
30 Mar - 31 Mar
Holiday Inn Express & Suites Jacksonville - Town Center by IHG

TownePlace Suites by Marriott® Jacksonville Mayport

TownePlace Suites by Marriott® Jacksonville Mayport
3.0 star property
10.8 km from Mayo Clinic Florida
9.8 out of 10, Exceptional, (81 reviews)
"New, clean room and nice breakfast."
United States
Gregory
The price is Rp2.260.312
Rp2.565.453 total
includes taxes & fees
22 Mar - 23 Mar
TownePlace Suites by Marriott® Jacksonville Mayport

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
4.2 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,033 reviews)
"Clean room, good breakfast and location"
United States
Jesus
The price is Rp2.199.771
Rp2.496.741 total
includes taxes & fees
19 Mar - 20 Mar
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Ponte Vedra Inn & Club

Ponte Vedra Inn & Club
5.0 star property
6.3 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (815 reviews)
"Amazing. Loved it "
United States
Carol
The price is Rp10.947.332
Rp12.695.447 total
includes taxes & fees
17 Mar - 18 Mar
Ponte Vedra Inn & Club

The Lodge and Club at Ponte Vedra Beach

The Lodge and Club at Ponte Vedra Beach
5.0 star property
6.3 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (688 reviews)
"Clean room, excellent service and only steps from the ocean. The facility could use some TLC but, all in all, a wonderful place to stay. We’ll be back for sure. "
United States
Robert
The price is Rp10.103.932
Rp11.755.056 total
includes taxes & fees
19 Mar - 20 Mar
The Lodge and Club at Ponte Vedra Beach

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
5.9 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (3,715 reviews)
"Yes room was spotless and staff was amazing!"
United States
Martina
The price is Rp2.717.435
Rp3.084.482 total
includes taxes & fees
8 Mar - 9 Mar
Margaritaville Jacksonville Beach

AC Hotel Jacksonville St Johns Town Center

AC Hotel Jacksonville St Johns Town Center
2.5 star property
Southside, 8.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (180 reviews)
"Staff was excellent...highly recommend this Hotel"
Canada
Robert
The price is Rp3.526.248
Rp4.002.376 total
includes taxes & fees
3 Apr - 4 Apr
AC Hotel Jacksonville St Johns Town Center

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
5.7 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,013 reviews)
"Great location, breakfast was delicious "
United States
Paul
The price is Rp2.023.991
Rp2.297.253 total
includes taxes & fees
22 Mar - 23 Mar
Best Western Oceanfront

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.5 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,005 reviews)
"Very friendly staff, good restaurants in hotel and in the complex "
United States
Richard
The price is Rp2.807.847
Rp3.130.750 total
includes taxes & fees
22 Mar - 23 Mar
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Four Points by Sheraton Jacksonville Beachfront

Four Points by Sheraton Jacksonville Beachfront
3.0 star property
5.6 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,002 reviews)
"Beds very comfortable. Check-in seamless. I loved my stay."
United States
Pizza
The price is Rp3.424.204
Rp3.886.471 total
includes taxes & fees
22 Mar - 23 Mar
Four Points by Sheraton Jacksonville Beachfront

Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG
3.0 star property
4.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,005 reviews)
"Hotel was clean, breakfast was perfect."
United States
Kurt
The price is Rp2.209.708
Rp2.508.019 total
includes taxes & fees
22 Mar - 23 Mar
Holiday Inn Express Jacksonville Beach by IHG

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
Southside, 8.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,002 reviews)
"very friendly staff!! i love staying here!!"
United States
Evani
The price is Rp2.277.180
Rp2.584.599 total
includes taxes & fees
21 Mar - 22 Mar
Hyatt Place Jacksonville / St. Johns Town Center

Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront
3.0 star property
6.3 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (2,653 reviews)
"Everyone was friendly, kind and went out of their way to help with anything we needed. Great staff, great stay!"
United States
Barbara
The price is Rp2.891.861
Rp3.282.262 total
includes taxes & fees
22 Mar - 23 Mar
Hampton Inn Jacksonville Beach/Oceanfront

Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel
4.0 star property
Deerwood, 9.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,005 reviews)
"Beautiful property and great staff "
United States
Andrew
The price is Rp2.279.710
Rp2.587.471 total
includes taxes & fees
20 Mar - 21 Mar
Sheraton Jacksonville Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Mayo Clinic Florida Hotel Reviews

Hotels near other Mayo Clinic Florida attractions

Frequently asked questions

What's the area like around Mayo Clinic Florida?
Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, take a look at the 47 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Mayo Clinic Florida?
Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices close by include Hilton Jacksonville At Mayo Clinic and Residence Inn By Marriott Jacksonville - Mayo Clinic Area.
How many hotels are there near Mayo Clinic Florida?
Expedia has 47 hotels and other accommodation options within a mile from Mayo Clinic Florida.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the top deals on offer near Mayo Clinic Florida.
What can I see and do near Mayo Clinic Florida?
You can catch a show at SeaWalk Pavillion, Players by the Sea and SeaWalk Pavillion. Spend some time exploring the the natural beauty of Huguenot Park, Oceanfront Park and Cradle Creek Preserve. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.