What is Downtown West like?

Travellers are sure to enjoy a stay in St. Louis's Downtown West neighbourhood. Experience the best of Downtown West with a visit to St. Louis Union Station and Enterprise Center during your trip.

Where is the best hotel for a stay in Downtown West?

Based on Expedia customer reviews, Drury Inn & Suites St. Louis Union Station is the highest ranked property in Downtown West. This hotel is a short 5-minute walk from St. Louis Union Station, and it offers free breakfast and a restaurant. Other top choices in the neighbourhood include 21C Museum Hotel St Louis and Fairfield Inn & Suites by Marriott St. Louis Downtown .

How many hotels will I find in the Downtown West area?

If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 38 Downtown West hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in Downtown West, will I receive a refund?

Yes, you'll find most hotel room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within 24 hours of your booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to review top deals in Downtown West.

What is there to do in this St. Louis neighbourhood?

Browse the collections at City Museum, Campbell House Museum or Soldiers Memorial Museum in Downtown West. St. Louis Union Station and Enterprise Center are some other stops worth a visit in the neighbourhood. Busch Stadium and Gateway Arch are some popular places to visit in the area around Downtown West. While you're out sightseeing, Whispering Arch at Union Station and St. Louis Aquarium at Union Station are a couple of additional sights to visit in St. Louis.

How can I get around Downtown West and the greater St. Louis area?

To venture out of town, take a train from St. Louis Gateway Station.

The Best Hotels in Downtown West, St. Louis - 2026 Updated Prices

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Our top choices for Downtown West hotels

Drury Inn & Suites St. Louis Union Station

Downtown West

Anne Elizabeth

Rp2.742.644 total

includes taxes & fees

5 Apr - 6 Apr

Fairfield Inn & Suites by Marriott St. Louis Downtown

Downtown West

Frank

Rp2.405.245 total

includes taxes & fees

14 Apr - 15 Apr

Courtyard by Marriott St. Louis Downtown West

Downtown West

Lisa

Rp2.300.144 total

includes taxes & fees

29 Mar - 30 Mar

St. Louis Union Station Hotel, Curio Collection by Hilton

Downtown West

Amanda

Rp3.886.370 total

includes taxes & fees

22 Mar - 23 Mar

Home2 Suites by Hilton St. Louis Downtown

Downtown West

Catherine

Rp1.934.898 total

includes taxes & fees

31 Mar - 1 Apr

21C Museum Hotel St Louis

Downtown West

Eric

Rp2.596.110 total

includes taxes & fees

5 Apr - 6 Apr

Tru By Hilton St. Louis Downtown

Downtown West

Jenifer

Rp1.779.240 total

includes taxes & fees

31 Mar - 1 Apr

Pear Tree Inn St. Louis Near Union Station

Downtown West

Kyle

Rp2.101.656 total

includes taxes & fees

5 Apr - 6 Apr

Hilton St. Louis Frontenac

17.3 km from Downtown West

irene

Rp2.899.497 total

includes taxes & fees

5 Apr - 6 Apr

Motel 6 Hazelwood, MO

22.4 km from Downtown West

Andre

Rp1.240.139 total

includes taxes & fees

29 Mar - 30 Mar

Drury Inn & Suites Southwest St. Louis

27.2 km from Downtown West

Emilia

Rp2.281.267 total

includes taxes & fees

3 Apr - 4 Apr

The Principal Hotel

20.9 km from Downtown West

Paulina

Rp2.123.142 total

includes taxes & fees

18 Mar - 19 Mar

Comfort Suites St Charles - St Louis

29.2 km from Downtown West

Elizabeth

Rp1.640.026 total

includes taxes & fees

5 Apr - 6 Apr

Embassy Suites by Hilton St. Louis St. Charles

30 km from Downtown West

Jon Michael

Rp2.381.204 total

includes taxes & fees

5 Apr - 6 Apr

Casino Queen Hotel

2.7 km from Downtown West

Mary

Rp1.655.052 total

includes taxes & fees

16 Mar - 17 Mar

Country Inn & Suites by Radisson, St. Charles Historic District

29 km from Downtown West

Jean

Rp2.350.413 total

includes taxes & fees

22 Mar - 23 Mar

Drury Inn & Suites St. Louis Collinsville

18 km from Downtown West

Evonne

Rp2.164.117 total

includes taxes & fees

5 Apr - 6 Apr

Holiday Inn Express & Suites Edwardsville by IHG

26.7 km from Downtown West

Denise

Rp2.846.753 total

includes taxes & fees

5 Apr - 6 Apr

SpringHill Suites St. Louis Brentwood

11.2 km from Downtown West

Tyson

Rp2.240.942 total

includes taxes & fees

2 Apr - 3 Apr

Drury Plaza Hotel St. Louis St. Charles

29 km from Downtown West

John Christopher

Rp2.830.684 total

includes taxes & fees

3 Apr - 4 Apr

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Where to stay in Downtown West

Find the best Downtown West areas for the activities you enjoy most.

Gateway Arch featuring a monument, night scenes and a park

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Busch Stadium to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

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Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

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Berkeley

Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.

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Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

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Anheuser-Busch Brewery featuring heritage architecture and a garden

Soulard

You'll enjoy the bars and churches in Soulard. You might want to make time for a stop at Anheuser-Busch Brewery or Soulard Farmer's Market.

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Top Downtown West Hotel Reviews

Hotel Indigo St Louis - Central West End by IHG

8/10 Good

"This hotel was in an excellent location. The staff was efficient and attentive. Our only complaint was the food in the onsite restaurant, the BelAir Social. The food was edible, but nothing special for the price. The service was subpar at best. We were sitting at the bar and had to request service every time we needed something and the workers were standing two feet away on an evening when it wasn’t particularly busy. If you want great food just walk across the street to Yellowbelly. "