Search Hotels in Otay Mesa West, San Diego

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Our top choices for Otay Mesa West hotels

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
19.2 km from Otay Mesa West
8.4 out of 10, Very good, (5,992 reviews)
"Perfect location for cruise"
United States
blasimar
The price is Rp2.279.305
Rp3.229.643 total
includes taxes & fees
18 Jan - 19 Jan
Wyndham San Diego Bayside

The Bristol Hotel San Diego

The Bristol Hotel San Diego
3.5 star property
18.5 km from Otay Mesa West
8.6 out of 10, Excellent, (1,468 reviews)
"Clean room, staff was pleasant "
United States
Miguel
The Bristol Hotel San Diego

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay, 26.8 km from Otay Mesa West
8.4 out of 10, Very good, (1,335 reviews)
"Great place for our family getaway! Loved the S’mores on the beach! "
United States
Dani
The price is Rp2.565.167
Rp3.840.329 total
includes taxes & fees
2 Feb - 3 Feb
San Diego Mission Bay Resort

Paradise Point Resort & Spa

Paradise Point Resort & Spa
4.0 star property
Mission Bay, 27.9 km from Otay Mesa West
8.6 out of 10, Excellent, (2,363 reviews)
"Great facility and amenities. We look forward to taking our family back again. "
United States
Andy
The price is Rp1.736.643
Rp2.889.316 total
includes taxes & fees
19 Jan - 20 Jan
Paradise Point Resort & Spa

Loews Coronado Bay Resort

Loews Coronado Bay Resort
4.0 star property
9.7 km from Otay Mesa West
8.8 out of 10, Excellent, (1,060 reviews)
"Clean room, gorgeous grounds, very friendly staff "
United States
Taryn
The price is Rp3.187.485
Rp4.359.097 total
includes taxes & fees
8 Feb - 9 Feb
Loews Coronado Bay Resort

Westgate Hotel

Westgate Hotel
4.5 star property
18.5 km from Otay Mesa West
9.0 out of 10, Wonderful, (1,001 reviews)
"The hotel was a great stay. Beautiful lobby, large room and such a comfortable bed."
United States
Victor
Westgate Hotel

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
31.2 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,668 reviews)
"Very clean resort. "
United States
Petrina
Sycuan Casino Resort

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Gaslamp Quarter, 17.5 km from Otay Mesa West
9.0 out of 10, Wonderful, (3,221 reviews)
"Great view easy checking in fun atmosphere and good food "
United States
Sergio
The price is Rp4.602.358
Rp6.147.616 total
includes taxes & fees
16 Jan - 17 Jan
Hard Rock Hotel San Diego

The Dana on Mission Bay

The Dana on Mission Bay
3.5 star property
Mission Bay, 27.1 km from Otay Mesa West
9.0 out of 10, Wonderful, (3,987 reviews)
"We had a wonderful stay!"
United States
Megan
The price is Rp2.644.453
Rp3.427.668 total
includes taxes & fees
19 Jan - 20 Jan
The Dana on Mission Bay

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
19.1 km from Otay Mesa West
9.0 out of 10, Wonderful, (905 reviews)
"Great stay. Would definitely stay again."
United States
Zoraima
The price is Rp1.863.221
Rp2.160.311 total
includes taxes & fees
22 Jan - 23 Jan
The DEXTRO Little Italy, BW Premier Collection

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
Marina District, 18.2 km from Otay Mesa West
9.0 out of 10, Wonderful, (2,880 reviews)
"Excellent stay...wonderful staff"
United States
Michelle
The price is Rp3.358.523
Rp4.813.658 total
includes taxes & fees
22 Jan - 23 Jan
Manchester Grand Hyatt San Diego

Humphreys Half Moon Inn

Humphreys Half Moon Inn
3.5 star property
22.3 km from Otay Mesa West
9.2 out of 10, Wonderful, (2,736 reviews)
"Great stay, highly recommend."
United States
Ryan
The price is Rp2.597.210
Rp3.322.742 total
includes taxes & fees
2 Feb - 3 Feb
Humphreys Half Moon Inn

