A calm river with clear water, surrounded by dense trees and rocky banks.

Find hotels in O Brien, FL from Rp1.160.851

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Our top choices for O Brien hotels

Days Inn by Wyndham Lake City I-10

Days Inn by Wyndham Lake City I-10
2.0 star property
Lake City
7.0 out of 10, Good, (1,003 reviews)
"Nice and restful place to stay"
United States
Frederick
The price is Rp1.060.982
Rp1.193.605 total
includes taxes & fees
1 Jul - 2 Jul
Days Inn by Wyndham Lake City I-10

Best Western Plus Lake City

Best Western Plus Lake City
2.5 star property
Lake City
9.0 out of 10, Wonderful, (1,061 reviews)
"The location was great have many restaurants around, and the staff was very friendly"
United States
Carla
The price is Rp1.560.177
Rp1.755.199 total
includes taxes & fees
1 Jul - 2 Jul
Best Western Plus Lake City

Baymont by Wyndham Lake City I-75

Baymont by Wyndham Lake City I-75
2.5 star property
Lake City
5.0 out of 10, (1,006 reviews)
"Desk & housekeeping staff were super helpful & friendly!"
United States
Cameron
The price is Rp1.031.788
Rp1.160.851 total
includes taxes & fees
5 Jul - 6 Jul
Baymont by Wyndham Lake City I-75

Tru by Hilton Lake City

Tru by Hilton Lake City
2.5 star property
Lake City
9.2 out of 10, Wonderful, (1,005 reviews)
"Clean helpful staff and breakfast was good.parking good also"
United States
John
The price is Rp1.953.498
Rp2.197.775 total
includes taxes & fees
5 Jul - 6 Jul
Tru by Hilton Lake City

Quality Inn & Suites Live Oak I-10 Exit 283

Quality Inn & Suites Live Oak I-10 Exit 283
2.5 star property
Live Oak
7.2 out of 10, Good, (573 reviews)
"Staff was awesome. Friendly and helpful. Room was clean and quiet."
United States
Patricia
The price is Rp1.384.654
Rp1.523.120 total
includes taxes & fees
13 Jul - 14 Jul
Quality Inn & Suites Live Oak I-10 Exit 283

La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City
3.0 star property
Lake City
8.6 out of 10, Excellent, (1,133 reviews)
"Enjoyed our stay"
United States
Tammie
The price is Rp1.686.919
Rp1.897.784 total
includes taxes & fees
5 Jul - 6 Jul
La Quinta Inn & Suite by Wyndham Lake City

Regal Inn

Regal Inn
2.5 star property
Lake City
8.4 out of 10, Very good, (605 reviews)
"Surprisingly well maintained and clean for the price. Lady at the front desk was kind and sweet."
United States
Johnny
The price is Rp1.107.476
Rp1.245.821 total
includes taxes & fees
6 Jul - 7 Jul
Regal Inn

Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee
2.5 star property
White Springs
7.2 out of 10, Good, (677 reviews)
"Was great!! Clean rooms and peaceful.. Would stay here again and again.."
United States
Anthony
The price is Rp1.157.582
Rp1.273.341 total
includes taxes & fees
20 Jul - 21 Jul
Quality Inn White Springs Suwanee

Palms Garden Inn

Palms Garden Inn
2.0 star property
Lake City
7.6 out of 10, Good, (627 reviews)
"REALLY NICE PLACE, VERY CLEAN, WONDERFUL STAFF"
United States
Caroline
The price is Rp1.159.422
Rp1.304.350 total
includes taxes & fees
7 Jul - 8 Jul
Palms Garden Inn

Comfort Suites Lake City

Comfort Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,006 reviews)
"Great stay - easy - accommodating - quiet!"
United States
Paula
The price is Rp1.878.942
Rp2.113.810 total
includes taxes & fees
12 Jul - 13 Jul
Comfort Suites Lake City

Days Inn by Wyndham Lake City I-75

Days Inn by Wyndham Lake City I-75
2.0 star property
Lake City
7.6 out of 10, Good, (1,005 reviews)
"Great for a short stay and clean"
United States
Brizheet
The price is Rp1.132.670
Rp1.274.254 total
includes taxes & fees
1 Jul - 2 Jul
Days Inn by Wyndham Lake City I-75

