Search Hotels in San Isidro, Madrid

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
29 Dec - 30 Dec
Tomorrow
30 Dec - 31 Dec
This weekend
2 Jan - 4 Jan
Next weekend
9 Jan - 11 Jan

Filter by

Guest rating
Guest rating
Star rating

Our top choices for San Isidro hotels

Front of property
CIELO Madrid Studios

CIELO Madrid Studios

CIELO Madrid Studios
4.0 star property
San Isidro
9.0 out of 10, Wonderful, (357)
"It was a great stay even for few hours. We got there late and we had to leave early for our flight but everything was in order. Clean, easy access and the welcome kit. I’d definitely come stay there next time I’m in Madrid. Thank you "
United States
Otmane
CIELO Madrid Studios
Terrace/patio
Atipico Madrid

Atipico Madrid

Atipico Madrid
2.5 star property
Salamanca, 6.3 km from San Isidro
8.6 out of 10, Excellent, (138)
"Staff, facility, location."
United States
Cesar
The price is Rp1.738.168
Rp1.911.984 total
includes taxes & fees
7 Jan - 8 Jan 2026
Atipico Madrid
Porch
Hotel Riu Plaza España

Hotel Riu Plaza España

Hotel Riu Plaza España
4.0 star property
3.4 km from San Isidro
9.4 out of 10, Exceptional, (4559)
"Great staff, great location, really good breakfast buffet."
United States
Efrain
The price is Rp3.558.071
Rp3.913.878 total
includes taxes & fees
6 Jan - 7 Jan 2026
Hotel Riu Plaza España
Superior Double Room | In-room safe, soundproofing, iron/ironing board, free WiFi
B&B Hotel Madrid Centro F52

B&B Hotel Madrid Centro F52

B&B Hotel Madrid Centro F52
2.5 star property
Chueca, 3.8 km from San Isidro
9.4 out of 10, Exceptional, (550)
"Staff were very friendly and helpful. This location is close to all downtown areas."
United States
Afshin
The price is Rp1.564.384
Rp1.720.823 total
includes taxes & fees
6 Jan - 7 Jan 2026
B&B Hotel Madrid Centro F52
Lunch and dinner served
ICON Embassy

ICON Embassy

ICON Embassy
4.0 star property
Recoletos, 4.8 km from San Isidro
9.4 out of 10, Exceptional, (958)
"Staff were amazing. Great breakfast and unbeatable location"
United Kingdom
Maria
The price is Rp3.225.533
Rp3.548.087 total
includes taxes & fees
11 Jan - 12 Jan 2026
ICON Embassy
Premium bedding, Select Comfort beds, minibar, in-room safe
Barceló Torre de Madrid

Barceló Torre de Madrid

Barceló Torre de Madrid
5.0 star property
3.4 km from San Isidro
9.6 out of 10, Exceptional, (2283)
"Great hotel with polite and friendly staff "
United States
Conrad
The price is Rp3.660.981
Rp4.027.079 total
includes taxes & fees
11 Jan - 12 Jan 2026
Barceló Torre de Madrid
Classic Room, Terrace | Terrace/patio
H10 Puerta de Alcalá 4* Sup

H10 Puerta de Alcalá 4* Sup

H10 Puerta de Alcalá 4* Sup
4.0 star property
Recoletos, 4.9 km from San Isidro
9.2 out of 10, Wonderful, (1001)
"Clean room, the bar is excellent and the staff amazing!"
United States
Andres
The price is Rp2.225.618
Rp2.448.180 total
includes taxes & fees
18 Jan - 19 Jan 2026
H10 Puerta de Alcalá 4* Sup
Rooftop terrace
Room Mate Macarena, Madrid Gran Vía

Room Mate Macarena, Madrid Gran Vía

Room Mate Macarena, Madrid Gran Vía
3.0 star property
3.3 km from San Isidro
9.4 out of 10, Exceptional, (1326)
"Excellent location"
United States
Freddie
The price is Rp2.311.579
Rp2.542.796 total
includes taxes & fees
7 Jan - 8 Jan 2026
Room Mate Macarena, Madrid Gran Vía
Outdoor pool
SmartRental Collection Gran Vía Capital

