What's it like in Lake Nona Medical City?

Lake Nona Medical City is a neighbourhood that travellers like for its restaurants.

What's the best accommodation in Lake Nona Medical City?

Based on Expedia customer reviews, Aloft Orlando Lake Nona is the highest ranked property in Lake Nona Medical City. This hotel offers a restaurant and an outdoor pool. Other favourite options in the area include Residence Inn Orlando Lake Nona and Courtyard Orlando Lake Nona .

How many hotels will I find in Lake Nona Medical City?

Expedia has 5 Lake Nona Medical City hotels and other accommodation options, and one might make a good home base for venturing out into the greater Orlando area.

If I need to cancel my hotel reservation in Lake Nona Medical City, will I receive a refund?

Yes, the majority of hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Lake Nona Medical City.

What is there to do around this Orlando neighbourhood?

Eagle Creek Golf Club, USTA National Campus and Austin-Tindall Regional Park are just a few of the places to visit in and around Lake Nona Medical City. When you're sightseeing around the area, Lake Hart and Moss Park are a couple of other sights to visit.

The Best Hotels in Lake Nona Medical City, Orlando - 2026 Updated Prices

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Our top choices for Lake Nona Medical City hotels

A swimming pool with sun loungers and palm trees.

1. Courtyard Orlando Lake Nona

Lake Nona Medical City

William

Rp2.960.184 total

includes taxes & fees

6 Sept - 7 Sept

A swimming pool with sun loungers and palm trees, surrounded by a modern building.

2. Residence Inn Orlando Lake Nona

Lake Nona Medical City

Edwin

Rp3.524.131 total

includes taxes & fees

6 Sept - 7 Sept

3. Aloft by Marriott Orlando Lake Nona

Lake Nona Medical City

Melissa

Rp2.799.150 total

includes taxes & fees

7 Sept - 8 Sept

A hotel atrium with a central fountain, palm trees, and a circular seating area.

4. Hyatt Regency Orlando International Airport

7.7 km from Lake Nona Medical City

William

Rp3.569.461 total

includes taxes & fees

7 Sept - 8 Sept

An outdoor seating area with green chairs and umbrellas, a fire pit, and a building with large windows in the background.

5. Hampton Inn & Suites Orlando Airport @ Gateway Village

Airport North, 10.6 km from Lake Nona Medical City

Katherine

Rp1.700.537 total

includes taxes & fees

31 Aug - 1 Sept

An outdoor patio area with seating, a bar, and a fire feature.

6. Hyatt House Orlando Airport

Airport North, 10.5 km from Lake Nona Medical City

Armando

Rp2.352.729 total

includes taxes & fees

6 Sept - 7 Sept

A modern restaurant with multiple dining tables and chairs, a bar area, and a television mounted on the wall.

7. Wingate by Wyndham - Orlando International Airport

Airport North, 11.1 km from Lake Nona Medical City

Ronda

Rp1.322.064 total

includes taxes & fees

21 Sept - 22 Sept

A modern hotel room with a large bed, a nightstand, a drawer, a wall-mounted light, and a window with a view of trees.

8. Ramada by Wyndham Suites Orlando Airport

Airport North, 10.4 km from Lake Nona Medical City

Dwayne

Rp1.576.127 total

includes taxes & fees

13 Sept - 14 Sept

A modern gym with treadmills, stationary bikes, and elliptical machines.

9. Wyndham Garden Orlando Airport

Belle Isle, 11.9 km from Lake Nona Medical City

Gabriel

Rp1.674.824 total

includes taxes & fees

9 Sept - 10 Sept

A spacious lobby with a wooden staircase, a reception desk, and a large wall clock.

10. Country Inn & Suites by Radisson, Orlando Airport, FL

Airport North, 11 km from Lake Nona Medical City

Adley

Rp1.542.232 total

includes taxes & fees

3 Sept - 4 Sept

A modern hotel lobby with a large flat-screen TV, a blue sofa, a round wooden table, and a curved reception desk.

11. Cambria Hotel Orlando Airport

11.1 km from Lake Nona Medical City

Juan

Rp1.932.029 total

includes taxes & fees

16 Sept - 17 Sept

A hotel with a prominent tower, palm trees, and a red roof.

12. La Quinta Inn & Suites by Wyndham Orlando Airport

Airport North, 10.9 km from Lake Nona Medical City

Maria

Rp1.419.612 total

includes taxes & fees

21 Sept - 22 Sept

A hotel room with two beds, a sofa, a small table, a lamp, and a framed abstract artwork on the wall.

13. Hyatt Place Orlando Airport

Airport North, 11 km from Lake Nona Medical City

Yahella

Rp2.016.766 total

includes taxes & fees

30 Aug - 31 Aug

A modern living room with a stone fireplace, a sofa, a coffee table, and a lamp.

