A coastal town with terracotta-roofed houses, a beach, and a castle on a hill.

Mytilene Hotel Guide - 5 Stars Hotels in Mytilene, Lesvos

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Mytilene 5 Star Hotels

Tonight
5 Oct - 6 Oct
Tomorrow
6 Oct - 7 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Our top choices for Mytilene 5-star hotels

A resort with a pool, outdoor seating, and a view of the sea at dusk.
A spacious living room with a large window, a sofa, a coffee table, and a dining area with chairs and a table.
A modern hotel room with a large bed, a desk, and a view of the ocean.
A modern hotel room with a large bed, a dining area with a view of the sea, and a balcony with a table and chairs.

1. Mythical Coast Wellness Retreat

Mythical Coast Wellness Retreat
Lesvos
United States
Jack
Rp1.466.817
Rp1.908.715 total
includes taxes & fees
31 Oct - 1 Nov
Mythical Coast Wellness Retreat
A person standing on a balcony overlooking a pool and a modern building with a clear view of the sea.
A modern hotel with a swimming pool, outdoor seating, and a view of the sea.
A modern bar area with seating and a bar counter.
A hotel room with a bed, a desk, a TV, and a window with a view of buildings.

2. Elysion Hotel

Elysion Hotel
Lesvos
Turkey
ANINDYA
Rp2.071.525
Rp3.074.294 total
includes taxes & fees
25 Oct - 26 Oct
Elysion Hotel
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mytilene.
Loriet Hotel

Loriet Hotel

Vareia, Mitilene Lesvos Lesvos Island
Rp1.363.325
Rp1.553.832 total
1 Nov - 2 Nov
includes taxes & fees
8.4/10 Very good! (92 reviews)
Loriet Hotel
Heliotrope Hotels

Heliotrope Hotels

Varia Lesvos Lesvos Island
Rp1.537.771
Rp1.885.811 total
6 Oct - 7 Oct
includes taxes & fees
Heliotrope Hotels
Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel

7, Skra str, Hatzidimitriou Park Lesvos
Rp2.246.303
Rp2.661.974 total
6 Oct - 7 Oct
includes taxes & fees
9.6/10 Exceptional! (172 reviews)
Theofilos Paradise Boutique Hotel
Still don't see what you're looking for?
See all properties in Mytilene.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Mytilene

The harbour city's neoclassical mansions and Byzantine castle offer glimpses into its rich past as a trading centre. Explore the Archaeological Museum's ancient artefacts, then enjoy fresh seafood at tavernas along the waterfront promenade.

See all hotels in Mytilene
A coastal town with terracotta-roofed houses, a beach, and a castle on a hill.

Top Mytilene Hotel Reviews

Mythical Coast Wellness Retreat

Mythical Coast Wellness Retreat

8/10 Good
"Breakfast was below normal standards for such a property. Nescafé isn’t a coffee you offer at a hotel charging 100+ USD / night. Turkish tea is terrible. Except breakfast and dining overall good hotel to stay."
MUSTAFA 1-night trip
Posted 2 days ago
Mythical Coast Wellness Retreat

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Mytilene?
How much you pay for a 5-star hotel in Mytilene depends on factors such as when you plan to travel and the length of your trip. A top tip for scoring the best deal? Use our pricing filters to check out the available options for your preferred dates.
  • Search for the lowest price per night from Rp1.553.832
What makes a hotel 5 stars in Mytilene?
From fine dining venues and 24-hour fitness centres to pools and dreamy bedding, the 5-star experience in Mytilene is all about luxury and comfort. But it takes more than just top-notch perks to earn a 5-star rating. Accommodation must also deliver superb guest services like in-room massage treatments, dry cleaning and laundry and a nightly turn-down service.
Are there any 5-star all-inclusive resorts in Mytilene?
Find an indulgent getaway that includes your lodging, food, activities and entertainment in Mytilene with our filter tool. Search for properties rated 5 stars and select the "All inclusive" filter. Be sure to check what's included in the price. That way, you can take full advantage of all the perks on offer when you arrive.