Search Hotels Near Main Street Hyannis, Hyannis

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Check prices for these dates

Tonight
14 Dec - 15 Dec
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15 Dec - 16 Dec
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19 Dec - 21 Dec
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26 Dec - 28 Dec

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Our top choices for Main Street Hyannis hotels

Terrace/patio
Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging
3.0 star property
0.6 km from Main Street Hyannis
9.4 out of 10, Exceptional, (1002)
"Staff member Sandy very congenial when we checked in. Laid back atmosphere (early December). Will consider for future Hyannis stay."
United States
Lawrence
The price is Rp2.319.924
Rp3.131.394 total
includes taxes & fees
16 Dec - 17 Dec
Anchor In Distinctive Waterfront Lodging
Lobby
Fairfield Inn & Suites by Marriott Cape Cod Hyannis

Fairfield Inn & Suites by Marriott Cape Cod Hyannis

Fairfield Inn & Suites by Marriott Cape Cod Hyannis
2.5 star property
2.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (657)
"Great people, nice breakfast "
United States
Lorri
The price is Rp1.614.662
Rp1.847.982 total
includes taxes & fees
11 Jan - 12 Jan 2026
Fairfield Inn & Suites by Marriott Cape Cod Hyannis
View from property
Courtyard By Marriott Cape Cod Hyannis

Courtyard By Marriott Cape Cod Hyannis

Courtyard By Marriott Cape Cod Hyannis
3.0 star property
1.7 km from Main Street Hyannis
8.8 out of 10, Excellent, (486)
"Pretty nice location"
United States
Saulius
The price is Rp2.036.805
Rp2.331.123 total
includes taxes & fees
4 Jan - 5 Jan 2026
Courtyard By Marriott Cape Cod Hyannis
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers
Bayside Resort Hotel

Bayside Resort Hotel

Bayside Resort Hotel
3.0 star property
2.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (1524)
"excellent quality of food. Pool and hot tub fabulous"
United States
Deborah
Bayside Resort Hotel
Exterior
Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis
4.0 star property
1 km from Main Street Hyannis
8.4 out of 10, Very good, (878)
"Nice room, freindly staff. The downside is the food was pricey. "
United States
Steffanie
The price is Rp1.719.865
Rp1.968.385 total
includes taxes & fees
11 Jan - 12 Jan 2026
Doubletree by Hilton Cape Cod - Hyannis
Exterior
Cape Sands Inn

Cape Sands Inn

Cape Sands Inn
2.5 star property
1.9 km from Main Street Hyannis
8.2 out of 10, Very good, (1016)
"Clean room courteous staff and easy check in "
United States
Linda
The price is Rp1.241.625
Rp1.421.069 total
includes taxes & fees
15 Dec - 16 Dec
Cape Sands Inn
Exterior
Holiday Inn Hyannis by IHG

Holiday Inn Hyannis by IHG

Holiday Inn Hyannis by IHG
3.0 star property
2.9 km from Main Street Hyannis
8.2 out of 10, Very good, (977)
"Check in was easy and the front desk person was wonderful. "
United States
Anastasios
The price is Rp1.781.122
Rp2.038.494 total
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Hyannis by IHG
Free daily continental breakfast
Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod
2.5 star property
0.3 km from Main Street Hyannis
8.0 out of 10, Very good, (1001)
"Well appointed lodging with very friendly and attentive staff. Perfect central location with easy walk to many local sights as well as convenient access to ferry terminal. "
United States
Kerri
The price is Rp1.632.973
Rp1.868.938 total
includes taxes & fees
20 Dec - 21 Dec
Comfort Inn Hyannis - Cape Cod
Front of property
Hyannis Harbor Hotel

Hyannis Harbor Hotel

Hyannis Harbor Hotel
3.5 star property
0.6 km from Main Street Hyannis
8.0 out of 10, Very good, (1000)
"Amazing place "
United States
Mounir
The price is Rp2.079.918
Rp3.052.710 total
includes taxes & fees
16 Dec - 17 Dec
Hyannis Harbor Hotel
Lobby
Hyannis Plaza Hotel

Hyannis Plaza Hotel

Hyannis Plaza Hotel
2.5 star property
0.9 km from Main Street Hyannis
7.0 out of 10, Good, (968)
"good stay for night"
United States
David
The price is Rp1.211.662
Rp1.553.208 total
includes taxes & fees
12 Jan - 13 Jan 2026
Hyannis Plaza Hotel
Indoor pool
Courtyard Resort

Courtyard Resort

Courtyard Resort
2.0 star property
0.3 km from Main Street Hyannis
8.2 out of 10, Very good, (44)
"Room was very clean. Staff were courteous!"
United States
Timothy
The price is Rp1.814.414
Rp2.076.596 total
includes taxes & fees
4 Jan - 5 Jan 2026
Courtyard Resort
Family House, Private Bathroom, Pool View | Lounge
Sal's Place

Sal's Place

Sal's Place
2.0 star property
2.5 km from Main Street Hyannis
The price is Rp4.660.880
Rp7.331.897 total
includes taxes & fees
15 Dec - 16 Dec
Sal's Place
Garden
The Village Inn Cape Cod

The Village Inn Cape Cod

The Village Inn Cape Cod
3.5 star property
6.1 km from Main Street Hyannis
10.0 out of 10, Exceptional, (222)
"It was so charming, would definitely stay there again! "
United States
Kyle
The price is Rp2.813.174
Rp3.219.669 total
includes taxes & fees
15 Dec - 16 Dec
The Village Inn Cape Cod
Outdoor dining
Inn on Main

