"First and foremost, if you are staying at Mayo - you must know that this is not the correct hotel to stay at if you desire to quickly run back to the hotel between appointments. It is a 15 minute walk to the closest Mayo building, more with construction.
It is also important to know it is directly next to active train tracks, which will wake you up at 2:45AM at least once on your stay.
The person we checked in with was slightly unpleasant, mainly treating us like we were inconvenient for asking basic questions. Other workers were kind and generous.
The hotel appears new and the lobby is beautifully modern but the hallways upstairs were a bit dingy. Our room was base-level clean but needed deeper cleaning - mascara on the bathroom walls, stains on ceiling above shower, damaged blinds. Nothing to ruin a stay, but weird for a newer, not cheap hotel.
Overall, it was safe, it was clean enough, and we managed walking. But can pay similar and stay somewhere closer/nicer if a Mayo patient."