Find hotels in Santa Cruz from Rp1.339.833

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
26 Dec - 27 Dec
Tomorrow
27 Dec - 28 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Cruz hotels

Bar (on property)
La Morada Tepotzotlan Boutique & Spa

La Morada Tepotzotlan Boutique & Spa

La Morada Tepotzotlan Boutique & Spa
3.5 star property
Tepotzotlán
8.0 out of 10, Very good, (40)
Escape to this tranquil Mexico retreat with 2 hot tubs and an outdoor pool. Unwind with hot stone massages at the full-service spa, enjoy a meal at the restaurant, or sip drinks at the bar. Nearby attractions include Hacienda La Concepcion and the Artisan Market.
"na"
Mexico
Karina Ponce
La Morada Tepotzotlan Boutique & Spa
Property grounds
Hotel Finca Las Hortensias

Hotel Finca Las Hortensias

Hotel Finca Las Hortensias
3.0 star property
Tepotzotlán
8.4 out of 10, Very good, (185)
Immerse in the charm of Tepotzotlán at this welcoming hotel featuring an outdoor pool with dedicated children's area. Los Girasoles restaurant serves Mexican cuisine, while the bar offers refreshing drinks. Near Artisan Market and National Museum of the Viceroyalty.
"Hortencias a fantastic place to relax on a family envornment , close to nature and outstanding sercvice"
United States
Jerry C.
The price is Rp1.006.979
Rp1.208.375 total
includes taxes & fees
28 Dec - 29 Dec
Hotel Finca Las Hortensias
Terrace/patio
Fiesta Americana México Satélite

Fiesta Americana México Satélite

Fiesta Americana México Satélite
4.5 star property
Tlalnepantla de Baz
9.4 out of 10, Exceptional, (763)
Luxurious accommodation near Plaza Satelite Shopping Centre, featuring international cuisine at MOXAICO restaurant and a stylish bar. Fitness enthusiasts will appreciate the modern centre while all guests enjoy the free shuttle and helpful staff.
"nice hotel and great location "
United States
karen
The price is Rp1.757.805
Rp2.109.366 total
includes taxes & fees
27 Dec - 28 Dec
Fiesta Americana México Satélite
Junior Room | Premium bedding, down duvets, in-room safe, individually decorated
St Isidro Suites Corporate Housing SPA & Wellness Center

St Isidro Suites Corporate Housing SPA & Wellness Center

St Isidro Suites Corporate Housing SPA & Wellness Center
4.0 star property
Miguel Hidalgo
9.2 out of 10, Wonderful, (1004)
Indulge in hot stone massages at this wellness-focused retreat near Paseo de la Reforma. Enjoy the health club, bar, and Raíces mx restaurant serving three meals daily. Rooms offer refrigerators and microwaves, plus free WiFi, valet parking, and area shuttle.
"Great room and nice restaurant for all day meals"
United States
Fan
St Isidro Suites Corporate Housing SPA & Wellness Center
The Royalty Suite | Egyptian cotton sheets, premium bedding, minibar, in-room safe
UTOPIC Campos Elíseos by ULIV

UTOPIC Campos Elíseos by ULIV

UTOPIC Campos Elíseos by ULIV
4.0 star property
Polanco
9.4 out of 10, Exceptional, (653)
Luxurious Mexico City retreat near Auditorio Nacional with free breakfast and WiFi. Relax with deep-tissue massages after exploring Angel of Independence Monument and Chapultepec Park. Just 9 minutes from Auditorio Station in the vibrant Campos Elíseos area.
"Nice, boutique Hotel! Clean y great staff"
United States
Brenda
UTOPIC Campos Elíseos by ULIV
Standard Double Suite | City view
UTOPIC Polanco by ULIV

UTOPIC Polanco by ULIV

UTOPIC Polanco by ULIV
4.5 star property
Miguel Hidalgo
9.0 out of 10, Wonderful, (749)
Discover luxury living at this aparthotel with premium bedding, rainfall showers, and espresso makers in every unit. The rooftop terrace offers city views while Chapultepec Station is just a 15-minute walk. Guests love the helpful staff and clean, well-appointed spaces.
"We had a great stay. Area was safe to walk around, and hotel was near tourist attractions. "
United States
Guadalupe
UTOPIC Polanco by ULIV
Two-Bedroom Apartment with Huge Private Patio | Terrace/patio
ULIV Parque Lincoln

ULIV Parque Lincoln

ULIV Parque Lincoln
3.5 star property
Polanco
9.6 out of 10, Exceptional, (845)
Stylish apartment-style living with premium bedding and rainfall showers in Mexico City's vibrant Polanco area. The rooftop terrace offers a perfect retreat after exploring nearby Angel of Independence Monument. Free WiFi and fitness centre enhance your stay.
"This was an exceptional place to stay, close to best dinning options and shopping, one of the safest areas in Mexico City being honest."
United States
Nissim
ULIV Parque Lincoln
Deluxe Double Room, 1 King Bed | Premium bedding, down duvets, in-room safe, laptop workspace
Ana Polanco Apartments

