Find hotels in Defiance, MO from Rp1.216.204

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
15 May - 17 May
Next weekend
22 May - 24 May

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Defiance hotels

Standard Room, 2 Queen Beds | In-room safe, desk, laptop workspace, blackout curtains

Super 8 by Wyndham Warrenton

Super 8 by Wyndham Warrenton
2.0 star property
Warrenton
7.4 out of 10, Good, (647 reviews)
"The parking was easy, the room was verry clean."
United States
Gary
The price is Rp1.162.348
Rp1.327.693 total
includes taxes & fees
3 Jun - 4 Jun
Super 8 by Wyndham Warrenton
Reception

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
Fenton
8.0 out of 10, Very good, (1,273 reviews)
"Breakfast was great and the pool was very comfortable. "
United States
Nicholas
The price is Rp1.564.463
Rp1.806.768 total
includes taxes & fees
18 May - 19 May
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Indoor pool

Baymont by Wyndham Warrenton

Baymont by Wyndham Warrenton
2.5 star property
Warrenton
7.6 out of 10, Good, (1,001 reviews)
"Excellent place to stay!"
United States
Steven
The price is Rp1.296.445
Rp1.480.863 total
includes taxes & fees
10 Jun - 11 Jun
Baymont by Wyndham Warrenton
Lobby

Quality Inn Foristell

Quality Inn Foristell
2.5 star property
Foristell
8.2 out of 10, Very good, (985 reviews)
"Good value for the price - clean, comfortable room, decent breakfast offerings. lots of roadwork in the area currently."
United States
John
The price is Rp1.534.664
Rp1.733.403 total
includes taxes & fees
8 Jun - 9 Jun
Quality Inn Foristell
Premium bedding, desk, iron/ironing board, free WiFi

Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
O'Fallon
9.0 out of 10, Wonderful, (1,004 reviews)
"Everything was excellent, location amenities, food.."
United States
FERNANDO
The price is Rp1.423.705
Rp1.679.103 total
includes taxes & fees
20 May - 21 May
Sleep Inn & Suites O'Fallon MO - Technology Drive
Exterior

WoodSpring Suites St Peters-OFallon

WoodSpring Suites St Peters-OFallon
2.5 star property
St. Peters
8.6 out of 10, Excellent, (111 reviews)
"It was very clean, spacious and quiet. I like that it was non smoking and the staff was friendly"
United States
Kimbra
The price is Rp1.359.004
Rp1.609.041 total
includes taxes & fees
11 Jun - 12 Jun
WoodSpring Suites St Peters-OFallon
Exterior

Best Western Plus Washington Hotel

Best Western Plus Washington Hotel
2.5 star property
Washington
9.2 out of 10, Wonderful, (683 reviews)
"Very clean and staff were friendly. Breakfast was good and will definitely stay here again. "
United States
Rod
The price is Rp2.261.241
Rp2.574.423 total
includes taxes & fees
17 May - 18 May
Best Western Plus Washington Hotel
Room, 2 Queen Beds, Non Smoking | Desk, blackout curtains, iron/ironing board, free cots/infant beds

Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66
3.0 star property
Fenton
7.8 out of 10, Good, (1,213 reviews)
"Clean and a safe place to stay"
United States
Cindy
The price is Rp1.489.965
Rp1.720.730 total
includes taxes & fees
17 May - 18 May
Wingate by Wyndham St. Louis/Fenton Route 66
Lobby

Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
3.0 star property
St. Peters
9.4 out of 10, Exceptional, (1,001 reviews)
"Great location and clean hotel!"
United States
Admir
The price is Rp2.085.776
Rp2.397.600 total
includes taxes & fees
26 May - 27 May
Drury Inn & Suites St. Louis St. Peters
Exterior

Holiday Inn Express St. Louis West - O'Fallon by IHG

Holiday Inn Express St. Louis West - O'Fallon by IHG
2.5 star property
O'Fallon
8.6 out of 10, Excellent, (925 reviews)
"Clean friendly staff"
United States
Kayla
The price is Rp1.928.190
Rp2.274.388 total
includes taxes & fees
26 May - 27 May
Holiday Inn Express St. Louis West - O'Fallon by IHG
Room, 2 Queen Beds, Non Smoking | In-room safe, desk, blackout curtains, iron/ironing board

Super 8 by Wyndham Washington

Super 8 by Wyndham Washington
2.0 star property
Washington
8.4 out of 10, Very good, (724 reviews)
" Great staff at the desk. The best. "
United States
Mary
The price is Rp1.514.506
Rp1.724.265 total
includes taxes & fees
1 Jun - 2 Jun
Super 8 by Wyndham Washington
In-room safe, desk, laptop workspace, blackout curtains

Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
St. Charles
8.4 out of 10, Very good, (1,002 reviews)
"Room was clean breakfast was wonderful. "
United States
Eileen
The price is Rp1.815.128
Rp2.086.126 total
includes taxes & fees
31 May - 1 Jun
Comfort Suites St Charles - St Louis
Indoor pool

Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters
2.5 star property
St. Charles
8.0 out of 10, Very good, (1,003 reviews)
"Friendly staff. Comfy bed. Good breakfast. "
United States
Melanie
The price is Rp1.991.914
Rp2.289.247 total
includes taxes & fees
28 May - 29 May
Hampton Inn St. Charles St. Peters
Free daily buffet breakfast

