The Best Hotels Closest to Mayo Clinic Hospital - Saint Marys Campus in Rochester - 2026 Updated Prices

An aerial view of a campus with multiple buildings, parking lots, and surrounding greenery.

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Our top choices for Mayo Clinic Hospital - Saint Marys Campus hotels

A swimming pool with clear blue water, surrounded by lounge chairs and a view of residential buildings through large windows.

A modern lounge area with seating, a fireplace, and a bar area.

A modern reception area with a brick-patterned wall, two reception desks, a flat-screen TV, and seating arrangements including a sofa and chairs.

An outdoor patio area with wicker furniture, a central fire feature, and a stone building in the background.

1. Residence Inn by Marriott Rochester Mayo Clinic Area South

2.3 km from Mayo Clinic Hospital - Saint Marys Campus

Chee

Rp2.470.614

Rp2.844.295 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor patio area with a concrete floor, wooden fence, and string lights.

A breakfast bar with a wooden counter, a coffee machine, and a refrigerator.

A modern living room with a stone fireplace, a blue armchair, a round coffee table, and a large window offering a view of the outdoors.

2. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Kutzky Park, 0.9 km from Mayo Clinic Hospital - Saint Marys Campus

Jon

Rp2.239.290

Rp2.577.983 total

includes taxes & fees

23 Oct - 24 Oct

An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.

An indoor swimming pool with wooden ceiling beams, yellow chairs, and tables along the sides.

A modern lounge area with a sofa, chairs, and tables.

A modern hotel room with a bed, desk, and kitchenette.

3. Home2 Suites by Hilton Rochester Mayo Clinic Area

2.3 km from Mayo Clinic Hospital - Saint Marys Campus

howard

Rp2.115.601

Rp2.435.586 total

includes taxes & fees

12 Nov - 13 Nov

A spacious, modern office with a high ceiling, a reception desk, and a seating area with chairs.

A modern interior with a large dining table, sofas, and a kitchen area.

A spacious living area with a modern staircase, leather sofas, and contemporary lighting.

A modern pool table in a spacious, well-lit room with large windows and a bar area.

4. The Berkman

Folwell, 0.1 km from Mayo Clinic Hospital - Saint Marys Campus

Suzette

Rp3.402.432

Rp3.956.251 total

includes taxes & fees

13 Nov - 14 Nov

A coffee shop interior with a wooden counter, menu boards, and seating area.

An outdoor seating area with tables and chairs, a neon sign, and flower arrangements.

A hotel exterior with a 'Townplace Suites' sign, outdoor seating area, and 'OPEN' signage.

A hotel room with a bed, bedside table, and a window with curtains.

5. TownePlace Suites by Marriott Rochester Mayo Clinic Area

Kutzky Park, 1 km from Mayo Clinic Hospital - Saint Marys Campus

Cory

Rp2.452.300

Rp2.823.209 total

includes taxes & fees

23 Oct - 24 Oct

A rooftop terrace with outdoor seating and a city skyline in the background.

A hotel room with a bed, a desk, a chair, a TV, and a window with a city view.

A modern bathroom with a white sink, wooden cabinet, and a decorative wall panel.

A hotel room with a sofa, armchair, and a coffee table.

6. Hilton Rochester Mayo Clinic Area

Downtown Rochester, 1.7 km from Mayo Clinic Hospital - Saint Marys Campus

Raymond

Rp3.179.935

Rp3.660.899 total

includes taxes & fees

7 Nov - 8 Nov

A modern indoor patio with a fire feature, seating, and large windows.

A reception area with a curved reception desk, wooden shelving, and a green moss wall with the text "I ♥ EVEN".

A modern living room with a fireplace, large windows, and a flat-screen TV mounted on the wall.

A modern interior with a seating area, a bookshelf, and a window with a view of trees.

7. EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kutzky Park, 0.4 km from Mayo Clinic Hospital - Saint Marys Campus

James

Rp2.038.810

Rp2.382.980 total

includes taxes & fees

16 Oct - 17 Oct

A modern outdoor seating area with a built-in fireplace, two wooden chairs, a table, and a sofa.

A gym with various exercise equipment, including treadmills, stationary bikes, and weight machines.

A modern kitchen with a central island, bar stools, and pendant lighting. A living area with a sofa, ottoman, and a view of the outdoors is visible.

