Search Hotels in Sanctuary On Spruce Creek, Port Orange

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Sanctuary On Spruce Creek hotels

Daytona Grande Oceanfront Resort

Daytona Grande Oceanfront Resort
4.0 star property
17 km from Sanctuary On Spruce Creek
9.2 out of 10, Wonderful, (4276)
"Wonderful place to stay "
United States
Stacey
The price is Rp1.726.158
Rp2.507.950 total
includes taxes & fees
26 Jan - 27 Jan 2026
Daytona Grande Oceanfront Resort

The Shores Resort & Spa

The Shores Resort & Spa
4.0 star property
12 km from Sanctuary On Spruce Creek
9.0 out of 10, Wonderful, (1706)
"Overall stay its a great resort hotel"
United States
Elijah
The price is Rp2.214.611
Rp3.151.606 total
includes taxes & fees
4 Jan - 5 Jan 2026
The Shores Resort & Spa

Delta Hotels by Marriott Daytona Beach

Delta Hotels by Marriott Daytona Beach
3.5 star property
12.5 km from Sanctuary On Spruce Creek
9.2 out of 10, Wonderful, (1003)
"Great location, staff and amenities"
United States
JOSEPH ANDREW
The price is Rp1.999.103
Rp2.248.990 total
includes taxes & fees
4 Jan - 5 Jan 2026
Delta Hotels by Marriott Daytona Beach

Nautilus Inn

Nautilus Inn
2.5 star property
14.4 km from Sanctuary On Spruce Creek
9.2 out of 10, Wonderful, (3046)
"Just a nice, clean and friendly place to stay "
United States
sohrab
The price is Rp1.645.235
Rp1.850.890 total
includes taxes & fees
5 Jan - 6 Jan 2026
Nautilus Inn

Hilton Daytona Beach Oceanfront Resort

Hilton Daytona Beach Oceanfront Resort
4.0 star property
16.5 km from Sanctuary On Spruce Creek
7.4 out of 10, Good, (4993)
"Great stay"
United States
ashley
The price is Rp2.163.459
Rp2.905.659 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton Daytona Beach Oceanfront Resort

Hard Rock Hotel Daytona Beach

Hard Rock Hotel Daytona Beach
4.0 star property
17.8 km from Sanctuary On Spruce Creek
9.2 out of 10, Wonderful, (1636)
"Location of our room and friendliness of staff."
United States
Steven
The price is Rp2.551.708
Rp3.606.583 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hard Rock Hotel Daytona Beach

Days Inn by Wyndham Daytona Oceanfront

Days Inn by Wyndham Daytona Oceanfront
2.5 star property
10 km from Sanctuary On Spruce Creek
8.6 out of 10, Excellent, (1957)
"Great place to stay "
United States
Kathy
The price is Rp1.268.726
Rp1.578.089 total
includes taxes & fees
4 Jan - 5 Jan 2026
Days Inn by Wyndham Daytona Oceanfront

Bahama House

Bahama House
3.0 star property
13.9 km from Sanctuary On Spruce Creek
9.2 out of 10, Wonderful, (1852)
"Great place , great location , super friendly staff Highly recommended "
United States
Robert
Bahama House

The Riverview Hotel

The Riverview Hotel
3.0 star property
13.6 km from Sanctuary On Spruce Creek
9.4 out of 10, Exceptional, (960)
"Great location and friendly staff."
United States
PAMELA R
The price is Rp2.248.991
Rp2.718.747 total
includes taxes & fees
7 Jan - 8 Jan 2026
The Riverview Hotel

Coral Sands Inn

Coral Sands Inn
2.5 star property
26.1 km from Sanctuary On Spruce Creek
9.4 out of 10, Exceptional, (1280)
"Great property, rooms and view "
United States
Amanda
The price is Rp1.418.827
Rp1.596.264 total
includes taxes & fees
4 Jan - 5 Jan 2026
Coral Sands Inn

The Salty Mermaid Oceanfront Hotel

The Salty Mermaid Oceanfront Hotel
2.5 star property
14.4 km from Sanctuary On Spruce Creek
9.6 out of 10, Exceptional, (387)
"Loved the retro motel feel with a modern decor and amenities. The direct access to the beach was fabulous!"
United States
Martha
The price is Rp2.498.879
Rp3.146.743 total
includes taxes & fees
7 Jan - 8 Jan 2026
The Salty Mermaid Oceanfront Hotel

Holiday Inn Express & Suites Oceanfront by IHG

Holiday Inn Express & Suites Oceanfront by IHG
2.5 star property
10.2 km from Sanctuary On Spruce Creek
8.0 out of 10, Very good, (1153)
"Staff was very nice and loved the location. "
United States
Iramaris
The price is Rp1.645.224
Rp1.850.877 total
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express & Suites Oceanfront by IHG

SpringHill Suites by Marriott New Smyrna Beach

SpringHill Suites by Marriott New Smyrna Beach
2.5 star property
14.1 km from Sanctuary On Spruce Creek
9.0 out of 10, Wonderful, (860)
"Fantastic location, great property, super staff!"
United States
Helene
The price is Rp3.003.686
Rp3.379.146 total
includes taxes & fees
13 Jan - 14 Jan 2026
SpringHill Suites by Marriott New Smyrna Beach

