Upstate South Carolina Best Western Hotels: Upstate South Carolina Hotel Guide

A bench, a bicycle, and a lake surrounded by trees.

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Our top choices for Upstate South Carolina Best Western

A modern lobby with a reception desk, seating area, and a television screen.

A hotel room with two beds, a desk with a lamp, a chair, a patterned rug, and a large window.

A swimming pool with lounge chairs and tables, surrounded by brick buildings and a covered seating area.

A hotel with a covered entrance, brick exterior, and a sign indicating it is a Best Western hotel.

1. Best Western Spartanburg I-26

Spartanburg

Santhosh

Rp1.675.112

Rp1.859.374 total

includes taxes & fees

1 Nov - 2 Nov

A modern living room with a fireplace, two sofas, and a coffee table.

A reception area with two wooden reception desks, a blue accent wall, and a mounted television.

A hotel room with two beds, a desk, a TV, and a window with curtains.

A modern gym with various exercise equipment, motivational wall graphics, and a large window offering a view of the outdoors.

2. Best Western Spartanburg Northwest

Spartanburg

Herbert

Rp1.598.272

Rp1.809.564 total

includes taxes & fees

22 Nov - 23 Nov

A fire pit with a bench on a concrete patio, surrounded by trees and a view of a body of water.

A modern restaurant with wooden flooring, bar seating, and a coffee station.

A Best Western hotel with a modern design, multiple flags, and well-lit signage.

A hotel room with two beds, a desk, a chair, a desk lamp, a bathroom with a mirror, and a window with curtains.

3. Best Western Travelers Rest Greenville

Travelers Rest

Susan

Rp2.068.171

Rp2.274.989 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.

A reception area with a brick wall, a reception desk, and a glass door leading outside.

A multi-story hotel with a prominent entrance, parking area, and a car parked in front.

A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.

4. Best Western Seneca-Clemson

Seneca

Michelle

Rp1.690.661

Rp1.859.727 total

includes taxes & fees

27 Oct - 28 Oct

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Top Upstate South Carolina Hotel Reviews

Best Western Spartanburg I-26

10/10 Excellent

"5/5 Stars - A Fantastic Stay from Start to Finish! I had an absolutely wonderful time staying at this hotel, and I can't recommend it enough! From the moment we walked through the doors, the staff was incredibly warm, welcoming, and always ready to help with a smile. It really set a positive tone for the entire trip. The room itself was spotless and exceptionally comfortable. It is always a huge relief to check into a hotel and immediately see how much they prioritize cleanliness. On top of that, the amenities were absolutely awesome. Everything was well-maintained, modern, and exactly what we needed to relax and enjoy our downtime. One of the biggest highlights of the stay was the morning breakfast. It was both nice and genuinely delicious, offering a great variety of fresh, high-quality options to kick off the day perfectly. If you are looking for a clean, comfortable, and welcoming place to stay in Spartanburg, this is definitely the spot. I will absolutely be booking here again!"