A hotel room with a kitchenette, a bed, a sofa, a small table, and a window with curtains.

8. Staybridge Suites Rochester - Mayo Clinic Area by IHG

Kutzky Park, 0.4 km from Mayo Clinic Hospital - Saint Marys Campus

Sheri

Rp2.040.600

Rp2.385.042 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.

A modern indoor pool area with lounge chairs and a pool.

A modern dining area with round tables and chairs, a large painting on the wall, and a flat-screen TV mounted above a geometric-patterned wall.

A modern Hyatt House hotel with a prominent 'Hyatt House' sign, multiple floors, and a parking garage.

9. Hyatt House Rochester/Mayo Clinic Area

Downtown Rochester, 1.6 km from Mayo Clinic Hospital - Saint Marys Campus

Elsie

Rp2.112.200

Rp2.431.670 total

includes taxes & fees

23 Oct - 24 Oct

A Courtyard Marriott hotel with multiple floors, a brick facade, and illuminated signage.

A hotel room with a bed, a sofa, a desk, a TV, and a wall art piece.

A conference room with a long table, multiple chairs, and decorative wall art.

A hotel room with a sofa, armchairs, a small kitchenette, a flat-screen TV, and a large window.

10. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Kutzky Park, 0.2 km from Mayo Clinic Hospital - Saint Marys Campus

MATTHEW

Rp2.023.934

Rp2.330.055 total

includes taxes & fees

6 Nov - 7 Nov

A modern kitchen with a dark countertop, black cabinets, a microwave, and a refrigerator. There are two pendant lights above the counter.

A hotel room with a large round table, two sofas, a TV, and a bed.

A storage cabinet with multiple shelves containing kitchen appliances, glassware, and board games.

A reception area with a clock, a counter, and a nameplate.

11. Candlewood Suites Rochester Mayo Clinic Area by IHG

2.9 km from Mayo Clinic Hospital - Saint Marys Campus

Kevin

Rp2.076.748

Rp2.390.856 total

includes taxes & fees

17 Oct - 18 Oct

A bedroom with a large bed, a TV on a dresser, and a view of the city through large windows.

An indoor swimming pool with a clock on the wall, lounge chairs, and a lifeguard warning sign.

A multi-story building with the sign 'Broadway Plaza' indicating a commercial or hotel property.

A modern kitchen with wooden cabinets, a granite countertop, and a stainless steel stove.

12. Broadway Plaza, Trademark Collection by Wyndham

Downtown Rochester, 1.7 km from Mayo Clinic Hospital - Saint Marys Campus

Danny

Rp3.027.785

Rp3.485.737 total

includes taxes & fees

24 Oct - 25 Oct

An outdoor patio with a brick floor, stone fireplace, and wooden pergola.

A gym with exercise equipment, a clock, and a window with blinds.

A conference room with multiple tables and chairs, ceiling fans, and artwork on the walls.

An indoor swimming pool with clear pool rules posted on the wall, a lifeguard chair, and a pool lift sign.

13. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Kutzky Park, 0.2 km from Mayo Clinic Hospital - Saint Marys Campus

Lin

Rp2.114.885

Rp2.434.761 total

includes taxes & fees

7 Nov - 8 Nov

A reception area with a wooden reception desk, a "Welcome to the Bread & Butter State" sign, and a "Please Center" sign.

A pool area with a table and chairs, a lifeguard chair, and a pool lift.

A coffee station with four coffee dispensers, a stack of disposable cups, and a tray with various coffee-related items.

A hotel room with a bed, a desk, a chair, a TV, and a bathroom visible through an open door.

14. Hampton Inn Rochester-South

3.1 km from Mayo Clinic Hospital - Saint Marys Campus

dennis

Rp1.962.735

Rp2.259.599 total

includes taxes & fees

25 Oct - 26 Oct

A hotel entrance with a stone facade, a glass door, and a metal roof structure.

A hotel room with a kitchenette, a dining area with striped chairs, a sofa, a TV, and a window with curtains.

A spa area with a hot tub, exercise equipment, and a seating area with chairs and a table.

A hotel lobby with striped armchairs, a sofa, a fireplace, and a clock on the wall.

