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Check prices for these dates

Next weekend
20 Nov - 22 Nov
In two weeks
27 Nov - 29 Nov

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Our top choices for Sioux Empire Medical Museum hotels

A spacious living room with a fireplace, large windows, and modern furniture.

1. Highpoint Hotel

Highpoint Hotel
3.0 star property
University Heights, 0.2 km from Sioux Empire Medical Museum
9.8 out of 10, Exceptional, (421 reviews)
"Great place to stay."
United States
Lee
The price is Rp2.212.029
Rp2.463.008 total
includes taxes & fees
10 Dec - 11 Dec
Highpoint Hotel
A stone pillar with a fire pit in the center, surrounded by blue chairs.

2. Clubhouse Hotel Suites Sioux Falls

Clubhouse Hotel Suites Sioux Falls
3.0 star property
Mall District, 2.8 km from Sioux Empire Medical Museum
9.6 out of 10, Exceptional, (1,269 reviews)
"Absolutely love staying here.. alway pleasant experience.. we've stayed here at least 10 times"
United States
Nicholas
The price is Rp2.769.133
Rp3.317.133 total
includes taxes & fees
13 Dec - 14 Dec
Clubhouse Hotel Suites Sioux Falls
A patio with wicker chairs and a round table with a fire pit.

3. Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
3.0 star property
University Heights, 0.2 km from Sioux Empire Medical Museum
9.4 out of 10, Exceptional, (683 reviews)
"The property was very clean and the staff was great."
United States
Ross
The price is Rp1.934.934
Rp2.159.035 total
includes taxes & fees
23 Nov - 24 Nov
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
A lobby with a large safe, a checkered floor, and a sofa with cushions.

4. Hotel On Phillips

Hotel On Phillips
2.5 star property
Downtown Sioux Falls, 1.9 km from Sioux Empire Medical Museum
9.6 out of 10, Exceptional, (1,644 reviews)
"Staff was friendly and the property was clean"
United States
Victoria
The price is Rp2.999.803
Rp3.327.329 total
includes taxes & fees
24 Nov - 25 Nov
Hotel On Phillips
A Hampton Inn hotel with a modern design, featuring a prominent red sign, a covered entrance, and stone pillars.

5. Hampton Inn Sioux Falls

Hampton Inn Sioux Falls
2.5 star property
Mall District, 3.1 km from Sioux Empire Medical Museum
9.2 out of 10, Wonderful, (1,001 reviews)
"Very friendly staff, good choices at breakfast and comfortable room."
United States
Mary
The price is Rp1.955.689
Rp2.181.802 total
includes taxes & fees
23 Nov - 24 Nov
Hampton Inn Sioux Falls
A modern building with a sign reading "THE STEEL DISTRICT" and a covered walkway.

6. Canopy By Hilton Sioux Falls Downtown

Canopy By Hilton Sioux Falls Downtown
4.0 star property
Downtown Sioux Falls, 2.5 km from Sioux Empire Medical Museum
9.4 out of 10, Exceptional, (294 reviews)
"Great stay super cute location"
United States
Marnie
The price is Rp2.708.143
Rp3.116.480 total
includes taxes & fees
23 Nov - 24 Nov
Canopy By Hilton Sioux Falls Downtown
A hotel reception area with a modern design, featuring a reception desk, computer, and a refrigerator stocked with beverages.

7. Holiday Inn Express & Suites Sioux Falls At Empire Mall by IHG

Holiday Inn Express & Suites Sioux Falls At Empire Mall by IHG
2.5 star property
Mall District, 3.1 km from Sioux Empire Medical Museum
8.8 out of 10, Excellent, (1,002 reviews)
"It's a good place"
United States
Hagel
The price is Rp1.765.982
Rp1.973.712 total
includes taxes & fees
6 Dec - 7 Dec
Holiday Inn Express & Suites Sioux Falls At Empire Mall by IHG
A long dining table with chairs, a bar area with bottles, and a brick wall with a chandelier.

8. Hilton Garden Inn Sioux Falls Downtown

Hilton Garden Inn Sioux Falls Downtown
3.0 star property
Downtown Sioux Falls, 2.1 km from Sioux Empire Medical Museum
8.8 out of 10, Excellent, (1,002 reviews)
"Great hotel amazing access to the main strip"
United States
Samuel
The price is Rp2.088.358
Rp2.436.577 total
includes taxes & fees
22 Nov - 23 Nov
Hilton Garden Inn Sioux Falls Downtown
A multi-level hotel lobby with a central atrium, multiple floors, and a variety of seating areas.

