Downtown South San Francisco Travel Guide

San Francisco

Aerial View of a Local High School and an Athletic Field in a Neighborhood in South San Francisco, California, USA
Aerial view of the South San Francisco area
Aerial view of downtown San Francisco and Financial District sky scrapers flying over South San Francisco The Industrial City inscription on San Bruno mountain circa 2015

Popular places to visit

Things to do


Top hotels in Downtown South San Francisco

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3 out of 5
20 Airport Blvd South San Francisco CA
The price is Rp2.066.696 per night from 29 May to 30 May
Rp2.066.696
Rp2.420.487 total
29 May - 30 May
includes taxes & fees
Stay at this business-friendly hotel in South San Francisco. Enjoy free breakfast, free Wi-Fi and a free airport shuttle. Our guests praise the breakfast and ...
8.2/10 Very Good! (1,990 reviews)
"Buen hotel bien limpio buen habiente los trabajadores son muy amables los recomiendo 100por ciento"

Reviewed on 28 May 2026

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is Rp3.542.618 per night from 8 Jun to 9 Jun
Rp3.542.618
Rp4.902.886 total
8 Jun - 9 Jun
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the ...
9/10 Wonderful! (7,472 reviews)
"Bright sun-filled rooms."

Reviewed on 28 May 2026

Hotel Riu Plaza Fisherman's Wharf
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
The price is Rp2.385.334 per night from 31 May to 1 Jun
Rp2.385.334
Rp2.807.419 total
31 May - 1 Jun
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness centre and Wi-Fi (surcharge). Our guests praise the helpful staff ...
8.8/10 Excellent! (2,819 reviews)
"Great location Very friendly staff"

Reviewed on 27 May 2026

Hilton San Francisco Financial District
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
The price is Rp2.652.349 per night from 28 Jun to 29 Jun
Rp2.652.349
Rp3.121.683 total
28 Jun - 29 Jun
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the pool and the ...
9/10 Wonderful! (5,799 reviews)
"I was very pleased with my stay. Prompt and fast check in with corteous staff. Room and bath area very clean. Room cooled (room faced west with large windows) at arrival. Overall I give it 5 stars and plan to stay again on an upcoming visit in a few months."

Reviewed on 28 May 2026

Holiday Inn Golden Gateway by IHG
Hilton San Francisco Union Square

Hilton San Francisco Union Square

4 out of 5
333 O'Farrell St. San Francisco CA
The price is Rp3.313.656 per night from 19 Jun to 20 Jun
Rp3.313.656
Rp3.900.006 total
19 Jun - 20 Jun
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy 2 bars/lounges, breakfast (surcharge) and a 24-hour health club. Our guests praise the helpful staff ...
8.6/10 Excellent! (1,323 reviews)
"Everything was average I would say for room and amenities. Rooms are a bit outdated. My problem was with the employee that checked us in. She was rude and dismissive, she wouldn't talk to us at all, not even to instruct me on paying for the deposit nor did she explain what the deposit was for. Offered ..."

Reviewed on 27 May 2026

Hilton San Francisco Union Square
Parc 55 San Francisco - A Hilton Hotel

Parc 55 San Francisco - A Hilton Hotel

4 out of 5
55 Cyril Magnin St San Francisco CA
The price is Rp3.162.348 per night from 19 Jun to 20 Jun
Rp3.162.348
Rp3.722.011 total
19 Jun - 20 Jun
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy 2 restaurants, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the helpful ...
8.6/10 Excellent! (1,487 reviews)
"Good service"

Reviewed on 28 May 2026

Parc 55 San Francisco - A Hilton Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Downtown South San Francisco

Aerial View Of Urban Neighborhood

Noe Valley

Appreciated for its churches and architecture, you might consider exploring Noe Valley. Check out the variety of things to see and do like 22nd St Hill, and jump on the metro at Church St & Clipper St Stop or Church St & 24th St Stop to get around the city.

Noe Valley
Mission District

Mission District

3.5/5(11 area reviews)

You might enjoy the bars while in Mission District. SOMA Pilipinas is a notable sight, and you can get around town at 16th Street Mission Station or 24th Street Mission Station to see more of the city.

Mission District
Potrero Hill

Potrero Hill

The live music and architecture are just a few things visitors like about Potrero Hill. San Francisco Bay and Museum of Craft & Design are worthwhile spots to check out, and you can hop on the metro at 20th Street Station or 23rd Street Station to get around the larger area.

Potrero Hill
Sunset District

Sunset District

3.5/5(6 area reviews)

Consider exploring the beaches in Sunset District. If sightseeing is on the list, Ocean Beach is a top attraction. Hop on the metro at Judah Street & Sunset Boulevard Station or Judah St & 34th Ave Stop to see more of the area.

Sunset District
South of Market

South of Market

3.5/5(115 area reviews)

Gourmet restaurants great entertainment and top sights from Oracle Park to San Francisco Bay – discover South of Market, a destination also famous for its shopping.

South of Market
Ariel view of the California Academy of Sciences in San Francisco, California.

Golden Gate

If you're spending time in Golden Gate, check out sights like San Francisco Botanical Garden or Japanese Tea Garden and hop on the metro to see more of the city at Irving St & 9th Ave Stop or Irving St & 8th Ave Stop.

Golden Gate


Downtown South San Francisco Travel Guide