A storefront with a sign reading "The Beach Club" and various clothing items displayed in the window.

Search Hotels Near Main Street Hyannis, Hyannis

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
31 Jul - 2 Aug
Next weekend
7 Aug - 9 Aug

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Main Street Hyannis hotels

Terrace/patio

1. Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging
3.0 star property
0.6 km from Main Street Hyannis
9.4 out of 10, Exceptional, (1,012 reviews)
"Staff was all very nice. Breakfast muffins were delightful. Location is great- easy to get to the hy line ferry. Would stay again."
United States
Kara
The price is Rp6.198.544
Rp7.611.302 total
includes taxes & fees
6 Aug - 7 Aug
Anchor In Distinctive Waterfront Lodging
Indoor pool, seasonal outdoor pool

2. Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection
4.0 star property
1.9 km from Main Street Hyannis
9.4 out of 10, Exceptional, (232 reviews)
"Great place to stay and the staff members are amazing."
United States
Joseph
The price is Rp5.566.484
Rp6.593.500 total
includes taxes & fees
30 Aug - 31 Aug
Uncommoner Hotel by Reverie Boutique Collection
View from property

3. Green Harbor Resort

Green Harbor Resort
3.0 star property
2.1 km from Main Street Hyannis
9.6 out of 10, Exceptional, (365 reviews)
"Wonderful resort, everything - amenities, grounds and rooms - so well taken care of."
United States
Douglas
The price is Rp8.033.059
Rp10.205.158 total
includes taxes & fees
26 Aug - 27 Aug
Green Harbor Resort
Exterior

4. Heritage House Inn on Cape Cod, an Ascend Collection Hotel

Heritage House Inn on Cape Cod, an Ascend Collection Hotel
2.5 star property
0.3 km from Main Street Hyannis
9.0 out of 10, Wonderful, (79 reviews)
"Nice hotel in a great area"
Canada
Gary
The price is Rp3.415.797
Rp3.909.380 total
includes taxes & fees
27 Aug - 28 Aug
Heritage House Inn on Cape Cod, an Ascend Collection Hotel
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers

5. Hampton Inn & Suites Cape Cod-West Yarmouth

Hampton Inn & Suites Cape Cod-West Yarmouth
2.5 star property
1.7 km from Main Street Hyannis
8.8 out of 10, Excellent, (1,001 reviews)
The price is Rp4.638.978
Rp5.309.305 total
includes taxes & fees
30 Aug - 31 Aug
Hampton Inn & Suites Cape Cod-West Yarmouth
Marina

6. Cape Cod Inn

Cape Cod Inn
2.0 star property
0.2 km from Main Street Hyannis
8.6 out of 10, Excellent, (529 reviews)
"Area is convenient and centrally located on the main road. Room was large but needs some TLC. Very reasonable priced for the area."
United States
James
The price is Rp2.204.906
Rp2.523.533 total
includes taxes & fees
17 Aug - 18 Aug
Cape Cod Inn
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers

7. Bayside Resort Hotel

Bayside Resort Hotel
3.0 star property
2.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (1,557 reviews)
"We stayed here for 4th of July weekend and it was wonderful!"
United States
Ashley
The price is Rp3.903.768
Rp4.674.799 total
includes taxes & fees
23 Aug - 24 Aug
Bayside Resort Hotel
Indoor pool

8. Courtyard Resort

Courtyard Resort
2.0 star property
0.3 km from Main Street Hyannis
8.6 out of 10, Excellent, (106 reviews)
"Second time here absolutely love this place"
United States
Meghan
The price is Rp3.415.797
Rp3.909.380 total
includes taxes & fees
2 Aug - 3 Aug
Courtyard Resort
Exterior

9. Cape Sands Inn

Cape Sands Inn
2.5 star property
1.9 km from Main Street Hyannis
8.2 out of 10, Very good, (1,115 reviews)
"Great location"
United States
Cleison
The price is Rp2.125.023
Rp2.431.903 total
includes taxes & fees
30 Aug - 31 Aug
Cape Sands Inn
Exterior

10. Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis
4.0 star property
0.9 km from Main Street Hyannis
8.4 out of 10, Very good, (929 reviews)
"Great property, centrally located, staff very helpful!"
United States
Melisa
The price is Rp4.088.836
Rp4.679.674 total
includes taxes & fees
30 Aug - 31 Aug
Doubletree by Hilton Cape Cod - Hyannis
Free daily continental breakfast

11. Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod
2.5 star property
0.3 km from Main Street Hyannis
8.2 out of 10, Very good, (1,002 reviews)
"Great location and extremely friendly service!"
United States
Chandler
The price is Rp2.911.560
Rp3.332.281 total
includes taxes & fees
27 Aug - 28 Aug
Comfort Inn Hyannis - Cape Cod
Exterior

12. Holiday Inn Hyannis by IHG

Holiday Inn Hyannis by IHG
3.0 star property
2.9 km from Main Street Hyannis
8.2 out of 10, Very good, (1,000 reviews)
"Great hotel for short stay"
United States
Lyuda
The price is Rp3.069.880
Rp3.513.391 total
includes taxes & fees
23 Aug - 24 Aug
Holiday Inn Hyannis by IHG
Front of property

13. Hyannis Harbor Hotel

Hyannis Harbor Hotel
3.5 star property
0.6 km from Main Street Hyannis
8.2 out of 10, Very good, (1,002 reviews)
"great location and great place"
United States
Rachel
The price is Rp4.863.083
Rp6.122.446 total
includes taxes & fees
2 Aug - 3 Aug
Hyannis Harbor Hotel
Reception

