Santa Maria Holidays

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Where to stay in Santa Maria

Find the best Santa Maria areas and neighborhoods for the activities you enjoy most. Learn more about Santa Maria
Fachada colorida de estilo colonial, barrio de Santa Ana, Guayaquil, Ecuador

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

Find hotels in Ecuador

Top hotels in Santa Maria

Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG

3.5 out of 5
Av. de Las Américas,junto al Aeropuerto Guayaquil Guayas
Fully refundable
The price is Rp1.491.512 per night from 2 Apr to 3 Apr
Rp1.491.512
Rp1.683.036 total
2 Apr - 3 Apr
9.4/10 Exceptional! (1,014 reviews)
Business friendly and safe

Reviewed on 9 Mar 2026

Holiday Inn Guayaquil Airport by IHG
Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

4.5 out of 5
Calle Numa Pompilio Llona S N Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is Rp1.525.410 per night from 28 Mar to 29 Mar
Rp1.525.410
Rp1.720.324 total
28 Mar - 29 Mar
9.2/10 Wonderful! (1,009 reviews)
great experience

Reviewed on 5 Mar 2026

Wyndham Guayaquil Puerto Santa Ana
Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels

4 out of 5
Clemente Ballén 406 Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is Rp1.046.601 per night from 10 Apr to 11 Apr
Rp1.046.601
Rp1.193.718 total
10 Apr - 11 Apr
9.2/10 Wonderful! (1,012 reviews)
Clean room great staff

Reviewed on 9 Mar 2026

Unipark by Oro Verde Hotels
See all 424 properties in Santa Maria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Maria holiday package cost?
Get set to book, because a getaway to Santa Maria starts from a tempting . When you combine your hotels, flights and car rentals into a travel package, you'll enjoy the lowest prices.
How do I get a cheap travel package to Santa Maria?
Bundle your hotels and flights with Expedia to save big on your next trip. With more than 550 air carriers and 1,000,000 hotels worldwide, your Santa Maria holiday package can be customized exactly to suit your travel style. With all that extra cash, why not add a few fun activities and tours? It's an easy way to unlock even more savings. Your dream holiday in Santa Maria is closer than you thought!
Where should I stay in Santa Maria?
Make sightseeing easy by staying someplace right around the corner from Santa Maria's biggest attractions. Malecon 2000 and Banco Pichincha Monumental Stadium are two visitor favourites.
How far in advance should I book my Santa Maria holiday?
Your safest bet is to book early. Airlines usually release flight tickets nearly 12 months prior to departure, and this is a great opportunity to score some rock-bottom prices. Just been told you should take your holiday time next month? No sweat. Expedia are never short on fantastic bargains to help you have the getaway of your dreams, at an affordable price.
What does an Expedia Santa Maria travel package include?
Select from any combination of flights, hotels and rental cars. Once you've made your booking, you can add activities and experiences. Want to pick your airfare class? That's easy to do too. The choice is all yours when it comes to arranging your dream Santa Maria escape.
What should I know before booking a Santa Maria travel package?
Get set to save with an Expedia travel package. Combine your flights, rental cars and hotels and enjoy exciting discounts. Hotels aren't your only choice, however. Book with us and choose from beach villas, creek-side mountain cabins and just about everything in between!
Can I choose my airline with a Santa Maria Expedia holiday package?
Expedia offers access to more than 550 airline partners globally, so you certainly can. Just pick your preferred air carrier and put together your ideal Santa Maria escape.
If I'm not able to travel, can I cancel my Santa Maria holiday package?
Yes, you can cancel your Santa Maria booking if your travel plans have been upended. Whether you'll incur a fee or not depends on your airline, hotel or car rental company. It may be possible to cancel or change your booking for free if you booked in the last 24 hours. Head to our Customer Service Portal to learn more.

Popular places to visit

Seaside Malecon 2000 walkway with Santa Ana Hill, Ecuador

Santa Ana Hill

5/5(2 reviews)

Explore the great outdoors at Santa Ana Hill, a lovely green space in Guayaquil. While you're in the area, find time to visit its shops.

Santa Ana Hill

Mall del Sur

You can enjoy retail therapy at Mall del Sur during your stay in Guayaquil. While in this walkable area, find time to visit its shops.

Mall del Sur

San Marino Mall

During your visit to Guayaquil, you can do some window-shopping at San Marino Mall. Visit the area's cathedral or simply enjoy its seafood restaurants.

San Marino Mall

Things to do

City Winery - Two Hemispheres

Wine Tasting Experience with Tasting Menu

Rp1.085.148
per adult
100% of travellers recommend
Wine Tasting Experience with Tasting Menu
Half Day Walking Tour of Guayaquil Pearl of the Pacific

Half Day Walking Tour of Guayaquil Pearl of the Pacific

Rp1.682.400
per adult
Half Day Walking Tour of Guayaquil Pearl of the Pacific
Cocoa Farm

Small Group Guayaquil and Cocoa Farm Full-Day Tour

Rp3.028.320
per adult
Small Group Guayaquil and Cocoa Farm Full-Day Tour
See all activities in Guayaquil
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.