A flooded area with trees standing in water.

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Check prices for these dates

Tonight
23 Sept - 24 Sept
Tomorrow
24 Sept - 25 Sept
This weekend
25 Sept - 27 Sept
Next weekend
2 Oct - 4 Oct

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Our top choices for Santee National Wildlife Refuge hotels

A tent with a view of a lake and boats, a wooden chair, and a potted plant.
A compact living space with a bunk bed, a kitchenette, and a control panel with a clock.
A modern room with a grey sofa, a small table, and a view of a lake and parked car through large glass doors.
A modern, two-story mobile home with a metal exterior, large windows, and a visible kitchen area.

1. Bells Marina & Resort

Bells Marina & Resort
19.5 km from Santee National Wildlife Refuge
United States
Mark
Rp1.462.328
Rp1.676.725 total
includes taxes & fees
24 Sept - 25 Sept
Bells Marina & Resort
A hotel room with a bed, a black armchair, a round mirror with lights, a black vanity with a sink, and a white towel on the wall.
A building with a red roof and a covered entrance area. There are cars parked in front.
A modern room with a grey sofa, a small table, and a black countertop with a sink.
A bathroom with a textured wall, a round mirror with a light, a black countertop, and a white sink.

2. Starlight Stays

Starlight Stays
19.8 km from Santee National Wildlife Refuge
United States
tevin
Rp1.207.170
Rp1.339.960 total
includes taxes & fees
22 Oct - 23 Oct
Starlight Stays
A hotel dining area with multiple tables and chairs, a large flat-screen TV, and a patterned wall design.
A modern hotel with a swimming pool, outdoor seating, and a sign reading "Hampton Inn".
A hotel room with a bed, desk, chair, lamp, kitchenette, and a door.
A gym with treadmills, weight machines, and a wall of dumbbells.

3. Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
7 km from Santee National Wildlife Refuge
United States
Herbert
Rp2.259.430
Rp2.507.967 total
includes taxes & fees
15 Oct - 16 Oct
Hampton Inn Santee-I-95
A patio area with wicker furniture, a stone fire pit, and outdoor seating.
A modern living room with a stone wall, a flat-screen TV, a fireplace, and a dining area with a round table and chairs.
A multi-story hotel with a prominent sign, a covered entrance, and a parking lot.
A reception desk with a wooden panel wall and a circular decorative piece above it.

4. Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
7 km from Santee National Wildlife Refuge
United States
Melissa
Rp2.398.244
Rp2.662.053 total
includes taxes & fees
30 Sept - 1 Oct
Fairfield Inn & Suites by Marriott Santee
A breakfast area with a self-service counter, refrigerated display, and a digital menu board.
A hotel room with two beds, a desk, and a large window with a view.
A modern hotel with a blue and white facade, a covered entrance, and palm trees in front.
A modern lobby with a blue sofa, teal chairs, and a wooden table.

5. Tru By Hilton Santee

Tru By Hilton Santee
7.2 km from Santee National Wildlife Refuge
United States
Connor
Rp1.847.775
Rp2.051.032 total
includes taxes & fees
18 Oct - 19 Oct
Tru By Hilton Santee
A buffet with various food items and utensils.
A stone building with a sign for George's Oriental Restaurant & Ice.
A room with a patterned carpet, two potted plants, a wooden shelf with books, and a door with a sign.
A reception area with a counter, a clock, a ceiling fan, and a potted plant.

6. Sunset Inn Manning I 95

Sunset Inn Manning I 95
18.9 km from Santee National Wildlife Refuge
United States
James
Rp840.906
Rp1.017.421 total
includes taxes & fees
30 Sept - 1 Oct
Sunset Inn Manning I 95
A hotel entrance with a sign reading "Best Western PLISS."
A modern kitchen with a red accent wall, white cabinetry, and a built-in espresso machine.
A spacious living room with a large window, a ceiling fan, and a vibrant red accent wall.
A hotel room with two large beds, a wooden headboard, bedside tables with lamps, a wardrobe, and a view of the outdoors through a window.

7. Best Western Plus Santee Inn

Best Western Plus Santee Inn
7 km from Santee National Wildlife Refuge
United States
Donna
Rp2.128.196
Rp2.362.297 total
includes taxes & fees
5 Oct - 6 Oct
Best Western Plus Santee Inn
A hotel room with two beds, a grey armchair, a nightstand with a phone, and a cityscape picture on the wall.
A lobby with two leather armchairs, a marble-topped table, and a patterned carpet.
A Baymont by Wyndham hotel with a blue and yellow facade, a covered parking area, and a large parking lot.
A hotel corridor with blue doors, a covered walkway, and a parking lot in the background.