Holiday Inn Resort Daytona Beach Oceanfront by IHG

Holiday Inn Resort Daytona Beach Oceanfront by IHG
3.0 star property
14.3 km from Sanctuary On Spruce Creek
7.8 out of 10, Good, (1002)
"Yes, we had breakfast outside this morning, it was great. Also checking in was a breeze, man at the desk was professional, personable and had a great smile the whole time. We come back here year after year, good to see Shannon is still here ."
United States
Kevin
The price is Rp1.408.764
Rp2.087.989 total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Resort Daytona Beach Oceanfront by IHG

Boardwalk Inn and Suites

Boardwalk Inn and Suites
2.5 star property
15.7 km from Sanctuary On Spruce Creek
8.4 out of 10, Very good, (1615)
"Great stay."
United States
JOHN
Boardwalk Inn and Suites

Hilton Garden Inn Daytona Beach Oceanfront

Hilton Garden Inn Daytona Beach Oceanfront
3.0 star property
20.1 km from Sanctuary On Spruce Creek
8.4 out of 10, Very good, (1015)
"Rooms was clean, the staff was very friendly "
United States
Angela
The price is Rp1.722.146
Rp1.937.413 total
includes taxes & fees
6 Jan - 7 Jan 2026
Hilton Garden Inn Daytona Beach Oceanfront

Hampton Inn New Smyrna Beach

Hampton Inn New Smyrna Beach
2.5 star property
13.7 km from Sanctuary On Spruce Creek
8.6 out of 10, Excellent, (1004)
"Clean room, friendly staff, convenience to shopping and dining!"
United States
ron
The price is Rp2.049.081
Rp2.305.216 total
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn New Smyrna Beach

Perry's Ocean Edge Resort

Perry's Ocean Edge Resort
2.5 star property
13.3 km from Sanctuary On Spruce Creek
8.4 out of 10, Very good, (2358)
"Clean large room, comfortable bed, friendly staff. "
United States
D'Ann
The price is Rp2.836.815
Rp3.568.701 total
includes taxes & fees
29 Jan - 30 Jan 2026
Perry's Ocean Edge Resort

Country Inn & Suites by Radisson, Port Orange-Daytona, FL

Country Inn & Suites by Radisson, Port Orange-Daytona, FL
2.5 star property
2.7 km from Sanctuary On Spruce Creek
8.8 out of 10, Excellent, (1009)
"Would stay here again "
United States
Manuel
The price is Rp1.646.903
Rp1.852.766 total
includes taxes & fees
8 Jan - 9 Jan 2026
Country Inn & Suites by Radisson, Port Orange-Daytona, FL

Best Western New Smyrna Beach Hotel & Suites

Best Western New Smyrna Beach Hotel & Suites
3.0 star property
15.2 km from Sanctuary On Spruce Creek
8.0 out of 10, Very good, (1002)
"Nice room, great location. No complaints."
United States
Corey
The price is Rp2.334.355
Rp2.626.149 total
includes taxes & fees
7 Jan - 8 Jan 2026
Best Western New Smyrna Beach Hotel & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Sanctuary On Spruce Creek

Find the best Sanctuary On Spruce Creek areas for the activities you enjoy most.

Carter Norwood

While Carter Norwood may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Ponce de Leon Inlet Lighthouse and Museum and Pirate's Island Adventure Golf.

Winthrop Holding

Though Winthrop Holding may not have many top sights, you can venture to the surrounding area to see attractions like Ponce de Leon Inlet Lighthouse and Museum and Dahlia Avenue Park.

Halifax Estates

When in Halifax Estates, you can plan a visit to Ponce de Leon Inlet Lighthouse and Museum and Pirate's Island Adventure Golf, some noteworthy sights in the nearby area.

Harbor Oaks

When in Harbor Oaks, you can plan a visit to Go-Kart City and Ponce Inlet Beach, some noteworthy sights in the nearby area.

Fly In Spruce Creek

While Fly In Spruce Creek isn't home to many top sights, Spruce Creek Country Club and Crane Lakes Golf and Country Club are some notable places to visit nearby.

Top Sanctuary On Spruce Creek Hotel Reviews

Frequently asked questions

What is Sanctuary On Spruce Creek like?
Travellers to the Sanctuary On Spruce Creek neighbourhood in Port Orange will be sure to enjoy their stay.
If I need to cancel my hotel reservation in Sanctuary On Spruce Creek, will I receive a refund?
Yes, you'll find most hotel room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of check in. If you have a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best deals available in Sanctuary On Spruce Creek.
What is there to do in this Port Orange neighbourhood?
Gamble Place, Spruce Creek Country Club and Airport Road Park are just a few of the places to visit in and around Sanctuary On Spruce Creek. Golf Club at Cypress Head and Crane Lakes Golf and Country Club are also worth a visit when you're out sightseeing in Port Orange.