SmartRental Collection Gran Vía Capital

SmartRental Collection Gran Vía Capital
4.0 star property
Chueca, 3.6 km from San Isidro
9.4 out of 10, Exceptional, (990)
"Very cleanly. The staff were magnificent. This location was super central and has great restaurants around "
United States
Jaqueline Aureola
The price is Rp2.808.902
Rp3.089.792 total
includes taxes & fees
7 Jan - 8 Jan 2026
SmartRental Collection Gran Vía Capital
Suite Exterior (Aduana) | Hypo-allergenic bedding, down duvets, Select Comfort beds, minibar
Hotel Regina

Hotel Regina

Hotel Regina
4.0 star property
Sol, 3.4 km from San Isidro
9.8 out of 10, Exceptional, (2227)
"Room amenities location and breakfast was amazing. Would definitely stay here again"
United States
Cindy
The price is Rp4.951.195
Rp5.446.315 total
includes taxes & fees
25 Jan - 26 Jan 2026
Hotel Regina
Breakfast, lunch, dinner served; local and international cuisine
Melia Barajas

Melia Barajas

Melia Barajas
4.0 star property
14.8 km from San Isidro
9.0 out of 10, Wonderful, (1983)
"Great staff, very accommodating... our goto hotel when traveling to Madrid!"
United States
Ann O'Ryan
The price is Rp2.186.213
Rp2.404.834 total
includes taxes & fees
10 Jan - 11 Jan 2026
Melia Barajas
Lobby
Hotel Nido Príncipe Pío

Hotel Nido Príncipe Pío

Hotel Nido Príncipe Pío
3.0 star property
2.8 km from San Isidro
8.8 out of 10, Excellent, (436)
"Great location very helpful staff, very clean and modern room"
Canada
iryna
The price is Rp1.429.037
Rp1.571.941 total
includes taxes & fees
7 Jan - 8 Jan 2026
Hotel Nido Príncipe Pío
Indoor pool, outdoor pool, open 4:00 PM to 8:00 PM, pool loungers
Hilton Madrid Airport

Hilton Madrid Airport

Hilton Madrid Airport
4.0 star property
Barajas, 13.5 km from San Isidro
9.0 out of 10, Wonderful, (1237)
"Great airport hotel with a suttle service, clean and confort good breakfast "
United Kingdom
Charbel
The price is Rp2.208.595
Rp2.429.454 total
includes taxes & fees
11 Jan - 12 Jan 2026
Hilton Madrid Airport
Spanish cuisine
Zleep Hotel Madrid Airport

Zleep Hotel Madrid Airport

Zleep Hotel Madrid Airport
3.0 star property
16.1 km from San Isidro
8.6 out of 10, Excellent, (2510)
"Great rooms and breakfast "
United States
James
The price is Rp1.057.258
Rp1.162.983 total
includes taxes & fees
4 Jan - 5 Jan 2026
Zleep Hotel Madrid Airport
Miscellaneous
Novotel Madrid Center

Novotel Madrid Center

Novotel Madrid Center
4.0 star property
Salamanca, 5.5 km from San Isidro
9.2 out of 10, Wonderful, (1032)
"Amazing stay"
United States
Diana
The price is Rp3.030.927
Rp3.334.019 total
includes taxes & fees
11 Jan - 12 Jan 2026
Novotel Madrid Center
Reception
Petit Palace President Castellana

Petit Palace President Castellana

Petit Palace President Castellana
4.0 star property
Recoletos, 5 km from San Isidro
8.2 out of 10, Very good, (1002)
"It was a great location and the room was good for 3"
United States
Giuliana
The price is Rp2.056.277
Rp2.261.905 total
includes taxes & fees
11 Jan - 12 Jan 2026
Petit Palace President Castellana
Property entrance
H10 Villa de la Reina Boutique Hotel