14. Fairfield Inn By Marriott Orlando Airport

Airport North, 10.8 km from Lake Nona Medical City

keylin

Rp1.368.519 total

includes taxes & fees

31 Aug - 1 Sept

A modern dining area with a large table, chairs, and a coffee station.

15. avid hotel Orlando International Airport by IHG

11.2 km from Lake Nona Medical City

Breana

Rp1.734.834 total

includes taxes & fees

27 Sept - 28 Sept

A modern kitchen with wooden cabinets, a central island, and a breakfast bar.

16. Hampton Inn Orlando-International Airport

Airport North, 10.8 km from Lake Nona Medical City

Jorge

Rp1.782.092 total

includes taxes & fees

6 Sept - 7 Sept

A modern hotel with a red carpet leading to the entrance, a wooden walkway, and a clear view of the building's facade.

17. EVEN Hotel Orlando International Airport by IHG

Airport North, 11.1 km from Lake Nona Medical City

Aaron

Rp1.774.717 total

includes taxes & fees

24 Sept - 25 Sept

A reception area with a pool view mural, two reception desks, and a waiting area with chairs.

18. La Quinta Inn & Suites by Wyndham Orlando UCF

25.4 km from Lake Nona Medical City

Cecile

Rp1.626.971 total

includes taxes & fees

7 Sept - 8 Sept

A hotel room with two beds, a flat-screen TV, a desk, and a lamp.

19. Sonesta Essential Orlando Airport

12.2 km from Lake Nona Medical City

Jasmine

Rp1.774.604 total

includes taxes & fees

30 Aug - 31 Aug

An aerial view of a resort with multiple swimming pools, landscaped gardens, and outdoor seating areas.

20. Rosen Shingle Creek

16.9 km from Lake Nona Medical City

Mariana

Rp2.376.655 total

includes taxes & fees

6 Sept - 7 Sept

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Where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas for the activities you enjoy most. Learn more about Lake Nona Medical City

The entrance to the Hollywood Studios area with a large sign and distinctive architecture.

Bay Lake

Exciting theme parks plentiful wildlife and top sights from Epcot® to Walt Disney World® Resort – discover Bay Lake, a destination also famous for its entertainment.

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The entrance to Aquatica with colorful signage and a water slide.

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

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A golf course with bunkers, water hazards, and a large lake.

Reunion

The top golf courses and fun-filled water parks are top of the list for many visitors to Reunion. A stop by Reunion Resort Golf Course or Jack Nicklaus Course might round out your trip.

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A roller coaster at Universal Orlando Resort, featuring a tall palm tree and a clear blue sky.

Florida Center

If you're spending some time in Florida Center, Universal Orlando Resort and Universal Studios Florida are top sights worth seeing.

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A large Ferris wheel with blue lighting, surrounded by a parking lot and buildings.

Champions Gate

Ample dining options and top golf courses are well-reviewed features of Champions Gate. Make a stop by top sights like ChampionsGate Golf Club while you're exploring the area.

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Top Lake Nona Medical City Hotel Reviews

Universal's Endless Summer Resort - Dockside Inn and Suites

10/10 Excellent

"Overall great stay"

Drury Plaza Hotel Orlando - Disney Springs Area

10/10 Excellent

"Excellent location with easy walking access to Disney Springs. The bus service was frequent, reliable, and very convenient. The hotel was modern, very clean, and well maintained. We especially enjoyed the great breakfast and afternoon snack selection. The staff were friendly, welcoming, and very helpful. Overall, a fantastic stay!"

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Our top choices for Lake Nona Medical City hotels

1. Courtyard Orlando Lake Nona

2. Residence Inn Orlando Lake Nona

3. Aloft by Marriott Orlando Lake Nona

4. Hyatt Regency Orlando International Airport

5. Hampton Inn & Suites Orlando Airport @ Gateway Village

6. Hyatt House Orlando Airport

7. Wingate by Wyndham - Orlando International Airport

8. Ramada by Wyndham Suites Orlando Airport

9. Wyndham Garden Orlando Airport

10. Country Inn & Suites by Radisson, Orlando Airport, FL

11. Cambria Hotel Orlando Airport

12. La Quinta Inn & Suites by Wyndham Orlando Airport

13. Hyatt Place Orlando Airport

14. Fairfield Inn By Marriott Orlando Airport

15. avid hotel Orlando International Airport by IHG

16. Hampton Inn Orlando-International Airport

17. EVEN Hotel Orlando International Airport by IHG

18. La Quinta Inn & Suites by Wyndham Orlando UCF

19. Sonesta Essential Orlando Airport

20. Rosen Shingle Creek

Where to stay in Lake Nona Medical City

Bay Lake

International Drive District

Reunion

Florida Center

Champions Gate

Top Lake Nona Medical City Hotel Reviews

Universal's Endless Summer Resort - Dockside Inn and Suites

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