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Our top choices for Oxbow Nature Center hotels

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Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
2.5 star property
14.4 km from Oxbow Nature Center
9.6 out of 10, Exceptional, (678)
"Good place to stay when traveling to Mayo apots"
United States
Carolyn
The price is Rp1.492.085
Rp1.717.761 total
includes taxes & fees
1 Jan - 2 Jan 2026
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Exterior
Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North
2.5 star property
11.4 km from Oxbow Nature Center
9.2 out of 10, Wonderful, (1002)
"Pool was nice "
Canada
Jesse
The price is Rp1.498.456
Rp1.725.096 total
includes taxes & fees
1 Jan - 2 Jan 2026
Hampton Inn & Suites Rochester-North
Terrace/patio
The Berkman

The Berkman

The Berkman
3.0 star property
15 km from Oxbow Nature Center
9.6 out of 10, Exceptional, (372)
"Staff was great, as was the room."
United States
Scott
The price is Rp2.804.952
Rp3.261.295 total
includes taxes & fees
27 Dec - 28 Dec
The Berkman
Property amenity
TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
15.9 km from Oxbow Nature Center
9.6 out of 10, Exceptional, (483)
"Room was large, clean, beds were comfortable. Downstairs cafe and seating areas were very comfortable."
United States
Ann
The price is Rp2.129.155
Rp2.451.189 total
includes taxes & fees
2 Jan - 3 Jan 2026
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Lobby
Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
3.5 star property
16.4 km from Oxbow Nature Center
9.6 out of 10, Exceptional, (547)
"Very courteous staff, loved the valet guy!"
United States
Jean
The price is Rp2.873.186
Rp3.307.755 total
includes taxes & fees
2 Jan - 3 Jan 2026
Hilton Rochester Mayo Clinic Area
Terrace/patio
Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
16.7 km from Oxbow Nature Center
9.6 out of 10, Exceptional, (884)
"Great stay,clean and friendly"
United States
Janet
The price is Rp1.910.875
Rp2.199.894 total
includes taxes & fees
1 Jan - 2 Jan 2026
Home2 Suites by Hilton Rochester Mayo Clinic Area
BBQ/picnic Area
Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South
3.0 star property
16.7 km from Oxbow Nature Center
9.6 out of 10, Exceptional, (254)
"Rooms were clean staff was courteous. "
United States
Michael
The price is Rp2.145.920
Rp2.470.490 total
includes taxes & fees
30 Dec - 31 Dec
Residence Inn by Marriott Rochester Mayo Clinic Area South
Courtyard
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
4.0 star property
15.3 km from Oxbow Nature Center
9.4 out of 10, Exceptional, (963)
"Rooms are comfortable and staff was was so professional and helpful."
United States
William
The price is Rp1.553.277
Rp1.821.739 total
includes taxes & fees
26 Dec - 27 Dec
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Suite, 1 King Bed with Sofa bed, Non Smoking (Efficiency, Upgrade) | Premium bedding, desk, blackout curtains, iron/ironing board
Sleep Inn & Suites West-Near Medical Center

Sleep Inn & Suites West-Near Medical Center

Sleep Inn & Suites West-Near Medical Center
2.5 star property
11.3 km from Oxbow Nature Center
9.0 out of 10, Wonderful, (584)
"Nice place to stay "
United States
Melissa
The price is Rp1.357.965
Rp1.563.357 total
includes taxes & fees
2 Jan - 3 Jan 2026
Sleep Inn & Suites West-Near Medical Center
Indoor spa tub
Comfort Inn & Suites West - Medical Center

Comfort Inn & Suites West - Medical Center

Comfort Inn & Suites West - Medical Center
3.0 star property
11.4 km from Oxbow Nature Center
9.0 out of 10, Wonderful, (527)
"Great stay at a great price"
United States
DAVID
The price is Rp1.406.919
Rp1.619.715 total
includes taxes & fees
25 Jan - 26 Jan 2026
Comfort Inn & Suites West - Medical Center
Courtyard
Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG
3.0 star property
15.3 km from Oxbow Nature Center
9.4 out of 10, Exceptional, (423)
"This was an amazing find in Rochester. Looking forward to staying here again. "
United States
Kellie
The price is Rp1.767.031
Rp2.067.824 total
includes taxes & fees
26 Dec - 27 Dec
Staybridge Suites Rochester - Mayo Clinic Area by IHG
Exterior
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3.0 star property
15 km from Oxbow Nature Center
9.2 out of 10, Wonderful, (771)
"Clean room and housekeeping service was excellent"
United States
Dawn
The price is Rp1.408.260
Rp1.621.259 total
includes taxes & fees
29 Dec - 30 Dec
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Terrace/patio
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
3.0 star property
15 km from Oxbow Nature Center
9.2 out of 10, Wonderful, (477)
"Clean room, breakfast selection"
United States
Sonya
The price is Rp1.837.841
Rp2.115.815 total
includes taxes & fees
28 Dec - 29 Dec
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
Terrace/patio
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
3.0 star property
16.1 km from Oxbow Nature Center
9.2 out of 10, Wonderful, (1001)
"Quick and easy check-in, walkable area and nice breakfast and accomodations. Would stay again!"
United States
Elizabeth
The price is Rp2.162.685
Rp2.489.791 total
includes taxes & fees
26 Dec - 27 Dec
Hyatt House Rochester/Mayo Clinic Area
2 indoor pools
TownePlace Suites by Marriott Rochester

