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Our top choices for Maine Medical Center hotels

Reception
Longfellow Hotel

Longfellow Hotel

Longfellow Hotel
4.0 star property
Parkside, 0.3 km from Maine Medical Center
9.6 out of 10, Exceptional, (138)
"Very stylish, clean, and comfortable hotel. We typically stay in the Oldport section of Portland but it was really nice to explore other areas. Lots of restaurants, bars, and coffee shops in the area. The hotel bar and coffee shop are great and very convenient. Look for those week day deals. Very affordable "
United States
Rachel
Longfellow Hotel
Deluxe Suite, 1 King Bed | Living area | LCD TV, Netflix, streaming services, music library
The Weldon Hotel

The Weldon Hotel

The Weldon Hotel
4.5 star property
Downtown Portland, 1.4 km from Maine Medical Center
9.8 out of 10, Exceptional, (89)
"Loved this place and would definitely stay here next time we go back."
United States
Eleni
The price is Rp3.378.306
Rp6.179.254 total
includes taxes & fees
21 Dec - 22 Dec
The Weldon Hotel
Stovall | Living area
Blind Tiger Portland – Carleton Street

Blind Tiger Portland – Carleton Street

Blind Tiger Portland – Carleton Street
3.5 star property
West End, 0.4 km from Maine Medical Center
9.6 out of 10, Exceptional, (120)
"Loved the place "
United States
Stephen
The price is Rp3.279.262
Rp3.574.396 total
includes taxes & fees
11 Jan - 12 Jan 2026
Blind Tiger Portland – Carleton Street
Baxter | Premium bedding, individually decorated, individually furnished
Blind Tiger Portland - Danforth Street.

Blind Tiger Portland - Danforth Street.

Blind Tiger Portland - Danforth Street.
3.5 star property
West End, 1.1 km from Maine Medical Center
9.6 out of 10, Exceptional, (167)
"The property is beautiful, the staff is kind, and the rooms are spacious and clean. It was great to have a safe place to park the car while having so many things to do within walking distance. Being able to grab a quick breakfast before heading out was great too! We loved our stay here!"
United States
Darby
The price is Rp3.429.076
Rp3.737.693 total
includes taxes & fees
13 Jan - 14 Jan 2026
Blind Tiger Portland - Danforth Street.
Exclusive Apartment, 2 Bedrooms | Dining room
The Docent’s Collection – Thompson Block

The Docent’s Collection – Thompson Block

The Docent’s Collection – Thompson Block
3.5 star property
Old Port, 1.9 km from Maine Medical Center
9.6 out of 10, Exceptional, (257)
"Excellent property and the staff was so wonderful, would definitely come back here!"
United States
ERIC
The price is Rp2.640.389
Rp2.878.093 total
includes taxes & fees
21 Dec - 22 Dec
The Docent’s Collection – Thompson Block
Bar (on property)
Canopy by Hilton Portland Waterfront

Canopy by Hilton Portland Waterfront

Canopy by Hilton Portland Waterfront
4.0 star property
Old Port, 1.5 km from Maine Medical Center
9.4 out of 10, Exceptional, (1005)
"Staff was lovely. Room was excellent and the hotel decor is very appealing. "
United States
Harris
The price is Rp2.033.808
Rp2.250.205 total
includes taxes & fees
22 Dec - 23 Dec
Canopy by Hilton Portland Waterfront
Terrace/patio
Portland Regency Hotel & Spa

Portland Regency Hotel & Spa

Portland Regency Hotel & Spa
3.5 star property
Old Port, 1.8 km from Maine Medical Center
9.4 out of 10, Exceptional, (1551)
"Yes, excellent service and we really enjoyed our stay."
United States
Bruce
Portland Regency Hotel & Spa
Royal Suite, 1 Bedroom | Frette Italian sheets, hypo-allergenic bedding, pillow-top beds
The Press Hotel, Marriott Autograph Collection