9. Sheraton Sioux Falls Hotel & Convention Center

Sheraton Sioux Falls Hotel & Convention Center
4.0 star property
Northwest Sioux Falls, 2.9 km from Sioux Empire Medical Museum
8.6 out of 10, Excellent, (1,001 reviews)
"Clean room friendly staff"
United States
Charmaine
The price is Rp1.918.912
Rp2.141.458 total
includes taxes & fees
22 Nov - 23 Nov
Sheraton Sioux Falls Hotel & Convention Center
A spacious lobby with multiple seating areas, a bar, and a staircase leading to an upper level.

10. Holiday Inn Sioux Falls-City Centre by IHG

Holiday Inn Sioux Falls-City Centre by IHG
3.0 star property
Downtown Sioux Falls, 1.9 km from Sioux Empire Medical Museum
8.6 out of 10, Excellent, (1,000 reviews)
"Very clean hotel with very helpful and friendly staff."
United States
Chad
The price is Rp2.075.484
Rp2.586.308 total
includes taxes & fees
23 Nov - 24 Nov
Holiday Inn Sioux Falls-City Centre by IHG
A modern living room with a grey sofa, two armchairs, a coffee table, and a flat-screen TV mounted on a wooden wall.

11. Country Inn & Suites by Radisson, Sioux Falls

Country Inn & Suites by Radisson, Sioux Falls
3.0 star property
Downtown Sioux Falls, 2 km from Sioux Empire Medical Museum
8.4 out of 10, Very good, (1,427 reviews)
"Great stay!"
United States
Hayley
The price is Rp1.550.714
Rp1.737.545 total
includes taxes & fees
22 Nov - 23 Nov
Country Inn & Suites by Radisson, Sioux Falls
A hotel room with two beds, a desk with a computer, a television, and a couch.

12. The Center Inn

The Center Inn
2.5 star property
All Saints, 2.4 km from Sioux Empire Medical Museum
8.4 out of 10, Very good, (941 reviews)
"Very nice, basic hotel with great location on the Avera hospital campus."
United States
thomas
The price is Rp1.911.029
Rp2.132.811 total
includes taxes & fees
15 Nov - 16 Nov
The Center Inn
A hotel room with a large bed, two bedside tables with lamps, a framed picture on the wall, and a carpeted floor.

13. Valley Inn

Valley Inn
2.5 star property
University Heights, 0.2 km from Sioux Empire Medical Museum
8.0 out of 10, Very good, (1,000 reviews)
"It was close to the airport and lots of places to eat. The rooms were spacious and comfortable."
United States
Doreen
The price is Rp1.786.009
Rp1.995.560 total
includes taxes & fees
15 Nov - 16 Nov
Valley Inn
An indoor swimming pool with a water slide and palm trees.

14. Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr
3.0 star property
Northwest Sioux Falls, 2.9 km from Sioux Empire Medical Museum
7.8 out of 10, Good, (1,661 reviews)
"Rooms were very clean. Staff was very helpful & nice. The bed was nice! Will stay again!"
United States
Julaine
The price is Rp1.129.682
Rp1.275.673 total
includes taxes & fees
23 Nov - 24 Nov
Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr
A reception area with a marble counter, a black office chair, and a potted plant.

15. Sioux Falls Inn

Sioux Falls Inn
2.0 star property
Northwest Sioux Falls, 3.1 km from Sioux Empire Medical Museum
5.8 out of 10, (10 reviews)
"A lot of remodeling going on throughout the place, so yes. A lot of debris and new furniture waiting ro be put in."
United States
Maria
The price is Rp945.984
Rp1.074.154 total
includes taxes & fees
15 Nov - 16 Nov
Sioux Falls Inn
A hotel room with a bathtub, a bed with a red and white bedspread, a small table, and a brown armchair.

16. Ramada by Wyndham Sioux Falls

Ramada by Wyndham Sioux Falls
2.0 star property
2.6 km from Sioux Empire Medical Museum
5.8 out of 10, (1,002 reviews)
"Great hotel!! Great customer service and my room was cleaned each day! Enjoy breakfast too!"
United States
Jonathan Robert
The price is Rp1.007.705
Rp1.141.931 total
includes taxes & fees
25 Nov - 26 Nov
Ramada by Wyndham Sioux Falls
An outdoor patio with a fire pit, seating, and a view of a building.

