Southern Illinois Holiday Rentals, Illinois: Private House Rentals

A forested valley with autumn foliage, a rocky cliff, and a sunset.

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Our top choices for Southern Illinois hotels

A bar area with a long counter, multiple chairs, and hanging light fixtures.

A spacious lobby with a reception desk, seating area, and glass doors leading outside.

A hotel lobby with a Kitchen+Bar area, seating arrangements, and a view to the outside.

A hotel room with two beds, a desk with a flat-screen TV, a chair, and a lamp.

1. Drury Plaza Hotel Mt. Vernon

Mount Vernon

Kirstyn

Rp1.987.054

Rp2.241.039 total

includes taxes & fees

11 Oct - 12 Oct

An indoor swimming pool with a clear view of the surrounding area, including a seating area with chairs and a view of the outdoors through large windows.

A spacious dining area with a long wooden table, multiple chairs, and pendant lighting.

A hotel room with a large bed, two bedside tables with lamps, a desk with a chair, a television, and a framed artwork on the wall.

A hotel room with a desk, two monitors, a keyboard, and a mouse.

2. Best Western Delta Inn

Effingham

Susan

Rp1.604.109

Rp1.796.387 total

includes taxes & fees

4 Oct - 5 Oct

A hotel room with two beds, a desk, a chair, a TV, and a lamp.

A modern kitchen with a coffee station, seating area with tables and chairs, and a clock on the wall.

A reception area with a wooden counter, a television, and a sign reading "Baymont by Wyndham".

A compact kitchen with a refrigerator, a coffee maker, and a sink.

3. Baymont by Wyndham Effingham

Effingham

Jeffrey

Rp1.369.759

Rp1.520.159 total

includes taxes & fees

7 Oct - 8 Oct

A Country Inn & Suites building with a covered entrance and a sign.

A hotel room with a large bathtub, a bed with a dark headboard, two bedside tables with lamps, and a mirror above the bathtub.

A building with a green roof, white columns, and a glass entrance.

An indoor swimming pool with clear lane markings, a lifeguard chair, and a no diving sign.

4. Country Inn & Suites by Radisson, Effingham, IL

Effingham

Larry

Rp1.545.389

Rp1.715.072 total

includes taxes & fees

25 Oct - 26 Oct

A hotel room with a bed, bedside table, chair, and artwork on the walls.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A Holiday Inn Express & Suites hotel with a brick facade and a covered entrance.

A hotel room with a blue sofa, a bed with white bedding, a nightstand, a desk with a chair, and a large window offering a view.

5. Holiday Inn Express & Suites Vandalia by IHG

Vandalia

Scott

Rp2.184.166

Rp2.380.383 total

includes taxes & fees

18 Oct - 19 Oct

A cozy living room with a stone fireplace, leather sofas, and a flat-screen TV.

A bar area with a stone wall, a flat-screen TV, and a variety of bottles and glasses on shelves.

A living room with a stone fireplace, two round tables, and a sofa.

A spacious hotel lobby with a bar area, seating arrangements, and a kitchen in the background.

6. Cobblestone Inn & Suites - Altamont

Altamont

Heidi

Rp1.933.345

Rp2.087.669 total

includes taxes & fees

4 Oct - 5 Oct

A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

A hotel room with a desk, a lamp, a flat-screen TV, a telephone, a microwave, and a trash bin.

A breakfast area with a Superstart breakfast sign, a coffee machine, a refrigerator, and a bowl of fruit on the counter.

A parking lot with a Super 8 sign, a white car, and a truck.

7. Super 8 by Wyndham Mt. Vernon IL

Mount Vernon

Devin

Rp1.306.919

Rp1.486.225 total

includes taxes & fees

11 Oct - 12 Oct

An outdoor seating area with a fire pit, surrounded by wooden chairs and a view of a sunset over a landscaped garden.

A hotel room with a large bed, a wooden headboard, a nightstand, a desk, a chair, and a painting on the wall.

A multi-story hotel with a stone facade, a covered entrance, and a parking lot.

A modern living room with a grey sofa, two blue armchairs, a coffee table, and a TV mounted on the wall.

