Top Guest Houses in Pike County in 2026

A calm river surrounded by dense trees reflecting the greenery.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Next weekend

In two weeks

In one month

In two months

Our top choices for Pike County guest houses

A hotel room with a bed, two bedside lamps, a headboard, and a patterned carpet.

1. Riverside Inn Hannibal

Hannibal

Christina

Rp3.789.477 total

includes taxes & fees

11 Nov - 12 Nov

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Sign in

Sign up, it's free

Top Pike County Hotel Reviews

Bay Inn & Suites Troy

10/10 Excellent

"We were looking for a cheaper priced hotel as we were just stopping in for the night to sleep and getting on the road very early. Ironically, not realizing it, we had stayed at this hotel before. The hotel has done some really nice updates since our last visit, Hotel was clean, beds were comfortable and staff was friendly, We Walked and ate at a little Mexican restaurant that was close by, good food! Hotel is conveniently located to other restaurants as well. Would definitely not hesitate to stay here again."

Motel 6 Hannibal, MO

8/10 Good

"Great rate for a quick overnight stop. We didn't stay late enough for breakfast. The room was very clean, but the window latches were unlocked. I only noticed this because the curtain was open and I happened to notice as I was closing it. Our room was on the first floor and accessible from the parking lot through that window, so that was a little disconcerting. However, the front desk clerk got us checked in quickly, beds were comfy, and again the room was clean."