17. Staybridge Suites Sioux Falls Southwest by IHG

Staybridge Suites Sioux Falls Southwest by IHG
3.0 star property
South Sioux Falls, 5.2 km from Sioux Empire Medical Museum
9.6 out of 10, Exceptional, (558 reviews)
"Good clean rooms with comfortable beds and a good breakfast spread."
United States
Bailey
The price is Rp1.915.095
Rp2.137.337 total
includes taxes & fees
22 Nov - 23 Nov
Staybridge Suites Sioux Falls Southwest by IHG
A modern hotel lobby with seating areas, a bar, and a kitchen visible in the background.

18. Hampton Inn & Suites Southwest/Sioux Falls

Hampton Inn & Suites Southwest/Sioux Falls
2.5 star property
South Sioux Falls, 5.5 km from Sioux Empire Medical Museum
9.4 out of 10, Exceptional, (1,001 reviews)
"The bed was extremely comfortable, the room very clean and staff were very helpful!"
United States
Elizabeth
The price is Rp2.027.238
Rp2.260.292 total
includes taxes & fees
23 Nov - 24 Nov
Hampton Inn & Suites Southwest/Sioux Falls
An outdoor patio area with tables and chairs, string lights, and a view of the city skyline.

19. Comfort Inn & Suites at Sanford Sports Complex

Comfort Inn & Suites at Sanford Sports Complex
2.5 star property
Northwest Sioux Falls, 6 km from Sioux Empire Medical Museum
9.6 out of 10, Exceptional, (1,241 reviews)
"Great place, with friendly staff."
United States
Kristine
The price is Rp1.814.598
Rp2.027.092 total
includes taxes & fees
22 Nov - 23 Nov
Comfort Inn & Suites at Sanford Sports Complex
A deck with outdoor furniture, a fire pit, and a view of a body of water.

20. Hyatt Place Sioux Falls South

Hyatt Place Sioux Falls South
3.0 star property
Mall District, 3.8 km from Sioux Empire Medical Museum
9.4 out of 10, Exceptional, (1,022 reviews)
"Great place to stay! Friendly staff, very clean, excellent breakfast! Will stay here again!!"
United States
Jami
The price is Rp2.277.571
Rp2.534.909 total
includes taxes & fees
7 Dec - 8 Dec
Hyatt Place Sioux Falls South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Sioux Empire Medical Museum

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A spacious living room with a fireplace, large windows, and modern furniture.
Highpoint Hotel
3.0 star property
9.8
Exceptional
421 reviews
View
A stone pillar with a fire pit in the center, surrounded by blue chairs.
Clubhouse Hotel Suites Sioux Falls
3.0 star property
9.6
Exceptional
1,269 reviews
View
A patio with wicker chairs and a round table with a fire pit.
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
3.0 star property
9.4
Exceptional
683 reviews
View
A lobby with a large safe, a checkered floor, and a sofa with cushions.
Hotel On Phillips
2.5 star property
9.6
Exceptional
1,644 reviews
View
A Hampton Inn hotel with a modern design, featuring a prominent red sign, a covered entrance, and stone pillars.
Hampton Inn Sioux Falls
2.5 star property
9.2
Wonderful
1,001 reviews
View

Top Sioux Empire Medical Museum Hotel Reviews

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

10/10 Excellent
"Friendly staff Great Breakfast"
Dalene 1-night trip
Posted 3 hours ago
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

Other attractions near Sioux Empire Medical Museum

University of Sioux Falls

8.0/10 (242 reviews)
Explore the campus of University of Sioux Falls during your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls.
See properties

Frequently asked questions

What's the area like around Sioux Empire Medical Museum?
Sioux Empire Medical Museum is located in a welcoming area of Sioux Falls known for its beautiful waterfalls and sporting events. If you're looking for a convenient place to stay, take a look at the 136 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Sioux Empire Medical Museum?
Adjacent to Sioux Empire Medical Museum, Highpoint Hotel is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and free parking. Other good choices close by include Valley Inn and Home2 Suites By Hilton Sioux Falls/Sanford Medical Center.
How many hotels are there close to Sioux Empire Medical Museum?
Expedia has 136 hotels and other accommodation options within a mile from Sioux Empire Medical Museum.
If I need to cancel the hotel reservation for my stay near Sioux Empire Medical Museum, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then use the "fully refundable" filter to view the best options available near Sioux Empire Medical Museum.
What can I see and do near Sioux Empire Medical Museum?
Washington Pavilion of Arts and Science, Old Courthouse Museum and Center for Western Studies feature a variety of fascinating exhibits to see while you're in town. Learn about local history at St. Joseph Cathedral and Pettigrew Home and Museum. You can enjoy live performances at Edith Mortenson Theatre Center and Orpheum Theatre Center.