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Our top choices for Penrose hotels

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

1. Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park
3.5 star property
Dogtown, 6.5 km from Penrose
9.4 out of 10, Exceptional, (1,003 reviews)
"Nice hotel near WashUand Forest Park. It is clean and parking is easy."
United States
Edmond
The price is Rp2.357.922
Rp2.780.674 total
includes taxes & fees
16 Nov - 17 Nov
Hampton Inn & Suites St. Louis at Forest Park
A modern lobby with a staircase, seating area, and wall-mounted artwork.

2. Moonrise Hotel

Moonrise Hotel
4.0 star property
5.8 km from Penrose
9.0 out of 10, Wonderful, (2,059 reviews)
"Cool hotel!"
United States
Rebecca
The price is Rp2.519.240
Rp2.996.106 total
includes taxes & fees
24 Nov - 25 Nov
Moonrise Hotel
A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.

3. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End, 4.4 km from Penrose
9.2 out of 10, Wonderful, (1,008 reviews)
"The hotel is beautiful, and we really enjoyed the restaurants--The Tenderloin Room was especially delicious!"
United States
Sara
The price is Rp2.695.261
Rp3.711.759 total
includes taxes & fees
22 Nov - 23 Nov
The Royal Sonesta Chase Park Plaza St. Louis
An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

4. Home2 Suites by Hilton St. Louis/Forest Park

Home2 Suites by Hilton St. Louis/Forest Park
3.0 star property
The Grove, 5.5 km from Penrose
8.6 out of 10, Excellent, (1,001 reviews)
"Very nice place to stay."
United States
Ruth
The price is Rp2.598.485
Rp3.038.383 total
includes taxes & fees
6 Dec - 7 Dec
Home2 Suites by Hilton St. Louis/Forest Park
A modern living room with a fireplace, sofas, a coffee table, and a bookshelf.

5. AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End
4.0 star property
Central West End, 4.3 km from Penrose
9.0 out of 10, Wonderful, (863 reviews)
"Everything at this hotel was perfect. From the valet to the front desk to the breakfast were so friendly and nice. We will definitely stay here again. The location is also perfect"
United States
Janice
The price is Rp2.597.910
Rp3.063.688 total
includes taxes & fees
15 Nov - 16 Nov
AC Hotel St. Louis Central West End
A modern lobby with a large glass sphere, seating areas, and a reception desk.

6. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West, 6 km from Penrose
9.0 out of 10, Wonderful, (2,148 reviews)
"Wonderful Stay!"
United States
A.R.
The price is Rp2.598.091
Rp3.128.347 total
includes taxes & fees
7 Dec - 8 Dec
21C Museum Hotel St Louis
A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

7. Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
3.0 star property
13.3 km from Penrose
9.2 out of 10, Wonderful, (1,738 reviews)
"Near the airport; good breakfast."
United States
Cindy
The price is Rp1.829.724
Rp2.154.284 total
includes taxes & fees
24 Nov - 25 Nov
Wingate by Wyndham St. Louis Airport
An outdoor patio area with seating, planters, and a grill.

8. Element by Marriott St. Louis Midtown

Element by Marriott St. Louis Midtown
3.0 star property
Midtown, 4.8 km from Penrose
8.8 out of 10, Excellent, (856 reviews)
"Would stay again!"
United States
Julie
The price is Rp2.586.155
Rp3.023.965 total
includes taxes & fees
15 Nov - 16 Nov
Element by Marriott St. Louis Midtown
The exterior of the Charles F. Knight Center with a stone facade, large arched entrance, and a sign above the doors.

9. The Knight Center at Washington University

The Knight Center at Washington University
2.5 star property
7 km from Penrose
9.4 out of 10, Exceptional, (723 reviews)
"Perfect location. Beautiful hotel."
United States
April
The price is Rp2.476.560
Rp2.847.747 total
includes taxes & fees
24 Nov - 25 Nov
The Knight Center at Washington University
A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

10. Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
2.5 star property
12 km from Penrose
9.2 out of 10, Wonderful, (1,020 reviews)
"Loved my stay"
United States
Thadora
The price is Rp1.983.020
Rp2.458.666 total
includes taxes & fees
13 Nov - 14 Nov
Hyatt Select St. Louis Airport
An outdoor patio area with tables and chairs, string lights, and umbrellas.

11. Hotel Indigo St Louis - Central West End by IHG

Hotel Indigo St Louis - Central West End by IHG
3.5 star property
Central West End, 4.3 km from Penrose
8.8 out of 10, Excellent, (1,003 reviews)
"Great place, bar and food was excellent. Would definitely stay here again."
United States
Gordon
The price is Rp2.261.125
Rp2.864.957 total
includes taxes & fees
22 Nov - 23 Nov
Hotel Indigo St Louis - Central West End by IHG
Lobby

12. Drury Inn & Suites St. Louis Forest Park

Drury Inn & Suites St. Louis Forest Park
3.0 star property
8 km from Penrose
9.4 out of 10, Exceptional, (1,032 reviews)
"Loved staying there!"
United States
Tammy
The price is Rp2.441.294
Rp2.854.581 total
includes taxes & fees
15 Nov - 16 Nov
Drury Inn & Suites St. Louis Forest Park
An outdoor patio with a fire pit, seating, and a building in the background.

13. Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
9.9 km from Penrose
9.4 out of 10, Exceptional, (914 reviews)
"Beautiful accommodations! Helpful staff😊"
United States
Anna
The price is Rp2.137.215
Rp2.606.758 total
includes taxes & fees
22 Nov - 23 Nov
Courtyard by Marriott St. Louis Brentwood
A hotel room with two beds, a desk, a chair, and a television.

14. Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
9.1 km from Penrose
8.8 out of 10, Excellent, (3,532 reviews)
"Great location, nice rooms!"
United States
Martha
The price is Rp1.890.301
Rp2.206.699 total
includes taxes & fees
6 Dec - 7 Dec
Clayton Plaza Hotel & Extended Stay
A hot tub with a wooden deck, surrounded by a bamboo fence, and string lights.

15. The West End

The West End
2.0 star property
Central West End, 4.2 km from Penrose
8.6 out of 10, Excellent, (709 reviews)
"Excellent value, location. I'd stay here again."
United States
Trevor
The price is Rp1.266.456
Rp1.842.554 total
includes taxes & fees
15 Nov - 16 Nov
The West End
A grand building with a fountain in front.

16. The Cheshire

The Cheshire
4.0 star property
7.7 km from Penrose
8.8 out of 10, Excellent, (1,008 reviews)
"Fantastic hotel, clean and nice rooms, great breakfast and location"
United States
Matthew
The price is Rp2.695.388
Rp3.200.449 total
includes taxes & fees
29 Nov - 30 Nov
The Cheshire
A rooftop terrace with outdoor seating, string lights, and a city skyline view.

17. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
4.4 km from Penrose
8.8 out of 10, Excellent, (1,175 reviews)
"Loved the hotel!"
United States
Stephanie
The price is Rp1.868.349
Rp2.203.372 total
includes taxes & fees
24 Nov - 25 Nov
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
A lobby with a sofa, two armchairs, a coffee table, and a staircase.

18. Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 7.3 km from Penrose
8.6 out of 10, Excellent, (4,405 reviews)
"Great location and great place to visit"
United States
Tracy
The price is Rp2.035.012
Rp2.399.870 total
includes taxes & fees
27 Nov - 28 Nov
Hyatt Regency St. Louis at The Arch
A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

19. Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
13.3 km from Penrose
9.4 out of 10, Exceptional, (3,357 reviews)
"Great stay for airport access"
United States
Rebecca
The price is Rp1.627.469
Rp1.932.424 total
includes taxes & fees
15 Nov - 16 Nov
Pear Tree Inn St. Louis Airport
A modern hotel room with a large bed, a desk with a chair, a blue armchair, a sofa, a TV, and a large window offering a city view.

20. DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park
4.0 star property
Central West End, 4.8 km from Penrose
8.4 out of 10, Very good, (1,000 reviews)
"Parking was a bit confusing."
United States
Ronnie
The price is Rp2.594.112
Rp3.059.211 total
includes taxes & fees
16 Nov - 17 Nov
DoubleTree by Hilton St. Louis Forest Park
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Penrose

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A hot tub with a wooden deck, surrounded by a bamboo fence, and string lights.
The West End
2.0 star property
8.6
Excellent
709 reviews
View
An indoor pool area with a hot tub, seating, and a stone wall.
Drury Plaza Hotel St. Louis Union Station
3.0 star property
9.4
Exceptional
1,617 reviews
View
An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.
Hampton Inn & Suites St. Louis at Forest Park
3.5 star property
9.4
Exceptional
1,003 reviews
View
A modern lobby with a staircase, seating area, and wall-mounted artwork.
Moonrise Hotel
4.0 star property
9.0
Wonderful
2,059 reviews
View
Property amenity
Pear Tree Inn St. Louis Near Union Station
3.0 star property
8.8
Excellent
2,287 reviews
View

Where to stay in Penrose

Find the best Penrose areas for the activities you enjoy most.
The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Old Courthouse to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

A historic building with a green dome and adjacent modern high-rise buildings.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Top Penrose Hotel Reviews

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.
Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park
Dogtown

8/10 Good

Convenient location. Comfy beds.
United Kingdom
john
Reviewed September 21, 2025
Hampton Inn & Suites St. Louis at Forest Park

Frequently Asked Questions

What's it like in Penrose?

Travellers are sure to enjoy a stay in St. Louis's Penrose neighbourhood. Consider a visit to Julia Davis Branch Library as part of your Penrose travel plans.

If I need to cancel my hotel reservation in Penrose, will I receive a refund?

Yes! The majority of room reservations are refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If your reservation is non-refundable, you might still have the option to cancel and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then filter by "fully refundable" to get top deals in Penrose.

What is there to do around this St. Louis neighbourhood?

Julia Davis Branch Library is an attraction you might want to check out while you're in Penrose. Shelley House and Bellefontaine Cemetery are also worth a visit when you're out sightseeing in St. Louis.