8. Best Western Plus Parkside Inn & Suites

Olney

Chandra

Rp2.267.415

Rp2.516.377 total

includes taxes & fees

5 Oct - 6 Oct

A banquet hall with tables set for a formal event, draped with white fabric and string lights, and a chandelier above.

A Holiday Inn lobby with a reception desk, two armchairs, and a decorative ceiling light.

A bar area with a long counter, multiple stools, and a television screen.

9. Holiday Inn Effingham by IHG

Effingham

Penny

Rp2.049.492

Rp2.295.021 total

includes taxes & fees

26 Oct - 27 Oct

A hotel room with a large bed, a separate desk with a chair, a TV, a bathroom with a bathtub, and a window with curtains.

A hotel lobby with a reception desk, a blue sofa, a red chair, and a breakfast area.

A multi-story hotel with a covered entrance, a wheelchair accessibility symbol, and a landscaped front yard.

An indoor swimming pool with a tiled floor, poolside chairs, and a table with chairs.

10. Comfort Suites Mattoon East

Mattoon

chris

Rp1.582.625

Rp1.772.223 total

includes taxes & fees

19 Oct - 20 Oct

An indoor swimming pool area with multiple lanes, lounge chairs, and a small seating area.

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

A lobby with patterned sofas, a fireplace, and framed pictures on the wall.

A lobby with two armchairs, a lamp, a framed artwork, and a sign indicating a fitness center.

11. Drury Inn & Suites St. Louis O'Fallon, IL

O'Fallon

KEVIN

Rp1.825.927

Rp2.117.710 total

includes taxes & fees

12 Oct - 13 Oct

A restaurant with multiple tables and booths, large windows, and a modern interior design.

A neatly made bed with white linens and a dark headboard, flanked by two bedside tables with lamps.

A wooden wall with the sign "THE PRINCIPAL HOTEL" and a row of books below.

A modern kitchen with a central island, bar stools, and a dining area.

12. The Principal Hotel

Columbia

Kenny

Rp1.756.284

Rp1.949.125 total

includes taxes & fees

30 Sept - 1 Oct

A lobby with a wooden staircase, a desk with a computer, and patterned armchairs.

A Ramada hotel with a brick facade, large entrance, and a clear sky.

A hotel room with a large bed, two bedside tables, a nightstand, and a lamp on each side.

A kitchen with white cabinets, a microwave, a coffee machine, and a refrigerator.

13. Ramada by Wyndham Vandalia

Vandalia

Samantha

Rp1.450.143

Rp1.580.298 total

includes taxes & fees

11 Oct - 12 Oct

A modern living room with a fireplace, a bookshelf, a large wall clock, and a cozy seating area.

A modern living room with a sofa, coffee table, and a dining area with chairs.

A reception area with a wooden counter, a welcome mat, and framed artwork on the wall.

An indoor swimming pool with clear water, surrounded by white lounge chairs and tables, with a high ceiling and natural light from windows.

14. Country Inn & Suites by Radisson, Marion, IL

Marion

Lisa

Rp1.646.785

Rp1.975.812 total

includes taxes & fees

25 Oct - 26 Oct

A modern hotel room with a large bed, a desk with a computer, a chair, a large window, a bathroom with a bathtub, and a green accent wall.

A modern hotel room with a flat-screen TV, a dark wooden desk, a blue sofa, a small dining table, and a kitchenette.

A Holiday Inn Express building with a covered entrance and a stone facade.

15. Holiday Inn Express & Suites Effingham by IHG

Effingham

Kimberly

Rp2.337.140

Rp2.617.057 total

includes taxes & fees

26 Oct - 27 Oct

A hotel with a covered entrance, a sign indicating it is now open, and a sign for the Cobblestone Hotel & Suites.

A bar area with a counter, bar stools, a television screen displaying a welcome message, and a wall-mounted dispenser.

A hotel room with a bed, a desk with a computer, a chair, a desk lamp, a TV, and a bathtub.

A hotel lobby with a reception desk, a seating area with tables and chairs, and a carpet with the hotel's name.

16. Cobblestone Hotel & Suites - Newton

Newton

Dawn

Rp2.094.472

Rp2.324.526 total

includes taxes & fees

30 Sept - 1 Oct

A La Quinta hotel with a stone facade, a covered entrance, and a parking lot.

