The Best Hotels Closest to Mayo Clinic Hospital - Saint Marys Campus in Rochester - 2026 Updated Prices

An aerial view of a campus with multiple buildings, parking lots, and surrounding greenery.

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Our top choices for Mayo Clinic Hospital - Saint Marys Campus hotels

An outdoor patio area with a concrete floor, wooden fence, and string lights.

A modern living room with a stone fireplace, a blue armchair, a round coffee table, and a large window offering a view of the outdoors.

A Fairfield Inn & Suites hotel with a modern design, featuring a prominent entrance and a parking area.

1. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Kutzky Park, 0.9 km from Mayo Clinic Hospital - Saint Marys Campus

Jon

Rp1.974.539

Rp2.273.187 total

includes taxes & fees

18 Sept - 19 Sept

An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.

A modern restaurant with a counter, seating area, and a TV screen.

A modern hotel room with a bed, desk, and kitchenette.

A modern lounge area with a sofa, chairs, and tables.

2. Home2 Suites by Hilton Rochester Mayo Clinic Area

2.3 km from Mayo Clinic Hospital - Saint Marys Campus

Vickie

Rp2.161.731

Rp2.488.694 total

includes taxes & fees

5 Sept - 6 Sept

A swimming pool with clear blue water, surrounded by lounge chairs and a view of residential buildings through large windows.

A modern hotel with a flat roof, multiple windows, and a covered outdoor seating area.

A modern reception area with a brick-patterned wall, two reception desks, a flat-screen TV, and seating arrangements including a sofa and chairs.

An outdoor patio area with wicker furniture, a central fire feature, and a stone building in the background.

3. Residence Inn by Marriott Rochester Mayo Clinic Area South

2.3 km from Mayo Clinic Hospital - Saint Marys Campus

Richard

Rp2.512.406

Rp2.892.407 total

includes taxes & fees

6 Sept - 7 Sept

A spacious living area with a modern staircase, leather sofas, and contemporary lighting.

A modern pool table in a spacious, well-lit room with large windows and a bar area.

A modern interior with a large dining table, sofas, and a kitchen area.

An outdoor seating area with blue sofas and wicker chairs, a wooden table, and green ottomans on a tiled patio.

4. The Berkman

Folwell, 0.1 km from Mayo Clinic Hospital - Saint Marys Campus

William

Rp3.135.377

Rp3.645.643 total

includes taxes & fees

1 Sept - 2 Sept

A coffee shop interior with a wooden counter, menu boards, and seating area.

An outdoor seating area with tables and chairs, a neon sign, and flower arrangements.

A hotel room with a bed, bedside table, and a window with curtains.

5. TownePlace Suites by Marriott Rochester Mayo Clinic Area

Kutzky Park, 1 km from Mayo Clinic Hospital - Saint Marys Campus

Jorge

Rp2.247.011

Rp2.586.872 total

includes taxes & fees

4 Sept - 5 Sept

A modern living room with a flat-screen TV, a fireplace, comfortable seating, and a large window with a city view.

A modern hotel lobby with a curved staircase, seating areas, and large windows.

A modern hotel entrance with a glass facade, illuminated signage, and a covered walkway.

A modern indoor swimming pool with seating areas and a city view.

6. Hilton Rochester Mayo Clinic Area

Downtown Rochester, 1.7 km from Mayo Clinic Hospital - Saint Marys Campus

Jennifer

Rp3.177.309

Rp3.657.878 total

includes taxes & fees

11 Sept - 12 Sept

A modern indoor patio with a fire feature, seating, and large windows.

A modern living room with a fireplace, large windows, and a flat-screen TV mounted on the wall.

A reception area with a curved reception desk, wooden shelving, and a green moss wall with the text "I ♥ EVEN".

A modern hotel lobby with a large glass wall, a green wall mural, and a seating area with sofas and chairs.

7. EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kutzky Park, 0.4 km from Mayo Clinic Hospital - Saint Marys Campus

paul

Rp1.857.765

Rp2.377.828 total

includes taxes & fees

4 Sept - 5 Sept

A modern outdoor seating area with a built-in fireplace, two wooden chairs, a table, and a sofa.

A hotel room with a kitchenette, a bed, a sofa, a small table, and a window with curtains.

A gym with various exercise equipment, including treadmills, stationary bikes, and weight machines.