15. Aspen Suites

0.2 km from Mayo Clinic Hospital - Saint Marys Campus

Dana

Rp2.537.799

Rp3.067.723 total

includes taxes & fees

24 Oct - 25 Oct

A spacious outdoor dining area with modern furniture and large windows offering views of the city.

A modern interior with a wooden ceiling, a large black shelving unit, and a refrigerator stocked with beverages.

A modern hotel room with a large bed, a sofa, a small table, a desk, and a wardrobe.

An outdoor dining area with wooden beams, tables, and chairs.

16. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Downtown Rochester, 1.7 km from Mayo Clinic Hospital - Saint Marys Campus

Hernan

Rp1.844.009

Rp2.122.915 total

includes taxes & fees

13 Nov - 14 Nov

A room with a fireplace, two leather armchairs, a sofa, and a large window providing a view of the outdoors.

A paved garden area with two benches, a potted plant with yellow flowers, and a variety of greenery.

A long, narrow hotel corridor with a carpeted floor, light fixtures along the walls, and a ceiling with recessed lighting.

A hotel room with a bed, a sink, a microwave, and a window with curtains.

17. Brentwood Inn & Suites

Downtown Rochester, 1.3 km from Mayo Clinic Hospital - Saint Marys Campus

Daniel

Rp2.237.875

Rp2.576.421 total

includes taxes & fees

5 Nov - 6 Nov

A hotel breakfast area with a self-serve station, including a waffle maker, toaster, and various food items.

A modern living room with a sofa, coffee table, and a TV mounted on a stone wall.

A hotel room with a large bed, bedside tables, a mirror, and a patterned carpet.

A hotel lobby with a patterned carpet, two beige armchairs, a small table, a clock, a fire extinguisher, and a staircase.

18. Quality Inn & Suites Mayo Clinic Area

2.9 km from Mayo Clinic Hospital - Saint Marys Campus

Jessica

Rp1.319.230

Rp1.538.095 total

includes taxes & fees

6 Nov - 7 Nov

A hotel room with two beds, a desk, a lamp, a nightstand, and a vase with flowers.

A spacious lobby with a large seating area, a fireplace, and large windows providing natural light.

A grocery store with refrigerated and frozen sections, shelves stocked with snacks, and a variety of beverages.

A spacious hotel lobby with multiple seating areas, including sofas and round tables, and a large dining area with yellow chairs.

19. Hilton Garden Inn Rochester Downtown, MN

Downtown Rochester, 1.6 km from Mayo Clinic Hospital - Saint Marys Campus

Richard

Rp2.114.885

Rp2.434.761 total

includes taxes & fees

24 Oct - 25 Oct

An outdoor patio area with yellow umbrellas, wicker furniture, and a sign for Centerstone Plaza Hotel.

A restaurant interior with wooden tables, chairs, and a stone wall.

A modern living room with a dark wall, a decorative light fixture, and a patterned wall art piece.

A garden with a water feature, rocks, and yellow umbrellas.

20. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Historic Southwest, 1.2 km from Mayo Clinic Hospital - Saint Marys Campus

Christine

Rp2.044.175

Rp2.353.357 total

includes taxes & fees

23 Oct - 24 Oct

View all properties

Compare popular hotels close to Mayo Clinic Hospital - Saint Marys Campus

Property	Property class	Guest rating
Residence Inn by Marriott Rochester Mayo Clinic Area South	9.6 Exceptional 316 reviews	View
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys	9.6 Exceptional 743 reviews	View
Home2 Suites by Hilton Rochester Mayo Clinic Area	9.6 Exceptional 1,000 reviews	View
The Berkman	9.6 Exceptional 448 reviews	View
TownePlace Suites by Marriott Rochester Mayo Clinic Area	9.6 Exceptional 568 reviews	View

Top Mayo Clinic Hospital - Saint Marys Campus Hotel Reviews

Aspen Select

10/10 Excellent

"Great stay with a very helpful staff."

Hotel Indigo Rochester – Mayo Clinic Area by IHG

8/10 Good

"We checked in at 8:30 p.m. When we got close to our room, the cleaning carts were in the way. We moved them. At 9:25, the sweeper started next door. We retired early and were in bed. Loud! The shuttle service is super. Asked for a invoice and could not get one. Would use this again because of the location."