Ana Polanco Apartments

Ana Polanco Apartments
3.5 star property
Polanco
9.8 out of 10, Exceptional, (184)
Immerse yourself in Mexico City from this stylish retreat. Located a short walk from Paseo de la Reforma and Chapultepec Park, the apartments offer rainfall showers, down comforters, and 24-hour fitness centre access. Angel of Independence Monument sits nearby.
"Great place! Super quiet area. Confortable bed. I would definitely stay here again. Great communication with host"
United States
Guillermo
The price is Rp1.989.327
Rp2.407.085 total
includes taxes & fees
28 Dec - 29 Dec
Ana Polanco Apartments
3 restaurants, breakfast, lunch, dinner served; Latin American cuisine
Hyatt Regency Mexico City

Hyatt Regency Mexico City

Hyatt Regency Mexico City
5.0 star property
Polanco
9.4 out of 10, Exceptional, (1342)
Immerse in Mexico City's culture from this spa hotel, just minutes from Auditorio Nacional and Paseo de la Reforma. Enjoy Latin American cuisine at RULFO, 1 of 3 restaurants, then admire mountain views after a refreshing swim.
"Great stay"
United States
Carlos
The price is Rp3.799.370
Rp4.540.247 total
includes taxes & fees
17 Jan - 18 Jan 2026
Hyatt Regency Mexico City
Superior Room King | In-room safe, desk, iron/ironing board, free cots/infant beds
Fiesta Inn Express Naucalpan

Fiesta Inn Express Naucalpan

Fiesta Inn Express Naucalpan
3.5 star property
Naucalpan
8.6 out of 10, Excellent, (947)
Enjoy complimentary valet parking, WiFi, and daily buffet breakfast at this convenient Naucalpan hotel. Work out in the fitness centre before exploring nearby attractions like Paseo de la Reforma and Plaza Satelite Shopping Centre.
"Great room and staff."
United States
Juan
The price is Rp1.546.868
Rp1.856.242 total
includes taxes & fees
27 Dec - 28 Dec
Fiesta Inn Express Naucalpan
Exterior
InterContinental Presidente Mexico City by IHG

InterContinental Presidente Mexico City by IHG

InterContinental Presidente Mexico City by IHG
4.0 star property
Polanco
9.4 out of 10, Exceptional, (2110)
"The best place to stay! "
United States
Mario Perez
The price is Rp3.998.588
Rp4.778.384 total
includes taxes & fees
2 Jan - 3 Jan 2026
InterContinental Presidente Mexico City by IHG
Hypo-allergenic bedding, in-room safe, individually decorated
Kukun Homero Polanco

Kukun Homero Polanco

Kukun Homero Polanco
4.0 star property
Polanco
9.4 out of 10, Exceptional, (223)
Escape to this stylish Mexico City retreat featuring a fitness centre and free WiFi. Just 10 minutes from Polanco Station and a short drive to the iconic Angel of Independence Monument, these smart apartments offer private balconies for urban relaxation.
"Loved the view from the balcony and very friendly staff. "
United States
Claudia
The price is Rp1.805.117
Rp2.184.192 total
includes taxes & fees
6 Jan - 7 Jan 2026
Kukun Homero Polanco
Lobby
Fiesta Americana México Toreo

Fiesta Americana México Toreo

Fiesta Americana México Toreo
4.0 star property
Naucalpan
9.6 out of 10, Exceptional, (1004)
Experience stylish comfort at this modern hotel featuring an indoor pool and health club. Located just 5 minutes from Paseo de la Reforma and Toreo Parque Central, with international cuisine at MOXAICO COCINA LOCAL and 24-hour room service for convenience.
"It was a wonderful stay"
United States
Lukas
The price is Rp2.660.145
Rp3.192.174 total
includes taxes & fees
27 Dec - 28 Dec
Fiesta Americana México Toreo
Terrace/patio
Las Suites Campos Eliseos

Las Suites Campos Eliseos

Las Suites Campos Eliseos
4.0 star property
Polanco
9.2 out of 10, Wonderful, (1356)
Immerse yourself in Mexico City's upscale Campos Eliseos area. This hotel offers complimentary breakfast, WiFi, and parking, plus a health club and restaurant. The spa provides deep-tissue massages near Chapultepec Park and the Angel of Independence Monument.
"The staff was top notch"
United States
Alan
The price is Rp2.533.770
Rp3.027.855 total
includes taxes & fees
18 Jan - 19 Jan 2026
Las Suites Campos Eliseos
Rooftop terrace
ULIV Apartments Polanco

ULIV Apartments Polanco

ULIV Apartments Polanco
4.0 star property
Miguel Hidalgo
8.8 out of 10, Excellent, (304)
Walking distance to Polanco Station, this aparthotel offers stylish accommodation with smart TVs and rainfall showers. Enjoy the fitness centre after exploring nearby Paseo de la Reforma. Free parking and WiFi add convenience for Mexico City adventures.
"Easy check in and out and a great apartment "
Canada
Jose
ULIV Apartments Polanco
Superior Studio Suite, 1 King Bed, Balcony | Balcony
Lamartine Boutique Hotel Polanco