A modern interior with a dining area, a kitchen, and a pantry stocked with snacks.

8. Staybridge Suites Rochester - Mayo Clinic Area by IHG

Kutzky Park, 0.4 km from Mayo Clinic Hospital - Saint Marys Campus

matthew

Rp1.822.379

Rp2.133.399 total

includes taxes & fees

5 Sept - 6 Sept

An outdoor patio with a brick floor, stone fireplace, and wooden pergola.

A conference room with multiple tables and chairs, ceiling fans, and artwork on the walls.

A modern hotel lobby with a stone wall fireplace, comfortable seating, and a chandelier.

An indoor swimming pool with clear pool rules posted on the wall, a lifeguard chair, and a pool lift sign.

9. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Kutzky Park, 0.2 km from Mayo Clinic Hospital - Saint Marys Campus

Lin

Rp2.016.648

Rp2.321.666 total

includes taxes & fees

11 Sept - 12 Sept

A Courtyard Marriott hotel with multiple floors, a brick facade, and illuminated signage.

A modern living room with a sofa, a round coffee table, and a side table. There are large windows with a view of the outside.

A hotel room with a sofa, armchairs, a small kitchenette, a flat-screen TV, and a large window.

A hotel room with a bed, a sofa, a desk, a TV, and a wall art piece.

10. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Kutzky Park, 0.2 km from Mayo Clinic Hospital - Saint Marys Campus

MATTHEW

Rp1.832.110

Rp2.109.217 total

includes taxes & fees

18 Sept - 19 Sept

A hotel room with a large round table, two sofas, a TV, and a bed.

A reception area with a clock, a counter, and a nameplate.

A hotel lobby with a reception desk, seating area, and a large window.

A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

11. Candlewood Suites Rochester Mayo Clinic Area by IHG

2.9 km from Mayo Clinic Hospital - Saint Marys Campus

Sean

Rp2.052.388

Rp2.362.811 total

includes taxes & fees

4 Sept - 5 Sept

A reception area with a wooden reception desk, a "Welcome to the Bread & Butter State" sign, and a "Please Center" sign.

A hotel room with a bed, a desk, a chair, a TV, and a bathroom visible through an open door.

A coffee station with four coffee dispensers, a stack of disposable cups, and a tray with various coffee-related items.

A pool area with a table and chairs, a lifeguard chair, and a pool lift.

12. Hampton Inn Rochester-South

3.1 km from Mayo Clinic Hospital - Saint Marys Campus

Lynne

Rp1.668.450

Rp1.920.803 total

includes taxes & fees

1 Oct - 2 Oct

A bedroom with a large bed, a TV on a dresser, and a view of the city through large windows.

An indoor swimming pool with a clock on the wall, lounge chairs, and a lifeguard warning sign.

A multi-story building with the sign 'Broadway Plaza' indicating a commercial or hotel property.

A modern kitchen with wooden cabinets, a granite countertop, and a stainless steel stove.

13. Broadway Plaza, Trademark Collection by Wyndham

Downtown Rochester, 1.7 km from Mayo Clinic Hospital - Saint Marys Campus

Camille

Rp3.143.161

Rp3.618.563 total

includes taxes & fees

11 Sept - 12 Sept

A hotel entrance with a stone facade, a glass door, and a metal roof structure.

A spa area with a hot tub, exercise equipment, and a seating area with chairs and a table.

A hotel lobby with striped armchairs, a sofa, a fireplace, and a clock on the wall.

An outdoor patio area with brick walls, a large arched window, and outdoor seating.

14. Aspen Suites

0.2 km from Mayo Clinic Hospital - Saint Marys Campus

Dr. suzette

Rp2.240.818

Rp2.708.729 total

includes taxes & fees

3 Sept - 4 Sept

An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.

A modern bar area with seating and a counter.

A modern indoor pool area with lounge chairs and a pool.

A modern dining area with round tables and chairs, a large painting on the wall, and a flat-screen TV mounted above a geometric-patterned wall.

15. Hyatt House Rochester/Mayo Clinic Area

Downtown Rochester, 1.6 km from Mayo Clinic Hospital - Saint Marys Campus

Mary Jo

Rp2.247.011

Rp2.586.871 total

includes taxes & fees

1 Oct - 2 Oct

A room with a fireplace, two leather armchairs, a sofa, and a large window providing a view of the outdoors.