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

10/10 Excellent

"Always a welcoming team with excellent amenities. Spotlessly clean. I always feel at home here."

AmericInn by Wyndham Rochester Near Mayo Clinic

10/10 Excellent

"the shuttle to the mayo was great however you have to plan for at least 1 hr for the return trip. The down fall is that so many people in Rochester going to the mayo may be in a wheelchair, like myself and a very rare amount of shuttles form hotels are handicap accessible. This hotel work because I did not join my husband."

Med City Inn & Suites - Mayo Clinic Area

8/10 Good

"Perfect location for me."

EVEN Hotel Rochester - Mayo Clinic Area by IHG

8/10 Good

"Booked the property for the underground parking, it was sold out! Very misleading. Power went out during the night, not the staffs fault but surprised there was no generator, hotel was pitch black!"

Staybridge Suites Rochester - Mayo Clinic Area by IHG

10/10 Excellent

"Muy buena atención"

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

10/10 Excellent

"Good! Didn’t use the pool but it looked great, especially for families with kids! Just peeked in quick at the breakfast to get a few things and it was good!"

TownePlace Suites by Marriott Rochester Mayo Clinic Area

8/10 Good

"AC unit very loud. Bed has had its useful life, it was bad and needs to be replaced."

Frequently asked questions

What's the area like around Mayo Clinic Hospital - Saint Marys Campus?

Mayo Clinic Hospital - Saint Marys Campus is located in a welcoming area of Rochester known for its major shopping area. If you're looking for a convenient place to stay, take a look at the 123 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay near Mayo Clinic Hospital - Saint Marys Campus?

Adjacent to Mayo Clinic Hospital - Saint Marys Campus, The Berkman is one of the top choices for your stay based on our traveller data, and this aparthotel offers in-room kitchens and a fitness centre. Other good options within a short distance include Kahler Grand Hotel and Kahler Inn and Suites - Mayo Clinic Area.

How many hotels are there close to Mayo Clinic Hospital - Saint Marys Campus?

Expedia has 123 hotels and other accommodation options within a mile from Mayo Clinic Hospital - Saint Marys Campus.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Hospital - Saint Marys Campus, will I receive a refund?

Yes! The majority of room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within 24 hours of your booking. Put your dates in and click on "Search", then filter by "fully refundable" to view the best options available near Mayo Clinic Hospital - Saint Marys Campus.

What can I see and do near Mayo Clinic Hospital - Saint Marys Campus?

You'll want to browse the exhibits at Mayowood Mansion and History Center of Olmsted County. Sights like Assisi Heights and Plummer House highlight some of the local culture. You can enjoy live performances at Rochester Civic Theater and Marcus Rochester Cinema.

Search Hotels Near Mayo Clinic Hospital - Saint Marys Campus, Rochester

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Our top choices for Mayo Clinic Hospital - Saint Marys Campus hotels

1. Residence Inn by Marriott Rochester Mayo Clinic Area South

2. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

3. Home2 Suites by Hilton Rochester Mayo Clinic Area

4. The Berkman

5. TownePlace Suites by Marriott Rochester Mayo Clinic Area

6. Hilton Rochester Mayo Clinic Area

7. EVEN Hotel Rochester - Mayo Clinic Area by IHG

8. Staybridge Suites Rochester - Mayo Clinic Area by IHG

9. Hyatt House Rochester/Mayo Clinic Area

10. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

11. Candlewood Suites Rochester Mayo Clinic Area by IHG

12. Broadway Plaza, Trademark Collection by Wyndham

13. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

14. Hampton Inn Rochester-South

15. Aspen Suites

16. Hotel Indigo Rochester – Mayo Clinic Area by IHG

17. Brentwood Inn & Suites

18. Quality Inn & Suites Mayo Clinic Area

19. Hilton Garden Inn Rochester Downtown, MN

20. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Compare popular hotels close to Mayo Clinic Hospital - Saint Marys Campus

Top Mayo Clinic Hospital - Saint Marys Campus Hotel Reviews

Aspen Select

Hotel Indigo Rochester – Mayo Clinic Area by IHG

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

AmericInn by Wyndham Rochester Near Mayo Clinic

Med City Inn & Suites - Mayo Clinic Area

EVEN Hotel Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

TownePlace Suites by Marriott Rochester Mayo Clinic Area

Frequently asked questions