8. Baymont by Wyndham Santee

Baymont by Wyndham Santee
7.2 km from Santee National Wildlife Refuge
United States
Yomerys
Rp1.430.541
Rp1.587.900 total
includes taxes & fees
24 Sept - 25 Sept
Baymont by Wyndham Santee
A hotel room with a large bed, a desk, a chair, a desk lamp, and a wall-mounted lamp.
A modern living room with a sofa, a red ottoman, a TV mounted on the wall, and a wooden entertainment unit.
A spacious lobby with a modern staircase, seating area with orange and teal chairs, and a fireplace.
A modern living room with teal and orange chairs, a grey sofa, a fireplace, and a staircase.

9. Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
7.2 km from Santee National Wildlife Refuge
United States
santa
Rp1.881.074
Rp2.087.993 total
includes taxes & fees
13 Oct - 14 Oct
Comfort Inn & Suites Santee
A water park with a pool, slides, and umbrellas.
A cobblestone street lined with colorful buildings, a palm tree, and flowering trees.
A reception desk with a wooden panel backdrop and a neon sign.
A hotel room with two beds, a desk, a chair, a TV, and a large window with curtains.

10. Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
7.2 km from Santee National Wildlife Refuge
United States
Dennis
Rp1.784.700
Rp1.981.017 total
includes taxes & fees
18 Oct - 19 Oct
Holiday Inn Santee by IHG
A hotel room with two beds, a desk, a mirror, and a wall-mounted TV.
A room with a flat-screen TV mounted on the wall, a small round table with a computer and keyboard, a chair, and a framed picture above the table.
A motel with a brick facade, a covered entrance, and a satellite dish.
A bathroom with a granite countertop, a sink, a mirror, and a light fixture above the mirror.

11. Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
7.1 km from Santee National Wildlife Refuge
United States
Kunjan
Rp1.142.208
Rp1.267.852 total
includes taxes & fees
4 Oct - 5 Oct
Travelodge by Wyndham Santee
A dining area with multiple tables and chairs, a ceiling fan, and large windows.
A reception area with a marble counter, a television, and a logo for 'Superstart breakfast'.
A swimming pool with lounge chairs and umbrellas, surrounded by a fence and a building with large windows.
A hotel room with two beds, a desk, a chair, a lamp, and a window with curtains.

12. Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95
7 km from Santee National Wildlife Refuge
United States
William
Rp1.137.746
Rp1.262.898 total
includes taxes & fees
4 Oct - 5 Oct
Super 8 by Wyndham Santee/I-95
A church with a triangular roof, a central entrance, and a bell tower.
A hotel reception area with a wooden reception desk, a digital screen displaying 'Free Wi-Fi All Rooms,' and a 'Red Roof Inn' sign on the wall.
A hotel room with a television mounted on the wall displaying a sports game, a desk with a lamp, a chair, and a refrigerator.
A hotel room with a bed, a desk, a chair, a door, and a window with curtains.

13. Red Roof Inn Santee

Red Roof Inn Santee
7 km from Santee National Wildlife Refuge
United States
Tiffany
Rp1.124.201
Rp1.247.863 total
includes taxes & fees
4 Oct - 5 Oct
Red Roof Inn Santee
A hotel room with two beds, a desk, a chair, a lamp, and a window with curtains.
A building with a red roof, a yellow door, and a brick facade.
A bathroom with a sink, mirror, and a shower area.
A reception area with a counter, framed pictures, and a clock on the wall.

14. Econo Lodge Santee

Econo Lodge Santee
7.1 km from Santee National Wildlife Refuge
United States
Dorothy
Rp1.138.674
Rp1.263.929 total
includes taxes & fees
19 Oct - 20 Oct
Econo Lodge Santee
A modern kitchen with dark cabinets, a granite countertop, a ceiling fan, a flat-screen TV, and a breakfast bar with pastries.
A living room with a brown sofa set, a wooden coffee table, and a chandelier.
A spacious kitchen with a central island, a chandelier, and a sign indicating 'Quality' on the wall.
A hotel room with a flat-screen TV, a desk with a chair, a microwave, and a refrigerator.

15. Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
6.9 km from Santee National Wildlife Refuge
United States
Mark
Rp1.087.347
Rp1.306.033 total
includes taxes & fees
27 Sept - 28 Sept
Quality Inn & Suites Santee I-95
A gym with treadmills, an elliptical, dumbbells, and a bench.
A pool table area with multiple tables and chairs, a bar area with a counter and shelves, and a patterned carpet.
A hotel room with two beds, a desk, and a chair.

16. Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95
7.1 km from Santee National Wildlife Refuge
United States
Stevenson
Rp1.484.372
Rp1.647.653 total
includes taxes & fees
27 Sept - 28 Sept
Ramada by Wyndham Santee I-95
View all properties

Compare popular hotels close to Santee National Wildlife Refuge

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A tent with a view of a lake and boats, a wooden chair, and a potted plant.
Bells Marina & Resort
8.6
Excellent
101 reviews
View
A hotel room with a bed, a black armchair, a round mirror with lights, a black vanity with a sink, and a white towel on the wall.
Starlight Stays
7.4
Good
29 reviews
View
A hotel dining area with multiple tables and chairs, a large flat-screen TV, and a patterned wall design.
Hampton Inn Santee-I-95
9.6
Exceptional
1,000 reviews
View
A patio area with wicker furniture, a stone fire pit, and outdoor seating.
Fairfield Inn & Suites by Marriott Santee
9.8
Exceptional
1,001 reviews
View
A breakfast area with a self-service counter, refrigerated display, and a digital menu board.
Tru By Hilton Santee
9.2
Wonderful
962 reviews
View