A paved garden area with two benches, a potted plant with yellow flowers, and a variety of greenery.

A reception area with a curved counter, ceiling lights, and a potted plant.

A hotel room with a bed, a sink, a microwave, and a window with curtains.

16. Brentwood Inn & Suites

Downtown Rochester, 1.3 km from Mayo Clinic Hospital - Saint Marys Campus

Bryan

Rp2.211.625

Rp2.546.200 total

includes taxes & fees

3 Sept - 4 Sept

A modern lobby with a reception desk, a green sofa, and a black spherical table.

A modern bar area with a central island, bar stools, and hanging spherical light fixtures.

A modern hotel with a prominent 'Hotel Indigo' sign, a 'Crave Drink' restaurant, and a well-lit facade.

An indoor dining area with wooden ceiling beams, large windows, and modern furniture.

17. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Downtown Rochester, 1.7 km from Mayo Clinic Hospital - Saint Marys Campus

Kyle

Rp1.822.379

Rp2.098.013 total

includes taxes & fees

4 Sept - 5 Sept

A spacious hotel lobby with multiple seating areas, including sofas and round tables, and a large dining area with yellow chairs.

A spacious lobby with a large seating area, a fireplace, and large windows providing natural light.

A grocery store with refrigerated and frozen sections, shelves stocked with snacks, and a variety of beverages.

A reception area with two counters, a patterned wall, and a wooden floor.

18. Hilton Garden Inn Rochester Downtown, MN

Downtown Rochester, 1.6 km from Mayo Clinic Hospital - Saint Marys Campus

Eileen

Rp2.016.648

Rp2.321.666 total

includes taxes & fees

11 Sept - 12 Sept

A hotel breakfast area with a self-serve station, including a waffle maker, toaster, and various food items.

A modern living room with a sofa, coffee table, and a TV mounted on a stone wall.

A compact kitchen with a microwave, refrigerator, and coffee maker. A small bar stool is near the counter.

A hotel room with a large bed, bedside tables, a mirror, and a patterned carpet.

19. Quality Inn & Suites Mayo Clinic Area

2.9 km from Mayo Clinic Hospital - Saint Marys Campus

Cassandra

Rp1.353.515

Rp1.577.342 total

includes taxes & fees

5 Sept - 6 Sept

An outdoor patio area with yellow umbrellas, wicker furniture, and a sign for Centerstone Plaza Hotel.

A garden with a water feature, rocks, and yellow umbrellas.

A modern living room with a dark wall, a decorative light fixture, and a patterned wall art piece.

A restaurant interior with wooden tables, chairs, and a stone wall.

20. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Historic Southwest, 1.2 km from Mayo Clinic Hospital - Saint Marys Campus

Sarah

Rp2.020.536

Rp2.326.142 total

includes taxes & fees

4 Sept - 5 Sept

View all properties

Compare popular hotels close to Mayo Clinic Hospital - Saint Marys Campus

Property	Property class	Guest rating
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys	9.6 Exceptional 737 reviews	View
Home2 Suites by Hilton Rochester Mayo Clinic Area	9.6 Exceptional 1,003 reviews	View
Residence Inn by Marriott Rochester Mayo Clinic Area South	9.6 Exceptional 302 reviews	View
The Berkman	9.6 Exceptional 430 reviews	View
TownePlace Suites by Marriott Rochester Mayo Clinic Area	9.6 Exceptional 553 reviews	View

Top Mayo Clinic Hospital - Saint Marys Campus Hotel Reviews

Aspen Select

10/10 Excellent

"Very good experience. Accommodating to our needs."

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

8/10 Good

"The property was great, swim pool was nice. Arcade needs some work and repairs guy to come but that was ok. Staff nice and the room was clean and comfy."

Hyatt House Rochester/Mayo Clinic Area

8/10 Good

"Easy place to get to; helpful staff. We had a large room. The hotel was quiet. Hot tub out of order and our room was ovwrlooking the train track which, unfortunately, had a train come through in the middle of the night and woke us all up. It had a nice terrace on our floor for relaxing."

Kahler Grand Hotel

8/10 Good

"The room was clean, but dated the bathroom was clean but old ,water leaked out of the shower to the floor Nothing you can do about ,it faucets very old didn't work real well. Not enough staff at front desk. Other than that price right and central in the subway system to go to the Mayo Clinic. I travel to mayo every three months. I would probably stay again."

