Find the best Mississippi County Hotels
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Mississippi County Accommodation: Most Popular Cities to Stay
Charleston
East Prairie
Check prices for these dates
Our top choices for Mississippi County hotels
Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MOCharleston
6.8 out of 10, (624 reviews)
"Affordable for a quick one night stay. Restaurant and gas station next to hotel."
Annette
The price is Rp1.043.280
Rp1.157.688 total
includes taxes & fees
26 Mar - 27 Mar
The Riverstone Hotel Charleston-Sikeston
The Riverstone Hotel Charleston-SikestonCharleston
6.8 out of 10, (408 reviews)
"The staff was very friendly and accommodating "
Arturo
The price is Rp1.176.000
Rp1.305.066 total
includes taxes & fees
10 Mar - 11 Mar
Eagle Inn Charleston
Eagle Inn CharlestonCharleston
6.6 out of 10, (105 reviews)
"Convenient "
Marcelle
The price is Rp1.071.672
Rp1.189.440 total
includes taxes & fees
27 Feb - 28 Feb
Quality Inn Cairo I-57
Quality Inn Cairo I-57Cairo
6.6 out of 10, (282 reviews)
"The quality was not what I expected for a "Quality Inn". It felt more light a Motel 6. I was not satisfied at all."
ReShena
The price is Rp1.144.584
Rp1.270.259 total
includes taxes & fees
6 Mar - 7 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Mississippi County Hotel Reviews
Drury Inn & Suites Sikeston, MO
10/10 Excellent
Explore a world of travel with Expedia
Top cities in Mississippi County
Hotels near popular Attractions
More accommodation types in Mississippi County
Explore more hotels
- Super 8 by Wyndham Charleston/Sikeston East MO
- Drury Inn & Suites Sikeston, MO
- Sleep Inn at Discovery Park of America
- Best Western Plus Sikeston
- Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
- Days Inn and Suites by Wyndham Sikeston
- Reelfoot Lake Inn
- Hampton Inn Union City
- Quality Inn Union City US 51
More ways to book
Expedia's Latest Trends
Hotels
- Gay-Friendly Hotels in Lemay
- Hotels in Umber View Heights
- Hotels in Bellerive Acres
- Gay-Friendly Hotels in Power and Light District
- Hotels near World Wide Technology Raceway
- Hotels in Loma Linda
- Hotels in Tarrytown
- La Quinta Inn & Suites Hotels in Fleming Park
- Hotels in Danville
- Hotels in Fenton
- Hotels in Shawnee Bend
- Hotels in West Quincy
- Hotels in Downtown Springfield
- Hotels in Jeff-Vander-Lou
- Gay-Friendly Hotels in Downtown Branson
- Hotels near Quail Ridge Park
- Hotels in Greene County
- Hotels in Douglas County
- Hotels in Holt County