The Press Hotel, Marriott Autograph Collection

The Press Hotel, Marriott Autograph Collection
4.0 star property
Downtown Portland, 1.6 km from Maine Medical Center
9.4 out of 10, Exceptional, (1001)
"Beautiful hotel, good & convenient restaurant and very short walk to Merrill Auditorium"
United States
PETER
The price is Rp2.603.434
Rp2.880.440 total
includes taxes & fees
21 Dec - 22 Dec
The Press Hotel, Marriott Autograph Collection
Standard Room, 1 King Bed, Non Smoking | In-room safe, desk, laptop workspace, blackout curtains
Cambria Hotel Portland Downtown-Old Port

Cambria Hotel Portland Downtown-Old Port

Cambria Hotel Portland Downtown-Old Port
3.0 star property
East Bayside, 2.3 km from Maine Medical Center
9.4 out of 10, Exceptional, (1134)
"Super modern, super clean, super friendly staff, love Cambria hotels"
United States
Robert
The price is Rp1.651.283
Rp2.280.583 total
includes taxes & fees
4 Jan - 5 Jan 2026
Cambria Hotel Portland Downtown-Old Port
Exterior
Embassy Suites by Hilton Portland Maine

Embassy Suites by Hilton Portland Maine

Embassy Suites by Hilton Portland Maine
3.5 star property
2.9 km from Maine Medical Center
9.4 out of 10, Exceptional, (1132)
"Room was spotless and the staff was extremely friendly and knowledgeable! Would definitely stay here again!"
United States
Lori ann
The price is Rp1.598.016
Rp1.768.045 total
includes taxes & fees
21 Dec - 22 Dec
Embassy Suites by Hilton Portland Maine
Exterior
Courtyard Portland Downtown/Waterfront

Courtyard Portland Downtown/Waterfront

Courtyard Portland Downtown/Waterfront
3.0 star property
Old Port, 1.5 km from Maine Medical Center
9.2 out of 10, Wonderful, (1003)
"It was a nice stay for the night"
United States
Katy
The price is Rp1.714.538
Rp1.896.965 total
includes taxes & fees
4 Jan - 5 Jan 2026
Courtyard Portland Downtown/Waterfront
Premium bedding, desk, blackout curtains, iron/ironing board
Portland Harbor Hotel

Portland Harbor Hotel

Portland Harbor Hotel
4.0 star property
Old Port, 1.6 km from Maine Medical Center
9.2 out of 10, Wonderful, (1712)
"Beautiful room, friendly staff, and perfect location."
United States
Lisa
The price is Rp1.833.723
Rp2.663.877 total
includes taxes & fees
17 Dec - 18 Dec
Portland Harbor Hotel
Aerial view
Hilton Garden Inn Portland Downtown Waterfront

Hilton Garden Inn Portland Downtown Waterfront

Hilton Garden Inn Portland Downtown Waterfront
3.0 star property
Old Port, 2.1 km from Maine Medical Center
9.2 out of 10, Wonderful, (1007)
"Great staff and a surprisingly great free breakfast."
United States
Paul
The price is Rp1.584.699
Rp1.753.312 total
includes taxes & fees
21 Dec - 22 Dec
Hilton Garden Inn Portland Downtown Waterfront
Tapas bar
AC Hotel Portland Downtown/Waterfront, ME

AC Hotel Portland Downtown/Waterfront, ME

AC Hotel Portland Downtown/Waterfront, ME
3.5 star property
East Bayside, 2.3 km from Maine Medical Center
9.2 out of 10, Wonderful, (1003)
"The amenities and location "
United States
Michael
The price is Rp1.448.202
Rp1.602.291 total
includes taxes & fees
21 Dec - 22 Dec
AC Hotel Portland Downtown/Waterfront, ME
Exterior
La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

La Quinta Inn & Suites by Wyndham Portland DT/Maine Med
3.0 star property
0.6 km from Maine Medical Center
8.8 out of 10, Excellent, (2282)
"Great breakfast options and very convenient location."
United States
Greta
The price is Rp1.414.910
Rp1.565.556 total
includes taxes & fees
16 Dec - 17 Dec
La Quinta Inn & Suites by Wyndham Portland DT/Maine Med
Front of property – evening/night
Inn at St John Portland In-Town