GreenTree Inn San Diego Mission Bay

GreenTree Inn San Diego Mission Bay
2.5 star property
Pacific Beach, 29.3 km from Otay Mesa West
8.0 out of 10, Very good, (1,901 reviews)
"The staff was very nice and great location"
United States
Curtis
The price is Rp1.232.191
Rp1.416.341 total
includes taxes & fees
25 Jan - 26 Jan
GreenTree Inn San Diego Mission Bay

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
3.0 star property
Gaslamp Quarter, 17.6 km from Otay Mesa West
9.0 out of 10, Wonderful, (1,244 reviews)
"Friendly staff, great location, excellent value overall "
United States
Maryann
The price is Rp2.684.908
Rp3.113.016 total
includes taxes & fees
18 Jan - 19 Jan
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley
2.5 star property
23.5 km from Otay Mesa West
8.6 out of 10, Excellent, (1,363 reviews)
"Great breakfast-comfortable rooms-helpful staff-great location for events"
United States
bill
The price is Rp1.624.100
Rp1.866.822 total
includes taxes & fees
25 Jan - 26 Jan
Hampton Inn San Diego/Mission Valley

Embassy Suites by Hilton San Diego Bay Downtown

Embassy Suites by Hilton San Diego Bay Downtown
4.0 star property
Marina District, 18.4 km from Otay Mesa West
9.0 out of 10, Wonderful, (1,579 reviews)
"Very easy vacation, convenient breakfast as well as location."
United States
Kathy
The price is Rp3.180.739
Rp4.299.771 total
includes taxes & fees
30 Jan - 31 Jan
Embassy Suites by Hilton San Diego Bay Downtown

The Sofia Hotel

The Sofia Hotel
3.5 star property
18.5 km from Otay Mesa West
8.6 out of 10, Excellent, (1,686 reviews)
"Great location and history to the hotel "
United States
Stephanie
The Sofia Hotel

Best Western Seven Seas

Best Western Seven Seas
3.0 star property
22.9 km from Otay Mesa West
8.0 out of 10, Very good, (3,124 reviews)
"Breakfast was good and the staff was friendly and excellent. "
United States
Thuan
The price is Rp1.183.923
Rp1.360.861 total
includes taxes & fees
20 Jan - 21 Jan
Best Western Seven Seas

Fairfield Inn & Suites by Marriott San Diego Pacific Beach

Fairfield Inn & Suites by Marriott San Diego Pacific Beach
2.5 star property
Pacific Beach, 29 km from Otay Mesa West
8.8 out of 10, Excellent, (832 reviews)
"Great stay!"
United States
Cynthia
The price is Rp1.534.715
Rp1.764.079 total
includes taxes & fees
25 Jan - 26 Jan
Fairfield Inn & Suites by Marriott San Diego Pacific Beach

Margaritaville Hotel San Diego Gaslamp Quarter

Margaritaville Hotel San Diego Gaslamp Quarter
4.0 star property
Gaslamp Quarter, 17.6 km from Otay Mesa West
9.0 out of 10, Wonderful, (1,198 reviews)
"Perfect location in the Gaslamp District. Rooms were large & clean with friendly staff. "
United States
Ginger
The price is Rp3.172.306
Rp4.362.512 total
includes taxes & fees
20 Jan - 21 Jan
Margaritaville Hotel San Diego Gaslamp Quarter
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa West

Find the best Otay Mesa West areas for the activities you enjoy most. Learn more about Otay Mesa West
Learn more about Otay Mesa West

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Gaslamp Quarter

San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Dog Beach and Ocean Beach Farmers Market.

Top Otay Mesa West Hotel Reviews

Frequently asked questions

What is Otay Mesa West like?
Otay Mesa West is a neighbourhood that travellers like for its cathedral.
If I need to cancel my hotel reservation in Otay Mesa West, will I receive a refund?
Yes! The majority of room reservations are refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to review top deals in Otay Mesa West.
What is there to do around this San Diego neighbourhood?
A few places to visit in the area around Otay Mesa West include San Ysidro Border Crossing, Las Americas Premium Outlets and Sesame Place San Diego. While you're out sightseeing in San Diego, make sure that you visit other sights such as Tijuana Customs - Garita El Chaparral or North Island Credit Union Amphitheatre.
How can I get around Otay Mesa West and the greater San Diego area?
Ready to get out and explore the city? Iris Avenue Trolley Station is the closest metro station.