A modern hotel lobby with a large sun-shaped artwork, multiple seating areas, and a patterned rug.

A hotel room with a large bed, a desk with a chair, a flat-screen TV, a bathtub, and framed pictures on the wall.

An indoor swimming pool with lounge chairs and a clear view of the pool area.

17. La Quinta Inn & Suites by Wyndham Effingham

Effingham

Alexis

Rp1.978.461

Rp2.215.480 total

includes taxes & fees

4 Oct - 5 Oct

A modern dining area with multiple tables and chairs, a kitchen area with appliances, and a ceiling with recessed lighting and a circular light fixture.

A modern hotel room with a living area, a kitchenette, and a door leading to another room.

A spacious lobby with a modern design, featuring a large seating area with leather chairs, a kitchen area with a counter and appliances, and a flat-screen TV mounted on the wall.

A spacious lobby with a stone reception desk, leather seating, and a large window offering a view of the outdoors.

18. Best Western Plus MidAmerica Hotel

Mascoutah

Danny

Rp1.961.274

Rp2.235.401 total

includes taxes & fees

4 Oct - 5 Oct

A modern kitchen with wooden cabinets, a refrigerator, a coffee machine, and a microwave. There are red chairs and a table in the dining area.

A reception area with a desk, chairs, a red carpet, and a television mounted on the wall.

A laundry area with two washers and dryers, a coin-operated machine, and a sign indicating the coin slot locks out when empty.

A hotel room with two beds, a nightstand, a lamp, and a framed picture on the wall.

19. Quality Inn Mount Vernon, IL

Mount Vernon

Matthew

Rp1.353.467

Rp1.537.883 total

includes taxes & fees

11 Oct - 12 Oct

A modern living room with a fireplace, blue sofa, red chairs, and a flat-screen TV mounted on a textured wall.

A hotel room with a blue armchair, a sofa, a bed, a desk, a television, and a window.

A hotel reception area with a computer desk, a printer, a coffee machine, and a framed cityscape picture on the wall.

A hotel reception area with a long wooden counter, coffee machines, and a wall with framed pictures.

20. Comfort Inn & Suites Greenville I-70

Greenville

Debbie

Rp1.776.515

Rp1.971.576 total

includes taxes & fees

18 Oct - 19 Oct

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Holiday Rentals in Southern Illinois

Cottage

A covered porch with blue plastic chairs, a ceiling fan, and large windows offering a view of the outdoors.

A kitchen with wooden cabinets, a microwave, a dishwasher, and a dining area with chairs and a table.

A bedroom with a bed, a nightstand, a mirror, a ceiling fan, and a door leading to a bathroom.

A kitchen with wooden cabinets, a checkered backsplash, a sink, and a dining area with chairs and a table.

Harrisburg Home w/ Private Yard + Screened Porch!

Harrisburg

"We love how accommodating, helpful and responsive Hollie and Clayton were. The rental had everything we needed and then some. Very clean, cozy and comfortable. We chose this location, because it was close to the different parks and trails we had visited. Thank you, Hollie and Clayton, for being such gracious hosts."

Cottage

A modern kitchen with white cabinetry, a coffee maker, a sink, a dishwasher, and a built-in oven.

A hallway with a white door, a mirror, a lamp, and a basket on a console table.

A two-story house with a well-maintained lawn and patio furniture.

A living room with a beige sectional sofa, a wooden coffee table, a patterned rug, and a small side table with a lamp.

Country Home Near EIU & Lake Charleston!

Charleston

"Property was very clean and beautifully decorated in a farmhouse style. Very cozy and comfortable! Came stocked with everything you would need. We had fun at nearby Aikman Wildlife Adventure in Arcola, Kayaking in Lake Charleston, hiking in Fox Ridge State Park a visit to Amish country in Arthur, IL. The kitchen, living and dining room were very spacious! The bathroom was very tiny so if staying with 4 adults - be prepared for this. Also there was a strange odor right outside the front entry...

Cottage

A modern kitchen with dark cabinets, a round dining table, and a tufted bench.

