The Best Hotels Closest to University of Chicago Medicine in Chicago - 2026 Updated Prices

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Our top choices for University of Chicago Medicine hotels

A modern hotel room with large windows, a sofa, chairs, a dining table, and a coffee table.

An outdoor seating area with sofas, chairs, and tables, surrounded by trees and string lights.

A bar area with a marble countertop, multiple shelves of bottles, and a large TV screen. There are several bar stools and a round table with a vase of flowers.

A spacious living area with a modern chandelier, comfortable seating, and a fireplace.

1. Sophy Hyde Park

Hyde Park, 1.6 km from University of Chicago Medicine

Elaine

Rp4.768.990

Rp6.118.458 total

includes taxes & fees

9 Sept - 10 Sept

A room with large windows, a wooden floor, and a built-in air conditioning unit.

A hotel room with a large bed, a wooden headboard, a patterned bedspread, and a view through an open door to another room.

2. Best Motel By OYO Chicago I-90

1.7 km from University of Chicago Medicine

Saul

Rp1.457.634

Rp1.711.116 total

includes taxes & fees

15 Sept - 16 Sept

A bedroom with a bed, a sofa, a desk, a TV, and a window.

A small dining area with a table and two chairs, a potted plant on the table, and a view of a parking lot through a window.

A room with a white console table, a decorative painting, and a vase with flowers. There is a kitchen area visible through an open doorway.

A Gateway Inn sign with a bear statue and a welcome back sign.

3. GATEWAY INN

13.4 km from University of Chicago Medicine

Noemi

Rp1.384.032

Rp1.591.282 total

includes taxes & fees

1 Oct - 2 Oct

A modern hotel lobby with a seating area, a bar, and a kitchen.

A DoubleTree by Hilton hotel with a modern design, a covered entrance, and well-maintained landscaping.

A modern living room with a fireplace, a flat-screen TV, a pool table, and a chess table.

A modern hotel room with a sofa, a flat-screen TV, a fireplace, and a dining area.

4. DoubleTree by Hilton Chicago Midway Airport

11.8 km from University of Chicago Medicine

Jessica

Rp3.235.796

Rp3.801.475 total

includes taxes & fees

7 Sept - 8 Sept

A modern reception area with a wooden reception desk, a seating area with sofas and a coffee table, and a large wall-mounted artwork.

A modern lobby with a sofa set, a coffee table, and a large abstract wall art piece.

A hotel room with two beds, a sofa, a desk, and a chair.

5. Hyatt Place Chicago Midway Airport

11.5 km from University of Chicago Medicine

Tracy

Rp3.495.568

Rp4.106.594 total

includes taxes & fees

28 Sept - 29 Sept

A modern hotel lobby with a reception desk, seating area, and large windows offering city views.

A swimming pool with a ceiling of lights, large windows, and potted plants.

A modern hotel room with a large window offering a city view, three armchairs arranged around a central coffee table, and a decorative hanging plant.

A modern dining area with round tables, comfortable chairs, and a dessert display.

6. The Langham, Chicago

River North, 11.2 km from University of Chicago Medicine

Michael

Rp11.090.000

Rp13.185.212 total

includes taxes & fees

7 Sept - 8 Sept

A high-rise hotel with multiple floors, large windows, and a prominent Tiffany & Co. store on the ground level.

A rooftop bar with seating and a view of the city skyline at night.

A modern indoor pool area with large windows, potted palm plants, and lounge chairs.

A modern bar area with a checkered floor, bar stools, and a bartender.

7. The Peninsula Chicago

Streeterville, 12 km from University of Chicago Medicine

Rp11.090.000

Rp13.184.904 total

includes taxes & fees

7 Sept - 8 Sept

A modern indoor pool area with lounge chairs, a wooden table, and large windows.

A modern hotel lobby with a reception desk, seating area, and artwork on the walls.

A modern hotel with multiple floors, a covered entrance, and a parking lot.

A modern hotel room with a large bed, a desk, a chair, a TV, and a sliding door leading to a shower area.