Top Santee National Wildlife Refuge Hotel Reviews

Best Western Plus Santee Inn

Best Western Plus Santee Inn

10/10 Excellent
"Nice location and very convenient parking, Breakfast was very good."
Johnny 1-night trip
Posted 7 hours ago
Best Western Plus Santee Inn
Baymont by Wyndham Santee

Baymont by Wyndham Santee

8/10 Good
"Desk staff was courteous. There was a lot of renovations going on."
Carolyn 1-night trip
Posted 15 hours ago
Baymont by Wyndham Santee
Hampton Inn Manning

Hampton Inn Manning

8/10 Good
"My stay went well. Staff was great."
Sarah 2-night trip
Posted 2 days ago
Hampton Inn Manning
Tru By Hilton Santee

Tru By Hilton Santee

10/10 Excellent
"The elevator was full of fingerprints. Old ones"
Dorothy 1-night trip
Posted 2 days ago
Tru By Hilton Santee
SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning

8/10 Good
"I have stayed here several times and have always thought it was great. It’s starting to slip. Last time I was there I got up early to leave and there were cars double parked making it very hard to get out. This time check in felt like I was a bother. A car was parked in the spot obviously for the room right i n front of the spot. The group next door was very loud and slamming doors. The rooms are starting to need little things like painting and patching. The entry doors need work. I hope to stay again but will definitely think twice now."
John 1-night trip
Posted 3 days ago
SureStay Hotel by Best Western Manning
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

10/10 Excellent
"Nice breakfast. Easybparking. Very clean room and wonderful staff"
kathleen 1-night trip
Posted 3 days ago
Hampton Inn Santee-I-95
Bells Marina & Resort

Bells Marina & Resort

10/10 Excellent
"Love it"
Mark 1-night trip
Posted 5 days ago
Bells Marina & Resort
Baymont by Wyndham Manning

Baymont by Wyndham Manning

8/10 Good
"The staff was friendly and helpful!"
Katrina 2-night trip
Posted 5 days ago
Baymont by Wyndham Manning
Holiday Inn Santee by IHG

Holiday Inn Santee by IHG

10/10 Excellent
"Room was very clean and large. Staff were very friendly and enjoyed the breakfast."
Rita 1-night trip
Posted 9 days ago
Holiday Inn Santee by IHG

Other attractions near Santee National Wildlife Refuge

Pine Island

Commune with nature and explore the great outdoors at Pine Island during your travels in Summerton. While you're in the area, wander around the parks.
See properties

Santee Indian Mound and Fort Watson Site

You can learn about the history of Summerton with a visit to Santee Indian Mound and Fort Watson Site. While you're in the area, wander around the parks.
See properties

Santee State Park

8.0/10 (219 reviews)
You can take time to visit Santee State Park during your travels to Santee. While you're here, you can savour the top-notch restaurants.
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Santee Cooper Country Club

7.8/10 (94 reviews)
Enjoy a round of golf in Santee at Santee Cooper Country Club. While you're here, you can savour the top-notch restaurants.
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Santee National Golf Club

8.0/10 (74 reviews)
Enjoy a round of golf in Santee at Santee National Golf Club. While you're here, you can savour the top-notch restaurants.
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Santee Town Hall

Santee Town Hall is just one of the places to see in Santee, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savour the top-notch restaurants.
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Taw Caw Creek

6.6/10 (4 reviews)
Commune with nature and explore the great outdoors at Taw Caw Creek during your travels in Summerton. While you're in the area, wander around the parks.
See properties

Taw Caw Creek Park

6.4/10 (6 reviews)
Explore the great outdoors at Taw Caw Creek Park, a lovely green space in Summerton. While you're in the area, wander around the parks.
See properties

Frequently asked questions

What's the area like around Santee National Wildlife Refuge?
Santee National Wildlife Refuge is located in a welcoming area of Summerton known for its array of dining options and golfing. You'll find 160 hotels and other accommodations within a few miles for a convenient home base.
What's the best hotel to stay near Santee National Wildlife Refuge?
Tru By Hilton Santee is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. It's located 4.5 mi (7.2 km) from Santee National Wildlife Refuge. Other good choices within a few miles include Baymont by Wyndham Santee and Fairfield Inn & Suites by Marriott Santee.
How many hotels should I expect to find near Santee National Wildlife Refuge?
Expedia has 160 hotels and other accommodation options a few miles from Santee National Wildlife Refuge.
If I need to cancel the hotel reservation for my stay near Santee National Wildlife Refuge, will I receive a refund?
Yes! The majority of hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and get a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to get the best options available near Santee National Wildlife Refuge.