Search Hotels in Santa Ana, Antigua Guatemala

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Our top choices for Santa Ana hotels

Hostal Casa Buho

Hostal Casa Buho
3.0 star property
Santa Ana
8.6 out of 10, Excellent, (23 reviews)
"A little too far from everything but as long as you have a car is ok plenty of parking there"
United States
Gustavo
The price is Rp808.561
Rp986.444 total
includes taxes & fees
21 Apr - 22 Apr
Hostal Casa Buho

Villas Santa Ana-Ricardo

Villas Santa Ana-Ricardo
3.5 star property
Santa Ana
8.8 out of 10, Excellent, (15 reviews)
"Space was clean and had a cozy vibe."
United States
Evelin
The price is Rp2.178.070
Rp2.657.245 total
includes taxes & fees
30 Apr - 1 May
Villas Santa Ana-Ricardo

Casa Buho B&B

Casa Buho B&B
3.0 star property
Santa Ana
9.2 out of 10, Wonderful, (51 reviews)
"Beautiful hotel with clean rooms and friendly staff. The only downsides are the distance to the center (a 30-minute walk) and the chickens and peacocks screaming early in the morning"
United States
Patrick
The price is Rp1.115.107
Rp1.360.431 total
includes taxes & fees
6 Apr - 7 Apr
Casa Buho B&B

Hilton Guatemala City

Hilton Guatemala City
4.5 star property
25.9 km from Santa Ana
8.6 out of 10, Excellent, (704 reviews)
"The hotel property in excellent condition and very quiet and safe."
United States
Roger
The price is Rp1.880.018
Rp2.293.622 total
includes taxes & fees
26 Apr - 27 Apr
Hilton Guatemala City

AC Hotel by Marriott Guatemala City

AC Hotel by Marriott Guatemala City
4.0 star property
26.4 km from Santa Ana
8.6 out of 10, Excellent, (1,000 reviews)
"Convenient Great location Great for business travel "
United States
Patricia
The price is Rp2.006.541
Rp2.447.981 total
includes taxes & fees
26 Apr - 27 Apr
AC Hotel by Marriott Guatemala City

Hotel Vista Quince

Hotel Vista Quince
5.0 star property
25.5 km from Santa Ana
8.6 out of 10, Excellent, (247 reviews)
"We really enjoyed our stay, everything was great- we will be returning "
United States
Lucy
The price is Rp2.139.858
Rp2.610.627 total
includes taxes & fees
6 Apr - 7 Apr
Hotel Vista Quince

Villas Santander - Deluxe Stay

Villas Santander - Deluxe Stay
3.0 star property
24.7 km from Santa Ana
7.4 out of 10, Good, (244 reviews)
"Spotless room, courteous staff "
United States
Walter
The price is Rp599.696
Rp731.630 total
includes taxes & fees
5 Apr - 6 Apr
Villas Santander - Deluxe Stay

Villa Sicilia

Villa Sicilia
2.0 star property
24 km from Santa Ana
8.0 out of 10, Very good, (124 reviews)
"It was nice to have a restaurant on site with a cooler of drink options for purchase as well! "
United States
Lynn
The price is Rp436.934
Rp533.059 total
includes taxes & fees
5 Apr - 6 Apr
Villa Sicilia

Ever Green Hotel

Ever Green Hotel
3.5 star property
23.8 km from Santa Ana
9.0 out of 10, Wonderful, (74 reviews)
"Excelente"
Mexico
Guillermo
The price is Rp1.399.291
Rp1.707.135 total
includes taxes & fees
3 Apr - 4 Apr
Ever Green Hotel

Hotel Antigua Inn

Hotel Antigua Inn
3.5 star property
23.8 km from Santa Ana
8.2 out of 10, Very good, (70 reviews)
"Exelente hotel and location and friendly people. "
United States
Rudy A
The price is Rp1.327.159
Rp1.619.134 total
includes taxes & fees
25 Apr - 26 Apr
Hotel Antigua Inn

La Inmaculada Hotel

La Inmaculada Hotel
3.5 star property
23.7 km from Santa Ana
9.2 out of 10, Wonderful, (632 reviews)
"Great staff, convenient location, hotel has everything it offers."
United States
Colin
The price is Rp1.657.272
Rp2.021.872 total
includes taxes & fees
5 Apr - 6 Apr
La Inmaculada Hotel

Hotel Ciudad Vieja

Hotel Ciudad Vieja
3.0 star property
23.7 km from Santa Ana
9.2 out of 10, Wonderful, (230 reviews)
"Excellent spot! Garden oasis!"
United States
kathleen
The price is Rp1.357.281
Rp1.655.883 total
includes taxes & fees
8 Apr - 9 Apr
Hotel Ciudad Vieja