Aspen Suites

10/10 Excellent

"Comfortable and clean. Nice pool and hot tub. Great breakfast and during the week there is a light supper. Just steps from St. Mary's Mayo hospital. Underground parking a great shuttle."

Brentwood Inn & Suites

10/10 Excellent

"My room was very clean, the staff were friendly and helpful, and the room rate for two queen beds was very reasonable."

Staybridge Suites Rochester - Mayo Clinic Area by IHG

10/10 Excellent

"Great property. Free breakfast, happy hour a few days, huge lobby and patio are. Convenient shuttle to Mayo Clinic. Fully stocked kitchens, coffee, and dishwasher. Laundry on site if needed."

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

8/10 Good

"Check out was very confusing. It took about a half hour and I am still not sure if the billing was correct. Food was fine."

Kahler Inn and Suites - Mayo Clinic Area

10/10 Excellent

"The hotel was nice and clean, staff were very pleasant, breakfast was a big tasty buffet. The only complaint was the parking garage was very little and barely fit my mid size SUV because of how low the ceiling was, but there is another garage next to the hotel that was actually cheaper. Also, being on the side where all the construction was going on, but I get it they had to start super early because of the heat. Most importantly though it was with walking distance from all of my Mayo appts and several restaurants."

Frequently asked questions

What's the area like around Mayo Clinic Hospital - Saint Marys Campus?

Mayo Clinic Hospital - Saint Marys Campus is located in a welcoming area of Rochester known for its major shopping area. If you're looking for a convenient place to stay, take a look at the 126 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay near Mayo Clinic Hospital - Saint Marys Campus?

Adjacent to Mayo Clinic Hospital - Saint Marys Campus, EVEN Hotel Rochester - Mayo Clinic Area by IHG is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an indoor pool. Other good options within a short distance include Kahler Grand Hotel and Kahler Inn and Suites - Mayo Clinic Area.

How many hotels are there close to Mayo Clinic Hospital - Saint Marys Campus?

Expedia has 126 hotels and other accommodation options within a mile from Mayo Clinic Hospital - Saint Marys Campus.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Hospital - Saint Marys Campus, will I receive a refund?

Yes! The majority of room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within 24 hours of your booking. Put your dates in and click on "Search", then filter by "fully refundable" to view the best options available near Mayo Clinic Hospital - Saint Marys Campus.

What can I see and do near Mayo Clinic Hospital - Saint Marys Campus?

You'll want to browse the exhibits at Mayowood Mansion and History Center of Olmsted County. Sights like Plummer House and Assisi Heights highlight some of the local culture. You can enjoy live performances at Rochester Civic Theater and Marcus Rochester Cinema.

Search Hotels Near Mayo Clinic Hospital - Saint Marys Campus, Rochester

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Our top choices for Mayo Clinic Hospital - Saint Marys Campus hotels

1. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

2. Home2 Suites by Hilton Rochester Mayo Clinic Area

3. Residence Inn by Marriott Rochester Mayo Clinic Area South

4. The Berkman

5. TownePlace Suites by Marriott Rochester Mayo Clinic Area

6. Hilton Rochester Mayo Clinic Area

7. EVEN Hotel Rochester - Mayo Clinic Area by IHG

8. Staybridge Suites Rochester - Mayo Clinic Area by IHG

9. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

10. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

11. Candlewood Suites Rochester Mayo Clinic Area by IHG

12. Hampton Inn Rochester-South

13. Broadway Plaza, Trademark Collection by Wyndham

14. Aspen Suites

15. Hyatt House Rochester/Mayo Clinic Area

16. Brentwood Inn & Suites

17. Hotel Indigo Rochester – Mayo Clinic Area by IHG

18. Hilton Garden Inn Rochester Downtown, MN

19. Quality Inn & Suites Mayo Clinic Area

20. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Compare popular hotels close to Mayo Clinic Hospital - Saint Marys Campus

Top Mayo Clinic Hospital - Saint Marys Campus Hotel Reviews

Aspen Select

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

Kahler Grand Hotel

Aspen Suites

Brentwood Inn & Suites

Staybridge Suites Rochester - Mayo Clinic Area by IHG

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

Kahler Inn and Suites - Mayo Clinic Area

Frequently asked questions