Find hotels in Mill Creek, IL from Rp1.075.609

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
25 Dec - 26 Dec
Tomorrow
26 Dec - 27 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Mill Creek hotels

Desk, free WiFi
Town House Inn Cape Giradreau

Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
2.5 star property
Cape Girardeau
6.0 out of 10, (206)
"Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors."
United States
Gary
The price is Rp920.755
Rp1.075.609 total
includes taxes & fees
6 Jan - 7 Jan 2026
Town House Inn Cape Giradreau
Standard Room, 1 Queen Bed, Non Smoking, Garden View | Free WiFi
Rockwood Inn

Rockwood Inn

Rockwood Inn
2.0 star property
Cape Girardeau
10.0 out of 10, Exceptional, (18)
"We came into town for a concert and had a blast! The hotel was super comfy, and the staff were friendly. The rooms were very clean and the decor was beautiful! "
United States
Vanessa
The price is Rp2.519.478
Rp2.842.324 total
includes taxes & fees
28 Dec - 29 Dec
Rockwood Inn
Business centre
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1000)
"Very friendly staff and great breakfast"
United States
Ray
The price is Rp1.506.523
Rp1.699.379 total
includes taxes & fees
6 Jan - 7 Jan 2026
Drury Inn & Suites Cape Girardeau
Exterior
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.2 out of 10, Very good, (885)
"Room was clean and spacious."
United States
George
The price is Rp1.171.870
Rp1.414.110 total
includes taxes & fees
25 Jan - 26 Jan 2026
Candlewood Suites Cape Girardeau by IHG
Courtyard
Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (785)
"Excellent stay"
United States
Christina
The price is Rp1.770.863
Rp1.997.781 total
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn Cape Girardeau I 55 East
Lobby
Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (142)
"Nice hotel, clean and comfortable "
United States
Laura
The price is Rp1.473.208
Rp1.661.985 total
includes taxes & fees
25 Jan - 26 Jan 2026
Fairfield Inn & Suites by Marriott Cape Girardeau
Free daily on-the-go breakfast
Hotel 7 Inn Anna

Hotel 7 Inn Anna

Hotel 7 Inn Anna
2.5 star property
Anna
6.6 out of 10, (217)
"The staff was wonderful"
United States
Donna
The price is Rp1.471.129
Rp1.706.342 total
includes taxes & fees
28 Dec - 29 Dec
Hotel 7 Inn Anna
Lobby
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1002)
"Nice place for a stay at a reasonable price."
United States
Arthur
The price is Rp1.173.382
Rp1.323.764 total
includes taxes & fees
30 Dec - 31 Dec
Pear Tree Inn Cape Girardeau Near the Medical Center
Lobby
Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.2 out of 10, Good, (686)
"Overall was wonderful customer service and breakfast"
United States
Stephanie
The price is Rp965.664
Rp1.089.404 total
includes taxes & fees
1 Jan - 2 Jan 2026
Quality Inn Cape Girardeau North
Lobby sitting area
The Riverview

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (477)
"The room was clean and the mattress was extremely comfortable "
United States
Stacy
The price is Rp1.614.469
Rp1.821.348 total
includes taxes & fees
28 Dec - 29 Dec
The Riverview
Lobby
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (468)
"The staff was very helpful and friendly. The rooms were modern and clean. The downtown location was perfect for us. "
United States
Deborah
The price is Rp2.095.625
Rp2.374.637 total
includes taxes & fees
4 Jan - 5 Jan 2026
Courtyard by Marriott Cape Girardeau Downtown
Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1001)
"Great place and staff, very accommodating!"
United States
Megan
The price is Rp1.506.523
Rp1.699.379 total
includes taxes & fees
6 Jan - 7 Jan 2026
Drury Plaza Hotel Cape Girardeau Conference Center
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1000)
"We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly. "
United States
Brian
The price is Rp1.523.431
Rp1.718.645 total
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Lobby
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1001)
"Great stay"
United States
Heather
The price is Rp1.171.703
Rp1.321.869 total
includes taxes & fees
31 Dec - 1 Jan 2026
Pear Tree Inn Cape Girardeau West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Mill Creek Hotel Reviews

Makanda Inn

Makanda Inn

10/10 Excellent
"Peaceful and relaxing. "
Amy Cristine 1-night trip
Posted 8 months ago
Makanda Inn

More cheap stays in Mill Creek

Quality Inn

Quality Inn

2011 North Kingshighway Cape Girardeau MO
The price is Rp965.664 per night from 1 Jan to 2 Jan
Rp965.664
Rp1.089.404 total
1 Jan - 2 Jan 2026
includes taxes & fees
7/10 Good! (686 reviews)

Frequently asked questions

Where is the best place to stay in Mill Creek?
Drury Plaza Hotel Cape Girardeau Conference Center, located 18.1 mi (29.2 km) from the heart of Mill Creek, is a top choice for your stay, based on our traveller data. Other good options for your visit to the area are The Riverview and Courtyard by Marriott Cape Girardeau Downtown. See all available top hotels, or vacation rentals in Mill Creek.
If I need to cancel my hotel reservation in Mill Creek, will I receive a refund?
Yes! You'll find that most hotel reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of check in. If your reservation is non-refundable, you might be able to cancel it and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Mill Creek.
What's it like to stay in Mill Creek?
Those travelling to Mill Creek will definitely enjoy the sights to see and things to do. There are 155 hotels and other accommodation options in the surrounding area. Find out more about Mill Creek.
What should I do while I'm visiting Mill Creek?
Places to visit in the wider area include Trail of Tears State Park, Isle Casino Cape Girardeau and Hunter Valley Winery. You'll also find Show Me Center and Dongola Lake in the area. Take a look at what more there is to see and do in Expedia's Mill Creek guide.
What's the weather like in Mill Creek?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 4°C. Average annual precipitation for Mill Creek is 1431 mm.