Inn at St John Portland In-Town

Inn at St John Portland In-Town
2.5 star property
Valley Street, 0.3 km from Maine Medical Center
8.8 out of 10, Excellent, (1142)
"Friendly helpful staff and a nice independent location "
United States
Robert
The price is Rp1.331.680
Rp1.451.531 total
includes taxes & fees
16 Dec - 17 Dec
Inn at St John Portland In-Town
Lounge
Hyatt Place Portland Downtown - Old Port Square

Hyatt Place Portland Downtown - Old Port Square

Hyatt Place Portland Downtown - Old Port Square
3.0 star property
Old Port, 1.6 km from Maine Medical Center
9.0 out of 10, Wonderful, (1291)
"Room was great, awesome location!"
United States
Erick
The price is Rp1.614.662
Rp1.786.462 total
includes taxes & fees
5 Jan - 6 Jan 2026
Hyatt Place Portland Downtown - Old Port Square
Exterior
Holiday Inn Portland-By the Bay by IHG

Holiday Inn Portland-By the Bay by IHG

Holiday Inn Portland-By the Bay by IHG
4.0 star property
Portland Arts District, 1.2 km from Maine Medical Center
8.8 out of 10, Excellent, (1430)
"Every thing was perfect, service, accomodations, and friendly staff!!!"
United States
Michael
The price is Rp1.298.388
Rp1.436.536 total
includes taxes & fees
17 Dec - 18 Dec
Holiday Inn Portland-By the Bay by IHG
View from property
The Westin Portland Harborview

The Westin Portland Harborview

The Westin Portland Harborview
4.0 star property
Downtown Portland, 0.9 km from Maine Medical Center
8.8 out of 10, Excellent, (1002)
"Helpful and friendly staff"
United States
Wei Chien
The price is Rp1.631.308
Rp1.804.878 total
includes taxes & fees
4 Jan - 5 Jan 2026
The Westin Portland Harborview
Property entrance
Aloft Portland Downtown Waterfront ME

Aloft Portland Downtown Waterfront ME

Aloft Portland Downtown Waterfront ME
3.0 star property
Downtown Portland, 1.4 km from Maine Medical Center
8.8 out of 10, Excellent, (1004)
"Clean, good breakfast and nice bar! "
United States
James
The price is Rp1.315.034
Rp1.454.953 total
includes taxes & fees
18 Dec - 19 Dec
Aloft Portland Downtown Waterfront ME
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Maine Medical Center Hotel Reviews

Embassy Suites by Hilton Portland Maine

Embassy Suites by Hilton Portland Maine

10/10 Excellent
"Room was spotless and the staff was extremely friendly and knowledgeable! Would definitely stay here again!"
Lori ann 1-night trip
Posted 7 days ago
Embassy Suites by Hilton Portland Maine

Hotels near other Maine Medical Center attractions

State Street Church

Portland’s history of religious tolerance finds its place in a Gothic Revival building at the city center, perfect for attending religious services while on vacation.
See properties

Portland Exposition Building

Learn about the events happening in Portland Exposition Building during your trip to Portland. Experience the area's entertainment choices and acclaimed theatre scene.
See properties

Frequently asked questions

What's the area like around Maine Medical Center?
Maine Medical Center is located in a welcoming area of Portland known for its beautiful ocean views and sporting events. If you're looking for a convenient place to stay, take a look at the 191 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Maine Medical Center?
Adjacent to Maine Medical Center, Inn at St John Portland In-Town is one of the top choices for your stay based on our traveller data, and this B&B offers free breakfast and free parking. Other good choices close by include Portland Harbor Hotel and Clarion Hotel Portland Airport ME.
How many hotels should I expect to find close to Maine Medical Center?
Expedia has 191 hotels and other accommodation options within a mile from Maine Medical Center.
If I need to cancel the hotel reservation for my stay near Maine Medical Center, will I receive a refund?
Yes, you'll find most hotel room reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best options available near Maine Medical Center.
What can I see and do near Maine Medical Center?
International Cryptozoology Museum, Portland Museum of Art and Maine Narrow Gauge Railroad Company and Museum feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like State Theatre, Victoria Mansion and Portland Head Light. You can watch performances at Merrill Auditorium, Portland Stage and Port City Music Hall if you're interested in local theatre.

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