The Best Hotels Closest to South Texas Medical Center in San Antonio - 2026 Updated Prices

A modern medical building with reflective glass windows and a clear sky.

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Our top choices for South Texas Medical Center hotels

A spacious lobby with multiple seating areas, a central coffee table, and a view of the upper floors.

A modern lobby with a grey sofa, blue armchairs, and a stone accent wall.

A hotel room with two beds, a TV, a desk with a lamp, and a dresser.

An indoor swimming pool with multiple lanes, safety signs, and a view of the outside through large windows.

1. Drury Inn & Suites San Antonio Northwest Medical Center

Medical Center District, 2.9 km from South Texas Medical Center

Melissa

Rp1.595.073

Rp1.885.521 total

includes taxes & fees

2 Sept - 3 Sept

A modern living room with a fireplace, a flat-screen TV, and a stone accent wall.

A reception area with a wooden reception desk, a 'Corner Market' sign, and a refrigerator stocked with beverages.

A modern cafe with wooden furniture, white tables, and a brick wall.

A swimming pool with a wooden ceiling, lounge chairs, and a view of trees and a building.

2. Fairfield Inn & Suites by Marriott San Antonio Medical Center

Medical Center District, 1 km from South Texas Medical Center

Matthew

Rp1.532.858

Rp1.789.612 total

includes taxes & fees

6 Sept - 7 Sept

A modern bar area with wooden bar counters, black bar stools, and pendant lighting.

A hotel room with a large bed, a desk, and a chair.

A modern hotel lobby with a mix of seating arrangements, including round tables and sofas, and a bar area with a high counter.

A courtyard with outdoor seating, a fire pit, and a covered area.

3. Courtyard by Marriott Medical Center San Antonio

Medical Center District, 1.3 km from South Texas Medical Center

Elizabeth

Rp1.577.525

Rp1.864.776 total

includes taxes & fees

4 Sept - 5 Sept

A hotel dining area with multiple tables and chairs, a counter with a coffee machine, and a view of the outside through large windows.

A hotel with a red-roofed entrance, multiple floors, and a visible flag.

A gym with multiple cardio machines, including treadmills and elliptical trainers, arranged in a spacious room with a carpeted floor and neutral-colored walls.

A hotel room with a large bed, a desk with a television, a chair, and a nightstand with a lamp.

4. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

Medical Center District, 2.4 km from South Texas Medical Center

Melissa

Rp1.573.802

Rp1.860.377 total

includes taxes & fees

8 Sept - 9 Sept

A hotel pool area with lounge chairs and a building with large windows in the background.

A large banquet hall with round tables, chairs, and chandeliers.

A hotel lobby with a seating area, a large potted plant, a decorative wall, and a vintage car display.

5. The Westin San Antonio North

3.2 km from South Texas Medical Center

Evert

Rp1.581.956

Rp1.897.311 total

includes taxes & fees

30 Aug - 31 Aug

A modern kitchen with a large window, wooden counter, and two bar stools.

A compact kitchenette with a built-in microwave, a black refrigerator, and a wooden countertop.

A hotel room with two beds, a bedside table with a phone, a window with curtains, and a wooden floor.

A Park Inn hotel with a brick facade, multiple parking spaces, and a clear sky.

6. Park Inn by Radisson, Medical Center

Medical Center District, 1 km from South Texas Medical Center

Amanda

Rp1.116.675

Rp1.303.718 total

includes taxes & fees

7 Sept - 8 Sept

A hotel room with two beds, a desk, a chair, a mirror, and a bathroom.

A laundry facility with multiple washing machines, a drying rack, and instructional posters on the wall.

A stone facade with a 'welcome' sign, a blue door, and a parking sign.

A compact kitchen with a built-in refrigerator, microwave, and coffee maker.

7. Studio 6 San Antonio, Tx - Northwest Medical Center

Medical Center District, 2.7 km from South Texas Medical Center

Ruben

Rp831.480

Rp970.621 total

includes taxes & fees

30 Aug - 31 Aug

A building entrance with a glass door, a Pepsi vending machine, and a yellow bollard.