Lamartine Boutique Hotel Polanco

Lamartine Boutique Hotel Polanco
5.0 star property
Polanco
9.2 out of 10, Wonderful, (64)
Luxurious retreat near Polanco Station offers free breakfast and WiFi just minutes from Paseo de la Reforma. Enjoy deep-tissue massages after a workout in the 24-hour gym, then relax on the terrace or grab a bite at the café.
"Our stay here was excellent, the staff were lovely and the room was comfortable.."
United States
Michael
The price is Rp4.285.696
Rp5.121.406 total
includes taxes & fees
2 Jan - 3 Jan 2026
Lamartine Boutique Hotel Polanco
Interior
Casa Olea

Casa Olea

Casa Olea
2.0 star property
Downtown Mexico City
9.4 out of 10, Exceptional, (649)
Experience Casa Olea's ideal location just a 5-minute drive from Paseo de la Reforma and Angel of Independence Monument. Enjoy complimentary WiFi and parking while being near Palacio de Bellas Artes. Normal Station is a 13-minute stroll away for easy city exploration.
"Great room, helpful staff, wonderful location - this will definitely be a go to spot for trips to come. "
United States
Jazmyn
The price is Rp1.121.199
Rp1.339.833 total
includes taxes & fees
12 Jan - 13 Jan 2026
Casa Olea
30-inch TV with satellite channels
W Mexico City

W Mexico City

W Mexico City
5.0 star property
Polanco
8.8 out of 10, Excellent, (1001)
"Great Hotel"
United States
Rachel
The price is Rp4.539.322
Rp5.424.490 total
includes taxes & fees
19 Jan - 20 Jan 2026
W Mexico City
Interior entrance
FlowSuites Polanco

FlowSuites Polanco

FlowSuites Polanco
3.5 star property
Polanco
8.4 out of 10, Very good, (393)
"Great location, and very friendly staff. The room was a bit dark and didn't have all the bathroom amenities filled. (e.g. shower soap). "
United States
Nicolas
The price is Rp2.072.804
Rp2.477.001 total
includes taxes & fees
29 Dec - 30 Dec
FlowSuites Polanco
Exterior
Suites Teca Once

Suites Teca Once

Suites Teca Once
3.5 star property
Naucalpan
7.4 out of 10, Good, (289)
Enjoy business-friendly accommodation minutes from Paseo de la Reforma and Centro Citibanamex Convention Centre. Work out anytime in the 24-hour fitness centre. Angel of Independence Monument and convenient transit options at Polanco Station are nearby.
"Todo excelente "
Mexico
J
The price is Rp893.972
Rp1.072.766 total
includes taxes & fees
27 Dec - 28 Dec
Suites Teca Once
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santa Cruz Hotel Reviews

Casa Olea

Casa Olea

10/10 Excellent
"Great staff and the room was very clean and looked really good Wonderful amenities too! "
Takura 5-night trip
Posted 3 days ago
Casa Olea
Collection O Hotel Lavanda Anzures

Collection O Hotel Lavanda Anzures

10/10 Excellent
"The room was basic but very nice and the location is the best for dinning out and shopping. Very well located to walk to many attractions "
James 3-night trip
Posted 2 weeks ago
Collection O Hotel Lavanda Anzures

More cheap stays in Santa Cruz

Casa Olea

Casa Olea

C. de Francisco Díaz Covarrubias Mexico City CDMX
The price is Rp1.121.199 per night from 12 Jan to 13 Jan
Rp1.121.199
Rp1.339.833 total
12 Jan - 13 Jan 2026
includes taxes & fees
9.4/10 Exceptional! (645 reviews)

Frequently asked questions

Where is the best place for a stay in Santa Cruz?
Located 18.9 mi (30.5 km) from the heart of Santa Cruz, Hyatt Regency Mexico City is a top choice for your stay, based on our traveller data. Two other choices for your stay in the area are InterContinental Presidente Mexico City by IHG and Downtown Treasure Place. See all available top hotels, or vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
What is staying in Santa Cruz like?
Those travelling to Santa Cruz will definitely enjoy the sights to see and things to do. In Santa Cruz, there are 2 hotels and other accommodation options to choose from. Find out more about Santa Cruz.
What are the top places to visit in Santa Cruz?
Places to visit in the wider area include Hacienda La Concepcion, National Museum of the Viceroyalty and San Marcos Power Center. You'll also find Xochitla Ecological Park and Arcos del Sitio in the area. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.
What's the seasonal weather like in Santa Cruz?
The hottest months are usually April and May, with an average temperature of 18°C, while the coldest months are January and December, with an average of 14°C. The rainiest months in Santa Cruz are August, July, September and June, with each month seeing an average of 186 mm of rainfall.

Explore a world of travel with Expedia