TownePlace Suites by Marriott Rochester

TownePlace Suites by Marriott Rochester
3.0 star property
11.7 km from Oxbow Nature Center
8.8 out of 10, Excellent, (539)
"Hotel showed a lot of wear and tear. Front staff was helpful. "
United States
Heather
The price is Rp1.575.910
Rp1.814.267 total
includes taxes & fees
1 Jan - 2 Jan 2026
TownePlace Suites by Marriott Rochester
Fridge, microwave, oven, stovetop
Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham
3.0 star property
16.5 km from Oxbow Nature Center
9.2 out of 10, Wonderful, (167)
"Great staff, clean room, spacious kitchen and living room."
United States
silvia
The price is Rp2.598.575
Rp2.991.609 total
includes taxes & fees
26 Dec - 27 Dec
Broadway Plaza, Trademark Collection by Wyndham
Front of property
Aspen Suites

Aspen Suites

Aspen Suites
3.0 star property
15.1 km from Oxbow Nature Center
9.0 out of 10, Wonderful, (695)
"Room was clean and inviting and staff always willing to help"
United States
Maria del Carmen
The price is Rp2.601.817
Rp3.145.110 total
includes taxes & fees
9 Jan - 10 Jan 2026
Aspen Suites
Exterior
Candlewood Suites Rochester Mayo Clinic Area by IHG

Candlewood Suites Rochester Mayo Clinic Area by IHG

Candlewood Suites Rochester Mayo Clinic Area by IHG
2.5 star property
17.7 km from Oxbow Nature Center
9.2 out of 10, Wonderful, (454)
"The staff checking in and out were helpful and friendly. The room was clean, comfortable, and quiet. "
United States
Allison
The price is Rp1.626.205
Rp1.872.167 total
includes taxes & fees
5 Jan - 6 Jan 2026
Candlewood Suites Rochester Mayo Clinic Area by IHG
Exterior
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
2.5 star property
14.8 km from Oxbow Nature Center
8.8 out of 10, Excellent, (765)
"Clean room, friendly staff. The only minus is the lighting in the bathroom, way too dim. "
United States
Stacy
The price is Rp1.592.675
Rp1.833.567 total
includes taxes & fees
1 Jan - 2 Jan 2026
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Terrace/patio
Hampton Inn Rochester-South

Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.5 star property
17.8 km from Oxbow Nature Center
9.0 out of 10, Wonderful, (1001)
"We had a wonderful stay!"
United States
Sarah
The price is Rp1.350.950
Rp1.555.282 total
includes taxes & fees
24 Jan - 25 Jan 2026
Hampton Inn Rochester-South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Oxbow Nature Center Hotel Reviews

Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

10/10 Excellent
"Scrambled eggs, sausage, hard boiled eggs, fresh fruit, muffins, bagels nd more"
Elizabeth 1-night trip
Posted 13 days ago
Med City Inn & Suites - Mayo Clinic Area

Hotels near other Oxbow Nature Center attractions

Zollman Zoo

Visit the native and exotic animals who call Zollman Zoo home during your travels in Byron. Amble around the area's parks or experience its art scene.
See properties

Oxbow Park

Explore the great outdoors at Oxbow Park, a lovely green space in Byron. Visit the cosy cafes or top-notch restaurants in this walkable area.
See properties

Frequently asked questions

What's the area like around Oxbow Nature Center?
Oxbow Nature Center is located in Byron. When you want to settle in and find a place to stay, take a look at some of the hotels and other accommodation options that Expedia offers in the area.
What's the best place to stay close to Oxbow Nature Center?
Kahler Grand Hotel is one of the top choices for your stay based on our traveller data, and this hotel offers 2 restaurants and an indoor pool. You'll find it 10.1 mi (16.2 km) from Oxbow Nature Center. Other good choices around the area include Kahler Inn and Suites - Mayo Clinic Area and Hampton Inn & Suites Rochester-North.
If I need to cancel the hotel reservation for my stay near Oxbow Nature Center, will I receive a refund?
Yes, most hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best deals available near Oxbow Nature Center.
What can I see and do near Oxbow Nature Center?
If you're looking forward to a day of shopping, consider High Point Shopping Center, Byron Town Square and Cheery Meadows Center and pick out the perfect souvenir. Putting Green, Somerby Golf Club and Links of Byron Mini Golf are worth a stop while you're in the area. Zollman Zoo, Oxbow Park and Kalmar Town Hall are a few additional nearby sights.