8. Hampton Inn & Suites Chicago Medical District UIC

11.2 km from University of Chicago Medicine

Alisa

Rp2.850.574

Rp3.389.050 total

includes taxes & fees

7 Sept - 8 Sept

An outdoor seating area with tables and chairs, a planter with greenery, and a large brick structure in the background.

A waterfront cityscape with modern buildings, a Ferris wheel, and several cruise ships docked.

A spacious outdoor dining area with large windows overlooking the sea, featuring multiple tables and stools.

A modern living room with a large window overlooking a body of water, a tripod, and a sofa.

9. Sable at Navy Pier Chicago, Curio Collection by Hilton

Streeterville, 11.4 km from University of Chicago Medicine

Ashraf

Rp3.242.716

Rp4.467.079 total

includes taxes & fees

8 Sept - 9 Sept

The Riu Plaza Chicago Hotel facade with a grand entrance, large windows, and a modern architectural design.

A modern hotel lobby with a central seating area, a reception desk, and a decorative wall with a unique design.

A couple dining at a table with a city view, surrounded by chairs and a variety of dishes.

A spacious lobby with a marble floor, a reception desk, and a glass partition.

10. Hotel Riu Plaza Chicago

Streeterville, 11.7 km from University of Chicago Medicine

Donna

Rp2.732.253

Rp3.754.079 total

includes taxes & fees

7 Sept - 8 Sept

A modern building with a colorful facade and a red circular seating area.

A modern high-rise building with a glass facade, surrounded by other tall buildings.

A modern hotel room with a large window offering a city view, a contemporary light fixture, and a clean, minimalist design.

A modern interior with wooden shelves, colorful chairs, and hanging plants.

11. citizenM Chicago Downtown

Theatre District, 11 km from University of Chicago Medicine

lakadria

Rp3.012.740

Rp3.581.847 total

includes taxes & fees

7 Sept - 8 Sept

A modern hotel room with a large bed, a bedside table, a nightstand, and a wall-mounted light fixture.

A room with a window, a white shelf, a colorful striped rug, and a large number '6' on the wall.

A bathroom with a marble wall, a bathtub, a toilet, and a shower curtain.

12. Motel 6 - Chicago, IL

9.2 km from University of Chicago Medicine

Asia

Rp1.594.803

Rp1.872.152 total

includes taxes & fees

15 Sept - 16 Sept

A hallway with wooden flooring, a dining area with a table and chairs, and a blue sofa.

A room with a wooden herringbone ceiling, a wall clock, and shelves with various decorative items and books.

A dining area with a wooden table and chairs, a rock sculpture centerpiece, and a large green wall art piece.

A modern kitchen with white cabinets, stainless steel appliances, and patterned wallpaper.

13. Villa Dubois Guest House

4.4 km from University of Chicago Medicine

Robert

Rp2.166.514

Rp2.543.273 total

includes taxes & fees

9 Sept - 10 Sept

A cityscape with a river, a bridge, and a dining area with tables and chairs.

A high-rise hotel with a prominent 'TRUMP' sign, reflecting in the water, surrounded by other tall buildings.

A modern hotel room with large floor-to-ceiling windows offering a city view.

A modern hotel room with large windows, white furniture, and a view of tall buildings.

14. Trump International Hotel & Tower Chicago

River North, 11.3 km from University of Chicago Medicine

Jorge

Rp8.971.763

Rp10.666.517 total

includes taxes & fees

20 Sept - 21 Sept

A spacious lobby with a plush teal sofa, a round coffee table, and a large chandelier.

A hotel entrance with a sign reading "The Lasalle Hotel" and a "Grill on 21" sign.

A modern lobby with a bar area, plush seating, and a chandelier.

A grand staircase with a geometric patterned floor, marble walls, and a chandelier.

15. The LaSalle Chicago, Autograph Collection by Marriott

Theatre District, 10.3 km from University of Chicago Medicine

Anthony

Rp6.370.096

Rp7.573.407 total

includes taxes & fees

6 Sept - 7 Sept

A restaurant with tables and chairs arranged in a corridor, large windows, and hanging lamps.

A rooftop pool area with city views, two lounge chairs, and a small table with a vase.