Best Western Plus Fenton

Best Western Plus Fenton
2.5 star property
Fenton
9.2 out of 10, Wonderful, (289 reviews)
"Staff and breakfast were amazing!"
United States
Shilo
The price is Rp1.733.270
Rp2.001.720 total
includes taxes & fees
26 May - 27 May
Best Western Plus Fenton
Lobby

Days Inn by Wyndham St Peters/St Charles

Days Inn by Wyndham St Peters/St Charles
2.0 star property
St. Peters
6.2 out of 10, (1,001 reviews)
"Parking was good"
United States
raul
The price is Rp1.262.641
Rp1.451.406 total
includes taxes & fees
21 May - 22 May
Days Inn by Wyndham St Peters/St Charles
Lobby

Quality Inn Near Six Flags St. Louis

Quality Inn Near Six Flags St. Louis
2.5 star property
Pacific
8.4 out of 10, Very good, (377 reviews)
"Nice place! Will Use again"
United States
Jonathan
The price is Rp1.809.640
Rp2.071.605 total
includes taxes & fees
20 May - 21 May
Quality Inn Near Six Flags St. Louis
Reception

Hampton Inn St. Louis Wentzville

Hampton Inn St. Louis Wentzville
2.5 star property
Wentzville
9.0 out of 10, Wonderful, (703 reviews)
"Good location, clean and friendly staff. "
United States
Michelle
The price is Rp2.369.921
Rp2.712.376 total
includes taxes & fees
31 May - 1 Jun
Hampton Inn St. Louis Wentzville
Cleanliness standards

Relax Inn Saint Charles

Relax Inn Saint Charles
2.0 star property
St. Charles
6.8 out of 10, (1,001 reviews)
"Cleanses and staff was great!"
United States
Tamerra
The price is Rp1.100.988
Rp1.265.262 total
includes taxes & fees
19 May - 20 May
Relax Inn Saint Charles
Lobby

Drury Inn & Suites Southwest St. Louis

Drury Inn & Suites Southwest St. Louis
3.0 star property
Valley Park
9.6 out of 10, Exceptional, (1,017 reviews)
"Amazing breakfast! Fun pool that kids enjoyed. "
United States
Seth
The price is Rp2.243.537
Rp2.624.668 total
includes taxes & fees
2 Jun - 3 Jun
Drury Inn & Suites Southwest St. Louis
Exterior

Holiday Inn Express & Suites Wentzville St Louis West by IHG

Holiday Inn Express & Suites Wentzville St Louis West by IHG
2.5 star property
Wentzville
9.4 out of 10, Exceptional, (908 reviews)
"Very nice place to stay. Staff was super friendly. Clean, nice breakfast. "
United States
Patty
The price is Rp2.454.060
Rp2.920.859 total
includes taxes & fees
14 Jun - 15 Jun
Holiday Inn Express & Suites Wentzville St Louis West by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Stay near popular Defiance attractions

Photo by Pages of Travel
Open Photo by Pages of Travel

Chandler Hill Vineyards

3.9/5 (7 reviews)
This elegant Missouri winery showcases local and California wines from its hillside setting. Savour varietals on the expansive terrace while enjoying vineyard views and seasonal cuisine from their full-service kitchen.
See properties

Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

See all hotels in Defiance
A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri

Top Defiance Hotel Reviews

Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield

10/10 Excellent
"Good hotel"
Alan 2-night trip
Posted 1 hour ago
Drury Plaza Hotel St. Louis Chesterfield

More cheap stays in Defiance

Motel 6 Maryland Heights, MO

Motel 6 Maryland Heights, MO

12330 Dorsett Rd Maryland Heights MO
The price is Rp1.048.560 per night from 17 May to 18 May
Rp1.048.560
Rp1.216.204 total
17 May - 18 May
includes taxes & fees
6.2/10 (1,000 reviews)

Frequently asked questions

What's the best place to stay in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham, located 17.9 mi (28.8 km) from the heart of Defiance, is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are Hollywood Casino & Hotel St. Louis and Ameristar Casino Resort and Spa. See all available top hotels, or vacation rentals in Defiance.
If I need to cancel my hotel reservation in Defiance, will I receive a refund?
Yes! The majority of room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.
What are some accommodation options with pools in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham: Features an indoor pool, an outdoor pool and buffet. Ameristar Casino Resort and Spa and The Wildwood Hotel are two additional hotels with an on-site pool. View all hotels with pools in Defiance.
How is it staying in Defiance?
Visitors can enjoy all that Defiance has to offer, including the wineries and parks. Top sights in the area include St. Louis Union Station, Busch Stadium and Gateway Arch. In Defiance, there are 19 hotels and other accommodation options to choose from. Find out more about Defiance.
What should I do while I'm visiting Defiance?
Natural beauty is on display at August A. Busch Memorial Conservation Area, Missouri River and Matson Hill Park Trailhead. A couple of additional sights to add to your itinerary are Chandler Hill Vineyards and Sugar Creek Winery. Take a look at what more there is to see and do in Expedia's Defiance guide.
What's the weather like in Defiance?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.

Explore a world of travel with Expedia