Santa María Holidays
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to Rp16.000.000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Top hotels in Santa María
Sun Hotel
Encarnacion Itapúa
Rp1.043.261
Rp1.147.569 total
13 Aug - 14 Aug
includes taxes & fees
9/10 Wonderful! (133 reviews)
"Muy bien ubicado"
Reviewed on 9 Aug 2026
Carnaval Hotel Casino
Av. Irrazabal, 750 Encarnacion
Rp1.205.617
Rp1.326.179 total
16 Aug - 17 Aug
includes taxes & fees
9.4/10 Exceptional! (204 reviews)
"Muuuuy recomendado. Buenos amenities y buenisisima ubicación. Desayuno completisimo."
Reviewed on 19 Jul 2026
Alula Hotel Encarnacion
1848 Gral Aquino Encarnación Itapúa
Fully refundableReserve now, pay when you stay
Rp1.515.519
Rp1.667.071 total
13 Aug - 14 Aug
includes taxes & fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
What to do in Santa María
Full-day guided adventure in the Misiones jungle
Rp6.864.700
per adult
Frequently asked questions
How much does a Santa María holiday package cost?
Offering great value package deals on Expedia, you'll be pleasantly surprised at how much a holiday to Santa María costs! Our packages make travel planning easier and save you more.
What are the cheapest months to go to Santa María?
January, February and April are the best times to search for cheap Santa María holiday packages. Opting to travel in quieter months means you can usually find better prices on flights and hotels.
How many days is enough for Santa María?
The ideal length for your Santa María holiday depends on what you'd like to see and do. Typically, a handful of days to a week will give you plenty of time to check out all the main attractions and explore some hidden spots along the way.
How to find the best Santa María package deals?
Use Expedia's handy filters to find some fabulous Santa María package deals. When you start your search, just set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your trip for midweek, or look for Santa María package deals in the off-peak season. Switch up your travel dates and you may land even bigger discounts. As a rule of thumb, it's usually best to lock in your holiday package well in advance.
Is it cheaper to book a Santa María holiday as a package?
An Expedia holiday package could save you hundreds of dollars when compared to booking hotels and flights separately. Better still, you can customise your Santa Marían escape to fit your exact needs. Pick your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.
When to book a holiday package to Santa María?
If you have your Santa María holiday dates locked in, book as early as you can to snap up some terrific deals. With Expedia, you can often reserve some flights up to one year in advance. Prefer spontaneous trips? Our last-minute deals are great for setting off on a whim.
How to plan a trip to Santa María?
- Choose when to travel: Check your calendar and pack your bags. Your preferred time of year and the type of activities on offer will also help you decide when to escape to Santa María.
- Set a budget: Consider expenses like flights, transportation and food when working out how much to set aside for your trip to Santa María. Then, select a property that matches your budget, whether that's a low-cost stay or a swankier getaway.
- Work out your trip length: Think about how long you want to spend exploring Santa María. Plan your days so you can get to all the attractions and activities you're interested in at a leisurely pace.
- Bundle your hotel and flights: Awesome destination, check. Length of stay, check. Now all that's left is to find a Santa María holiday package that brings all your bookings together.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
