Santa Cruz Holidays

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to Rp16.000.000 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
A barren landscape with red soil and sparse yellow grass, a distant mountain range, and a clear blue sky.

Central North

You'll enjoy the waterfalls and riverfront in Central North. You might want to make time for a stop at Cine Teatro Cuiaba or Republic Square.

Find hotels in Central North

Top hotels in Santa Cruz

Delmond Hotel

Delmond Hotel

4 out of 5
Av. Andre Antonio Maggi, 1980 Cuiabá MT
Fully refundableReserve now, pay when you stay
The price is Rp1.098.520 per night from 22 Nov to 23 Nov
Rp1.098.520
Rp1.244.593 total
22 Nov - 23 Nov
includes taxes & fees
9.2/10 Wonderful! (942 reviews)
"Location"

Reviewed on 25 Oct 2026

Delmond Hotel
Amazon Aeroporto Hotel

Amazon Aeroporto Hotel

3 out of 5
Avenida Governador Joao Ponce de Arruda Varzea Grande Mato Grosso
Fully refundableReserve now, pay when you stay
The price is Rp2.163.395 per night from 13 Nov to 14 Nov
Rp2.163.395
Rp2.487.905 total
13 Nov - 14 Nov
includes taxes & fees
Amazon Aeroporto Hotel
HITS PANTANAL HOTEL AEROPORTO

HITS PANTANAL HOTEL AEROPORTO

3.5 out of 5
Av. Arthur Bernardes, nº 251 Varzea Grande Mato Grosso
Fully refundableReserve now, pay when you stay
The price is Rp859.743 per night from 6 Dec to 7 Dec
Rp859.743
Rp902.730 total
6 Dec - 7 Dec
includes taxes & fees
8.4/10 Very good! (635 reviews)
"The room was large and very clean and the bed was comfortable, although there was noise from other rooms as the walls were thin. The pool was great and of a good size. Breakfast was okay, the usual buffet offering. The free airport transfer was welcome!"

Reviewed on 21 Oct 2026

HITS PANTANAL HOTEL AEROPORTO
See all 132 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Cruz holiday package cost?
From just , you can custom build your Santa Cruz holiday package. Simply combine hotels, flights and car rentals and be rewarded with discounts.
How do I get a cheap travel package to Santa Cruz?
It's easy. Just bundle. Flights, hotels and rental cars — combine whatever you need into a Santa Cruz holiday package to save loads of cash. Score even more discounts when you include extras such as day tours to your booking. But that's not the only impressive part. You have the freedom to customize your trip your own way. We offer over 550 air carriers and 1,000,000 hotel options in all corners of the globe, so that everyone has an opportunity to travel and fulfil those holiday fantasies.
Where should I stay in Santa Cruz?
Tick Arena Pantanal off your must-see list and then stay moments from it. Soak up the exciting vibe around this major attraction and visit whenever you like!
How far in advance should I book my Santa Cruz holiday?
Browse Expedia to compare international flights as soon as possible. In many cases, you can purchase a ticket up to a year before departure. If it's too early for your preferred carrier, or you're booking late, don't worry. Cheap tickets to Santa Cruz sometimes appear within weeks of departure.
What does an Expedia Santa Cruz travel package include?
From hotels and airfares to car rentals, Expedia can help you create a Santa Cruz package that's ideal for you. Heading away for a week or longer? Look into a rental car, hotel and flight bundle. If you're taking a short break, an airfare and hotel deal could suit you better. Activities can also be added after you've booked. Our holiday packages make it easy to save and plan.
What should I know before booking a Santa Cruz travel package?
Locking in all the parts of your trip together is an excellent way to save. Bundle your airfares, rental cars and hotels into a tidy package. But hotels aren't your only option. Expedia offers all types of properties, including holiday rentals such as beach villas and city residences. You've got loads of choices!
Can I choose my airline with a Santa Cruz Expedia holiday package?
Definitely. Expedia has over 550 airline partners to pick from around the globe. With such a big range of choice, finding the perfect carrier to fly you to Santa Cruz will be a breeze.
If I'm not able to travel, can I cancel my Santa Cruz holiday package?
Yes, you can. We totally understand that even the best-laid plans can go awry, so we're here to help if you need to make changes to your Santa Cruz holiday package. You may be able to amend or cancel your itinerary for free if you've booked within 24 hours. Your airline, hotel or car rental company may charge you a fee if you booked more than 24 hours ago. Have a look at our Customer Service Portal for more information. Also, be sure to check your itinerary for the finer details on change fees.

Things to do

8 Days Jaguars and Pantanal Safari tour

8 Days Jaguars and Pantanal Safari tour

Rp98.144.752
per adult
8 Days Jaguars and Pantanal Safari tour
See all activities in Cuiabá
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.