A hotel with a prominent 'OYO INN & SUITES' sign, featuring a two-story structure with balconies and a covered entrance.

A room with a table and chairs, a clock, and framed pictures on the wall.

A hotel reception area with a glass door entrance, a reception desk, and a wall-mounted sign for the OYO hotel.

8. OYO Inn & Suites Medical Center San Antonio

Medical Center District, 3.1 km from South Texas Medical Center

Ronnie

Rp899.544

Rp1.140.427 total

includes taxes & fees

10 Sept - 11 Sept

A gas station with a sign for 'Atria Inn & Suites' and a 'Clearance - 12' sign.

A hotel room with a sofa, a desk, a chair, a bed, and a mirror.

A modern bathroom with a white sink, large mirror, and towel rack.

A hotel room with a bed, two bedside tables with lamps, a desk with a telephone, a mirror, and a door leading to another room.

9. Atria Inn & Suites

Medical Center District, 2.2 km from South Texas Medical Center

José

Rp1.078.211

Rp1.258.811 total

includes taxes & fees

28 Aug - 29 Aug

A reception area with a glass door entrance, a reception desk, and a wall-mounted fire extinguisher.

A small, modern room with a wooden dining table, a mirror, a TV, and a small kitchenette.

A hotel room with a bed, bedside table, desk, chair, TV, and a wardrobe.

A small, modern room with two brown leather sofas, a black cabinet, and a window with blinds.

10. Motel 6 San Antonio, TX - Fiesta Trails

2.9 km from South Texas Medical Center

Alexis

Rp765.543

Rp893.872 total

includes taxes & fees

28 Aug - 29 Aug

A hotel room with a large bed, a desk with a chair, a television on a stand, and a mirror on the wall.

A hotel room with two beds, a wooden desk, and a chair.

A bathroom with a granite countertop sink, a mirror, a shower with a glass door, and a toilet.

A building with a red roof and a sign reading "Flex Studios."

11. Flex Studios

Medical Center District, 2.7 km from South Texas Medical Center

Jasper

Rp701.910

Rp829.720 total

includes taxes & fees

30 Aug - 31 Aug

A modern bedroom with a large bed, bedside tables, a desk, and a chair.

A swimming pool with a stone wall and a 'No Diving' sign, surrounded by a fence and a building with a stone facade.

A hotel reception area with a large number '6' sign, a poster advertising direct booking, and a view of the outside through a window.

A building with a stone facade, a prominent '6' sign, and a parking lot with marked handicapped spaces.

12. Motel 6 San Antonio, TX - Northwest Medical Center

Medical Center District, 2.8 km from South Texas Medical Center

Rachel

Rp824.567

Rp1.045.598 total

includes taxes & fees

29 Aug - 30 Aug

An indoor swimming pool with a hot tub, tiled flooring, and a seating area with tables and chairs.

An outdoor patio area with multiple tables and chairs, covered by a pergola structure.

A multi-story hotel with a central atrium, a parking lot, and surrounding greenery.

A hotel lobby with a curved reception desk, a seating area with a sofa and chairs, and a hallway leading to other rooms.

13. Drury Inn & Suites Near La Cantera Parkway

La Cantera District, 9 km from South Texas Medical Center

Samantha

Rp1.665.785

Rp1.969.109 total

includes taxes & fees

31 Aug - 1 Sept

A Holiday Inn Express reception desk with a modern design, featuring a large illuminated sign, a reception area, and a potted plant.

A poolside area with lounge chairs and a metal railing.

A swimming pool with lounge chairs and a covered seating area, surrounded by a building with large windows and a brick facade.

14. Holiday Inn Express San Antonio-Airport by IHG

9.2 km from South Texas Medical Center

Xiloneen

Rp1.737.050

Rp2.053.349 total

includes taxes & fees

27 Sept - 28 Sept

A covered outdoor seating area with lounge chairs and umbrellas, a pool in the background, and potted plants.