H10 Villa de la Reina Boutique Hotel

H10 Villa de la Reina Boutique Hotel
4.0 star property
Chueca, 3.5 km from San Isidro
9.0 out of 10, Wonderful, (1001)
"This was one of the best stays We have ever had. "
United States
Jeremyah
The price is Rp2.555.339
Rp2.810.873 total
includes taxes & fees
12 Jan - 13 Jan 2026
H10 Villa de la Reina Boutique Hotel
1 bedroom, minibar, in-room safe, desk
Room Mate Oscar, Madrid

Room Mate Oscar, Madrid

Room Mate Oscar, Madrid
3.0 star property
Chueca, 3.7 km from San Isidro
9.2 out of 10, Wonderful, (1007)
"This was a confortable hotel and very centrally located. "
United States
Hector L
The price is Rp2.311.579
Rp2.542.796 total
includes taxes & fees
11 Jan - 12 Jan 2026
Room Mate Oscar, Madrid
Daily buffet breakfast (EUR 18 per person)
Hotel Maydrit Airport

Hotel Maydrit Airport

Hotel Maydrit Airport
4.0 star property
13 km from San Isidro
9.4 out of 10, Exceptional, (2360)
"Loved our stay. "
United States
Toni
The price is Rp1.854.682
Rp2.040.151 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Maydrit Airport
Property entrance
One Shot Recoletos

One Shot Recoletos

One Shot Recoletos
4.0 star property
Recoletos, 4.2 km from San Isidro
9.2 out of 10, Wonderful, (94)
"Staff was really nice. Amazed at how big the gym is considering is such a tiny hotel. Location is great, quiet street."
United States
Ivelise
The price is Rp2.111.291
Rp2.322.420 total
includes taxes & fees
25 Jan - 26 Jan 2026
One Shot Recoletos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in San Isidro

Find the best San Isidro areas for the activities you enjoy most.

Madrid Centro

Known for its fascinating museums and acclaimed art galleries, there's plenty to explore in Madrid Centro. Check out top attractions like Gran Via and Puerta del Sol, and jump on the metro at Sol Station or Gran Via Station to see more of the city.

Sol

If you're spending time in Sol, check out sights like Gran Via or Puerta del Sol and hop on the metro to see more of the city at Sol Station or Callao Station.

Salamanca

Contemporary fashion, gourmet cuisine, fine art and upscale residential living await discovery in one of Madrid’s most stylish neighborhoods.

Ibiza

During your stop in Ibiza, check out the parks, and jump on the metro at Ibiza Station to see more of the surrounding area.

Chueca featuring café lifestyle and a city as well as a large group of people

Chueca

This avant-garde part of Madrid is known as the gay quarter because of its numerous LGBT shops and bars, a Gay Pride march and an open-minded populace.

Top San Isidro Hotel Reviews

Hotel Emperador

Hotel Emperador

10/10 Excellent
"Very clean, nice staff great breakfast. Everything in point"
Michelle 2-night trip
Posted 5 days ago
Hotel Emperador

Frequently asked questions

What is San Isidro like?
Travellers to the San Isidro neighbourhood in Madrid will be sure to enjoy their stay. Consider a visit to Ermita de San Isidro as part of your San Isidro travel plans.
How many hotels will I be able to find in the San Isidro area?
If you're searching for places to stay in Madrid, choose from one of Expedia's 13 hotels and other accommodation options in San Isidro.
If I need to cancel my hotel reservation in San Isidro, will I receive a refund?
Yes! The majority of hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to view the top deals on offer in San Isidro.
What is there to do in this Madrid neighbourhood?
Ermita de San Isidro is an attraction you might want to check out while you're in San Isidro. While you're out sightseeing in Madrid, make sure that you visit other sights such as Gran Via or Plaza Mayor.
How can I get around San Isidro and the greater Madrid area?
Ready to get out and explore the city? Marques de Vadillo Station is the closest metro station.

Explore a world of travel with Expedia