14. Hyannis Host Inn

Hyannis Host Inn
2.0 star property
1.6 km from Main Street Hyannis
8.0 out of 10, Very good, (494 reviews)
"Comfortable bed, clean bathroom, we enjoyed our stay"
United States
Kenneth
The price is Rp2.130.807
Rp2.438.709 total
includes taxes & fees
2 Aug - 3 Aug
Hyannis Host Inn
Indoor pool, seasonal outdoor pool, pool loungers

15. Americas Best Value Inn & Suites Hyannis Cape Cod

Americas Best Value Inn & Suites Hyannis Cape Cod
2.0 star property
0.5 km from Main Street Hyannis
7.8 out of 10, Good, (1,018 reviews)
"Pretty good place to stay with a good price"
United States
Kelly
The price is Rp2.150.687
Rp2.461.362 total
includes taxes & fees
23 Aug - 24 Aug
Americas Best Value Inn & Suites Hyannis Cape Cod
Beach

16. Sunbird Cape Cod Resort

Sunbird Cape Cod Resort
2.5 star property
2.3 km from Main Street Hyannis
7.8 out of 10, Good, (601 reviews)
"Breakfast was a pleasant surprise with many great options. Room was clean but had a bit of a musty smell but once the AC was on it was better. It is a simple hotel but overall we had a great time."
United States
Fernanda
The price is Rp2.256.130
Rp2.582.142 total
includes taxes & fees
30 Aug - 31 Aug
Sunbird Cape Cod Resort
Beach

17. Sunbird ANNEX Resort

Sunbird ANNEX Resort
2.0 star property
2.3 km from Main Street Hyannis
7.8 out of 10, Good, (884 reviews)
"Rooms were clean and staff was super helpful. The breakfast was phenomenal"
United States
Nashaiyaa
The price is Rp2.442.927
Rp2.795.893 total
includes taxes & fees
30 Aug - 31 Aug
Sunbird ANNEX Resort
Lobby

18. Hyannis Plaza Hotel

Hyannis Plaza Hotel
2.5 star property
0.9 km from Main Street Hyannis
7.2 out of 10, Good, (1,006 reviews)
"Great hotel, room was clean and really nice"
United States
Jackeline
The price is Rp3.614.600
Rp4.317.639 total
includes taxes & fees
13 Aug - 14 Aug
Hyannis Plaza Hotel
Lobby

19. Days Inn by Wyndham West Yarmouth/Hyannis Cape Cod Area

Days Inn by Wyndham West Yarmouth/Hyannis Cape Cod Area
2.0 star property
1.5 km from Main Street Hyannis
7.0 out of 10, Good, (1,019 reviews)
"Older building some what refreshed. Not close to Wyndham quality. More like a Day’s Inn."
United States
Nanda K
The price is Rp2.241.052
Rp2.564.884 total
includes taxes & fees
23 Aug - 24 Aug
Days Inn by Wyndham West Yarmouth/Hyannis Cape Cod Area
View from property

20. Ocean Street Inn on Hyannis Harbor

Ocean Street Inn on Hyannis Harbor
2.0 star property
0.4 km from Main Street Hyannis
7.0 out of 10, Good, (831 reviews)
"Close to being On the water with clean rooms. Lots of places to eat and the check in staff was awesome and plenty of parking"
United States
Greg
The price is Rp2.192.616
Rp2.760.302 total
includes taxes & fees
30 Aug - 31 Aug
Ocean Street Inn on Hyannis Harbor
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Main Street Hyannis

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Terrace/patio
Anchor In Distinctive Waterfront Lodging
3.0 star property
9.4
Exceptional
1,012 reviews
View
Indoor pool, seasonal outdoor pool
Uncommoner Hotel by Reverie Boutique Collection
4.0 star property
9.4
Exceptional
232 reviews
View
View from property
Green Harbor Resort
3.0 star property
9.6
Exceptional
365 reviews
View
Exterior
Heritage House Inn on Cape Cod, an Ascend Collection Hotel
2.5 star property
9.0
Wonderful
79 reviews
View
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers
Hampton Inn & Suites Cape Cod-West Yarmouth
2.5 star property
8.8
Excellent
1,001 reviews
View

Top Main Street Hyannis Hotel Reviews

Cape Sands Inn

Cape Sands Inn

8/10 Good
"Simple. Pleasant. I'd stay there again."
michael 1-night trip
Posted 1 hour ago
Cape Sands Inn

Other attractions near Main Street Hyannis

A bronze statue of a man in a polo shirt standing in front of a building with a brick facade, white columns, and an American flag.

John F. Kennedy Hyannis Museum

8.8/10 (444 reviews)
Learn about the 35th president of the United States at this revealing museum, which is just a short distance from the Kennedy Compound.
See properties

Frequently asked questions

What's the area like around Main Street Hyannis?
Main Street Hyannis is located in a walkable area of Hyannis known for its top seafood restaurants and major shopping area. If you're looking for a convenient place to stay, take a look at the 200 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near Main Street Hyannis?
Adjacent to Main Street Hyannis, Hyannis Travel Inn is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an outdoor pool. Other good options within a short distance include Hyannis Harbor Hotel and Hyannis Plaza Hotel.
How many hotels can I expect to find near Main Street Hyannis?
Expedia has 200 hotels and other accommodation options within a mile from Main Street Hyannis.
If I need to cancel the hotel reservation for my stay near Main Street Hyannis, will I receive a refund?
Yes! Most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer near Main Street Hyannis.
What can I see and do near Main Street Hyannis?
John F. Kennedy Hyannis Museum, Cape Cod Maritime Museum and Whydah Pirate Museum feature captivating exhibits. Hyannis Harbor, Edward Gorey House and Sandy Neck Lighthouse are landmarks that you won't want to miss. Local parks like Lewis Bay, Veterans Memorial Park and Dennis Pond Conservation Area are peaceful spots to stop and take in some fresh air.