Photo by Alice Burghart

Cape Girardeau Hotel Guide - 3 Stars Hotels in Cape Girardeau, Missouri

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Our top choices for Cape Girardeau 3-star hotels

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1004)
"Great place and staff, very accommodating!"
United States
Megan
The price is Rp1.497.974
Rp1.689.735 total
includes taxes & fees
21 Dec - 22 Dec
Drury Plaza Hotel Cape Girardeau Conference Center

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
8.8 out of 10, Excellent, (668)
"Great place "
United States
GUY
The price is Rp1.400.761
Rp1.515.973 total
includes taxes & fees
7 Jan - 8 Jan 2026
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (468)
"The staff was very helpful and friendly. The rooms were modern and clean. The downtown location was perfect for us. "
United States
Deborah
The price is Rp1.930.936
Rp2.188.021 total
includes taxes & fees
24 Dec - 25 Dec
Courtyard by Marriott Cape Girardeau Downtown

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1003)
"Very friendly staff and great breakfast"
United States
Ray
The price is Rp1.497.974
Rp1.689.735 total
includes taxes & fees
19 Dec - 20 Dec
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1004)
"Breakfast was great- staff was welcoming. Will stay there again."
United States
Laura
The price is Rp1.381.452
Rp1.460.520 total
includes taxes & fees
16 Dec - 17 Dec
Drury Inn & Suites Jackson MO

EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.6 out of 10, Exceptional, (83)
"Cute room, great food, fun soda fountain and friendly owners! Will return! "
United States
Leslie
EC Reed's Mercantile and Hotel

Makanda Inn

Makanda Inn
3.5 star property
Makanda
10.0 out of 10, Exceptional, (33)
"I had a great stay - wonderful hosts and yummy breakfast."
United States
Julie
Makanda Inn

Cozy Anna Home Near Southern Illinois Attractions!

Cozy Anna Home Near Southern Illinois Attractions!
3.0 star property
Anna
10.0 out of 10, Exceptional, (1)
"Good communication with the owners. Nice perks such as coffee, tea, and hygiene items."
United States
Harvey
Cozy Anna Home Near Southern Illinois Attractions!

Oak Grove Cabins

Oak Grove Cabins
3.0 star property
Makanda
10.0 out of 10, Exceptional, (5)
"We stayed in a cabin in the woods. It was very nice and well furnished. Bed was a little hard but not bad. Very clean and well kept. Very private location so it was very peaceful."
United States
Joy
Oak Grove Cabins
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Explore similar 4-star hotels

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Cape Girardeau

Explore the mighty Mississippi from the riverfront park where historic murals tell stories of river life. Climb to the top of Academic Hall at Southeast Missouri State or hunt for antiques along downtown's brick-paved streets.

Beautiful city by the Mississippi River
Photo by Alice Burghart
Open Photo by Alice Burghart

Top Cape Girardeau Hotel Reviews

Frequently asked questions

What are the best 3-star hotels in Cape Girardeau?
Travellers speak highly of Courtyard by Marriott Cape Girardeau Downtown. It features a cafe and premium bedding, and is around 0.64 kilometres west of central Cape Girardeau. Drury Plaza Hotel Cape Girardeau Conference Centre is another leading 3-star hotel. Located roughly 8 kilometres west of the downtown area, it offers a swimming pool and front desk services.
How much does it cost to stay in a 3-star hotel in Cape Girardeau?
Take advantage of Expedia's filters to look for an inexpensive 3-star hotel for your upcoming Cape Girardeau break. Simply set your ideal budget with our easy-to-use pricing tool. You can also choose the amenities you'd like, preferred neighbourhood and plenty more.

  • Search for the lowest price per night right now from Rp1.808.255

What is the difference between a 4-star and 3-star hotel in Cape Girardeau?
Book a 3-star hotel and you can expect comfortable and well-kept rooms and conveniences such as free WiFi, fitness equipment and tea and coffee making facilities. These properties may also feature a bar and restaurant. Upgrade your Cape Girardeau trip by picking a 4-star hotel. With things like a day spa, 24-hour room service and deluxe toiletries, you'll experience an enhanced level of relaxation and comfort.