Search Hotels in Serenity Bay, Seneca

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Serenity Bay hotels

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
14 km from Serenity Bay
9.0 out of 10, Wonderful, (1001)
"Great place to stay. "
United States
Gene
The price is Rp1.814.414
Rp2.252.370 total
includes taxes & fees
15 Dec - 16 Dec
Lakeside Lodge Clemson

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
9.1 km from Serenity Bay
9.2 out of 10, Wonderful, (662)
"Great place to stay"
United States
Jose
The price is Rp1.691.234
Rp1.860.191 total
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn & Suites Seneca-Clemson Area

Rodeway Inn & Suites Walhalla

Rodeway Inn & Suites Walhalla
2.0 star property
7.4 km from Serenity Bay
7.6 out of 10, Good, (174)
"Comfortable, clean, convenient and well located near nature interests in the area. Perfect for our stay to do white water raft on the Chatooga. Great shower and comfortable beds."
United States
Cheryl
The price is Rp1.131.762
Rp1.261.914 total
includes taxes & fees
11 Jan - 12 Jan 2026
Rodeway Inn & Suites Walhalla

The Abernathy of Clemson

The Abernathy of Clemson
4.0 star property
15.7 km from Serenity Bay
9.6 out of 10, Exceptional, (557)
"location is amazing! "
United States
colleen
The Abernathy of Clemson

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown, 9.9 km from Serenity Bay
8.0 out of 10, Very good, (664)
"Friendly check in, clean room."
United States
connie
The price is Rp1.223.441
Rp1.444.910 total
includes taxes & fees
21 Dec - 22 Dec
Quality Inn Seneca Clemson Area US-123

The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
19.8 km from Serenity Bay
9.8 out of 10, Exceptional, (781)
"Clean room. Nice front desk concierge. Very cute hotel"
United States
Anisha
The price is Rp2.484.724
Rp2.758.045 total
includes taxes & fees
14 Dec - 15 Dec
The Inn at Patrick Square

Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG
2.5 star property
17.2 km from Serenity Bay
8.8 out of 10, Excellent, (950)
"Had a great stay at this hotel. Conveniently located near restaurants. "
United States
Kelly
The price is Rp1.967.768
Rp2.184.220 total
includes taxes & fees
2 Jan - 3 Jan 2026
Holiday Inn Express & Suites Clemson by IHG

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
18 km from Serenity Bay
9.8 out of 10, Exceptional, (50)
"The place was absolutely magnificent."
United States
David
The price is Rp1.481.494
Rp2.362.068 total
includes taxes & fees
12 Jan - 13 Jan 2026
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
16.7 km from Serenity Bay
8.2 out of 10, Very good, (1001)
" Clean room, breakfast, staff very nice."
United States
Maria Claudia
The price is Rp1.542.252
Rp1.711.899 total
includes taxes & fees
15 Dec - 16 Dec
Best Western Plus Clemson Hotel & Conference Center

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
16.5 km from Serenity Bay
8.2 out of 10, Very good, (1000)
"Great stay "
United States
Linda
The price is Rp1.542.252
Rp1.711.900 total
includes taxes & fees
21 Dec - 22 Dec
Comfort Inn & Suites Clemson - University Area

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
4.0 star property
16 km from Serenity Bay
9.8 out of 10, Exceptional, (743)
"Staff was amazing and our room was clean and comfortable. "
United States
Amanda R
The price is Rp2.818.244
Rp3.128.251 total
includes taxes & fees
14 Dec - 15 Dec
The Shepherd Hotel Downtown Clemson

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
2.5 star property
8.6 km from Serenity Bay
9.4 out of 10, Exceptional, (204)
"Nice hotel by the lake"
United States
Mike
The price is Rp1.914.290
Rp2.105.721 total
includes taxes & fees
21 Dec - 22 Dec
Fairfield Inn & Suites Seneca Clemson Univ Area

Carolina Camp Cedar

Carolina Camp Cedar
3.5 star property
27.9 km from Serenity Bay
The price is Rp1.602.897
Rp3.317.422 total
includes taxes & fees
14 Dec - 15 Dec
Carolina Camp Cedar

Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
8.8 km from Serenity Bay
8.4 out of 10, Very good, (641)
"The stay was amazing "
United States
Tabatha
The price is Rp1.485.656
Rp1.634.219 total
includes taxes & fees
26 Dec - 27 Dec
Best Western Seneca-Clemson

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
13.9 km from Serenity Bay
9.2 out of 10, Wonderful, (791)
"Staff was very friendly. Everything was very clean. Very quite in room"
United States
Dianna
The price is Rp1.584.699
Rp1.743.169 total
includes taxes & fees
21 Dec - 22 Dec
Tru by Hilton Seneca Clemson

Clemson Memorabilia House

Clemson Memorabilia House
3.0 star property
18.8 km from Serenity Bay
9.8 out of 10, Exceptional, (9)
"We enjoyed our stay, it was the perfect size for our family of four. "
United States
Ashley
The price is Rp1.384.108
Rp3.850.154 total
includes taxes & fees
14 Dec - 15 Dec
Clemson Memorabilia House

Courtyard Marriott Clemson

Courtyard Marriott Clemson
3.0 star property
17.5 km from Serenity Bay
9.0 out of 10, Wonderful, (523)
"Great property "
United States
Shaun
The price is Rp1.786.000
Rp1.982.460 total
includes taxes & fees
21 Dec - 22 Dec
Courtyard Marriott Clemson

Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast
4.0 star property
22.8 km from Serenity Bay
10.0 out of 10, Exceptional, (78)
"The owners are amazing. Comfy rooms, stellar breakfast and good people. "
United States
Renee
The price is Rp2.621.737
Rp2.910.128 total
includes taxes & fees
14 Dec - 15 Dec
Liberty Hall Bed and Breakfast

Hampton Inn Clemson-University Area

Hampton Inn Clemson-University Area
2.5 star property
14.7 km from Serenity Bay
8.8 out of 10, Excellent, (620)
"Room was awesome and great breakfast "
United States
Guy
The price is Rp1.686.777
Rp1.872.322 total
includes taxes & fees
24 Dec - 25 Dec
Hampton Inn Clemson-University Area

Days Inn by Wyndham Clemson

Days Inn by Wyndham Clemson
3.5 star property
17.3 km from Serenity Bay
7.0 out of 10, Good, (197)
"Rooms were clean. Check in was easy. TV and AC both worked great. Conveniently located to dining and shopping options. No issues or complaints. Would stay again. "
United States
Sean
The price is Rp1.409.956
Rp1.565.051 total
includes taxes & fees
15 Dec - 16 Dec
Days Inn by Wyndham Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Serenity Bay

Find the best Serenity Bay areas for the activities you enjoy most.

Downtown

If you're spending some time in Downtown, Seneca Historic District and The Gauntlet are top sights worth seeing.

Pine Ridge Point

If you're looking for some top things to see and do in Pine Ridge Point and surrounding area, you can visit Lake Keowee and World of Energy.

Indian Oaks

While Indian Oaks may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like The Gauntlet and Seneca Historic District.

Keowee Plantation

While Keowee Plantation isn't home to many top sights, Seneca Historic District and Keowee Reservoir are some notable places to visit nearby.

Top Serenity Bay Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

What is Serenity Bay like?
You'll be sure to have fun exploring Seneca's Serenity Bay neighbourhood. Consider a visit to Lake Keowee as part of your Serenity Bay travel plans.
How many hotels can I expect to find in Serenity Bay?
When you want to put your feet up after a day of exploring the sights in Seneca, you can choose from 12 Expedia hotels and other accommodation options in Serenity Bay.
If I need to cancel my hotel reservation in Serenity Bay, will I receive a refund?
Yes! The majority of room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and get a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to view top deals in Serenity Bay.
What are the top things to see and do in Serenity Bay?
Lake Keowee is an attraction you might want to check out while you're in Serenity Bay. Make a stop at Keowee Key Golf Course and World of Energy while you're sightseeing around the area.