Meraki Boutique Hotel

Meraki Boutique Hotel
3.5 star property
23.4 km from Santa Ana
9.0 out of 10, Wonderful, (427 reviews)
"It is a boutique hotel with comfortable beds, good AC and a great breakfast. The rooms are small but comfortable and the hotel is well run and in a good location. The staff are very helpful and the 24 hour front desk ensured that I got to the airport at 3:30AM. I'll stay there again. "
United States
Gary
The price is Rp1.306.931
Rp1.594.456 total
includes taxes & fees
2 May - 3 May
Meraki Boutique Hotel

Hotel Santander Plaza

Hotel Santander Plaza
3.5 star property
23.3 km from Santa Ana
8.2 out of 10, Very good, (596 reviews)
"The location is very good, with many options nearby, including restaurants, bakeries, and convenience stores. Breakfast was good and added a nice level of convenience to the stay."
United States
Servio
The price is Rp1.669.932
Rp2.037.317 total
includes taxes & fees
16 Apr - 17 Apr
Hotel Santander Plaza

Clarion Suites Guatemala City

Clarion Suites Guatemala City
4.0 star property
23.3 km from Santa Ana
9.2 out of 10, Wonderful, (1,001 reviews)
"Rooms were very clean and spacious. The breakfast was excellent. Definitely worth the price."
United States
Ryan
The price is Rp1.429.119
Rp1.743.525 total
includes taxes & fees
5 Apr - 6 Apr
Clarion Suites Guatemala City

Good Hotel Guatemala City

Good Hotel Guatemala City
3.0 star property
23.9 km from Santa Ana
9.4 out of 10, Exceptional, (308 reviews)
"Nice place to stay in Guatemala City."
United States
Shane
The price is Rp2.076.175
Rp2.532.933 total
includes taxes & fees
19 Apr - 20 Apr
Good Hotel Guatemala City

Hyatt Centric Guatemala City

Hyatt Centric Guatemala City
4.5 star property
23.3 km from Santa Ana
9.4 out of 10, Exceptional, (866 reviews)
"Very nice hotel clean and friendly staff"
United States
jose
The price is Rp2.462.535
Rp3.004.293 total
includes taxes & fees
4 Apr - 5 Apr
Hyatt Centric Guatemala City

Best Western Plus Hotel Stofella

Best Western Plus Hotel Stofella
4.0 star property
23.3 km from Santa Ana
8.8 out of 10, Excellent, (1,007 reviews)
"Great location Clean rooms. Good breakfast Friendly staff. "
United States
Andrew
The price is Rp1.557.681
Rp1.900.398 total
includes taxes & fees
17 Apr - 18 Apr
Best Western Plus Hotel Stofella

InterContinental Real Guatemala by IHG

InterContinental Real Guatemala by IHG
5.0 star property
23.2 km from Santa Ana
9.2 out of 10, Wonderful, (1,002 reviews)
"Huge room and amazing breakfast! "
United States
Yulia
The price is Rp2.377.620
Rp3.107.889 total
includes taxes & fees
10 Apr - 11 Apr
InterContinental Real Guatemala by IHG

Hotel Royal Palace

Hotel Royal Palace
3.0 star property
24.5 km from Santa Ana
8.2 out of 10, Very good, (152 reviews)
"Clean and quiet room. Helpful courteous stafff"
United States
valden
The price is Rp1.564.304
Rp1.908.380 total
includes taxes & fees
6 Apr - 7 Apr
Hotel Royal Palace
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Historic Center

If you're spending some time in Historic Center, Central Park and Santa Catalina Arch are top sights worth seeing.

Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

Top Santa Ana Hotel Reviews

Frequently asked questions

What's it like in Santa Ana?
Travellers to the Santa Ana neighbourhood in Antigua Guatemala will be sure to enjoy their stay.
What's a favourite place to stay in Santa Ana?
Based on Expedia customer reviews, Casa Buho B&B is the highest ranked property in Santa Ana. This hotel offers a restaurant and free parking. Another top choice in the area is Hostal Casa Buho.
How many hotels will I be able to find in Santa Ana?
If you're searching for places to stay in Antigua Guatemala, choose from one of Expedia's 14 hotels and other accommodation options in Santa Ana.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view top deals in Santa Ana.
What are the top things to see and do in Santa Ana?
House of the Giants, Santa Clara Convent and Jade Maya Factory and Museum are just a few of the places to visit in and around Santa Ana. While you're out sightseeing in Antigua Guatemala, make sure that you visit other sights such as Tanque La Unión or Museo del Hermano Pedro.