A modern office space with two desks, chairs, and a large window.

A spacious living area with a large sectional sofa, multiple coffee tables, and a wooden partition.

A bar area with a granite countertop, multiple bar stools, and hanging pendant lights.

15. Embassy Suites by Hilton San Antonio Landmark

La Cantera District, 8.7 km from South Texas Medical Center

Sylvia

Rp2.892.366

Rp3.419.036 total

includes taxes & fees

20 Sept - 21 Sept

A modern lobby with seating areas, a stone accent wall, and a wooden ceiling.

An outdoor patio with a pergola, pool, and outdoor seating area.

A reception desk with a computer, framed pictures on the wall, and pendant lighting.

A hotel entrance with a covered walkway, brick facade, and a sign indicating it is a Heritage Inn & Suites.

16. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Uptown, 9.5 km from South Texas Medical Center

Victor M.

Rp1.417.823

Rp1.676.076 total

includes taxes & fees

30 Aug - 31 Aug

A modern kitchen with a large flat-screen TV, a glass display case with wine glasses, and a breakfast buffet sign.

An outdoor patio area with a barbecue grill, seating arrangements, and potted plants.

A modern kitchen with a large island, bar stools, and a television displaying a football game.

A rectangular swimming pool with a clear blue water, surrounded by a black metal fence. There are lounge chairs and umbrellas on the poolside.

17. Staybridge Suites San Antonio Lackland AFB Area by IHG

Far West Side, 9.8 km from South Texas Medical Center

Denise

Rp2.534.675

Rp2.959.189 total

includes taxes & fees

20 Sept - 21 Sept

A multi-level hotel atrium with a central courtyard, outdoor seating, and a pool.

A lobby with a fountain, seating area, and a reception desk.

A spacious bar area with a long counter, multiple stools, and a television screen.

A building with a large arched doorway, a balcony with a railing, and a tree with green foliage in the foreground.

18. Estancia del Norte San Antonio, Tapestry Collection by Hilton

8.7 km from South Texas Medical Center

Kaybby

Rp2.456.331

Rp2.903.605 total

includes taxes & fees

2 Sept - 3 Sept

A modern hotel with a prominent sign reading "LA QUINTA".

A reception area with wooden reception desks, a cityscape mural, and a modern chandelier.

A modern lounge area with wooden and colorful seating, a round table, and a flat-screen TV on the wall.

A modern kitchen with a large window, a counter with various appliances, and a view of the parking lot.

19. La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

9.1 km from South Texas Medical Center

Ruben

Rp1.754.775

Rp2.048.700 total

includes taxes & fees

30 Aug - 31 Aug

A modern building with a distinctive roof structure and a large illuminated sign.

A modern lounge area with a pool table, seating, and a colorful rug.

A modern lounge area with sofas, chairs, and round tables, featuring a large window with a city view.

A modern hotel room with a large bed, a desk, and a mirror.

20. Aloft by Marriott San Antonio UTSA Area

Northwest Side, 7.3 km from South Texas Medical Center

Mark

Rp1.729.606

Rp2.044.549 total

includes taxes & fees

1 Sept - 2 Sept

View all properties

Compare popular hotels close to South Texas Medical Center

Property	Property class	Guest rating
Drury Inn & Suites San Antonio Northwest Medical Center	9.2 Wonderful 1,427 reviews	View
Fairfield Inn & Suites by Marriott San Antonio Medical Center	9.0 Wonderful 1,056 reviews	View
Courtyard by Marriott Medical Center San Antonio	8.8 Excellent 1,003 reviews	View
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW	8.4 Very good 3,598 reviews	View
The Westin San Antonio North	8.4 Very good 1,586 reviews	View

Top South Texas Medical Center Hotel Reviews

Courtyard by Marriott Medical Center San Antonio

10/10 Excellent

"Excellent hotel and stay. The breakfast is really good and the staff is always incredible. Never disappoints!"