Inn on Main

Inn on Main
3.5 star property
6.4 km from Main Street Hyannis
10.0 out of 10, Exceptional, (73)
"We love staying here! Best dog B&B in America!"
United States
Barbara
The price is Rp4.540.113
Rp5.196.161 total
includes taxes & fees
15 Dec - 16 Dec
Inn on Main
Terrace/patio
Brewster by the Sea Inn

Brewster by the Sea Inn

Brewster by the Sea Inn
4.0 star property
17.4 km from Main Street Hyannis
9.8 out of 10, Exceptional, (171)
"Brewster By the Sea has it all - great location, amazing innkeeper, unbelievable breakfasts, and great rooms with perfect amenities. "
United States
Donna
The price is Rp5.293.428
Rp6.058.478 total
includes taxes & fees
1 Jan - 2 Jan 2026
Brewster by the Sea Inn
Property grounds
The Escape Inn

The Escape Inn

The Escape Inn
2.5 star property
7.6 km from Main Street Hyannis
9.4 out of 10, Exceptional, (656)
"clean, convenient and very easy check in/out. "
United States
chris
The price is Rp1.337.007
Rp1.530.267 total
includes taxes & fees
16 Dec - 17 Dec
The Escape Inn
Deluxe Suite, Oceanfront, 2 Bedrooms | Terrace/patio
Ocean Club on Smuggler's Beach

Ocean Club on Smuggler's Beach

Ocean Club on Smuggler's Beach
2.5 star property
6.9 km from Main Street Hyannis
9.2 out of 10, Wonderful, (1001)
"The Ocean Club is always a great place to stay. Very convenient location and a great place for a walk on the beach. "
United States
Steve
The price is Rp2.480.254
Rp3.015.589 total
includes taxes & fees
23 Dec - 24 Dec
Ocean Club on Smuggler's Beach
Oceanfront Efficiency, 1 King Bed | Premium bedding, down duvets, iron/ironing board, free WiFi
Chatham Tides

Chatham Tides

Chatham Tides
2.5 star property
20.9 km from Main Street Hyannis
9.4 out of 10, Exceptional, (668)
"We had such an amazing stay at Chatham Tides! The room was incredibly clean and very cozy. Check-in was easy and the staff was helpful and friendly. We were pleasantly surprised at the view and how quaint everything felt. We will definitely be visiting again!"
United States
Jessica
The price is Rp2.531.857
Rp2.897.736 total
includes taxes & fees
16 Dec - 17 Dec
Chatham Tides
Outdoor pool, pool umbrellas, pool loungers
Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod
4.0 star property
3.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (412)
"The entire place was spotless and rooom beet pleasant. Staff was super friendly and the Landshark Bar was excellent. Highly recommend a stay here ! "
United States
Stephen
Margaritaville Resort Cape Cod
Private beach nearby, beach bar
The Club at New Seabury

The Club at New Seabury

The Club at New Seabury
3.5 star property
19.4 km from Main Street Hyannis
9.0 out of 10, Wonderful, (339)
"Very relaxing, loved the different clubs available; beach, pool, tennis, playground for the little ones, bars and food. Some shops were closed due to being off season, but still enjoyed our stay. Looking forward to booking again "
United States
Jose O.
The Club at New Seabury
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Main Street Hyannis Hotel Reviews

Cape Sands Inn

Cape Sands Inn

10/10 Excellent
"Clean room courteous staff and easy check in "
Linda 1-night trip
Posted 4 days ago
Cape Sands Inn

Hotels near other Main Street Hyannis attractions

John F. Kennedy Hyannis Museum showcases bronze statue and historic architecture in Hyannis Massachusetts

John F. Kennedy Hyannis Museum

4.4/5 (259 reviews)
Learn about the 35th president of the United States at this revealing museum, which is just a short distance from the Kennedy Compound.
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Cape Cod Maritime Museum which includes a bay or harbor and signage

Cape Cod Maritime Museum

You can spend an afternoon studying the exhibits at Cape Cod Maritime Museum during your trip to Hyannis. Stroll along the beautiful beaches in this family-friendly area or visit its seafood restaurants.
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Frequently asked questions

What's the area like around Main Street Hyannis?
Main Street Hyannis is located in a walkable area of Hyannis known for its top seafood restaurants and major shopping area. If you're looking for a convenient place to stay, take a look at the 181 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near Main Street Hyannis?
Adjacent to Main Street Hyannis, Hyannis Travel Inn is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an outdoor pool. Other good options within a short distance include Courtyard Resort and Comfort Inn Hyannis - Cape Cod.
How many hotels can I expect to find near Main Street Hyannis?
Expedia has 181 hotels and other accommodation options within a mile from Main Street Hyannis.
If I need to cancel the hotel reservation for my stay near Main Street Hyannis, will I receive a refund?
Yes! Most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer near Main Street Hyannis.
What can I see and do near Main Street Hyannis?
John F. Kennedy Hyannis Museum, Whydah Pirate Museum and Cape Cod Maritime Museum feature captivating exhibits. Hyannis Harbor, Edward Gorey House and Sandy Neck Lighthouse are landmarks that you won't want to miss. You can enjoy live performances at Cape Cod Melody Tent and Barnstable Performing Arts Center.

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