A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

Panama City hotel guide. Four Seasons hotel in Panama City, Panamá Province

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
13 Nov - 15 Nov
In two weeks
20 Nov - 22 Nov
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Panama City Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

8/10 Good
"Amazing hotel. If you are interested in a buffet breakfast this is the hotel for you. The hotel was clean and the staff was friendly. It was also amazing to see a snackett open after hours. If you prefer to stay on property, you will have a variety of restaurants to choose from. Overall great hotel stay."
Vanisha 5-night trip
Posted 2 hours ago
Hotel Riu Plaza Panama