Studio 6 Extended Stay - San Antonio, TX - Medical Center

10/10 Excellent

"Good enough"

Fairfield Inn & Suites by Marriott San Antonio Medical Center

10/10 Excellent

"Perfect stay, convenient to everything"

Atria Inn & Suites

10/10 Excellent

"Amazing comfortable and affordable"

Motel 6 San Antonio, TX - Fiesta Trails

10/10 Excellent

"Always well taken care of here . Great customer service especially when Kevin is there also new employee Nasha big help"

SpringHill Suites by Marriott San Antonio Medical Center/NW

10/10 Excellent

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Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG

10/10 Excellent

"Very nice place, we felt very safe and the staff is very accommodating and nice!"

Flex Studios

10/10 Excellent

"Four outa Four Jalapenos 👍✔️"

OYO Inn & Suites Medical Center San Antonio

8/10 Good

"Clean room, thank you"

Frequently asked questions

What's the area like around South Texas Medical Center?

South Texas Medical Center is located in a walkable area of San Antonio known for its stunning river views and cycling. If you're looking for a convenient place to stay, take a look at the 34 hotels and other accommodation options you'll find within a mile.

What's the best hotel to stay close to South Texas Medical Center?

Courtyard by Marriott Medical Center San Antonio is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. It's located just a short 0.8 mi (1.3 km) from South Texas Medical Center. Other good options close by include Fairfield Inn & Suites by Marriott San Antonio Medical Center and Park Inn by Radisson, Medical Center.

How many hotels should I expect to find close to South Texas Medical Center?

Expedia has 34 hotels and other accommodation options within a mile from South Texas Medical Center.

If I need to cancel the hotel reservation for my stay near South Texas Medical Center, will I receive a refund?

Yes, you'll find most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best deals near South Texas Medical Center.

What can I see and do near South Texas Medical Center?

You can watch performances at Woodlawn Theater, Sheldon Vexler Theatre and Laugh Out Loud Comedy Club if you're interested in local theatre. Create some family memories at Crystal Ice Palace and Monster Mini Golf. Looking for a little shopping break? A trip to Wonderland of the Americas Mall, Huebner Oaks and Ingram Park Mall might be just the ticket while you're in the area around South Texas Medical Center.

Search Hotels Near South Texas Medical Center, San Antonio

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Our top choices for South Texas Medical Center hotels

1. Drury Inn & Suites San Antonio Northwest Medical Center

2. Fairfield Inn & Suites by Marriott San Antonio Medical Center

3. Courtyard by Marriott Medical Center San Antonio

4. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

5. The Westin San Antonio North

6. Park Inn by Radisson, Medical Center

7. Studio 6 San Antonio, Tx - Northwest Medical Center

8. OYO Inn & Suites Medical Center San Antonio

9. Atria Inn & Suites

10. Motel 6 San Antonio, TX - Fiesta Trails

11. Flex Studios

12. Motel 6 San Antonio, TX - Northwest Medical Center

13. Drury Inn & Suites Near La Cantera Parkway

14. Holiday Inn Express San Antonio-Airport by IHG

15. Embassy Suites by Hilton San Antonio Landmark

16. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

17. Staybridge Suites San Antonio Lackland AFB Area by IHG

18. Estancia del Norte San Antonio, Tapestry Collection by Hilton

19. La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

20. Aloft by Marriott San Antonio UTSA Area

Compare popular hotels close to South Texas Medical Center

Top South Texas Medical Center Hotel Reviews

Courtyard by Marriott Medical Center San Antonio

Studio 6 Extended Stay - San Antonio, TX - Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center

Atria Inn & Suites

Motel 6 San Antonio, TX - Fiesta Trails

SpringHill Suites by Marriott San Antonio Medical Center/NW

Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG

Flex Studios

OYO Inn & Suites Medical Center San Antonio

Frequently asked questions