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
Alachua
9.4 out of 10, Exceptional, (1,007 reviews)
"The staff were amazing, great location, big rooms, great breakfast"
United States
Brittani
The price is Rp1.863.888
Rp2.096.874 total
includes taxes & fees
12 Jul - 13 Jul
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Super 8 by Wyndham Lake City

Super 8 by Wyndham Lake City
2.0 star property
Lake City
7.4 out of 10, Good, (734 reviews)
"The room was clean, staff were very nice and the breakfast was outstanding."
United States
Michelle
The price is Rp1.168.348
Rp1.314.391 total
includes taxes & fees
29 Jul - 30 Jul
Super 8 by Wyndham Lake City

Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,000 reviews)
"Breakfast menu was fresh, the room was clean, and the staff friendly and professional."
United States
Claire
The price is Rp2.035.014
Rp2.289.390 total
includes taxes & fees
5 Jul - 6 Jul
Hampton Inn & Suites Lake City

Quality Inn Lake City

Quality Inn Lake City
2.5 star property
Lake City
8.0 out of 10, Very good, (1,004 reviews)
"It was clean and comfortable bed !"
United States
Glenda
The price is Rp1.269.206
Rp1.427.857 total
includes taxes & fees
7 Jul - 8 Jul
Quality Inn Lake City

Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
Alachua
9.4 out of 10, Exceptional, (527 reviews)
"Wonderful place to stay"
United States
Tamela
The price is Rp1.888.279
Rp2.124.314 total
includes taxes & fees
14 Jul - 15 Jul
Hampton Inn & Suites Alachua I-75

Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center
2.0 star property
Lake City
7.6 out of 10, Good, (200 reviews)
"Clean room hot water nice upgrades and friendly staff"
United States
Pennee
The price is Rp1.160.315
Rp1.305.354 total
includes taxes & fees
1 Jul - 2 Jul
Motel 6 – Lake City, Fl – Medical Center

The Blanche

The Blanche
2.0 star property
Lake City
9.4 out of 10, Exceptional, (194 reviews)
"Great property! Beautiful renovated!"
United States
Brandi
The price is Rp2.650.873
Rp2.982.233 total
includes taxes & fees
1 Jul - 2 Jul
The Blanche

Royal Inn

Royal Inn
2.0 star property
Live Oak
6.2 out of 10, (60 reviews)
"Price and owners are friendly"
United States
rita
The price is Rp1.124.613
Rp1.237.074 total
includes taxes & fees
6 Jul - 7 Jul
Royal Inn

Econo Lodge Live Oak

Econo Lodge Live Oak
2.0 star property
Live Oak
7.0 out of 10, Good, (312 reviews)
"The room was fairly cheap and staff was friendly."
United States
James
The price is Rp1.395.948
Rp1.535.543 total
includes taxes & fees
29 Jul - 30 Jul
Econo Lodge Live Oak
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

A calm river surrounded by trees reflecting in the water.

Top O Brien Hotel Reviews

More cheap stays in O Brien

Frequently asked questions

Where is the best place to stay in O Brien?
La Quinta Inn & Suite by Wyndham Lake City, located 18.2 mi (29.3 km) from the heart of O Brien, is a top choice for your stay, based on our traveller data. Two other options for your trip to the area are Holiday Inn Express & Suites Alachua - Gainesville Area by IHG and Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy. See all available top hotels, or vacation rentals in O Brien.
If I need to cancel my hotel reservation in O Brien, will I receive a refund?
Yes! You'll find that most hotel bookings are refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.
What are some accommodation options with pools in O Brien?
La Quinta Inn & Suite by Wyndham Lake City: Features on-the-go, an indoor pool and free self parking. Holiday Inn Express & Suites Alachua - Gainesville Area by IHG and Tru by Hilton Lake City are two additional hotels that feature an on-site pool. View all hotels with pools in O Brien.
How is it to stay in O Brien?
Visitors to O Brien will definitely find plenty to explore and enjoy. In O Brien, there are 10 hotels and other accommodation options to choose from. Find out more about O Brien.
What are the top places to visit in O Brien?
Natural beauty is on display at Suwannee River, Ichetucknee River and Ichetucknee Springs State Park. You'll also find Wes Skiles Peacock Springs State Park and First Federal Sportsplex in the area. Take a look at what more there is to see and do in Expedia's O Brien guide.
What's the seasonal weather in O Brien?
The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 14°C. Average annual precipitation for O Brien is 1278 mm.

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