A modern hotel entrance with a prominent "STREGIS" sign, large glass windows, and a well-lit facade.

A modern hotel lobby with a large seating area, a view of the city, and a green accent wall.

16. The St. Regis Chicago

11 km from University of Chicago Medicine

Princess

Rp11.427.136

Rp13.585.725 total

includes taxes & fees

21 Sept - 22 Sept

A grand hotel facade with classical architecture, featuring tall columns, ornate detailing, and a prominent entrance with a marquee.

A spacious living area with a pool table, comfortable seating, a fireplace, and large windows.

A spacious lobby with a grand staircase, modern seating, and a large window providing natural light.

A modern hotel lobby with a long bar, seating area, and large windows.

17. Hyatt House Chicago Medical/University District

11 km from University of Chicago Medicine

Daniel

Rp3.655.264

Rp4.345.745 total

includes taxes & fees

8 Sept - 9 Sept

A spacious lobby with a wooden floor, a staircase with a green accent, and a reception area with a sign reading "Welcome".

A Sleep Inn hotel with a prominent tower, a covered entrance, and a landscaped front yard.

A hotel reception area with a staircase, reception desk, and a large potted plant.

A buffet setup with coffee machines, milk dispensers, and food containers.

18. Sleep Inn Midway Airport Bedford Park

11.5 km from University of Chicago Medicine

KAREN

Rp2.022.550

Rp2.376.092 total

includes taxes & fees

23 Sept - 24 Sept

A rooftop pool with lounge chairs and a city skyline in the background.

A bartender preparing a cocktail with various ingredients and bottles of liquor on the bar counter.

A modern dining area with a round table and chairs, large windows with a city view, and a decorative light fixture.

19. Viceroy Chicago

12.8 km from University of Chicago Medicine

Cristian

Rp5.575.498

Rp7.216.216 total

includes taxes & fees

7 Sept - 8 Sept

A corridor with ornate black metal railings and a patterned carpet.

A modern hotel room with a sofa, a small table, a bench, a TV, and a cabinet.

A dining area with tables and chairs, a hanging light fixture, and a view of the street through a window.

A bed with a pillow featuring a pineapple design and the text "Sleep with me." A window reveals a cityscape at night.

20. Staypineapple, An Iconic Hotel, The Loop

Theatre District, 10.7 km from University of Chicago Medicine

marcus

Rp2.743.188

Rp3.787.014 total

includes taxes & fees

7 Sept - 8 Sept

View all properties

Compare popular hotels close to University of Chicago Medicine

Property	Property class	Guest rating
Sophy Hyde Park	9.4 Exceptional 1,000 reviews	View
Best Motel By OYO Chicago I-90	3.6 129 reviews	View
GATEWAY INN	8.4 Very good 177 reviews	View
DoubleTree by Hilton Chicago Midway Airport	9.2 Wonderful 999 reviews	View
Hyatt Place Chicago Midway Airport	9.0 Wonderful 1,308 reviews	View

Top University of Chicago Medicine Hotel Reviews

Congress Plaza Hotel

10/10 Excellent

"It was great! We arrived early and the front desk was able to check us in early and our room and view was just amazing! Loved how clean everything was."

Chicago Lake Shore Hotel

8/10 Good

"Room was kept clean, parking was right outside the room-great. Staff was helpful, professional and available"

Sophy Hyde Park

10/10 Excellent

"What an amazing boutique hotel that we randomly booked. It is now our new favorite place to stay. Having never stayed in Chicago, we will now return to stay here again. Everything was amazing from the decor and the comfort of the room, the ambience of the flames in the lobby, the amazing food, vinyl record player in the room but most of all the staff. Aisha, our waitress and Alayna and Tiara at the front desk were kind, very helpful and welcoming. 11 out of 10 stay."

Hampton Inn Chicago McCormick Place

10/10 Excellent

"We have stayed here twice for events we attended at Soldier field. This hotel is extremely conveniently located and walkable distance to and from Soldier field. Short walk to China town as well."

Hyatt Place Chicago-South/University Medical Center

10/10 Excellent

"This hotel is well kept. The staff is very nice and helpful. There is good food near by and at night it's quiet. I didnt realize that our window faced the front of the building until the last day. Thats how quiet it was. Parking, like every major city, SUCKS. PAY THE METER."