A modern living room with a flat-screen TV, wooden entertainment unit, leather sofa, and a dining table.

A single-story house with a front porch, a mailbox, and a wreath on the door.

A bedroom with a bed, a chair, a window, and two framed pictures on the wall.

Peaceful Robinson Home w/ Yard, Near Golf Courses!

Robinson

Cottage

A long, narrow hallway with wooden floors and large windows.

A single-story house with a front porch, a central entrance, and a small staircase leading to the door.

A modern kitchen with a stainless steel refrigerator, oven, and dishwasher. There is a wooden dining table and a brick accent wall.

A modern kitchen with white cabinets, a stainless steel refrigerator, and a tiled floor.

Cozy Anna Home Near Southern Illinois Attractions!

Anna

"Good communication with the owners. Nice perks such as coffee, tea, and hygiene items."

Cottage

A living room with a fireplace, leather sofas, and a clock on the wall.

A modern kitchen with wooden cabinets, a white refrigerator, and a microwave. There is a dining area with a table and chairs, and a living room with a couch and a fireplace.

A room with a wooden wall, a window with a view of a deck and outdoor area, and a potted plant with flowers on a table.

A spacious living room with leather sofas, a dining table, and a ceiling fan.

Illinois Vacation Rental Home: Pets Welcome

Palestine

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Stay near popular Southern Illinois attractions

Garden of the Gods Recreation Area

9.8/10 (63 reviews)

See for yourself why Harrisburg’s unearthly sandstone formations, tucked within lush Shawnee National Forest, earn their ethereal name.

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World Wide Technology Raceway

9.0/10 (2 reviews)

Catch an event at World Wide Technology Raceway during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

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O'Fallon Family Sports Park

8.6/10 (137 reviews)

This sports complex features premium turf fields, splash pads, and fishing ponds in a family-friendly setting. Watch tournaments or enjoy the scenic walking trail that winds around natural areas.

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Learn more about Southern Illinois

Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.

See all hotels in Southern Illinois

Top Southern Illinois Hotel Reviews

Drury Inn & Suites St. Louis O'Fallon, IL

10/10 Excellent

"Fabulous that I arrived & had Happy Hour Meal with Drinks & a great breakfast! Thx! Dennis D."

Country Inn & Suites by Radisson, Effingham, IL

10/10 Excellent

"GREAT PLACE! Comfortable beds, great pillow, excellent breakfast with extended hours compared to other places I've stayed. Would definitely stay again."

Quality Inn & Suites Metropolis I-24

8/10 Good

"Serves breakfast. But only thing they had was waffles, toast, apples and yogurt. Room was clean, bathroom looked like had mold on walls. Bathtub looked nasty. Didnt even use it. Cause checked in late and left early."

Ramada by Wyndham Effingham

10/10 Excellent

"It is a modest hotel with helpful staff, easily accessible handicapped parking, and surprisingly good scrambled eggs :)"

Comfort Inn Edwardsville - St. Louis

10/10 Excellent

"Property was well maintained. The room was clean and the bed was comfortable. The shower looked a little worn in some spots but it was fine overall. Room was cool and you could control the temperature. The breakfast was great and a nice touch every morning. Food was fresh and hot. Staff was friendly. We came for family weekend and we would stay again."

Walker's Bluff Casino Resort

10/10 Excellent

"The staff were very kind and helpful! The security guard even noticed my trunk was opened and closed it for me. I’ve stayed twice and both times the hotel and room was very clean and staff were friendly and welcoming. My only two complaints would be that the music in the lobby is loud and annoying and that the breakfast isn’t worth the price. But those things won’t keep from staying again when I’m in the area. I think the hotel clerk was Miranda in the evening and she was above and beyond friendly!"

Radisson Hotel Fairview Heights - St. Louis

8/10 Good

"Our stay at the Radisson was good overall and the prices are good . The location was convenient to restaurants and shopping .The first room had a wet carpet smell and the front desk was notified and immediately moved us to another room . The bed was comfortable, the bar inside was nice and reasonably priced. The property was clean and everyone was friendly . My only complaint would be our towels had stains on them and the room had minor spots and stains in certain areas but overall the stay was nice and we would definitely stay again ."

Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

10/10 Excellent

"not full and quiet for a casino environment."

Baymont by Wyndham Effingham

10/10 Excellent

"Perfect service. Clean! Great value and excellent place to stop while traveling."

More cheap stays in Southern Illinois

Americas Best Value Inn Collinsville St. Louis

552 Ramada Blvd Collinsville IL

Rp942.235

Rp1.083.490 total

11 Oct - 12 Oct

includes taxes & fees

6.4/10 (977 reviews)

Super 8 by Wyndham O'Fallon

1100 Eastgate Dr O'Fallon IL

Rp958.706

Rp1.102.320 total

21 Oct - 22 Oct

includes taxes & fees

6.6/10 (1,115 reviews)

Quality Inn & Suites Metropolis I-24

2118 E 5th St Metropolis IL

Rp1.049.376

Rp1.218.351 total

26 Oct - 27 Oct

includes taxes & fees

7.6/10 Good! (1,003 reviews)

Baymont by Wyndham Effingham

1811 W Fayette Avenue Effingham IL

Rp1.369.759

Rp1.520.159 total

7 Oct - 8 Oct

includes taxes & fees

8.2/10 Very good! (1,004 reviews)

Country Inn & Suites by Radisson, Effingham, IL

1200 N Raney Effingham IL

Rp1.545.389

Rp1.715.072 total

25 Oct - 26 Oct

includes taxes & fees

8.6/10 Excellent! (1,009 reviews)

Baymont by Wyndham Marion

2608 W Main St Marion IL

Rp1.724.989

Rp2.069.641 total

25 Oct - 26 Oct

includes taxes & fees

8.4/10 Very good! (1,095 reviews)

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Find hotels in Southern Illinois, IL from Rp1.083.490

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Southern Illinois

Check prices for these dates

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Our top choices for Southern Illinois hotels

1. Drury Plaza Hotel Mt. Vernon

2. Best Western Delta Inn

3. Baymont by Wyndham Effingham

4. Country Inn & Suites by Radisson, Effingham, IL

5. Holiday Inn Express & Suites Vandalia by IHG

6. Cobblestone Inn & Suites - Altamont

7. Super 8 by Wyndham Mt. Vernon IL

8. Best Western Plus Parkside Inn & Suites

9. Holiday Inn Effingham by IHG

10. Comfort Suites Mattoon East

11. Drury Inn & Suites St. Louis O'Fallon, IL

12. The Principal Hotel

13. Ramada by Wyndham Vandalia

14. Country Inn & Suites by Radisson, Marion, IL

15. Holiday Inn Express & Suites Effingham by IHG

16. Cobblestone Hotel & Suites - Newton

17. La Quinta Inn & Suites by Wyndham Effingham

18. Best Western Plus MidAmerica Hotel

19. Quality Inn Mount Vernon, IL

20. Comfort Inn & Suites Greenville I-70

Holiday Rentals in Southern Illinois

Harrisburg Home w/ Private Yard + Screened Porch!

Country Home Near EIU & Lake Charleston!

Peaceful Robinson Home w/ Yard, Near Golf Courses!

Cozy Anna Home Near Southern Illinois Attractions!

Illinois Vacation Rental Home: Pets Welcome

Stay near popular Southern Illinois attractions

Garden of the Gods Recreation Area

World Wide Technology Raceway

O'Fallon Family Sports Park

Learn more about Southern Illinois

Top Southern Illinois Hotel Reviews

Drury Inn & Suites St. Louis O'Fallon, IL

Country Inn & Suites by Radisson, Effingham, IL

Quality Inn & Suites Metropolis I-24

Ramada by Wyndham Effingham

Comfort Inn Edwardsville - St. Louis

Walker's Bluff Casino Resort

Radisson Hotel Fairview Heights - St. Louis

Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

Baymont by Wyndham Effingham

More cheap stays in Southern Illinois

Americas Best Value Inn Collinsville St. Louis

Super 8 by Wyndham O'Fallon

Quality Inn & Suites Metropolis I-24

Baymont by Wyndham Effingham

Country Inn & Suites by Radisson, Effingham, IL

Baymont by Wyndham Marion

Explore a world of travel with Expedia

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