Hilton Garden Inn Chicago McCormick Place

10/10 Excellent

"Super clean and comfy rooms. The rooftop bar is a must!"

SpringHill Suites by Marriott Chicago Chinatown

10/10 Excellent

"The hotel was dope. Clean, safe, friendly staff and a modern room. I loved the fact that I could walk out the hotel and literally everything was right there restaurants, shops, stores. Came on sat so parking was a little tough. I would definitely stay again."

Villa Dubois Guest House

10/10 Excellent

"Great place to stay. Quiet, clean and tastefully furnished. Good location for Southside destinations and good access to public transportation."

Admiral Motel By Oyo Chicago I-94

10/10 Excellent

"Air conditioner was broken, toilet was leaking from the floor, but staff, guests and neighbours were very friendly. Overall good given the affordable cost. Not a five star hotel, but doesn’t pretend to be"

Frequently asked questions

What's the area like around University of Chicago Medicine?

University of Chicago Medicine is located in a vibrant area of Chicago known for its beautiful lakeside setting and stunning architecture. If you're looking for a convenient place to stay, take a look at the 73 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay near University of Chicago Medicine?

Sophy Hyde Park is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and a fitness centre. It's located 1 mi (1.6 km) from University of Chicago Medicine. Other good choices within 5 miles include Hyatt Place Chicago-South/University Medical Center and Best Motel By OYO Chicago I-90.

How many hotels are there close to University of Chicago Medicine?

Expedia has 73 hotels and other accommodation options within a mile from University of Chicago Medicine.

If I need to cancel the hotel reservation for my stay near University of Chicago Medicine, will I receive a refund?

Yes, most room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you might be able to cancel it and get a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to review the best options available near University of Chicago Medicine.

What can I see and do near University of Chicago Medicine?

You might want to spend some time browsing the exhibits at Griffin Museum of Science and Industry, Renaissance Society or DuSable Black History Museum and Education Center. Explore landmarks like Robie House, Barack Obama Residence and Ida B Wells House. You can watch performances at Arie Crown Theater, Ramova Theatre and Radius - Chicago if you're interested in local theatre.

How can I get to University of Chicago Medicine?

If you'd like to explore more of the area, jump aboard a train from Chicago 55th-56th-57th Street Station, Chicago 59th Street Station or Chicago 51st-53rd Street Station (Hyde Park). There might not be many public transport options to choose from close to University of Chicago Medicine so consider a car rental to maximise your time.

Search Hotels Near University of Chicago Medicine, Chicago

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Our top choices for University of Chicago Medicine hotels

1. Sophy Hyde Park

2. Best Motel By OYO Chicago I-90

3. GATEWAY INN

4. DoubleTree by Hilton Chicago Midway Airport

5. Hyatt Place Chicago Midway Airport

6. The Langham, Chicago

7. The Peninsula Chicago

8. Hampton Inn & Suites Chicago Medical District UIC

9. Sable at Navy Pier Chicago, Curio Collection by Hilton

10. Hotel Riu Plaza Chicago

11. citizenM Chicago Downtown

12. Motel 6 - Chicago, IL

13. Villa Dubois Guest House

14. Trump International Hotel & Tower Chicago

15. The LaSalle Chicago, Autograph Collection by Marriott

16. The St. Regis Chicago

17. Hyatt House Chicago Medical/University District

18. Sleep Inn Midway Airport Bedford Park

19. Viceroy Chicago

20. Staypineapple, An Iconic Hotel, The Loop

Compare popular hotels close to University of Chicago Medicine

Top University of Chicago Medicine Hotel Reviews

Congress Plaza Hotel

Chicago Lake Shore Hotel

Sophy Hyde Park

Hampton Inn Chicago McCormick Place

Hyatt Place Chicago-South/University Medical Center

Hilton Garden Inn Chicago McCormick Place

SpringHill Suites by Marriott Chicago Chinatown

Villa Dubois Guest House

Admiral Motel By Oyo Chicago I-94

Frequently asked questions